Publications:

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: EGFR: R108K

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 4
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 2
• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3

View BVdb publication page

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Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.

Nature Medicine

Sturm, Dominik D; Capper, David D; Andreiuolo, Felipe F; Gessi, Marco M; Kölsche, Christian C; Reinhardt, Annekathrin A; Sievers, Philipp P; Wefers, Annika K AK; Ebrahimi, Azadeh A; Suwala, Abigail K AK; Gielen, Gerrit H GH; Sill, Martin M; Schrimpf, Daniel D; Stichel, Damian D; Hovestadt, Volker V; Daenekas, Bjarne B; Rode, Agata A; Hamelmann, Stefan S; Previti, Christopher C; Jäger, Natalie N; Buchhalter, Ivo I; Blattner-Johnson, Mirjam M; Jones, Barbara C BC; Warmuth-Metz, Monika M; Bison, Brigitte B; Grund, Kerstin K; Sutter, Christian C; Hirsch, Steffen S; Dikow, Nicola N; Hasselblatt, Martin M; Schüller, Ulrich U; Gerber, Nicolas U NU; White, Christine L CL; Buntine, Molly K MK; Kinross, Kathryn K; Algar, Elizabeth M EM; Hansford, Jordan R JR; Gottardo, Nicholas G NG; Hernáiz Driever, Pablo P; Gnekow, Astrid A; Witt, Olaf O; Müller, Hermann L HL; Calaminus, Gabriele G; Fleischhack, Gudrun G; Kordes, Uwe U; Mynarek, Martin M; Rutkowski, Stefan S; Frühwald, Michael C MC; Kramm, Christof M CM; von Deimling, Andreas A; Pietsch, Torsten T; Sahm, Felix F; Pfister, Stefan M SM; Jones, David T W DTW

Publication Date: 2023-03-16

Variant appearance in text: EGFR: R108K

PubMed Link: 36928815

Variant Present in the following documents:

• 41591_2023_2255_MOESM3_ESM.xlsx, sheet 5

View BVdb publication page

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Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma.

Genome Medicine

Nam, Yoonhee Y; Koo, Harim H; Yang, Yingxi Y; Shin, Sang S; Zhu, Zhihan Z; Kim, Donggeon D; Cho, Hee Jin HJ; Mu, Quanhua Q; Choi, Seung Won SW; Sa, Jason K JK; Seo, Yun Jee YJ; Kim, Yejin Y; Lee, Kyoungmin K; Oh, Jeong-Woo JW; Kwon, Yong-Jun YJ; Park, Woong-Yang WY; Kong, Doo-Sik DS; Seol, Ho Jun HJ; Lee, Jung-Il JI; Park, Chul-Kee CK; Lee, Hye Won HW; Yoon, Yeup Y; Wang, Jiguang J

Publication Date: 2023-03-13

Variant appearance in text: EGFR: R108K

PubMed Link: 36915208

Variant Present in the following documents:

• 13073_2023_1165_MOESM1_ESM.xlsx, sheet 2

View BVdb publication page

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Genomics-Driven Precision Medicine in Pediatric Solid Tumors.

Cancers

Suthapot, Praewa P; Chiangjong, Wararat W; Chaiyawat, Parunya P; Choochuen, Pongsakorn P; Pruksakorn, Dumnoensun D; Sangkhathat, Surasak S; Hongeng, Suradej S; Anurathapan, Usanarat U; Chutipongtanate, Somchai S

Publication Date: 2023-02-23

Variant appearance in text: EGFR: R108K

PubMed Link: 36900212

Variant Present in the following documents:

• Main text
• cancers-15-01418.pdf

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: EGFR: 323G>A; Arg108Lys

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Application of the CDK9 inhibitor FIT-039 for the treatment of KSHV-associated malignancy.

Bmc Cancer

Sakamoto, Tetsunori T; Ajiro, Masahiko M; Watanabe, Akira A; Matsushima, Shingo S; Ueda, Keiji K; Hagiwara, Masatoshi M

Publication Date: 2023-01-20

Variant appearance in text: EGFR: R108K

PubMed Link: 36670405

Variant Present in the following documents:

• Main text
• 12885_2023_Article_10540.pdf

View BVdb publication page

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Pan-cancer molecular analysis of EGFR large fragment deletion in the Asian population.

