NOS3 c.-51-665C>T

Variant ID: 7-150690176-C-T

NM_000603.4(NOS3):c.-51-665C>T

This variant was identified in 85 publications

View GRCh38 version.




Publications:


Association of nitric oxide synthase gene polymorphism with asthma: A systematic review and meta-analysis.

The Clinical Respiratory Journal
Fan, Zeru Z; Liu, Tao T; Na, Wei W
Publication Date: 2023-04-19

Variant appearance in text: rs3918226
PubMed Link: 37076778
Variant Present in the following documents:
  • Main text
  • CRJ-17-516.pdf
View BVdb publication page



FinnGen provides genetic insights from a well-phenotyped isolated population.

Nature
Kurki, Mitja I MI; Karjalainen, Juha J; Palta, Priit P; Sipilä, Timo P TP; Kristiansson, Kati K; Donner, Kati M KM; Reeve, Mary P MP; Laivuori, Hannele H; Aavikko, Mervi M; Kaunisto, Mari A MA; Loukola, Anu A; Lahtela, Elisa E; Mattsson, Hannele H; Laiho, Päivi P; Della Briotta Parolo, Pietro P; Lehisto, Arto A AA; Kanai, Masahiro M; Mars, Nina N; Rämö, Joel J; Kiiskinen, Tuomo T; Heyne, Henrike O HO; Veerapen, Kumar K; Rüeger, Sina S; Lemmelä, Susanna S; Zhou, Wei W; Ruotsalainen, Sanni S; Pärn, Kalle K; Hiekkalinna, Tero T; Koskelainen, Sami S; Paajanen, Teemu T; Llorens, Vincent V; Gracia-Tabuenca, Javier J; Siirtola, Harri H; Reis, Kadri K; Elnahas, Abdelrahman G AG; Sun, Benjamin B; Foley, Christopher N CN; Aalto-Setälä, Katriina K; Alasoo, Kaur K; Arvas, Mikko M; Auro, Kirsi K; Biswas, Shameek S; Bizaki-Vallaskangas, Argyro A; Carpen, Olli O; Chen, Chia-Yen CY; Dada, Oluwaseun A OA; Ding, Zhihao Z; Ehm, Margaret G MG; Eklund, Kari K; Färkkilä, Martti M; Finucane, Hilary H; Ganna, Andrea A; Ghazal, Awaisa A; Graham, Robert R RR; Green, Eric M EM; Hakanen, Antti A; Hautalahti, Marco M; Hedman, Åsa K ÅK; Hiltunen, Mikko M; Hinttala, Reetta R; Hovatta, Iiris I; Hu, Xinli X; Huertas-Vazquez, Adriana A; Huilaja, Laura L; Hunkapiller, Julie J; Jacob, Howard H; Jensen, Jan-Nygaard JN; Joensuu, Heikki H; John, Sally S; Julkunen, Valtteri V; Jung, Marc M; Junttila, Juhani J; Kaarniranta, Kai K; Kähönen, Mika M; Kajanne, Risto R; Kallio, Lila L; Kälviäinen, Reetta R; Kaprio, Jaakko J; , ; Kerimov, Nurlan N; Kettunen, Johannes J; Kilpeläinen, Elina E; Kilpi, Terhi T; Klinger, Katherine K; Kosma, Veli-Matti VM; Kuopio, Teijo T; Kurra, Venla V; Laisk, Triin T; Laukkanen, Jari J; Lawless, Nathan N; Liu, Aoxing A; Longerich, Simonne S; Mägi, Reedik R; Mäkelä, Johanna J; Mäkitie, Antti A; Malarstig, Anders A; Mannermaa, Arto A; Maranville, Joseph J; Matakidou, Athena A; Meretoja, Tuomo T; Mozaffari, Sahar V SV; Niemi, Mari E K MEK; Niemi, Marianna M; Niiranen, Teemu T; O Donnell, Christopher J CJ; Obeidat, Ma En ME; Okafo, George G; Ollila, Hanna M HM; Palomäki, Antti A; Palotie, Tuula T; Partanen, Jukka J; Paul, Dirk S DS; Pelkonen, Margit M; Pendergrass, Rion K RK; Petrovski, Slavé S; Pitkäranta, Anne A; Platt, Adam A; Pulford, David D; Punkka, Eero E; Pussinen, Pirkko P; Raghavan, Neha N; Rahimov, Fedik F; Rajpal, Deepak D; Renaud, Nicole A NA; Riley-Gillis, Bridget B; Rodosthenous, Rodosthenis R; Saarentaus, Elmo E; Salminen, Aino A; Salminen, Eveliina E; Salomaa, Veikko V; Schleutker, Johanna J; Serpi, Raisa R; Shen, Huei-Yi HY; Siegel, Richard R; Silander, Kaisa K; Siltanen, Sanna S; Soini, Sirpa S; Soininen, Hilkka H; Sul, Jae Hoon JH; Tachmazidou, Ioanna I; Tasanen, Kaisa K; Tienari, Pentti P; Toppila-Salmi, Sanna S; Tukiainen, Taru T; Tuomi, Tiinamaija T; Turunen, Joni A JA; Ulirsch, Jacob C JC; Vaura, Felix F; Virolainen, Petri P; Waring, Jeffrey J; Waterworth, Dawn D; Yang, Robert R; Nelis, Mari M; Reigo, Anu A; Metspalu, Andres A; Milani, Lili L; Esko, Tõnu T; Fox, Caroline C; Havulinna, Aki S AS; Perola, Markus M; Ripatti, Samuli S; Jalanko, Anu A; Laitinen, Tarja T; Mäkelä, Tomi P TP; Plenge, Robert R; McCarthy, Mark M; Runz, Heiko H; Daly, Mark J MJ; Palotie, Aarno A
Publication Date: 2023-01

Variant appearance in text: rs3918226
PubMed Link: 36653562
Variant Present in the following documents:
  • 41586_2022_5473_MOESM4_ESM.xlsx, sheet 8
View BVdb publication page



Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants.

