EGFR c.136G>T ;(p.D46Y)

Variant ID: 7-55210026-G-T

NM_005228.3(EGFR):c.136G>T;(p.D46Y)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Genetic landscape and personalized tracking of tumor mutations in Vietnamese women with breast cancer.

Molecular Oncology
Nguyen Hoang, Van-Anh VA; Nguyen, Sao Trung ST; Nguyen, Trieu Vu TV; Pham, Thanh Huyen TH; Doan, Phuoc Loc PL; Nguyen Thi, Ngoc Thanh NT; Nguyen, Minh Long ML; Dinh, Thi Cuc TC; Pham, Dinh Hoang DH; Nguyen, Ngoc Mai NM; Nguyen, Duy Sinh DS; Nguyen, Du Quyen DQ; Lu, Y-Thanh YT; Do, Thanh Thuy Thi TTT; Truong, Dinh Kiet DK; Phan, Minh-Duy MD; Nguyen, Hoai-Nghia HN; Giang, Hoa H; Tu, Lan N LN
Publication Date: 2022-12-10

Variant appearance in text: EGFR: D46Y
PubMed Link: 36495126
Variant Present in the following documents:
  • MOL2-17-598-s002.xlsx, sheet 1
View BVdb publication page



Exploring Predictors of Response to Dacomitinib in EGFR-Amplified Recurrent Glioblastoma.

Jco Precision Oncology
Chi, Andrew S AS; Cahill, Daniel P DP; Reardon, David A DA; Wen, Patrick Y PY; Mikkelsen, Tom T; Peereboom, David M DM; Wong, Eric T ET; Gerstner, Elizabeth R ER; Dietrich, Jorg J; Plotkin, Scott R SR; Norden, Andrew D AD; Lee, Eudocia Q EQ; Nayak, Lakshmi L; Tanaka, Shota S; Wakimoto, Hiroaki H; Lelic, Nina N; Koerner, Mara V MV; Klofas, Lindsay K LK; Bertalan, Mia S MS; Arrillaga-Romany, Isabel C IC; Betensky, Rebecca A RA; Curry, William T WT; Borger, Darrel R DR; Balaj, Leonora L; Kitchen, Robert R RR; Chakrabortty, Sudipto K SK; Valentino, Michael D MD; Skog, Johan J; Breakefield, Xandra O XO; Iafrate, A John AJ; Batchelor, Tracy T TT
Publication Date: 2020

Variant appearance in text: EGFR: D46Y
PubMed Link: 32923886
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular profiling-based decision for targeted therapies in IDH wild-type glioblastoma.

Neuro-Oncology Advances
Kessler, Tobias T; Berberich, Anne A; Casalini, Belen B; Drüschler, Katharina K; Ostermann, Hannah H; Dormann, Andrea A; Walter, Sandy S; Hai, Ling L; Schlesner, Matthias M; Herold-Mende, Christel C; Jungk, Christine C; Unterberg, Andreas A; Bendszus, Martin M; Sahm, Katharina K; von Deimling, Andreas A; Winkler, Frank F; Platten, Michael M; Wick, Wolfgang W; Sahm, Felix F; Wick, Antje A
Publication Date: 2020

Variant appearance in text: EGFR: D46Y
PubMed Link: 32642725
Variant Present in the following documents:
  • vdz060_suppl_supplementary-table-s3.xlsx, sheet 1
View BVdb publication page



Phase and context shape the function of composite oncogenic mutations.

Nature
Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS
Publication Date: 2020-06

Variant appearance in text: EGFR: D46Y
PubMed Link: 32461694
Variant Present in the following documents:
  • NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2
View BVdb publication page



Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid.

Nature
Miller, Alexandra M AM; Shah, Ronak H RH; Pentsova, Elena I EI; Pourmaleki, Maryam M; Briggs, Samuel S; Distefano, Natalie N; Zheng, Youyun Y; Skakodub, Anna A; Mehta, Smrutiben A SA; Campos, Carl C; Hsieh, Wan-Ying WY; Selcuklu, S Duygu SD; Ling, Lilan L; Meng, Fanli F; Jing, Xiaohong X; Samoila, Aliaksandra A; Bale, Tejus A TA; Tsui, Dana W Y DWY; Grommes, Christian C; Viale, Agnes A; Souweidane, Mark M MM; Tabar, Viviane V; Brennan, Cameron W CW; Reiner, Anne S AS; Rosenblum, Marc M; Panageas, Katherine S KS; DeAngelis, Lisa M LM; Young, Robert J RJ; Berger, Michael F MF; Mellinghoff, Ingo K IK
Publication Date: 2019-01

Variant appearance in text: EGFR: 136G>T; D46Y
PubMed Link: 30675060
Variant Present in the following documents:
  • NIHMS1516901-supplement-Sup_Table_5.xlsx, sheet 1
View BVdb publication page



Multi-platform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies.

Oncotarget
Xiu, Joanne J; Piccioni, David D; Juarez, Tiffany T; Pingle, Sandeep C SC; Hu, Jethro J; Rudnick, Jeremy J; Fink, Karen K; Spetzler, David B DB; Maney, Todd T; Ghazalpour, Anatole A; Bender, Ryan R; Gatalica, Zoran Z; Reddy, Sandeep S; Sanai, Nader N; Idbaih, Ahmed A; Glantz, Michael M; Kesari, Santosh S
Publication Date: 2016-04-19

Variant appearance in text: EGFR: D46Y
PubMed Link: 26933808
Variant Present in the following documents:
  • oncotarget-07-21556-s001.pdf
View BVdb publication page