Cancer Medicine

Pu, Jun J; Guo, Huannan H; Yu, Ruoying R; Ou, Qiuxiang Q; Bao, Hua H; Wu, Xue X; Tang, Sanyuan S; Chang, Qingyong Q

Publication Date: 2023-01-09

Variant appearance in text: EGFR: 323G>A; R108K

PubMed Link: 36622089

Variant Present in the following documents:

• CAM4-12-8083-s003.xlsx, sheet 1

View BVdb publication page

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Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan.

Cancer Science

Kage, Hidenori H; Shinozaki-Ushiku, Aya A; Ishigaki, Kazunaga K; Sato, Yusuke Y; Tanabe, Masahiko M; Tanaka, Shota S; Tanikawa, Michihiro M; Watanabe, Kousuke K; Kato, Shingo S; Akagi, Kiwamu K; Uchino, Keita K; Mitani, Kinuko K; Takahashi, Shunji S; Miura, Yuji Y; Ikeda, Sadakatsu S; Kojima, Yasushi Y; Watanabe, Kiyotaka K; Mochizuki, Hitoshi H; Yamaguchi, Hironori H; Kawazoe, Yoshimasa Y; Kashiwabara, Kosuke K; Kohsaka, Shinji S; Tatsuno, Kenji K; Ushiku, Tetsuo T; Ohe, Kazuhiko K; Yatomi, Yutaka Y; Seto, Yasuyuki Y; Aburatani, Hiroyuki H; Mano, Hiroyuki H; Miyagawa, Kiyoshi K; Oda, Katsutoshi K

Publication Date: 2023-01-05

Variant appearance in text: EGFR: 323G>A; R108K

PubMed Link: 36601953

Variant Present in the following documents:

• CAS-114-1710-s001.xlsx, sheet 1

View BVdb publication page

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Impact of EGFRA289T/V mutation on relapse pattern in glioblastoma.

Esmo Open

Noeuveglise, A A; Sarafan-Vasseur, N N; Beaussire, L L; Marguet, F F; Modzelewski, R R; Hanzen, C C; Alexandru, C C; Magne, N N; Langlois, O O; Di Fiore, F F; Clatot, F F; Thureau, S S; Fontanilles, M M

Publication Date: 2022-12-22

Variant appearance in text: EGFR: R108K

PubMed Link: 36566697

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs1057519828

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 4

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: EGFR: R108K

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Genomic landscape of lung cancer in the young.

Frontiers In Oncology

Ruiz, Rossana R; Galvez-Nino, Marco M; Roque, Katia K; Montes, Jaime J; Nuñez, Maria M; Raez, Luis L; Sánchez-Gambetta, Sergio S; Jaúregui, Sandra S; Viale, Sandra S; Smith, Edward S ES; Pinto, Joseph A JA; Mas, Luis L

Publication Date: 2022

Variant appearance in text: EGFR: R108K

PubMed Link: 36263208

Variant Present in the following documents:

• DataSheet_2.pdf

View BVdb publication page

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Comprehensive analyses of genomic features and mutational signatures in adenosquamous carcinoma of the lung.

Frontiers In Oncology

Wang, Hongbiao H; Liu, Jun J; Zhu, Sujuan S; Miao, Kun K; Li, Zhifeng Z; Qi, Xiaofang X; Huang, Lujia L; Guo, Lijie L; Wang, Yan Y; Cai, Yuyin Y; Lin, Yingcheng Y

Publication Date: 2022

Variant appearance in text: EGFR: R108K

PubMed Link: 36185247

Variant Present in the following documents:

• Main text
• fonc-12-945843.pdf

View BVdb publication page

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Clinical features and spectrum of NOTCH3 variants in Finnish patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Acta Neurologica Scandinavica

Mönkäre, Saana S; Kuuluvainen, Liina L; Schleutker, Johanna J; Myllykangas, Liisa L; Pöyhönen, Minna M

Publication Date: 2022-11

Variant appearance in text: EGFR: 323G>A

PubMed Link: 36086804

Variant Present in the following documents:

• Main text

View BVdb publication page

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Improvements in Quality Control and Library Preparation for Targeted Sequencing Allowed Detection of Potentially Pathogenic Alterations in Circulating Cell-Free DNA Derived from Plasma of Brain Tumor Patients.