Nature Genetics
Aragam, Krishna G KG; Jiang, Tao T; Goel, Anuj A; Kanoni, Stavroula S; Wolford, Brooke N BN; Atri, Deepak S DS; Weeks, Elle M EM; Wang, Minxian M; Hindy, George G; Zhou, Wei W; Grace, Christopher C; Roselli, Carolina C; Marston, Nicholas A NA; Kamanu, Frederick K FK; Surakka, Ida I; Venegas, Loreto Muñoz LM; Sherliker, Paul P; Koyama, Satoshi S; Ishigaki, Kazuyoshi K; Åsvold, Bjørn O BO; Brown, Michael R MR; Brumpton, Ben B; de Vries, Paul S PS; Giannakopoulou, Olga O; Giardoglou, Panagiota P; Gudbjartsson, Daniel F DF; Güldener, Ulrich U; Haider, Syed M Ijlal SMI; Helgadottir, Anna A; Ibrahim, Maysson M; Kastrati, Adnan A; Kessler, Thorsten T; Kyriakou, Theodosios T; Konopka, Tomasz T; Li, Ling L; Ma, Lijiang L; Meitinger, Thomas T; Mucha, Sören S; Munz, Matthias M; Murgia, Federico F; Nielsen, Jonas B JB; Nöthen, Markus M MM; Pang, Shichao S; Reinberger, Tobias T; Schnitzler, Gavin G; Smedley, Damian D; Thorleifsson, Gudmar G; von Scheidt, Moritz M; Ulirsch, Jacob C JC; , ; , ; Arnar, David O DO; Burtt, Noël P NP; Costanzo, Maria C MC; Flannick, Jason J; Ito, Kaoru K; Jang, Dong-Keun DK; Kamatani, Yoichiro Y; Khera, Amit V AV; Komuro, Issei I; Kullo, Iftikhar J IJ; Lotta, Luca A LA; Nelson, Christopher P CP; Roberts, Robert R; Thorgeirsson, Gudmundur G; Thorsteinsdottir, Unnur U; Webb, Thomas R TR; Baras, Aris A; Björkegren, Johan L M JLM; Boerwinkle, Eric E; Dedoussis, George G; Holm, Hilma H; Hveem, Kristian K; Melander, Olle O; Morrison, Alanna C AC; Orho-Melander, Marju M; Rallidis, Loukianos S LS; Ruusalepp, Arno A; Sabatine, Marc S MS; Stefansson, Kari K; Zalloua, Pierre P; Ellinor, Patrick T PT; Farrall, Martin M; Danesh, John J; Ruff, Christian T CT; Finucane, Hilary K HK; Hopewell, Jemma C JC; Clarke, Robert R; Gupta, Rajat M RM; Erdmann, Jeanette J; Samani, Nilesh J NJ; Schunkert, Heribert H; Watkins, Hugh H; Willer, Cristen J CJ; Deloukas, Panos P; Kathiresan, Sekar S; Butterworth, Adam S AS; ,
Publication Date: 2022-12

Variant appearance in text: rs3918226
PubMed Link: 36474045
Variant Present in the following documents:
  • 41588_2022_Article_1233.pdf
View BVdb publication page



Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo.

Ejhaem
Safa, Firas F; Rasmussen, Terri T; Lobelle-Rich, Patricia P; Collier, Stephanie S; Milligan, Nicholas N; Schmeig, John J; Schmid, Janet J; Wiewiorowski, Carol C; Totaro, Denise D; Brown, Theresa C TC; Satyavarapu, Ishwarya I; Badoo, Melody M; Ungerleider, Nathan N; Flemington, Erik K EK; Safah, Hana H; Saba, Nakhle S NS
Publication Date: 2022-11

Variant appearance in text: rs3918226
PubMed Link: 36467812
Variant Present in the following documents:
  • JHA2-3-1326-s001.xlsx, sheet 1
View BVdb publication page



The causal association between maternal smoking around birth on childhood asthma: A Mendelian randomization study.

Frontiers In Public Health
Ding, Zijun Z; Pang, Lei L; Chai, Hongqiang H; Li, Fei F; Wu, Ming M
Publication Date: 2022

Variant appearance in text: rs3918226
PubMed Link: 36408054
Variant Present in the following documents:
  • Main text
  • fpubh-10-1059195.pdf
View BVdb publication page



A protective erythropoietin evolutionary landscape, NLRP3 inflammasome regulation, and multisystem inflammatory syndrome in children.

Human Cell
Papadopoulos, Konstantinos I KI; Papadopoulou, Alexandra A; Aw, Tar-Choon TC
Publication Date: 2022-10-31

Variant appearance in text: rs3918226
PubMed Link: 36310304
Variant Present in the following documents:
  • Main text
  • 13577_2022_Article_819.pdf
View BVdb publication page



Genetic Factors for Coronary Heart Disease and Their Mechanisms: A Meta-Analysis and Comprehensive Review of Common Variants from Genome-Wide Association Studies.

