Fam20C regulates protein secretion by Cab45 phosphorylation.
The Journal Of Cell Biology
Hecht, Tobias Karl-Heinz TK; Blank, Birgit B; Steger, Martin M; Lopez, Victor V; Beck, Gisela G; Ramazanov, Bulat B; Mann, Matthias M; Tagliabracci, Vincent V; von Blume, Julia J
Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor).
Arteriosclerosis, Thrombosis, And Vascular Biology
Ben Djoudi Ouadda, Ali A; Gauthier, Marie-Soleil MS; Susan-Resiga, Delia D; Girard, Emmanuelle E; Essalmani, Rachid R; Black, Miles M; Marcinkiewicz, Jadwiga J; Forget, Diane D; Hamelin, Josée J; Evagelidis, Alexandra A; Ly, Kevin K; Day, Robert R; Galarneau, Luc L; Corbin, Francois F; Coulombe, Benoit B; Çaku, Artuela A; Tagliabracci, Vincent S VS; Seidah, Nabil G NG
In vitro phosphorylation of von Willebrand factor by FAM20c enhances its ability to support platelet adhesion.
Journal Of Thrombosis And Haemostasis : Jth
Da, Qi Q; Han, Hyojeong H; Valladolid, Christian C; Fernández, María M; Khatlani, Tanvir T; Pradhan, Subhashree S; Nolasco, Jennifer J; Matsunami, Risë K RK; Engler, David A DA; Cruz, Miguel A MA; Vijayan, K Vinod KV
A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure.
Elife
Pollak, Adam J AJ; Liu, Canzhao C; Gudlur, Aparna A; Mayfield, Joshua E JE; Dalton, Nancy D ND; Gu, Yusu Y; Chen, Ju J; Heller Brown, Joan J; Hogan, Patrick G PG; Wiley, Sandra E SE; Peterson, Kirk L KL; Dixon, Jack E JE
A Single Kinase Generates the Majority of the Secreted Phosphoproteome.
Cell
Tagliabracci, Vincent S VS; Wiley, Sandra E SE; Guo, Xiao X; Kinch, Lisa N LN; Durrant, Eric E; Wen, Jianzhong J; Xiao, Junyu J; Cui, Jixin J; Nguyen, Kim B KB; Engel, James L JL; Coon, Joshua J JJ; Grishin, Nick N; Pinna, Lorenzo A LA; Pagliarini, David J DJ; Dixon, Jack E JE
Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Tagliabracci, Vincent S VS; Engel, James L JL; Wiley, Sandra E SE; Xiao, Junyu J; Gonzalez, David J DJ; Nidumanda Appaiah, Hitesh H; Koller, Antonius A; Nizet, Victor V; White, Kenneth E KE; Dixon, Jack E JE