Cancers

Szadkowska, Paulina P; Roura, Adria-Jaume AJ; Wojtas, Bartosz B; Wojnicki, Kamil K; Licholai, Sabina S; Waller, Tomasz T; Gubala, Tomasz T; Zukowski, Kacper K; Karpeta, Michal M; Wilkus, Kinga K; Kaspera, Wojciech W; Nawrocki, Sergiusz S; Kaminska, Bozena B

Publication Date: 2022-08-12

Variant appearance in text: rs1057519828

PubMed Link: 36010895

Variant Present in the following documents:

• cancers-14-03902.pdf

View BVdb publication page

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Identification of potential targets of the curcumin analog CCA-1.1 for glioblastoma treatment : integrated computational analysis and in vitro study.

Scientific Reports

Hermawan, Adam A; Wulandari, Febri F; Hanif, Naufa N; Utomo, Rohmad Yudi RY; Jenie, Riris Istighfari RI; Ikawati, Muthi M; Tafrihani, Ahmad Syauqy AS

Publication Date: 2022-08-17

Variant appearance in text: EGFR: 323G>A; R108K

PubMed Link: 35977996

Variant Present in the following documents:

• 41598_2022_18348_MOESM3_ESM.xlsx, sheet 6

View BVdb publication page

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Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma.

Nature Communications

Coy, Shannon S; Wang, Shu S; Stopka, Sylwia A SA; Lin, Jia-Ren JR; Yapp, Clarence C; Ritch, Cecily C CC; Salhi, Lisa L; Baker, Gregory J GJ; Rashid, Rumana R; Baquer, Gerard G; Regan, Michael M; Khadka, Prasidda P; Cole, Kristina A KA; Hwang, Jaeho J; Wen, Patrick Y PY; Bandopadhayay, Pratiti P; Santi, Mariarita M; De Raedt, Thomas T; Ligon, Keith L KL; Agar, Nathalie Y R NYR; Sorger, Peter K PK; Touat, Mehdi M; Santagata, Sandro S

Publication Date: 2022-08-16

Variant appearance in text: EGFR: R108K

PubMed Link: 35973991

Variant Present in the following documents:

• 41467_2022_32430_MOESM17_ESM.xlsx, sheet 12

View BVdb publication page

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S645C Point Mutation Suppresses Degradation of EGFR to Promote Progression of Glioblastoma.

Frontiers In Oncology

Huang, Wenda W; Zou, Ling L; Hao, Zhaonian Z; Wang, Baofeng B; Mao, Feng F; Duan, Qiuhong Q; Guo, Dongsheng D

Publication Date: 2022

Variant appearance in text: EGFR: R108K

PubMed Link: 35814475

Variant Present in the following documents:

• Main text
• fonc-12-904383.pdf

View BVdb publication page

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Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: EGFR: 323G>A; R108K

PubMed Link: 35814426

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

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Distribution and favorable prognostic implication of genomic EGFR alterations in IDH-wildtype glioblastoma.

Cancer Medicine

Higa, Nayuta N; Akahane, Toshiaki T; Hamada, Taiji T; Yonezawa, Hajime H; Uchida, Hiroyuki H; Makino, Ryutaro R; Watanabe, Shoji S; Takajo, Tomoko T; Yokoyama, Seiya S; Kirishima, Mari M; Matsuo, Kei K; Fujio, Shingo S; Hanaya, Ryosuke R; Tanimoto, Akihide A; Yoshimoto, Koji K

Publication Date: 2022-06-13

Variant appearance in text: EGFR: R108K

PubMed Link: 35695190

Variant Present in the following documents:

• Main text
• CAM4-12-49.pdf

View BVdb publication page

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Efficacy of dacomitinib in patients with non-small cell lung cancer carrying complex EGFR mutations: a real-world study.