Diagnostics (Basel, Switzerland)
Zarkasi, Khairul Anwar KA; Abdullah, Noraidatulakma N; Abdul Murad, Nor Azian NA; Ahmad, Norfazilah N; Jamal, Rahman R
Publication Date: 2022-10-21

Variant appearance in text: rs3918226
PubMed Link: 36292250
Variant Present in the following documents:
  • diagnostics-12-02561.pdf
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Genetic risk factors have a substantial impact on healthy life years.

Nature Medicine
Jukarainen, Sakari S; Kiiskinen, Tuomo T; Kuitunen, Sara S; Havulinna, Aki S AS; Karjalainen, Juha J; Cordioli, Mattia M; Rämö, Joel T JT; Mars, Nina N; , ; Samocha, Kaitlin E KE; Ollila, Hanna M HM; Pirinen, Matti M; Ganna, Andrea A
Publication Date: 2022-09

Variant appearance in text: rs3918226
PubMed Link: 36097220
Variant Present in the following documents:
  • 41591_2022_Article_1957.pdf
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KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress.

Nature Communications
Moonen, Jan-Renier JR; Chappell, James J; Shi, Minyi M; Shinohara, Tsutomu T; Li, Dan D; Mumbach, Maxwell R MR; Zhang, Fan F; Nair, Ramesh V RV; Nasser, Joseph J; Mai, Daniel H DH; Taylor, Shalina S; Wang, Lingli L; Metzger, Ross J RJ; Chang, Howard Y HY; Engreitz, Jesse M JM; Snyder, Michael P MP; Rabinovitch, Marlene M
Publication Date: 2022-08-23

Variant appearance in text: rs3918226
PubMed Link: 35999210
Variant Present in the following documents:
  • Main text
  • 41467_2022_Article_32566.pdf
View BVdb publication page



Management of Hypertension in the Elderly and Frail Patient.

Drugs & Aging
Guasti, Luigina L; Ambrosetti, Marco M; Ferrari, Marco M; Marino, Franca F; Ferrini, Marc M; Sudano, Isabella I; Tanda, Maria Laura ML; Parrini, Iris I; Asteggiano, Riccardo R; Cosentino, Marco M
Publication Date: 2022-10

Variant appearance in text: rs3918226
PubMed Link: 35904720
Variant Present in the following documents:
  • Main text
  • 40266_2022_Article_966.pdf
View BVdb publication page



Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk.

Nature Genetics
Turner, Adam W AW; Hu, Shengen Shawn SS; Mosquera, Jose Verdezoto JV; Ma, Wei Feng WF; Hodonsky, Chani J CJ; Wong, Doris D; Auguste, Gaëlle G; Song, Yipei Y; Sol-Church, Katia K; Farber, Emily E; Kundu, Soumya S; Kundaje, Anshul A; Lopez, Nicolas G NG; Ma, Lijiang L; Ghosh, Saikat Kumar B SKB; Onengut-Gumuscu, Suna S; Ashley, Euan A EA; Quertermous, Thomas T; Finn, Aloke V AV; Leeper, Nicholas J NJ; Kovacic, Jason C JC; Björkegren, Johan L M JLM; Zang, Chongzhi C; Miller, Clint L CL
Publication Date: 2022-06

Variant appearance in text: rs3918226
PubMed Link: 35590109
Variant Present in the following documents:
  • Main text
  • nihms-1794783.pdf
View BVdb publication page



U-shaped association of uric acid to overall-cause mortality and its impact on clinical management of hyperuricemia.

Redox Biology
Crawley, William T WT; Jungels, Cyprien G CG; Stenmark, Kurt R KR; Fini, Mehdi A MA
Publication Date: 2022-05

Variant appearance in text: rs3918226
PubMed Link: 35228125
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Polygenic risk for coronary artery disease in the Scottish and English population.

Bmc Cardiovascular Disorders
Yang, Chuhua C; Starnecker, Fabian F; Pang, Shichao S; Chen, Zhifen Z; Güldener, Ulrich U; Li, Ling L; Heinig, Matthias M; Schunkert, Heribert H
Publication Date: 2021-12-07

Variant appearance in text: rs3918226
PubMed Link: 34876023
Variant Present in the following documents:
  • 12872_2021_2398_MOESM1_ESM.pdf
View BVdb publication page



Diabetic kidney disease: Are the reported associations with single-nucleotide polymorphisms disease-specific?

World Journal Of Diabetes
Saracyn, Marek M; Kisiel, Bartłomiej B; Franaszczyk, Maria M; Brodowska-Kania, Dorota D; Żmudzki, Wawrzyniec W; Małecki, Robert R; Niemczyk, Longin L; Dyrla, Przemysław P; Kamiński, Grzegorz G; Płoski, Rafał R; Niemczyk, Stanisław S
Publication Date: 2021-10-15

Variant appearance in text: rs3918226
PubMed Link: 34754377
Variant Present in the following documents:
  • Main text
  • WJD-12-1765.pdf
View BVdb publication page



Correction: The genetic risk for hypertension is lower among the Hungarian Roma population compared to the general population.

Plos One
,
Publication Date: 2021

Variant appearance in text: rs3918226
PubMed Link: 34283866
Variant Present in the following documents:
  • pone.0255129.s002.pdf
  • pone.0255129.s001.pdf
View BVdb publication page



The Role of Single Nucleotide Variants of NOS1, NOS2, and NOS3 Genes in the Development of the Phenotype of Migraine and Arterial Hypertension.

