Publications:

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Phytochemical Constituents and Derivatives of Cannabis sativa; Bridging the Gap in Melanoma Treatment.

International Journal Of Molecular Sciences

Schanknecht, Ellen E; Bachari, Ava A; Nassar, Nazim N; Piva, Terrence T; Mantri, Nitin N

Publication Date: 2023-01-03

Variant appearance in text: EGFR: A375P

PubMed Link: 36614303

Variant Present in the following documents:

• Main text
• ijms-24-00859.pdf

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Urokinase-type plasminogen activator receptor (uPAR) as a therapeutic target in cancer.

Journal Of Translational Medicine

Zhai, Bing-Tao BT; Tian, Huan H; Sun, Jing J; Zou, Jun-Bo JB; Zhang, Xiao-Fei XF; Cheng, Jiang-Xue JX; Shi, Ya-Jun YJ; Fan, Yu Y; Guo, Dong-Yan DY

Publication Date: 2022-03-18

Variant appearance in text: EGFR: A375p

PubMed Link: 35303878

Variant Present in the following documents:

• Main text
• 12967_2022_Article_3329.pdf

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Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial.

Lancet (London, England)

Gershenson, David M DM; Miller, Austin A; Brady, William E WE; Paul, James J; Carty, Karen K; Rodgers, William W; Millan, David D; Coleman, Robert L RL; Moore, Kathleen N KN; Banerjee, Susana S; Connolly, Kate K; Secord, Angeles Alvarez AA; O'Malley, David M DM; Dorigo, Oliver O; Gaillard, Stephanie S; Gabra, Hani H; Slomovitz, Brian B; Hanjani, Parviz P; Farley, John J; Churchman, Michael M; Ewing, Ailith A; Hollis, Robert L RL; Herrington, C Simon CS; Huang, Helen Q HQ; Wenzel, Lari L; Gourley, Charlie C

Publication Date: 2022-02-05

Variant appearance in text: EGFR: A375P

PubMed Link: 35123694

Variant Present in the following documents:

• mmc1.pdf

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Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial.

Lancet (London, England)

Gershenson, David M DM; Miller, Austin A; Brady, William E WE; Paul, James J; Carty, Karen K; Rodgers, William W; Millan, David D; Coleman, Robert L RL; Moore, Kathleen N KN; Banerjee, Susana S; Connolly, Kate K; Secord, Angeles Alvarez AA; O'Malley, David M DM; Dorigo, Oliver O; Gaillard, Stephanie S; Gabra, Hani H; Slomovitz, Brian B; Hanjani, Parviz P; Farley, John J; Churchman, Michael M; Ewing, Ailith A; Hollis, Robert L RL; Herrington, C Simon CS; Huang, Helen Q HQ; Wenzel, Lari L; Gourley, Charlie C

Publication Date: 2022-02-05

Variant appearance in text: EGFR: A375P

PubMed Link: 35123694

Variant Present in the following documents:

• mmc1.pdf

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Evaluation of Substituted Pyrazole-Based Kinase Inhibitors in One Decade (2011-2020): Current Status and Future Prospects.

Molecules (Basel, Switzerland)

El-Gamal, Mohammed I MI; Zaraei, Seyed-Omar SO; Madkour, Moustafa M MM; Anbar, Hanan S HS

Publication Date: 2022-01-05

Variant appearance in text: EGFR: A375P

PubMed Link: 35011562

Variant Present in the following documents:

• Main text

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Evaluation of Substituted Pyrazole-Based Kinase Inhibitors in One Decade (2011-2020): Current Status and Future Prospects.

Molecules (Basel, Switzerland)

El-Gamal, Mohammed I MI; Zaraei, Seyed-Omar SO; Madkour, Moustafa M MM; Anbar, Hanan S HS

Publication Date: 2022-01-05

Variant appearance in text: EGFR: A375P

PubMed Link: 35011562

Variant Present in the following documents:

• Main text

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CRISPR/Cas9 uPAR Gene Knockout Results in Tumor Growth Inhibition, EGFR Downregulation and Induction of Stemness Markers in Melanoma and Colon Carcinoma Cell Lines.

Frontiers In Oncology

Biagioni, Alessio A; Chillà, Anastasia A; Del Rosso, Mario M; Fibbi, Gabriella G; Scavone, Francesca F; Andreucci, Elena E; Peppicelli, Silvia S; Bianchini, Francesca F; Calorini, Lido L; Li Santi, Anna A; Ragno, Pia P; Margheri, Francesca F; Laurenzana, Anna A

Publication Date: 2021

Variant appearance in text: EGFR: A375p

PubMed Link: 34055629

Variant Present in the following documents:

• Main text
• fonc-11-663225.pdf

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The converging roles of Batten disease proteins in neurodegeneration and cancer.

