KMT2C c.11594_11595delinsTT ;(p.S3865F)

Variant ID: 7-151856023-TG-AA

NM_170606.2(KMT2C):c.11594_11595delinsTT;(p.S3865F)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Gain-of-Function Genetic Alterations of G9a Drive Oncogenesis.

Cancer Discovery
Kato, Shinichiro S; Weng, Qing Yu QY; Insco, Megan L ML; Chen, Kevin Y KY; Muralidhar, Sathya S; Pozniak, Joanna J; Diaz, Joey Mark S JMS; Drier, Yotam Y; Nguyen, Nhu N; Lo, Jennifer A JA; van Rooijen, Ellen E; Kemeny, Lajos V LV; Zhan, Yao Y; Feng, Yang Y; Silkworth, Whitney W; Powell, C Thomas CT; Liau, Brian B BB; Xiong, Yan Y; Jin, Jian J; Newton-Bishop, Julia J; Zon, Leonard I LI; Bernstein, Bradley E BE; Fisher, David E DE
Publication Date: 2020-07

Variant appearance in text: MLL3: S3865F
PubMed Link: 32269030
Variant Present in the following documents:
  • Main text
View BVdb publication page



Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex.

Molecular Oncology
Weirich, Sara S; Kudithipudi, Srikanth S; Jeltsch, Albert A
Publication Date: 2017-04

Variant appearance in text: MLL3: S3865F
PubMed Link: 28182322
Variant Present in the following documents:
  • Main text
  • MOL2-11-373.pdf
View BVdb publication page