Journal Of Thoracic Disease

Li, Hong-Shuai HS; Li, Jun-Ling JL; Yan, Xiang X; Xu, Hai-Yan HY; Zhou, Li-Qiang LQ; Hu, Xing-Sheng XS; Wang, Yu-Ying YY; Lei, Si-Yu SY; Wang, Yan Y

Publication Date: 2022-05

Variant appearance in text: EGFR: R108K

PubMed Link: 35693621

Variant Present in the following documents:

• Main text
• jtd-14-05-1428.pdf

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: EGFR: 323G>A; R108K

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW

Publication Date: 2022-05-23

Variant appearance in text: EGFR: 323G>A; Arg108Lys

PubMed Link: 35606799

Variant Present in the following documents:

• 41021_2022_248_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Bmc Medical Genomics

Sobahy, Turki M TM; Tashkandi, Ghassan G; Bahussain, Donya D; Al-Harbi, Raneem R

Publication Date: 2022-04-25

Variant appearance in text: EGFR: 323G>A

PubMed Link: 35468810

Variant Present in the following documents:

• 12920_2022_1235_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Genomic Analysis of Tumors from Patients with Glioblastoma with Long-Term Response to Afatinib.

Oncotargets And Therapy

Owen, Scott S; Alken, Scheryll S; Alshami, Jad J; Guiot, Marie-Christine MC; Kavan, Petr P; Reardon, David A DA; Muanza, Thierry T; Gibson, Neil N; Pemberton, Karine K; Solca, Flavio F; Cseh, Agnieszka A; Saran, Frank F

Publication Date: 2022

Variant appearance in text: EGFR: R108K

PubMed Link: 35422631

Variant Present in the following documents:

• Main text

View BVdb publication page

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Prospective genomically guided identification of "early/evolving" and "undersampled" IDH-wildtype glioblastoma leads to improved clinical outcomes.

Neuro-Oncology

Zhang, Yalan Y; Lucas, Calixto-Hope G CG; Young, Jacob S JS; Morshed, Ramin A RA; McCoy, Lucie L; Oberheim Bush, Nancy Ann NA; Taylor, Jennie W JW; Daras, Mariza M; Butowski, Nicholas A NA; Villanueva-Meyer, Javier E JE; Cha, Soonmee S; Wrensch, Margaret M; Wiencke, John K JK; Lee, Julieann C JC; Pekmezci, Melike M; Phillips, Joanna J JJ; Perry, Arie A; Bollen, Andrew W AW; Aghi, Manish K MK; Theodosopoulos, Philip P; Chang, Edward F EF; Hervey-Jumper, Shawn L SL; Berger, Mitchel S MS; Clarke, Jennifer L JL; Chang, Susan M SM; Molinaro, Annette M AM; Solomon, David A DA

Publication Date: 2022-10-03

Variant appearance in text: EGFR: 323G>A; R108K

PubMed Link: 35395677

Variant Present in the following documents:

• noac089_suppl_supplementary_tables_s1-s11.xlsx, sheet 5

View BVdb publication page

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Case Report: Benefits of a NSCLC Patient With EGFR A289G/F287_G288insHA cis Mutations From Immunotherapy in Combination With Antiangiogenesis and Chemotherapy and Sequential Treatment of EGFR-TKI.

Frontiers In Oncology

Zhang, He H; Dong, Weiwei W; Zhao, Huixia H; Hu, Yanyan Y; You, Xia X; Sun, Tingting T; Xiao, Wenhua W

Publication Date: 2022

Variant appearance in text: EGFR: R108K

PubMed Link: 35251994

Variant Present in the following documents:

• Main text
• fonc-12-826938.pdf

View BVdb publication page

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: EGFR: Arg108Lys

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.

