AURKA, TOP2A and MELK are the key genes identified by WGCNA for the pathogenesis of lung adenocarcinoma.
Oncology Letters
Xu, Yunqing Y; Wang, Sen S; Xu, Bin B; Lin, Huiqing H; Zhan, Na N; Ren, Jiacai J; Song, Wenling W; Han, Rong R; Cheng, Liping L; Zhang, Man M; Zhang, Xiuyun X
Tumor cell SYK expression modulates the tumor immune microenvironment composition in human cancer via TNF-α dependent signaling.
Journal For Immunotherapy Of Cancer
Aguirre-Ducler, Adam A; Gianino, Nicole N; Villarroel-Espindola, Franz F; Desai, Shruti S; Tang, Daiwei D; Zhao, Hongyu H; Syrigos, Konstantinos K; Trepicchio, William L WL; Kannan, Karuppiah K; Gregory, Richard C RC; Schalper, Kurt A KA
Structural, mechanistic, and physiological insights into phospholipase A-mediated membrane phospholipid degradation in Pseudomonas aeruginosa.
Elife
Bleffert, Florian F; Granzin, Joachim J; Caliskan, Muttalip M; Schott-Verdugo, Stephan N SN; Siebers, Meike M; Thiele, Björn B; Rahme, Laurence L; Felgner, Sebastian S; Dörmann, Peter P; Gohlke, Holger H; Batra-Safferling, Renu R; Jaeger, Karl-Erich KE; Kovacic, Filip F
Cost-Effectiveness Analysis of Gefitinib Alone and Combined with Chemotherapy as First-Line Treatment for Patients with Advanced Non-Small-Cell Lung Cancer.
Risk Management And Healthcare Policy
Wang, Yao Y; Huang, Kaiyu K; Sun, Sijia S; Deng, Yahong Y; Xie, Xuefeng X
Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis.
Plos Medicine
Yarmolinsky, James J; Díez-Obrero, Virginia V; Richardson, Tom G TG; Pigeyre, Marie M; Sjaarda, Jennifer J; Paré, Guillaume G; Walker, Venexia M VM; Vincent, Emma E EE; Tan, Vanessa Y VY; Obón-Santacana, Mireia M; Albanes, Demetrius D; Hampe, Jochen J; Gsur, Andrea A; Hampel, Heather H; Pai, Rish K RK; Jenkins, Mark M; Gallinger, Steven S; Casey, Graham G; Zheng, Wei W; Amos, Christopher I CI; , ; , ; , ; Smith, George Davey GD; Martin, Richard M RM; Moreno, Victor V
Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis.
Plos Medicine
Yarmolinsky, James J; Díez-Obrero, Virginia V; Richardson, Tom G TG; Pigeyre, Marie M; Sjaarda, Jennifer J; Paré, Guillaume G; Walker, Venexia M VM; Vincent, Emma E EE; Tan, Vanessa Y VY; Obón-Santacana, Mireia M; Albanes, Demetrius D; Hampe, Jochen J; Gsur, Andrea A; Hampel, Heather H; Pai, Rish K RK; Jenkins, Mark M; Gallinger, Steven S; Casey, Graham G; Zheng, Wei W; Amos, Christopher I CI; , ; , ; , ; Smith, George Davey GD; Martin, Richard M RM; Moreno, Victor V
Repeated centralized multidisciplinary team assessment of resectability, clinical behavior, and outcomes in 1086 Finnish metastatic colorectal cancer patients (RAXO): A nationwide prospective intervention study.
The Lancet Regional Health. Europe
Osterlund, Pia P; Salminen, Tapio T; Soveri, Leena-Maija LM; Kallio, Raija R; Kellokumpu, Ilmo I; Lamminmäki, Annamarja A; Halonen, Päivi P; Ristamäki, Raija R; Lantto, Eila E; Uutela, Aki A; Osterlund, Emerik E; Ovissi, Ali A; Nordin, Arno A; Heervä, Eetu E; Lehtomäki, Kaisa K; Räsänen, Jari J; Murashev, Maija M; Aroviita, Laura L; Jekunen, Antti A; Lindvall-Andersson, Reneé R; Nyandoto, Paul P; Kononen, Juha J; Lepistö, Anna A; Poussa, Tuija T; Muhonen, Timo T; Ålgars, Annika A; Isoniemi, Helena H; ,
Non-invasive measurement of PD-L1 status and prediction of immunotherapy response using deep learning of PET/CT images.
Journal For Immunotherapy Of Cancer
Mu, Wei W; Jiang, Lei L; Shi, Yu Y; Tunali, Ilke I; Gray, Jhanelle E JE; Katsoulakis, Evangelia E; Tian, Jie J; Gillies, Robert J RJ; Schabath, Matthew B MB
Role of combining neutrophil-to-lymphocyte ratio and pretreatment body mass index in predicting progression-free survival in patients with non-small cell lung cancer treated with nivolumab.
