Publications:

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A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER

Publication Date: 2023-03-16

Variant appearance in text: KMT2C: K339N

PubMed Link: 36928921

Variant Present in the following documents:

• ccr-22-3642_supplementary_tables_1_suppts1.xlsx, sheet 3

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Analysis of matched primary and recurrent BRCA1/2 mutation-associated tumors identifies recurrence-specific drivers.

Nature Communications

Shah, Jennifer B JB; Pueschl, Dana D; Wubbenhorst, Bradley B; Fan, Mengyao M; Pluta, John J; D'Andrea, Kurt K; Hubert, Anna P AP; Shilan, Jake S JS; Zhou, Wenting W; Kraya, Adam A AA; Llop Guevara, Alba A; Ruan, Catherine C; Serra, Violeta V; Balmaña, Judith J; Feldman, Michael M; Morin, Pat J PJ; Nayak, Anupma A; Maxwell, Kara N KN; Domchek, Susan M SM; Nathanson, Katherine L KL

Publication Date: 2022-11-07

Variant appearance in text: KMT2C: K339N

PubMed Link: 36344544

Variant Present in the following documents:

• 41467_2022_34523_MOESM4_ESM.xlsx, sheet 3
• 41467_2022_34523_MOESM4_ESM.xlsx, sheet 5

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Single-cell sequencing reveals CD133+CD44--originating evolution and novel stemness related variants in human colorectal cancer.

Ebiomedicine

Zhang, Xiaoyan X; Yang, Ling L; Lei, Wanjun W; Hou, Qiang Q; Huang, Ming M; Zhou, Rongjing R; Enver, Tariq T; Wu, Shixiu S

Publication Date: 2022-08

Variant appearance in text: KMT2C: K339N

PubMed Link: 35785618

Variant Present in the following documents:

• mmc1.xlsx, sheet 4
• mmc1.xlsx, sheet 2

View BVdb publication page

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Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity.

Nature Communications

Shi, Xiaohan X; Li, Yunguang Y; Yuan, Qiuyue Q; Tang, Shijie S; Guo, Shiwei S; Zhang, Yehan Y; He, Juan J; Zhang, Xiaoyu X; Han, Ming M; Liu, Zhuang Z; Zhu, Yiqin Y; Gao, Suizhi S; Wang, Huan H; Xu, Xiongfei X; Zheng, Kailian K; Jing, Wei W; Chen, Luonan L; Wang, Yong Y; Jin, Gang G; Gao, Dong D

Publication Date: 2022-04-21

Variant appearance in text: KMT2C: K339N

PubMed Link: 35449156

Variant Present in the following documents:

• 41467_2022_29857_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: KMT2C: 1017G>T; K339N

PubMed Link: 34887858

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

View BVdb publication page

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Comprehensive molecular analysis of genomic profiles and PD-L1 expression in lung adenocarcinoma with a high-grade fetal adenocarcinoma component.

Translational Lung Cancer Research

Suzuki, Masaki M; Kasajima, Rika R; Yokose, Tomoyuki T; Ito, Hiroyuki H; Shimizu, Eigo E; Hatakeyama, Seira S; Yokoyama, Kazuaki K; Yamaguchi, Rui R; Furukawa, Yoichi Y; Miyano, Satoru S; Imoto, Seiya S; Yoshioka, Emi E; Washimi, Kota K; Okubo, Yoichiro Y; Kawachi, Kae K; Sato, Shinya S; Miyagi, Yohei Y

Publication Date: 2021-03

Variant appearance in text: KMT2C: K339N

PubMed Link: 33889510

Variant Present in the following documents:

• tlcr-10-03-1292-supplementary.pdf

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Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma.

Scientific Reports

Pedrosa, Lucía L; Fernández-Miranda, Ismael I; Pérez-Callejo, David D; Quero, Cristina C; Rodríguez, Marta M; Martín-Acosta, Paloma P; Gómez, Sagrario S; González-Rincón, Julia J; Santos, Adrián A; Tarin, Carlos C; García, Juan F JF; García-Arroyo, Francisco R FR; Rueda, Antonio A; Camacho, Francisca I FI; García-Cosío, Mónica M; Heredero, Ana A; Llanos, Marta M; Mollejo, Manuela M; Piris-Villaespesa, Miguel M; Gómez-Codina, José J; Yanguas-Casás, Natalia N; Sánchez, Antonio A; Piris, Miguel A MA; Provencio, Mariano M; Sánchez-Beato, Margarita M

Publication Date: 2021-01-21

Variant appearance in text: KMT2C: K339N

PubMed Link: 33479306

Variant Present in the following documents:

• 41598_2020_80376_MOESM1_ESM.xlsx, sheet 3

View BVdb publication page

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UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin.

Plos Genetics

Saini, Natalie N; Giacobone, Camille K CK; Klimczak, Leszek J LJ; Papas, Brian N BN; Burkholder, Adam B AB; Li, Jian-Liang JL; Fargo, David C DC; Bai, Re R; Gerrish, Kevin K; Innes, Cynthia L CL; Schurman, Shepherd H SH; Gordenin, Dmitry A DA

Publication Date: 2021-01

Variant appearance in text: KMT2C: K339N

PubMed Link: 33444353

Variant Present in the following documents:

• pgen.1009302.s014.xlsx, sheet 1

View BVdb publication page

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Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer.