Brain Sciences
Moskaleva, Polina V PV; Shnayder, Natalya A NA; Petrova, Marina M MM; Kaskaeva, Daria S DS; Gavrilyuk, Oksana A OA; Radostev, Sergey V SV; Garganeeva, Natalia P NP; Sharavii, Victoria B VB; Vaiman, Elena E EE; Nasyrova, Regina F RF
Publication Date: 2021-06-07

Variant appearance in text: rs3918226
PubMed Link: 34200123
Variant Present in the following documents:
  • Main text
  • brainsci-11-00753.pdf
View BVdb publication page



The Role of Single-Nucleotide Variants of NOS1, NOS2, and NOS3 Genes in the Comorbidity of Arterial Hypertension and Tension-Type Headache.

Molecules (Basel, Switzerland)
Shnayder, Natalia A NA; Petrova, Marina M MM; Moskaleva, Polina V PV; Shesternya, Pavel A PA; Pozhilenkova, Elena A EA; Nasyrova, Regina F RF
Publication Date: 2021-03-12

Variant appearance in text: rs3918226
PubMed Link: 33809023
Variant Present in the following documents:
  • Main text
  • molecules-26-01556.pdf
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Genetics of 35 blood and urine biomarkers in the UK Biobank.

Nature Genetics
Sinnott-Armstrong, Nasa N; Tanigawa, Yosuke Y; Amar, David D; Mars, Nina N; Benner, Christian C; Aguirre, Matthew M; Venkataraman, Guhan Ram GR; Wainberg, Michael M; Ollila, Hanna M HM; Kiiskinen, Tuomo T; Havulinna, Aki S AS; Pirruccello, James P JP; Qian, Junyang J; Shcherbina, Anna A; , ; Rodriguez, Fatima F; Assimes, Themistocles L TL; Agarwala, Vineeta V; Tibshirani, Robert R; Hastie, Trevor T; Ripatti, Samuli S; Pritchard, Jonathan K JK; Daly, Mark J MJ; Rivas, Manuel A MA
Publication Date: 2021-02

Variant appearance in text: NOS3: -51-665C>T; rs3918226
PubMed Link: 33462484
Variant Present in the following documents:
  • NIHMS1651539-supplement-2.xlsx, sheet 21
View BVdb publication page



Cardiovascular risk factor mediation of the effects of education and Genetic Risk Score on cardiovascular disease: a prospective observational cohort study of the Framingham Heart Study.

Bmj Open
Powell, Katie L KL; Stephens, Sebastien R SR; Stephens, Alexandre S AS
Publication Date: 2021-01-12

Variant appearance in text: rs3918226
PubMed Link: 33436477
Variant Present in the following documents:
  • bmjopen-2020-045210.draft_revisions.pdf
View BVdb publication page



Analysis of NOS Gene Polymorphisms in Relation to Cluster Headache and Predisposing Factors in Sweden.

Brain Sciences
Ran, Caroline C; Michalska, Julia M JM; Fourier, Carmen C; Sjöstrand, Christina C; Waldenlind, Elisabet E; Steinberg, Anna A; Belin, Andrea C AC
Publication Date: 2020-12-31

Variant appearance in text: rs3918226
PubMed Link: 33396232
Variant Present in the following documents:
  • Main text
View BVdb publication page



Human Nitric Oxide Synthase-Its Functions, Polymorphisms, and Inhibitors in the Context of Inflammation, Diabetes and Cardiovascular Diseases.

International Journal Of Molecular Sciences
Król, Magdalena M; Kepinska, Marta M
Publication Date: 2020-12-23

Variant appearance in text: rs3918226
PubMed Link: 33374571
Variant Present in the following documents:
  • Main text
  • ijms-22-00056.pdf
View BVdb publication page



Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.