Experimental And Therapeutic Medicine
Dragomir, Radu R; Dragomir, Adelina Silvana AS; Negru, Alina A; Săftescu, Sorin S; Popovici, Dorel D; Schenker, Michael M; Lupușoru, Raluca R; Negru, Șerban Ș
The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent.
Scientific Reports
Cheng, Yinwen Y; Borcherding, Nicholas N; Ogunsakin, Ayomide A; Lemke-Miltner, Caitlin D CD; Gibson-Corley, Katherine N KN; Rajan, Anand A; Choi, Allen B AB; Wongpattaraworakul, Wattawan W; Chan, Carlos H F CHF; Salem, Aliasger K AK; Weiner, George J GJ; Simons, Andrean L AL
Cost-effectiveness analysis of cetuximab combined with chemotherapy as a first-line treatment for patients with RAS wild-type metastatic colorectal cancer based on the TAILOR trial.
Bmj Open
Wang, Huijuan H; Huang, Lingfei L; Gao, Peng P; Zhu, Zhengyi Z; Ye, Weifeng W; Ding, Haiying H; Fang, Luo L
lncRNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 Promotes Proliferation and Invasion of Non-Small Cell Lung Cancer Cells via Down-Regulating miR-202 Expression.
Cell Journal
Tiansheng, Guo G; Junming, Huang H; Xiaoyun, Wan W; Peixi, Chen C; Shaoshan, Du D; Qianping, Chen C
Proceedings of the 57th Annual Meeting of the Particle Therapy Cooperative Group (PTCOG): 21-26 May 2018, Hosted by Cincinnati Children's and the University of Cincinnati, part of the Cincinnati Cancer Center, Cincinnati, Ohio, USA.
34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019): part 2 : National Harbor, MD, USA. 10 November 2019.
Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy.
Nature Communications
Caswell-Jin, Jennifer L JL; McNamara, Katherine K; Reiter, Johannes G JG; Sun, Ruping R; Hu, Zheng Z; Ma, Zhicheng Z; Ding, Jie J; Suarez, Carlos J CJ; Tilk, Susanne S; Raghavendra, Akshara A; Forte, Victoria V; Chin, Suet-Feung SF; Bardwell, Helen H; Provenzano, Elena E; Caldas, Carlos C; Lang, Julie J; West, Robert R; Tripathy, Debu D; Press, Michael F MF; Curtis, Christina C
Advantage of Next-Generation Sequencing in Dynamic Monitoring of Circulating Tumor DNA over Droplet Digital PCR in Cetuximab Treated Colorectal Cancer Patients.
Translational Oncology
Zhang, Hangyu H; Liu, Rujiao R; Yan, Cong C; Liu, Lulu L; Tong, Zhou Z; Jiang, Weiqin W; Yao, Ming M; Fang, Weijia W; Chen, Zhiyu Z
Data-Independent Acquisition Mass Spectrometry To Quantify Protein Levels in FFPE Tumor Biopsies for Molecular Diagnostics.
Journal Of Proteome Research
Kim, Yeoun Jin YJ; Sweet, Steve M M SMM; Egertson, Jarrett D JD; Sedgewick, Andrew J AJ; Woo, Sunghee S; Liao, Wei-Li WL; Merrihew, Gennifer E GE; Searle, Brian C BC; Vaske, Charlie C; Heaton, Robert R; MacCoss, Michael J MJ; Hembrough, Todd T
Multiplex Cell-Free DNA Reference Materials for Quality Control of Next-Generation Sequencing-Based In Vitro Diagnostic Tests of Colorectal Cancer Tolerance.
Journal Of Cancer
Liu, Donglai D; Zhang, Xinyuan X; Zhou, Haiwei H; Lin, Xiaojing X; Shi, Dawei D; Shen, Shu S; Tian, Yabin Y; Du, Bo B; Zhang, Henghui H; Wang, Haibo H; Wang, Youchun Y; Zhang, Chuntao C
Immunoregulatory protein B7-H3 regulates cancer stem cell enrichment and drug resistance through MVP-mediated MEK activation.
Oncogene
Liu, Zixing Z; Zhang, Wenling W; Phillips, Joshua B JB; Arora, Ritu R; McClellan, Steven S; Li, Jiangfeng J; Kim, Jin-Hwan JH; Sobol, Robert W RW; Tan, Ming M
Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.