Nature Biotechnology

Sánchez-Rivera, Francisco J FJ; Diaz, Bianca J BJ; Kastenhuber, Edward R ER; Schmidt, Henri H; Katti, Alyna A; Kennedy, Margaret M; Tem, Vincent V; Ho, Yu-Jui YJ; Leibold, Josef J; Paffenholz, Stella V SV; Barriga, Francisco M FM; Chu, Kevan K; Goswami, Sukanya S; Wuest, Alexandra N AN; Simon, Janelle M JM; Tsanov, Kaloyan M KM; Chakravarty, Debyani D; Zhang, Hongxin H; Leslie, Christina S CS; Lowe, Scott W SW; Dow, Lukas E LE

Publication Date: 2022-06

Variant appearance in text: EGFR: R108K

PubMed Link: 35165384

Variant Present in the following documents:

• NIHMS1760571-supplement-Supplementary_Table_S7.xlsx, sheet 5
• NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 4
• NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 6

View BVdb publication page

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Landscape of driver gene events, biomarkers, and druggable targets identified by whole-genome sequencing of glioblastomas.

Neuro-Oncology Advances

van de Geer, Wesley S WS; Hoogstrate, Youri Y; Draaisma, Kaspar K; Robe, Pierre A PA; Bins, Sander S; Mathijssen, Ron H J RHJ; French, Pim P; van de Werken, Harmen J G HJG; de Vos, Filip Y F FYF

Publication Date: 2022

Variant appearance in text: EGFR: Arg108Lys

PubMed Link: 35047820

Variant Present in the following documents:

• vdab177_suppl_supplementary_data.xlsx, sheet 6

View BVdb publication page

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Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: EGFR: 323G>A; Arg108Lys

PubMed Link: 35031014

Variant Present in the following documents:

• 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: EGFR: 323G>A; Arg108Lys

PubMed Link: 35031014

Variant Present in the following documents:

• 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Ultrasensitive analysis of genetic instability related to chemical exposure.

Journal Of Applied Genetics

Domoradzki, Tomasz T; Grochowski, Piotr P; Jaśkiewicz, Anna A; Pająk, Beata B

Publication Date: 2022-05

Variant appearance in text: EGFR: R108K

PubMed Link: 34967917

Variant Present in the following documents:

• Main text
• 13353_2021_Article_677.pdf

View BVdb publication page

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Tyrosine Kinase Inhibitors in Adult Glioblastoma: An (Un)Closed Chapter?

Cancers

Aldaz, Paula P; Arozarena, Imanol I

Publication Date: 2021-11-18

Variant appearance in text: EGFR: R108K

PubMed Link: 34830952

Variant Present in the following documents:

• Main text

View BVdb publication page

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Receptor tyrosine kinases as druggable targets in glioblastoma: Do signaling pathways matter?

Neuro-Oncology Advances

Qin, Anna A; Musket, Anna A; Musich, Phillip R PR; Schweitzer, John B JB; Xie, Qian Q

Publication Date: 2021

Variant appearance in text: EGFR: R108K

PubMed Link: 34806012

Variant Present in the following documents:

• Main text
• vdab133.pdf

View BVdb publication page

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Liquid Biopsy and Primary Brain Tumors.

Cancers

Eibl, Robert H RH; Schneemann, Markus M

Publication Date: 2021-10-29

Variant appearance in text: EGFR: R108K

PubMed Link: 34771592

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies.

Oncogene

Findlay, Izac J IJ; De Iuliis, Geoffry N GN; Duchatel, Ryan J RJ; Jackson, Evangeline R ER; Vitanza, Nicholas A NA; Cain, Jason E JE; Waszak, Sebastian M SM; Dun, Matthew D MD

Publication Date: 2021-11-10

Variant appearance in text: EGFR: R108K

PubMed Link: 34759345

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies.

Oncogene

Findlay, Izac J IJ; De Iuliis, Geoffry N GN; Duchatel, Ryan J RJ; Jackson, Evangeline R ER; Vitanza, Nicholas A NA; Cain, Jason E JE; Waszak, Sebastian M SM; Dun, Matthew D MD

Publication Date: 2022-01

Variant appearance in text: EGFR: R108K

PubMed Link: 34759345

Variant Present in the following documents:

• Main text

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: R108K

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Characterization of the Genomic and Immunologic Diversity of Malignant Brain Tumors through Multisector Analysis.