Nature Genetics
Surendran, Praveen P; Feofanova, Elena V EV; Lahrouchi, Najim N; Ntalla, Ioanna I; Karthikeyan, Savita S; Cook, James J; Chen, Lingyan L; Mifsud, Borbala B; Yao, Chen C; Kraja, Aldi T AT; Cartwright, James H JH; Hellwege, Jacklyn N JN; Giri, Ayush A; Tragante, Vinicius V; Thorleifsson, Gudmar G; Liu, Dajiang J DJ; Prins, Bram P BP; Stewart, Isobel D ID; Cabrera, Claudia P CP; Eales, James M JM; Akbarov, Artur A; Auer, Paul L PL; Bielak, Lawrence F LF; Bis, Joshua C JC; Braithwaite, Vickie S VS; Brody, Jennifer A JA; Daw, E Warwick EW; Warren, Helen R HR; Drenos, Fotios F; Nielsen, Sune Fallgaard SF; Faul, Jessica D JD; Fauman, Eric B EB; Fava, Cristiano C; Ferreira, Teresa T; Foley, Christopher N CN; Franceschini, Nora N; Gao, He H; Giannakopoulou, Olga O; Giulianini, Franco F; Gudbjartsson, Daniel F DF; Guo, Xiuqing X; Harris, Sarah E SE; Havulinna, Aki S AS; Helgadottir, Anna A; Huffman, Jennifer E JE; Hwang, Shih-Jen SJ; Kanoni, Stavroula S; Kontto, Jukka J; Larson, Martin G MG; Li-Gao, Ruifang R; Lindström, Jaana J; Lotta, Luca A LA; Lu, Yingchang Y; Luan, Jian'an J; Mahajan, Anubha A; Malerba, Giovanni G; Masca, Nicholas G D NGD; Mei, Hao H; Menni, Cristina C; Mook-Kanamori, Dennis O DO; Mosen-Ansorena, David D; Müller-Nurasyid, Martina M; Paré, Guillaume G; Paul, Dirk S DS; Perola, Markus M; Poveda, Alaitz A; Rauramaa, Rainer R; Richard, Melissa M; Richardson, Tom G TG; Sepúlveda, Nuno N; Sim, Xueling X; Smith, Albert V AV; Smith, Jennifer A JA; Staley, James R JR; Stanáková, Alena A; Sulem, Patrick P; Thériault, Sébastien S; Thorsteinsdottir, Unnur U; Trompet, Stella S; Varga, Tibor V TV; Velez Edwards, Digna R DR; Veronesi, Giovanni G; Weiss, Stefan S; Willems, Sara M SM; Yao, Jie J; Young, Robin R; Yu, Bing B; Zhang, Weihua W; Zhao, Jing-Hua JH; Zhao, Wei W; Zhao, Wei W; Evangelou, Evangelos E; Aeschbacher, Stefanie S; Asllanaj, Eralda E; Blankenberg, Stefan S; Bonnycastle, Lori L LL; Bork-Jensen, Jette J; Brandslund, Ivan I; Braund, Peter S PS; Burgess, Stephen S; Cho, Kelly K; Christensen, Cramer C; Connell, John J; Mutsert, Renée de R; Dominiczak, Anna F AF; Dörr, Marcus M; Eiriksdottir, Gudny G; Farmaki, Aliki-Eleni AE; Gaziano, J Michael JM; Grarup, Niels N; Grove, Megan L ML; Hallmans, Göran G; Hansen, Torben T; Have, Christian T CT; Heiss, Gerardo G; Jørgensen, Marit E ME; Jousilahti, Pekka P; Kajantie, Eero E; Kamat, Mihir M; Käräjämäki, AnneMari A; Karpe, Fredrik F; Koistinen, Heikki A HA; Kovesdy, Csaba P CP; Kuulasmaa, Kari K; Laatikainen, Tiina T; Lannfelt, Lars L; Lee, I-Te IT; Lee, Wen-Jane WJ; , ; Linneberg, Allan A; Martin, Lisa W LW; Moitry, Marie M; Nadkarni, Girish G; Neville, Matt J MJ; Palmer, Colin N A CNA; Papanicolaou, George J GJ; Pedersen, Oluf O; Peters, James J; Poulter, Neil N; Rasheed, Asif A; Rasmussen, Katrine L KL; Rayner, N William NW; Mägi, Reedik R; Renström, Frida F; Rettig, Rainer R; Rossouw, Jacques J; Schreiner, Pamela J PJ; Sever, Peter S PS; Sigurdsson, Emil L EL; Skaaby, Tea T; Sun, Yan V YV; Sundstrom, Johan J; Thorgeirsson, Gudmundur G; Esko, Tõnu T; Trabetti, Elisabetta E; Tsao, Philip S PS; Tuomi, Tiinamaija T; Turner, Stephen T ST; Tzoulaki, Ioanna I; Vaartjes, Ilonca I; Vergnaud, Anne-Claire AC; Willer, Cristen J CJ; Wilson, Peter W F PWF; Witte, Daniel R DR; Yonova-Doing, Ekaterina E; Zhang, He H; Aliya, Naheed N; Almgren, Peter P; Amouyel, Philippe P; Asselbergs, Folkert W FW; Barnes, Michael R MR; Blakemore, Alexandra I AI; Boehnke, Michael M; Bots, Michiel L ML; Bottinger, Erwin P EP; Buring, Julie E JE; Chambers, John C JC; Chen, Yii-Der Ida YI; Chowdhury, Rajiv R; Conen, David D; Correa, Adolfo A; Davey Smith, George G; Boer, Rudolf A de RA; Deary, Ian J IJ; Dedoussis, George G; Deloukas, Panos P; Di Angelantonio, Emanuele E; Elliott, Paul P; , ; , ; Felix, Stephan B SB; Ferrières, Jean J; Ford, Ian I; Fornage, Myriam M; Franks, Paul W PW; Franks, Stephen S; Frossard, Philippe P; Gambaro, Giovanni G; Gaunt, Tom R TR; Groop, Leif L; Gudnason, Vilmundur V; Harris, Tamara B TB; Hayward, Caroline C; Hennig, Branwen J BJ; Herzig, Karl-Heinz KH; Ingelsson, Erik E; Tuomilehto, Jaakko J; Järvelin, Marjo-Riitta MR; Jukema, J Wouter JW; Kardia, Sharon L R SLR; Kee, Frank F; Kooner, Jaspal S JS; Kooperberg, Charles C; Launer, Lenore J LJ; Lind, Lars L; Loos, Ruth J F RJF; Majumder, Abdulla Al Shafi AAS; Laakso, Markku M; McCarthy, Mark I MI; Melander, Olle O; Mohlke, Karen L KL; Murray, Alison D AD; Nordestgaard, Børge Grønne BG; Orho-Melander, Marju M; Packard, Chris J CJ; Padmanabhan, Sandosh S; Palmas, Walter W; Polasek, Ozren O; Porteous, David J DJ; Prentice, Andrew M AM; Province, Michael A MA; Relton, Caroline L CL; Rice, Kenneth K; Ridker, Paul M PM; Rolandsson, Olov O; Rosendaal, Frits R FR; Rotter, Jerome I JI; Rudan, Igor I; Salomaa, Veikko V; Samani, Nilesh J NJ; Sattar, Naveed N; Sheu, Wayne H-H WH; Smith, Blair H BH; Soranzo, Nicole N; Spector, Timothy D TD; Starr, John M JM; Sebert, Sylvain S; Taylor, Kent D KD; Lakka, Timo A TA; Timpson, Nicholas J NJ; Tobin, Martin D MD; , ; van der Harst, Pim P; van der Meer, Peter P; Ramachandran, Vasan S VS; Verweij, Niek N; Virtamo, Jarmo J; Völker, Uwe U; Weir, David R DR; Zeggini, Eleftheria E; Charchar, Fadi J FJ; , ; Wareham, Nicholas J NJ; Langenberg, Claudia C; Tomaszewski, Maciej M; Butterworth, Adam S AS; Caulfield, Mark J MJ; Danesh, John J; Edwards, Todd L TL; Holm, Hilma H; Hung, Adriana M AM; Lindgren, Cecilia M CM; Liu, Chunyu C; Manning, Alisa K AK; Morris, Andrew P AP; Morrison, Alanna C AC; O'Donnell, Christopher J CJ; Psaty, Bruce M BM; Saleheen, Danish D; Stefansson, Kari K; Boerwinkle, Eric E; Chasman, Daniel I DI; Levy, Daniel D; Newton-Cheh, Christopher C; Munroe, Patricia B PB; Howson, Joanna M M JMM
Publication Date: 2020-12