The Lancet. Gastroenterology & Hepatology
Domingo, Enric E; Camps, Carme C; Kaisaki, Pamela J PJ; Parsons, Marie J MJ; Mouradov, Dmitri D; Pentony, Melissa M MM; Makino, Seiko S; Palmieri, Michelle M; Ward, Robyn L RL; Hawkins, Nicholas J NJ; Gibbs, Peter P; Askautrud, Hanne H; Oukrif, Dahmane D; Wang, Haitao H; Wood, Joe J; Tomlinson, Evie E; Bark, Yasmine Y; Kaur, Kulvinder K; Johnstone, Elaine C EC; Palles, Claire C; Church, David N DN; Novelli, Marco M; Danielsen, Havard E HE; Sherlock, Jon J; Kerr, David D; Kerr, Rachel R; Sieber, Oliver O; Taylor, Jenny C JC; Tomlinson, Ian I
Low expression of G protein-coupled oestrogen receptor 1 (GPER) is associated with adverse survival of breast cancer patients.
Oncotarget
Martin, Stewart G SG; Lebot, Marie N MN; Sukkarn, Bhudsaban B; Ball, Graham G; Green, Andrew R AR; Rakha, Emad A EA; Ellis, Ian O IO; Storr, Sarah J SJ
Aberrant expression of miR-21, miR-376c and miR-145 and their target host genes in Merkel cell polyomavirus-positive non-small cell lung cancer.
Oncotarget
Lasithiotaki, Ismini I; Tsitoura, Eliza E; Koutsopoulos, Anastasios A; Lagoudaki, Eleni E; Koutoulaki, Chara C; Pitsidianakis, George G; Spandidos, Demetrios A DA; Siafakas, Nikolaos M NM; Sourvinos, George G; Antoniou, Katerina M KM
The relevance of prelamin A and RAD51 as molecular biomarkers in cervical cancer.
Oncotarget
Leonardi, Simona S; Buttarelli, Marianna M; De Stefano, Ilaria I; Ferrandina, Gabriella G; Petrillo, Marco M; Babini, Gabriele G; Scambia, Giovanni G; Marino, Carmela C; Mancuso, Mariateresa M; Gallo, Daniela D
Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.
Nature Medicine
Zehir, Ahmet A; Benayed, Ryma R; Shah, Ronak H RH; Syed, Aijazuddin A; Middha, Sumit S; Kim, Hyunjae R HR; Srinivasan, Preethi P; Gao, Jianjiong J; Chakravarty, Debyani D; Devlin, Sean M SM; Hellmann, Matthew D MD; Barron, David A DA; Schram, Alison M AM; Hameed, Meera M; Dogan, Snjezana S; Ross, Dara S DS; Hechtman, Jaclyn F JF; DeLair, Deborah F DF; Yao, JinJuan J; Mandelker, Diana L DL; Cheng, Donavan T DT; Chandramohan, Raghu R; Mohanty, Abhinita S AS; Ptashkin, Ryan N RN; Jayakumaran, Gowtham G; Prasad, Meera M; Syed, Mustafa H MH; Rema, Anoop Balakrishnan AB; Liu, Zhen Y ZY; Nafa, Khedoudja K; Borsu, Laetitia L; Sadowska, Justyna J; Casanova, Jacklyn J; Bacares, Ruben R; Kiecka, Iwona J IJ; Razumova, Anna A; Son, Julie B JB; Stewart, Lisa L; Baldi, Tessara T; Mullaney, Kerry A KA; Al-Ahmadie, Hikmat H; Vakiani, Efsevia E; Abeshouse, Adam A AA; Penson, Alexander V AV; Jonsson, Philip P; Camacho, Niedzica N; Chang, Matthew T MT; Won, Helen H HH; Gross, Benjamin E BE; Kundra, Ritika R; Heins, Zachary J ZJ; Chen, Hsiao-Wei HW; Phillips, Sarah S; Zhang, Hongxin H; Wang, Jiaojiao J; Ochoa, Angelica A; Wills, Jonathan J; Eubank, Michael M; Thomas, Stacy B SB; Gardos, Stuart M SM; Reales, Dalicia N DN; Galle, Jesse J; Durany, Robert R; Cambria, Roy R; Abida, Wassim W; Cercek, Andrea A; Feldman, Darren R DR; Gounder, Mrinal M MM; Hakimi, A Ari AA; Harding, James J JJ; Iyer, Gopa G; Janjigian, Yelena Y YY; Jordan, Emmet J EJ; Kelly, Ciara M CM; Lowery, Maeve A MA; Morris, Luc G T LGT; Omuro, Antonio M AM; Raj, Nitya N; Razavi, Pedram P; Shoushtari, Alexander N AN; Shukla, Neerav N; Soumerai, Tara E TE; Varghese, Anna M AM; Yaeger, Rona R; Coleman, Jonathan J; Bochner, Bernard B; Riely, Gregory J GJ; Saltz, Leonard B LB; Scher, Howard I HI; Sabbatini, Paul J PJ; Robson, Mark E ME; Klimstra, David S DS; Taylor, Barry S BS; Baselga, Jose J; Schultz, Nikolaus N; Hyman, David M DM; Arcila, Maria E ME; Solit, David B DB; Ladanyi, Marc M; Berger, Michael F MF
Prognostic Influence of BCL2 on Molecular Subtypes of Breast Cancer.