Cell Reports. Medicine

Roper, Nitin N; Brown, Anna-Leigh AL; Wei, Jun S JS; Pack, Svetlana S; Trindade, Christopher C; Kim, Chul C; Restifo, Olivia O; Gao, Shaojian S; Sindiri, Sivasish S; Mehrabadi, Farid F; El Meskini, Rajaa R; Ohler, Zoe Weaver ZW; Maity, Tapan K TK; Venugopalan, Abhilash A; Cultraro, Constance M CM; Akoth, Elizabeth E; Padiernos, Emerson E; Chen, Haobin H; Kesarwala, Aparna A; Smart, DeeDee K DK; Nilubol, Naris N; Rajan, Arun A; Piotrowska, Zofia Z; Xi, Liqiang L; Raffeld, Mark M; Panchenko, Anna R AR; Sahinalp, Cenk C; Hewitt, Stephen S; Hoang, Chuong D CD; Khan, Javed J; Guha, Udayan U

Publication Date: 2020-04-21

Variant appearance in text: KMT2C: K339N

PubMed Link: 32483558

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

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Interrogating Mutant Allele Expression via Customized Reference Genomes to Define Influential Cancer Mutations.

Scientific Reports

Grant, Adam D AD; Vail, Paris P; Padi, Megha M; Witkiewicz, Agnieszka K AK; Knudsen, Erik S ES

Publication Date: 2019-09-04

Variant appearance in text: KMT2C: K339N

PubMed Link: 31484939

Variant Present in the following documents:

• 41598_2019_48967_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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Difference of molecular alterations in HER2-positive and HER2-negative gastric cancers by whole-genome sequencing analysis.

Cancer Management And Research

Zhou, Chenfei C; Feng, Xiaojing X; Yuan, Fei F; Ji, Jun J; Shi, Min M; Yu, Yingyan Y; Zhu, Zhenggang Z; Zhang, Jun J

Publication Date: 2018

Variant appearance in text: KMT2C: K339N

PubMed Link: 30310315

Variant Present in the following documents:

• Main text
• cmar-10-3945.pdf

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Clinical significance of detecting CSF-derived tumor cells in breast cancer patients with leptomeningeal metastasis.

Oncotarget

Li, Xuelu X; Zhang, Yuan Y; Ding, Jinlei J; Wang, Min M; Li, Na N; Yang, Hui H; Wang, Kainan K; Wang, Dandan D; Lin, Peter Ping PP; Li, Man M; Zhao, Zuowei Z; Liu, Pixu P

Publication Date: 2018-01-05

Variant appearance in text: KMT2C: K339N

PubMed Link: 29416803

Variant Present in the following documents:

• oncotarget-09-2705-s003.xlsx, sheet 2

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Co-existence of BRAF and NRAS driver mutations in the same melanoma cells results in heterogeneity of targeted therapy resistance.

Oncotarget

Raaijmakers, Marieke I G MI; Widmer, Daniel S DS; Narechania, Apurva A; Eichhoff, Ossia O; Freiberger, Sandra N SN; Wenzina, Judith J; Cheng, Phil F PF; Mihic-Probst, Daniela D; Desalle, Rob R; Dummer, Reinhard R; Levesque, Mitchell P MP

Publication Date: 2016-11-22

Variant appearance in text: KMT2C: K339N

PubMed Link: 27791198

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

Fusco, Nicola N; Geyer, Felipe C FC; De Filippo, Maria R MR; Martelotto, Luciano G LG; Ng, Charlotte K Y CK; Piscuoglio, Salvatore S; Guerini-Rocco, Elena E; Schultheis, Anne M AM; Fuhrmann, Laetitia L; Wang, Lu L; Jungbluth, Achim A AA; Burke, Kathleen A KA; Lim, Raymond S RS; Vincent-Salomon, Anne A; Bamba, Masamichi M; Moritani, Suzuko S; Badve, Sunil S SS; Ichihara, Shu S; Ellis, Ian O IO; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2016-11

Variant appearance in text: KMT2C: K339N

PubMed Link: 27491809

Variant Present in the following documents:

• Main text
• nihms791815.pdf

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Colorectal Cancer Genetic Heterogeneity Delineated by Multi-Region Sequencing.

Plos One

Lu, You-Wang YW; Zhang, Hui-Feng HF; Liang, Rui R; Xie, Zhen-Rong ZR; Luo, Hua-You HY; Zeng, Yu-Jian YJ; Xu, Yu Y; Wang, La-Mei LM; Kong, Xiang-Yang XY; Wang, Kun-Hua KH

Publication Date: 2016

Variant appearance in text: KMT2C: K339N

PubMed Link: 27023146

Variant Present in the following documents:

• Main text
• pone.0152673.s002.xlsx, sheet 8
• pone.0152673.s002.xlsx, sheet 9
• pone.0152673.s002.xlsx, sheet 10
• pone.0152673.s002.xlsx, sheet 6
• pone.0152673.s002.xlsx, sheet 5
• pone.0152673.pdf
• pone.0152673.s002.xlsx, sheet 7

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