Variant appearance in text: rs3918226
PubMed Link: 33230300
Variant Present in the following documents:
  • Main text
View BVdb publication page



Functionally informed fine-mapping and polygenic localization of complex trait heritability.

Nature Genetics
Weissbrod, Omer O; Hormozdiari, Farhad F; Benner, Christian C; Cui, Ran R; Ulirsch, Jacob J; Gazal, Steven S; Schoech, Armin P AP; van de Geijn, Bryce B; Reshef, Yakir Y; Márquez-Luna, Carla C; O'Connor, Luke L; Pirinen, Matti M; Finucane, Hilary K HK; Price, Alkes L AL
Publication Date: 2020-12

Variant appearance in text: rs3918226
PubMed Link: 33199916
Variant Present in the following documents:
  • Main text
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Genetic Variation in Cardiometabolic Traits and Medication Targets and the Risk of Hypertensive Disorders of Pregnancy.

Circulation
Honigberg, Michael C MC; Chaffin, Mark M; Aragam, Krishna K; Bhatt, Deepak L DL; Wood, Malissa J MJ; Sarma, Amy A AA; Scott, Nandita S NS; Peloso, Gina M GM; Natarajan, Pradeep P
Publication Date: 2020-08-18

Variant appearance in text: rs3918226
PubMed Link: 32804569
Variant Present in the following documents:
  • Main text
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Pharmacogenomics of Hypertension Treatment.

International Journal Of Molecular Sciences
Rysz, Jacek J; Franczyk, Beata B; Rysz-Górzyńska, Magdalena M; Gluba-Brzózka, Anna A
Publication Date: 2020-07-01

Variant appearance in text: rs3918226
PubMed Link: 32630286
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  • Main text
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The genetic risk for hypertension is lower among the Hungarian Roma population compared to the general population.

Plos One
Soltész, Beáta B; Pikó, Péter P; Sándor, János J; Kósa, Zsigmond Z; Ádány, Róza R; Fiatal, Szilvia S
Publication Date: 2020

Variant appearance in text: rs3918226
PubMed Link: 32555714
Variant Present in the following documents:
  • Main text
  • pone.0234547.pdf
  • pone.0234547.s001.pdf
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Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy.

Plos Genetics
Tekola-Ayele, Fasil F; Zhang, Cuilin C; Wu, Jing J; Grantz, Katherine L KL; Rahman, Mohammad L ML; Shrestha, Deepika D; Ouidir, Marion M; Workalemahu, Tsegaselassie T; Tsai, Michael Y MY
Publication Date: 2020-05

Variant appearance in text: rs3918226
PubMed Link: 32407400
Variant Present in the following documents:
  • Main text
  • pgen.1008747.pdf
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Genetic Factors of Nitric Oxide's System in Psychoneurologic Disorders.

International Journal Of Molecular Sciences
Nasyrova, Regina F RF; Moskaleva, Polina V PV; Vaiman, Elena E EE; Shnayder, Natalya A NA; Blatt, Nataliya L NL; Rizvanov, Albert A AA
Publication Date: 2020-02-26

Variant appearance in text: rs3918226
PubMed Link: 32111088
Variant Present in the following documents:
  • Main text
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Sarcopenia-related traits and coronary artery disease: a bi-directional Mendelian randomization study.

Aging
Liu, Hui-Min HM; Zhang, Qiang Q; Shen, Wen-Di WD; Li, Bo-Yang BY; Lv, Wan-Qiang WQ; Xiao, Hong-Mei HM; Deng, Hong-Wen HW
Publication Date: 2020-02-16

Variant appearance in text: rs3918226
PubMed Link: 32062614
Variant Present in the following documents:
  • Main text
  • aging-12-102815.pdf
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Precision Medicine and Cardiovascular Health: Insights from Mendelian Randomization Analyses.