Journal Of Breast Cancer
Hwang, Ki-Tae KT; Han, Wonshik W; Kim, Jongjin J; Moon, Hyeong-Gon HG; Oh, Sohee S; Song, Yun Seon YS; Kim, Young A YA; Chang, Mee Soo MS; Noh, Dong-Young DY
Breast cancer in neurofibromatosis type 1: overrepresentation of unfavourable prognostic factors.
British Journal Of Cancer
Uusitalo, Elina E; Kallionpää, Roope A RA; Kurki, Samu S; Rantanen, Matti M; Pitkäniemi, Janne J; Kronqvist, Pauliina P; Härkönen, Pirkko P; Huovinen, Riikka R; Carpen, Olli O; Pöyhönen, Minna M; Peltonen, Sirkku S; Peltonen, Juha J
Helicobacter pylori-induced cell death is counteracted by NF-κB-mediated transcription of DARPP-32.
Gut
Zhu, Shoumin S; Soutto, Mohammed M; Chen, Zheng Z; Peng, DunFa D; Romero-Gallo, Judith J; Krishna, Uma S US; Belkhiri, Abbes A; Washington, M Kay MK; Peek, Richard R; El-Rifai, Wael W
MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis.
Science Signaling
Cataisson, Christophe C; Michalowski, Aleksandra M AM; Shibuya, Kelly K; Ryscavage, Andrew A; Klosterman, Mary M; Wright, Lisa L; Dubois, Wendy W; Liu, Fan F; Zhuang, Anne A; Rodrigues, Kameron B KB; Hoover, Shelley S; Dwyer, Jennifer J; Simpson, Mark R MR; Merlino, Glenn G; Yuspa, Stuart H SH
Expression of breast cancer stem cell markers as predictors of prognosis and response to trastuzumab in HER2-positive breast cancer.
British Journal Of Cancer
Seo, An Na AN; Lee, Hee Jin HJ; Kim, Eun Joo EJ; Jang, Min Hye MH; Kim, Yu Jung YJ; Kim, Jee Hyun JH; Kim, Sung-Won SW; Ryu, Han Suk HS; Park, In Ae IA; Im, Seock-Ah SA; Gong, Gyungyub G; Jung, Kyung Hae KH; Kim, Hee Jeong HJ; Park, So Yeon SY
Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases.
Elife
Jadwin, Joshua A JA; Oh, Dongmyung D; Curran, Timothy G TG; Ogiue-Ikeda, Mari M; Jia, Lin L; White, Forest M FM; Machida, Kazuya K; Yu, Ji J; Mayer, Bruce J BJ
High EZH2 Protein Expression Is Associated with Poor Overall Survival in Patients with Luminal A Breast Cancer.
Journal Of Breast Cancer
Jang, Si-Hyong SH; Lee, Jong Eun JE; Oh, Mee-Hye MH; Lee, Ji-Hye JH; Cho, Hyun Deuk HD; Kim, Kyung-Ju KJ; Kim, Sung Yong SY; Han, Sun Wook SW; Kim, Han Jo HJ; Bae, Sang Byung SB; Lee, Hyun Ju HJ
MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours.
British Journal Of Cancer
Green, Andrew R AR; Aleskandarany, Mohammed A MA; Agarwal, Devika D; Elsheikh, Somaia S; Nolan, Christopher C CC; Diez-Rodriguez, Maria M; Macmillan, R Douglas RD; Ball, Graham R GR; Caldas, Carlos C; Madhusudan, Srinivasan S; Ellis, Ian O IO; Rakha, Emad A EA
Loss of Tumor Suppressor ARID1A Protein Expression Correlates with Poor Prognosis in Patients with Primary Breast Cancer.
Journal Of Breast Cancer
Cho, Hyun Deuk HD; Lee, Jong Eun JE; Jung, Hae Yoen HY; Oh, Mee-Hye MH; Lee, Ji-Hye JH; Jang, Si-Hyong SH; Kim, Kyung-Ju KJ; Han, Sun Wook SW; Kim, Sung Yong SY; Kim, Han Jo HJ; Bae, Sang Byung SB; Lee, Hyun Ju HJ