Iscience

Yap, Shyong Quan SQ; Mathavarajah, Sabateeshan S; Huber, Robert Joseph RJ

Publication Date: 2021-04-23

Variant appearance in text: EGFR: A375P

PubMed Link: 33889828

Variant Present in the following documents:

• Main text

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Mutational drivers of cancer cell migration and invasion.

British Journal Of Cancer

Novikov, Nikita M NM; Zolotaryova, Sofia Y SY; Gautreau, Alexis M AM; Denisov, Evgeny V EV

Publication Date: 2021-01

Variant appearance in text: EGFR: A375P

PubMed Link: 33204027

Variant Present in the following documents:

• Main text
• 41416_2020_Article_1149.pdf

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Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma: A Systematic Review.

Cancers

Proietti, Ilaria I; Skroza, Nevena N; Bernardini, Nicoletta N; Tolino, Ersilia E; Balduzzi, Veronica V; Marchesiello, Anna A; Michelini, Simone S; Volpe, Salvatore S; Mambrin, Alessandra A; Mangino, Giorgio G; Romeo, Giovanna G; Maddalena, Patrizia P; Rees, Catherine C; Potenza, Concetta C

Publication Date: 2020-09-29

Variant appearance in text: EGFR: A375P

PubMed Link: 33003483

Variant Present in the following documents:

• Main text
• cancers-12-02801.pdf

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Metabolic Adaptations in Cancer Stem Cells.

Frontiers In Oncology

Yadav, Umesh Prasad UP; Singh, Tashvinder T; Kumar, Pramit P; Sharma, Praveen P; Kaur, Harsimrat H; Sharma, Sadhana S; Singh, Sandeep S; Kumar, Santosh S; Mehta, Kapil K

Publication Date: 2020

Variant appearance in text: EGFR: A375P

PubMed Link: 32670883

Variant Present in the following documents:

• Main text

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Cancer Nanomedicine Special Issue Review Anticancer Drug Delivery with Nanoparticles: Extracellular Vesicles or Synthetic Nanobeads as Therapeutic Tools for Conventional Treatment or Immunotherapy.

Cancers

Zocchi, Maria Raffaella MR; Tosetti, Francesca F; Benelli, Roberto R; Poggi, Alessandro A

Publication Date: 2020-07-13

Variant appearance in text: EGFR: A375P

PubMed Link: 32668783

Variant Present in the following documents:

• Main text

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MicroRNAs as Key Players in Melanoma Cell Resistance to MAPK and Immune Checkpoint Inhibitors.

International Journal Of Molecular Sciences

Motti, Maria Letizia ML; Minopoli, Michele M; Di Carluccio, Gioconda G; Ascierto, Paolo Antonio PA; Carriero, Maria Vincenza MV

Publication Date: 2020-06-26

Variant appearance in text: EGFR: A375P

PubMed Link: 32604720

Variant Present in the following documents:

• Main text
• ijms-21-04544.pdf

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Anti-Inflammatory Drugs as Anticancer Agents.

International Journal Of Molecular Sciences

Zappavigna, Silvia S; Cossu, Alessia Maria AM; Grimaldi, Anna A; Bocchetti, Marco M; Ferraro, Giuseppe Andrea GA; Nicoletti, Giovanni Francesco GF; Filosa, Rosanna R; Caraglia, Michele M

Publication Date: 2020-04-09

Variant appearance in text: EGFR: A375P

PubMed Link: 32283655

Variant Present in the following documents:

• Main text
• ijms-21-02605.pdf

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uPAR Knockout Results in a Deep Glycolytic and OXPHOS Reprogramming in Melanoma and Colon Carcinoma Cell Lines.

Cells

Biagioni, Alessio A; Laurenzana, Anna A; Chillà, Anastasia A; Del Rosso, Mario M; Andreucci, Elena E; Poteti, Martina M; Bani, Daniele D; Guasti, Daniele D; Fibbi, Gabriella G; Margheri, Francesca F

Publication Date: 2020-01-28

Variant appearance in text: EGFR: A375p

PubMed Link: 32012858

Variant Present in the following documents:

• Main text
• cells-09-00308.pdf

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EPHB6 mutation induces cell adhesion-mediated paclitaxel resistance via EPHA2 and CDH11 expression.