Korean Circulation Journal
Spiller, Wes W; Jung, Keum Ji KJ; Lee, Ji Young JY; Jee, Sun Ha SH
Publication Date: 2020-02

Variant appearance in text: rs3918226
PubMed Link: 31845553
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  • Main text
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Pharmacogenomics And Hypertension: Current Insights.

Pharmacogenomics And Personalized Medicine
Oliveira-Paula, Gustavo H GH; Pereira, Sherliane C SC; Tanus-Santos, Jose E JE; Lacchini, Riccardo R
Publication Date: 2019

Variant appearance in text: rs3918226
PubMed Link: 31819590
Variant Present in the following documents:
  • Main text
  • pgpm-12-341.pdf
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Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema.

Human Molecular Genetics
Johansson, Åsa Å; Rask-Andersen, Mathias M; Karlsson, Torgny T; Ek, Weronica E WE
Publication Date: 2019-12-01

Variant appearance in text: rs3918226
PubMed Link: 31361310
Variant Present in the following documents:
  • Main text
  • ddz175.pdf
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Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects.

Circulation
Gill, Dipender D; Georgakis, Marios K MK; Koskeridis, Fotios F; Jiang, Lan L; Feng, Qiping Q; Wei, Wei-Qi WQ; Theodoratou, Evropi E; Elliott, Paul P; Denny, Joshua C JC; Malik, Rainer R; Evangelou, Evangelos E; Dehghan, Abbas A; Dichgans, Martin M; Tzoulaki, Ioanna I
Publication Date: 2019-07-23

Variant appearance in text: rs3918226
PubMed Link: 31234639
Variant Present in the following documents:
  • cir-140-270-s001.pdf
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Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases.

Pulse (Basel, Switzerland)
Wang, Yan Y; Wang, Ji-Guang JG
Publication Date: 2019-04

Variant appearance in text: rs3918226
PubMed Link: 31049317
Variant Present in the following documents:
  • Main text
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Sex-Specific Genetic Susceptibility to Adverse Neurodevelopmental Outcome in Offspring of Pregnancies at Risk of Early Preterm Delivery.

American Journal Of Perinatology
Varner, Michael W MW; Costantine, Maged M MM; Jablonski, Kathleen A KA; Rouse, Dwight J DJ; Mercer, Brian M BM; Leveno, Kenneth J KJ; Reddy, Uma M UM; Buhimschi, Catalin C; Wapner, Ronald J RJ; Sorokin, Yoram Y; Thorp, John M JM; Ramin, Susan M SM; Malone, Fergal D FD; Carpenter, Marshall M; O'sullivan, Mary J MJ; Peaceman, Alan M AM; Dudley, Donald J DJ; Caritis, Steve N SN; ,
Publication Date: 2020-02

Variant appearance in text: rs3918226
PubMed Link: 30731481
Variant Present in the following documents:
  • Main text
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Genome-wide meta-analysis identifies 3 novel loci associated with stroke.

Annals Of Neurology
Malik, Rainer R; Rannikmäe, Kristiina K; Traylor, Matthew M; Georgakis, Marios K MK; Sargurupremraj, Muralidharan M; Markus, Hugh S HS; Hopewell, Jemma C JC; Debette, Stephanie S; Sudlow, Cathie L M CLM; Dichgans, Martin M; ,
Publication Date: 2018-12

Variant appearance in text: rs3918226
PubMed Link: 30383316
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Hypertension and Cerebral Microangiopathy (Cerebral Small Vessel Disease): Genetic and Epigenetic Aspects of Their Relationship.

Acta Naturae
Dobrynina, L A LA; Zabitova, M R MR; Kalashnikova, L A LA; Gnedovskaya, E V EV; Piradov, M A MA
Publication Date: 2018

Variant appearance in text: rs3918226
PubMed Link: 30116610
Variant Present in the following documents:
  • Main text
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Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.

Nature Genetics
Zhou, Wei W; Nielsen, Jonas B JB; Fritsche, Lars G LG; Dey, Rounak R; Gabrielsen, Maiken E ME; Wolford, Brooke N BN; LeFaive, Jonathon J; VandeHaar, Peter P; Gagliano, Sarah A SA; Gifford, Aliya A; Bastarache, Lisa A LA; Wei, Wei-Qi WQ; Denny, Joshua C JC; Lin, Maoxuan M; Hveem, Kristian K; Kang, Hyun Min HM; Abecasis, Goncalo R GR; Willer, Cristen J CJ; Lee, Seunggeun S
Publication Date: 2018-09

Variant appearance in text: rs3918226
PubMed Link: 30104761
Variant Present in the following documents:
  • NIHMS977253-supplement-1.pdf
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GWAS Reveal Targets in Vessel Wall Pathways to Treat Coronary Artery Disease.

Frontiers In Cardiovascular Medicine
Turner, Adam W AW; Wong, Doris D; Dreisbach, Caitlin N CN; Miller, Clint L CL
Publication Date: 2018

Variant appearance in text: rs3918226
PubMed Link: 29988570
Variant Present in the following documents:
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Finding associated variants in genome-wide association studies on multiple traits.

Bioinformatics (Oxford, England)
Gai, Lisa L; Eskin, Eleazar E
Publication Date: 2018-07-01

Variant appearance in text: rs3918226
PubMed Link: 29949991
Variant Present in the following documents:
  • Main text
  • bty249.pdf
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Evaluation of 71 Coronary Artery Disease Risk Variants in a Multiethnic Cohort.