Cancer Discovery

Schaettler, Maximilian O MO; Richters, Megan M MM; Wang, Anthony Z AZ; Skidmore, Zachary L ZL; Fisk, Bryan B; Miller, Katherine E KE; Vickery, Tammi L TL; Kim, Albert H AH; Chicoine, Michael R MR; Osbun, Joshua W JW; Leuthardt, Eric C EC; Dowling, Joshua L JL; Zipfel, Gregory J GJ; Dacey, Ralph G RG; Lu, Hsiang-Chih HC; Johanns, Tanner M TM; Griffith, Obi L OL; Mardis, Elaine R ER; Griffith, Malachi M; Dunn, Gavin P GP

Publication Date: 2022-01

Variant appearance in text: EGFR: 323G>A; Arg108Lys; rs1057519828

PubMed Link: 34610950

Variant Present in the following documents:

• cd-21-0291_supplementary_table_1_suppst1.xlsx, sheet 36
• cd-21-0291_supplementary_table_3_suppst3.xlsx, sheet 36
• cd-21-0291_supplementary_table_4_suppst4.xlsx, sheet 36
• cd-21-0291_supplementary_table_4_suppst4.xlsx, sheet 34
• cd-21-0291_supplementary_table_3_suppst3.xlsx, sheet 35
• cd-21-0291_supplementary_table_4_suppst4.xlsx, sheet 35
• cd-21-0291_supplementary_table_3_suppst3.xlsx, sheet 34
• cd-21-0291_supplementary_table_1_suppst1.xlsx, sheet 35
• cd-21-0291_supplementary_table_1_suppst1.xlsx, sheet 34

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Arg108Lys

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Arg108Lys

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

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Metastatic Castration-Resistant Prostate Cancer Remains Dependent on Oncogenic Drivers Found in Primary Tumors.

Jco Precision Oncology

Einstein, David J DJ; Arai, Seiji S; Calagua, Carla C; Xie, Fang F; Voznesensky, Olga O; Capaldo, Brian J BJ; Luffman, Christina C; Hecht, Jonathan L JL; Balk, Steven P SP; Sowalsky, Adam G AG; Russo, Joshua W JW

Publication Date: 2021

Variant appearance in text: EGFR: R108K

PubMed Link: 34568716

Variant Present in the following documents:

• Main text

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Metastatic Castration-Resistant Prostate Cancer Remains Dependent on Oncogenic Drivers Found in Primary Tumors.

Jco Precision Oncology

Einstein, David J DJ; Arai, Seiji S; Calagua, Carla C; Xie, Fang F; Voznesensky, Olga O; Capaldo, Brian J BJ; Luffman, Christina C; Hecht, Jonathan L JL; Balk, Steven P SP; Sowalsky, Adam G AG; Russo, Joshua W JW

Publication Date: 2021

Variant appearance in text: EGFR: R108K

PubMed Link: 34568716

Variant Present in the following documents:

• Main text

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High-Affinity Chimeric Antigen Receptor With Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms.

Frontiers In Oncology

Thokala, Radhika R; Binder, Zev A ZA; Yin, Yibo Y; Zhang, Logan L; Zhang, Jiasi Vicky JV; Zhang, Daniel Y DY; Milone, Michael C MC; Ming, Guo-Li GL; Song, Hongjun H; O'Rourke, Donald M DM

Publication Date: 2021

Variant appearance in text: EGFR: R108K

PubMed Link: 34568006

Variant Present in the following documents:

• Main text

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Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (New York, N.Y.)

Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J

Publication Date: 2021-05-28

Variant appearance in text: EGFR: R108K

PubMed Link: 34557754

Variant Present in the following documents:

• Main text

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Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (Cambridge (Mass.))

Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J

Publication Date: 2021-05-28

Variant appearance in text: EGFR: R108K

PubMed Link: 34557754

Variant Present in the following documents:

• Main text

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Establishment of an Endocytosis-Related Prognostic Signature for Patients With Low-Grade Glioma.

Frontiers In Genetics

Wang, Dawei D; Liu, Shiguang S; Wang, Guangxin G

Publication Date: 2021

Variant appearance in text: EGFR: R108K

PubMed Link: 34552618

Variant Present in the following documents:

• Main text
• fgene-12-709666.pdf

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Multi-region exome sequencing reveals the intratumoral heterogeneity of surgically resected small cell lung cancer.

Nature Communications

Zhou, Huaqiang H; Hu, Yi Y; Luo, Rongzhen R; Zhao, Yuanyuan Y; Pan, Hui H; Ji, Liyan L; Zhou, Ting T; Zhang, Lanjun L; Long, Hao H; Fu, Jianhua J; Wen, Zhesheng Z; Wang, Siyu S; Wang, Xin X; Lin, Peng P; Yang, Haoxian H; Wang, Junye J; Song, Mengmeng M; Yi, Xin X; Yang, Ling L; Xia, Xuefang X; Guan, Yanfang Y; Fang, Wenfeng W; Yang, Yunpeng Y; Hong, Shaodong S; Huang, Yan Y; Li, Pansong P; Zhang, Yaxiong Y; Zhou, Ningning N

Publication Date: 2021-09-14

Variant appearance in text: EGFR: Arg108Lys

PubMed Link: 34521849

Variant Present in the following documents:

• Main text
• 41467_2021_Article_25787.pdf
• 41467_2021_25787_MOESM10_ESM.xlsx, sheet 7
• 41467_2021_25787_MOESM8_ESM.xlsx, sheet 1
• 41467_2021_25787_MOESM4_ESM.xlsx, sheet 1

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A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.

Cancers

Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC

Publication Date: 2021-07-20

Variant appearance in text: EGFR: R108K

PubMed Link: 34298851

Variant Present in the following documents:

• Main text

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Fragmentation patterns and personalized sequencing of cell-free DNA in urine and plasma of glioma patients.

Embo Molecular Medicine

Mouliere, Florent F; Smith, Christopher G CG; Heider, Katrin K; Su, Jing J; van der Pol, Ymke Y; Thompson, Mareike M; Morris, James J; Wan, Jonathan C M JCM; Chandrananda, Dineika D; Hadfield, James J; Grzelak, Marta M; Hudecova, Irena I; Couturier, Dominique-Laurent DL; Cooper, Wendy W; Zhao, Hui H; Gale, Davina D; Eldridge, Matthew M; Watts, Colin C; Brindle, Kevin K; Rosenfeld, Nitzan N; Mair, Richard R

Publication Date: 2021-08-09

Variant appearance in text: EGFR: 323G>A; Arg108Lys

PubMed Link: 34291583

Variant Present in the following documents:

• EMMM-13-e12881-s004.xlsx, sheet 1
• EMMM-13-e12881-s010.xlsx, sheet 1

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Nivolumab Plus Ipilimumab vs Nivolumab for Previously Treated Patients With Stage IV Squamous Cell Lung Cancer: The Lung-MAP S1400I Phase 3 Randomized Clinical Trial.

Jama Oncology

Gettinger, Scott N SN; Redman, Mary W MW; Bazhenova, Lyudmila L; Hirsch, Fred R FR; Mack, Philip C PC; Schwartz, Lawrence H LH; Bradley, Jeffrey D JD; Stinchcombe, Thomas E TE; Leighl, Natasha B NB; Ramalingam, Suresh S SS; Tavernier, Susan S SS; Yu, Hui H; Unger, Joseph M JM; Minichiello, Katherine K; Highleyman, Louise L; Papadimitrakopoulou, Vassiliki A VA; Kelly, Karen K; Gandara, David R DR; Herbst, Roy S RS

Publication Date: 2021-09-01

Variant appearance in text: EGFR: R108K

PubMed Link: 34264316

Variant Present in the following documents:

• jamaoncol-e212209-s002.pdf

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