Experimental & Molecular Medicine

Yoon, Sarah S; Choi, Ji-Hye JH; Kim, Sung Joo SJ; Lee, Eun-Ju EJ; Shah, Masaud M; Choi, Sangdun S; Woo, Hyun Goo HG

Publication Date: 2019-06-03

Variant appearance in text: EGFR: A375P

PubMed Link: 31160603

Variant Present in the following documents:

• Main text
• 12276_2019_Article_261.pdf

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Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.

Nature Communications

Talebi, Ali A; Dehairs, Jonas J; Rambow, Florian F; Rogiers, Aljosja A; Nittner, David D; Derua, Rita R; Vanderhoydonc, Frank F; Duarte, Joao A G JAG; Bosisio, Francesca F; Van den Eynde, Kathleen K; Nys, Kris K; Pérez, Mónica Vara MV; Agostinis, Patrizia P; Waelkens, Etienne E; Van den Oord, Joost J; Fendt, Sarah-Maria SM; Marine, Jean-Christophe JC; Swinnen, Johannes V JV

Publication Date: 2018-06-27

Variant appearance in text: EGFR: A375p

PubMed Link: 29950559

Variant Present in the following documents:

• 41467_2018_Article_4664.pdf

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Tissue-Dependent Tumor Microenvironments and Their Impact on Immunotherapy Responses.

Frontiers In Immunology

Oliver, Amanda J AJ; Lau, Peter K H PKH; Unsworth, Ashleigh S AS; Loi, Sherene S; Darcy, Phillip K PK; Kershaw, Michael H MH; Slaney, Clare Y CY

Publication Date: 2018

Variant appearance in text: EGFR: A375P

PubMed Link: 29445373

Variant Present in the following documents:

• Main text
• fimmu-09-00070.pdf

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Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells.

Journal Of Experimental & Clinical Cancer Research : Cr

Ragone, Concetta C; Minopoli, Michele M; Ingangi, Vincenzo V; Botti, Giovanni G; Fratangelo, Federica F; Pessi, Antonello A; Stoppelli, Maria Patrizia MP; Ascierto, Paolo Antonio PA; Ciliberto, Gennaro G; Motti, Maria Letizia ML; Carriero, Maria Vincenza MV

Publication Date: 2017-12-08

Variant appearance in text: EGFR: A375P

PubMed Link: 29216889

Variant Present in the following documents:

• Main text
• 13046_2017_Article_650.pdf

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ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells.

Autophagy

Piao, Shengfu S; Ojha, Rani R; Rebecca, Vito W VW; Samanta, Arabinda A; Ma, Xiao-Hong XH; Mcafee, Quentin Q; Nicastri, Michael C MC; Buckley, Meghan M; Brown, Eric E; Winkler, Jeffrey D JD; Gimotty, Phyllis A PA; Amaravadi, Ravi K RK

Publication Date: 2017

Variant appearance in text: EGFR: A375P

PubMed Link: 28981387

Variant Present in the following documents:

• Main text

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Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases.

Theranostics

Ha, Helen H; Debnath, Bikash B; Neamati, Nouri N

Publication Date: 2017

Variant appearance in text: EGFR: A375P

PubMed Link: 28529637

Variant Present in the following documents:

• Main text
• thnov07p1543.pdf

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Notch3 signaling-mediated melanoma-endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis.

Laboratory Investigation; A Journal Of Technical Methods And Pathology

Hsu, Mei-Yu MY; Yang, Moon Hee MH; Schnegg, Caroline I CI; Hwang, Soonyean S; Ryu, Byungwoo B; Alani, Rhoda M RM

Publication Date: 2017-06

Variant appearance in text: EGFR: A375P

PubMed Link: 28165469

Variant Present in the following documents:

• nihms838887.pdf

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Selective Covalent Targeting of Anti-Apoptotic BFL-1 by Cysteine-Reactive Stapled Peptide Inhibitors.

Cell Chemical Biology

Huhn, Annissa J AJ; Guerra, Rachel M RM; Harvey, Edward P EP; Bird, Gregory H GH; Walensky, Loren D LD

Publication Date: 2016-09-22

Variant appearance in text: EGFR: A375P

PubMed Link: 27617850

Variant Present in the following documents:

• Main text

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Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death.

International Journal Of Oncology

Shan, Xiu X; Tian, Li Li LL; Zhang, Yu Mei YM; Wang, Xiao Qi XQ; Yan, Qiu Q; Liu, Ji Wei JW

Publication Date: 2015-08

Variant appearance in text: EGFR: A375P

PubMed Link: 26094873

Variant Present in the following documents:

• Main text
• ijo-47-02-0701.pdf

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ERBB3 is required for metastasis formation of melanoma cells.