Frontiers In Cardiovascular Medicine
Ke, Wangjing W; Rand, Kristin A KA; Conti, David V DV; Setiawan, Veronica W VW; Stram, Daniel O DO; Wilkens, Lynne L; Le Marchand, Loic L; Assimes, Themistocles L TL; Haiman, Christopher A CA
Publication Date: 2018

Variant appearance in text: rs3918226
PubMed Link: 29740590
Variant Present in the following documents:
  • Main text
  • fcvm-05-00019.pdf
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Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.

Cardiovascular Diabetology
Charmet, Romain R; Duffy, Seamus S; Keshavarzi, Sareh S; Gyorgy, Beata B; Marre, Michel M; Rossing, Peter P; McKnight, Amy Jayne AJ; Maxwell, Alexander P AP; Ahluwalia, Tarun Veer Singh TVS; Paterson, Andrew D AD; Trégouët, David-Alexandre DA; Hadjadj, Samy S
Publication Date: 2018-04-25

Variant appearance in text: rs3918226
PubMed Link: 29695241
Variant Present in the following documents:
  • Main text
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Brief Overview of a Decade of Genome-Wide Association Studies on Primary Hypertension.

International Journal Of Endocrinology
Azam, Afifah Binti AB; Azizan, Elena Aisha Binti EAB
Publication Date: 2018

Variant appearance in text: rs3918226
PubMed Link: 29666641
Variant Present in the following documents:
  • Main text
  • IJE2018-7259704.pdf
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Targeted Nitric Oxide Synthase Inhibitors for Migraine.

Neurotherapeutics : The Journal Of The American Society For Experimental Neurotherapeutics
Pradhan, Amynah A AA; Bertels, Zachariah Z; Akerman, Simon S
Publication Date: 2018-04

Variant appearance in text: rs3918226
PubMed Link: 29516436
Variant Present in the following documents:
  • Main text
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Genetic Variation, Magnesium Sulfate Exposure, and Adverse Neurodevelopmental Outcomes Following Preterm Birth.

American Journal Of Perinatology
Clark, Erin A S EAS; Weiner, Steven J SJ; Rouse, Dwight J DJ; Mercer, Brian M BM; Reddy, Uma M UM; Iams, Jay D JD; Wapner, Ronald J RJ; Sorokin, Yoram Y; Malone, Fergal D FD; O'Sullivan, Mary J MJ; Peaceman, Alan M AM; Hankins, Gary D V GDV; Dudley, Donald J DJ; Caritis, Steve N SN; ,
Publication Date: 2018-08

Variant appearance in text: rs3918226
PubMed Link: 29510423
Variant Present in the following documents:
  • Main text
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Advances in the Genetics of Hypertension: The Effect of Rare Variants.

International Journal Of Molecular Sciences
Russo, Alessia A; Di Gaetano, Cornelia C; Cugliari, Giovanni G; Matullo, Giuseppe G
Publication Date: 2018-02-28

Variant appearance in text: rs3918226
PubMed Link: 29495593
Variant Present in the following documents:
  • Main text
  • ijms-19-00688.pdf
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Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.

Circulation Research
van der Harst, Pim P; Verweij, Niek N
Publication Date: 2018-02-02

Variant appearance in text: rs3918226
PubMed Link: 29212778
Variant Present in the following documents:
  • res-122-433.pdf
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Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling.

Circulation
Emdin, Connor A CA; Khera, Amit V AV; Klarin, Derek D; Natarajan, Pradeep P; Zekavat, Seyedeh M SM; Nomura, Akihiro A; Haas, Mary M; Aragam, Krishna K; Ardissino, Diego D; Wilson, James G JG; Schunkert, Heribert H; McPherson, Ruth R; Watkins, Hugh H; Elosua, Roberto R; Bown, Matthew J MJ; Samani, Nilesh J NJ; Baber, Usman U; Erdmann, Jeanette J; Gormley, Padhraig P; Palotie, Aarno A; Stitziel, Nathan O NO; Gupta, Namrata N; Danesh, John J; Saleheen, Danish D; Gabriel, Stacey S; Kathiresan, Sekar S
Publication Date: 2018-01-16

Variant appearance in text: rs3918226
PubMed Link: 28982690
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  • Main text
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Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans.

Physiological Reviews
Padmanabhan, Sandosh S; Joe, Bina B
Publication Date: 2017-10-01

Variant appearance in text: rs3918226
PubMed Link: 28931564
Variant Present in the following documents:
  • Main text
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Association of nitric oxide synthase 3 gene polymorphism with the risk of type 2 diabetes.

Biomedical Reports
Garme, Yasaman Y; Saravani, Ramin R; Galavi, Hamid Reza HR
Publication Date: 2017-07

Variant appearance in text: rs3918226
PubMed Link: 28685066
Variant Present in the following documents:
  • Main text
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Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.

Plos Genetics
Byars, Sean G SG; Huang, Qin Qin QQ; Gray, Lesley-Ann LA; Bakshi, Andrew A; Ripatti, Samuli S; Abraham, Gad G; Stearns, Stephen C SC; Inouye, Michael M
Publication Date: 2017-06

Variant appearance in text: rs3918226
PubMed Link: 28640878
Variant Present in the following documents:
  • pgen.1006328.s006.pdf
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