Publications:

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: G203R

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

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A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research

Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H

Publication Date: 2022-01

Variant appearance in text: EGFR: G203R

PubMed Link: 34963661

Variant Present in the following documents:

• supp_gr.275437.121_Supplementary_Table_1.xlsx, sheet 3

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 607G>A

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

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ErBb Family Proteins in Cholangiocarcinoma and Clinical Implications.

Journal Of Clinical Medicine

Jin, Wook W

Publication Date: 2020-07-16

Variant appearance in text: EGFR: G203R

PubMed Link: 32708604

Variant Present in the following documents:

• Main text
• jcm-09-02255.pdf

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ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin β1 recycling in cell migration.

The Journal Of Biological Chemistry

Yu, Xue X; Wang, Fengsong F; Liu, Hongsheng H; Adams, Gregory G; Aikhionbare, Felix F; Liu, Dong D; Cao, Xinwang X; Fan, Libin L; Hu, Guohong G; Chen, Yong Y; Frost, Andra A; Partridge, Edward E; Ding, Xia X; Yao, Xuebiao X

Publication Date: 2011-12-23

Variant appearance in text: EGFR: G203R

PubMed Link: 22027826

Variant Present in the following documents:

• Main text

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Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor.

Nature Communications

Hanafusa, Hiroshi H; Ishikawa, Kouki K; Kedashiro, Shin S; Saigo, Tsukasa T; Iemura, Shun-Ichiro S; Natsume, Tohru T; Komada, Masayuki M; Shibuya, Hiroshi H; Nara, Atsuki A; Matsumoto, Kunihiro K

Publication Date: 2011-01-18

Variant appearance in text: EGFR: G203R

PubMed Link: 21245839

Variant Present in the following documents:

• Main text
• ncomms1161.pdf

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Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits.

Molecular And Cellular Biology

Johannessen, Lene E LE; Pedersen, Nina Marie NM; Pedersen, Ketil Winther KW; Madshus, Inger Helene IH; Stang, Espen E

Publication Date: 2006-01

Variant appearance in text: EGFR: G203R

PubMed Link: 16382132

Variant Present in the following documents:

• Main text

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Grb2 regulates internalization of EGF receptors through clathrin-coated pits.

Molecular Biology Of The Cell

Jiang, Xuejun X; Huang, Fangtian F; Marusyk, Andriy A; Sorkin, Alexander A

Publication Date: 2003-03

Variant appearance in text: EGFR: G203R

PubMed Link: 12631709

Variant Present in the following documents:

• Main text

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A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling.

The Embo Journal

Waterman, Hadassa H; Katz, Menachem M; Rubin, Chanan C; Shtiegman, Keren K; Lavi, Sara S; Elson, Ari A; Jovin, Thomas T; Yarden, Yosef Y

Publication Date: 2002-02-01

Variant appearance in text: EGFR: G203R

PubMed Link: 11823423

Variant Present in the following documents:

• Main text

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