Oncogenesis

Tiwary, S S; Preziosi, M M; Rothberg, P G PG; Zeitouni, N N; Corson, N N; Xu, L L

Publication Date: 2014-07-07

Variant appearance in text: ERBB: A375P

PubMed Link: 25000258

Variant Present in the following documents:

• Main text

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Double-stranded DNA in exosomes: a novel biomarker in cancer detection.

Cell Research

Thakur, Basant Kumar BK; Zhang, Haiying H; Becker, Annette A; Matei, Irina I; Huang, Yujie Y; Costa-Silva, Bruno B; Zheng, Yan Y; Hoshino, Ayuko A; Brazier, Helene H; Xiang, Jenny J; Williams, Caitlin C; Rodriguez-Barrueco, Ruth R; Silva, Jose M JM; Zhang, Weijia W; Hearn, Stephen S; Elemento, Olivier O; Paknejad, Navid N; Manova-Todorova, Katia K; Welte, Karl K; Bromberg, Jacqueline J; Peinado, Héctor H; Lyden, David D

Publication Date: 2014-06

Variant appearance in text: EGFR: A375P

PubMed Link: 24710597

Variant Present in the following documents:

• cr201444x7.pdf

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Autophagy-Dependent Survival of Mutant B-Raf Melanoma Cells Selected for Resistance to Apoptosis Induced by Inhibitors against Oncogenic B-Raf.

Biomolecules & Therapeutics

Ahn, Jun-Ho JH; Lee, Michael M

Publication Date: 2013-03

Variant appearance in text: EGFR: A375P

PubMed Link: 24009868

Variant Present in the following documents:

• ooomb4-21-114.pdf

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DIAPH3 governs the cellular transition to the amoeboid tumour phenotype.

Embo Molecular Medicine

Hager, Martin H MH; Morley, Samantha S; Bielenberg, Diane R DR; Gao, Sizhen S; Morello, Matteo M; Holcomb, Ilona N IN; Liu, Wennuan W; Mouneimne, Ghassan G; Demichelis, Francesca F; Kim, Jayoung J; Solomon, Keith R KR; Adam, Rosalyn M RM; Isaacs, William B WB; Higgs, Henry N HN; Vessella, Robert L RL; Di Vizio, Dolores D; Freeman, Michael R MR

Publication Date: 2012-08

Variant appearance in text: EGFR: A375P

PubMed Link: 22593025

Variant Present in the following documents:

• Main text
• emmm0004-0743-SD5.pdf
• emmm0004-0743.pdf

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microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C.

The Embo Journal

Penna, Elisa E; Orso, Francesca F; Cimino, Daniela D; Tenaglia, Enrico E; Lembo, Antonio A; Quaglino, Elena E; Poliseno, Laura L; Haimovic, Adele A; Osella-Abate, Simona S; De Pittà, Cristiano C; Pinatel, Eva E; Stadler, Michael B MB; Provero, Paolo P; Bernengo, Maria Grazia MG; Osman, Iman I; Taverna, Daniela D

Publication Date: 2011-05-18

Variant appearance in text: EGFR: A375P

PubMed Link: 21468029

Variant Present in the following documents:

• Main text

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Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases.

Molecular Cancer Research : Mcr

Xu, Lei L; Shen, Steven S SS; Hoshida, Yujin Y; Subramanian, Aravind A; Ross, Ken K; Brunet, Jean-Philippe JP; Wagner, Stephan N SN; Ramaswamy, Sridhar S; Mesirov, Jill P JP; Hynes, Richard O RO

Publication Date: 2008-05

Variant appearance in text: ERBB: A375P

PubMed Link: 18505921

Variant Present in the following documents:

• Main text

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Antitumour efficacy of VEGFR2 tyrosine kinase inhibitor correlates with expression of VEGF and its receptor VEGFR2 in tumour models.

British Journal Of Cancer

Dev, I K IK; Dornsife, R E RE; Hopper, T M TM; Onori, J A JA; Miller, C G CG; Harrington, L E LE; Dold, K M KM; Mullin, R J RJ; Johnson, J H JH; Crosby, R M RM; Truesdale, A T AT; Epperly, A H AH; Hinkle, K W KW; Cheung, M M; Stafford, J A JA; Luttrell, D K DK; Kumar, R R

Publication Date: 2004-10-04

Variant appearance in text: EGFR: A375P

PubMed Link: 15328520

Variant Present in the following documents:

• Main text
• 91-6602109a.pdf

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