EGFR c.1123_1125delinsATG ;(p.A375M)

Variant ID: 7-55224342-GCA-ATG

NM_005228.3(EGFR):c.1123_1125delinsATG;(p.A375M)

This variant was identified in 27 publications

View GRCh38 version.




Publications:


Novel Fab-peptide-HLA-I fusion proteins for redirecting pre-existing anti-CMV T cell immunity to selective eliminate carcinoma cells.

Oncoimmunology
Britsch, Isabel I; van Wijngaarden, Anne P AP; Ke, Xiurong X; Hendriks, Mark A J M MAJM; Samplonius, Douwe F DF; Ploeg, Emily M EM; Helfrich, Wijnand W
Publication Date: 2023

Variant appearance in text: EGFR: A375M
PubMed Link: 37180637
Variant Present in the following documents:
  • Main text
  • KONI_12_2207868.pdf
View BVdb publication page



Extracellular vesicles and melanoma: New perspectives on tumor microenvironment and metastasis.

Frontiers In Cell And Developmental Biology
Benito-Martín, Alberto A; Jasiulionis, Miriam Galvonas MG; García-Silva, Susana S
Publication Date: 2022

Variant appearance in text: EGFR: A375M
PubMed Link: 36704194
Variant Present in the following documents:
  • Main text
  • fcell-10-1061982.pdf
View BVdb publication page



Advances on Delivery of Cytotoxic Enzymes as Anticancer Agents.

Molecules (Basel, Switzerland)
Asrorov, Akmal M AM; Muhitdinov, Bahtiyor B; Tu, Bin B; Mirzaakhmedov, Sharafitdin S; Wang, Huiyuan H; Huang, Yongzhuo Y
Publication Date: 2022-06-14

Variant appearance in text: EGFR: A375M
PubMed Link: 35744957
Variant Present in the following documents:
  • Main text
  • molecules-27-03836.pdf
View BVdb publication page



Identification of Core Genes and Pathways in Melanoma Metastasis via Bioinformatics Analysis.

International Journal Of Molecular Sciences
Xie, Renjian R; Li, Bifei B; Jia, Lee L; Li, Yumei Y
Publication Date: 2022-01-12

Variant appearance in text: EGFR: A375M
PubMed Link: 35054979
Variant Present in the following documents:
  • Main text
  • ijms-23-00794.pdf
View BVdb publication page



Identification of Core Genes and Pathways in Melanoma Metastasis via Bioinformatics Analysis.

International Journal Of Molecular Sciences
Xie, Renjian R; Li, Bifei B; Jia, Lee L; Li, Yumei Y
Publication Date: 2022-01-12

Variant appearance in text: EGFR: A375M
PubMed Link: 35054979
Variant Present in the following documents:
  • Main text
  • ijms-23-00794.pdf
View BVdb publication page



Cancer cells under immune attack acquire CD47-mediated adaptive immune resistance independent of the myeloid CD47-SIRPα axis.

Oncoimmunology
Hendriks, Mark A J M MAJM; Britsch, Isabel I; Ke, Xiurong X; van Wijngarden, Anne P AP; Samplonius, Douwe F DF; Ploeg, Emily M EM; Helfrich, Wijnand W
Publication Date: 2021

Variant appearance in text: EGFR: A375m
PubMed Link: 34858730
Variant Present in the following documents:
  • Main text
  • KONI_10_2005344.pdf
View BVdb publication page



Cancer cells under immune attack acquire CD47-mediated adaptive immune resistance independent of the myeloid CD47-SIRPα axis.

Oncoimmunology
Hendriks, Mark A J M MAJM; Britsch, Isabel I; Ke, Xiurong X; van Wijngarden, Anne P AP; Samplonius, Douwe F DF; Ploeg, Emily M EM; Helfrich, Wijnand W
Publication Date: 2021

Variant appearance in text: EGFR: A375m
PubMed Link: 34858730
Variant Present in the following documents:
  • Main text
  • KONI_10_2005344.pdf
View BVdb publication page



Bispecific antibody approach for EGFR-directed blockade of the CD47-SIRPα "don't eat me" immune checkpoint promotes neutrophil-mediated trogoptosis and enhances antigen cross-presentation.

Oncoimmunology
Hendriks, Mark A J M MAJM; Ploeg, Emily M EM; Koopmans, Iris I; Britsch, Isabel I; Ke, Xiurong X; Samplonius, Douwe F DF; Helfrich, Wijnand W
Publication Date: 2020-09-29

Variant appearance in text: EGFR: A375m
PubMed Link: 33299654
Variant Present in the following documents:
  • Main text
View BVdb publication page



Dual mTOR/DNA-PK Inhibitor CC-115 Induces Cell Death in Melanoma Cells and Has Radiosensitizing Potential.

International Journal Of Molecular Sciences
Bürkel, Felix F; Jost, Tina T; Hecht, Markus M; Heinzerling, Lucie L; Fietkau, Rainer R; Distel, Luitpold L
Publication Date: 2020-12-07

Variant appearance in text: EGFR: A375M
PubMed Link: 33297429
Variant Present in the following documents:
  • ijms-21-09321.pdf
View BVdb publication page



In Vitro-Transcribed mRNA Chimeric Antigen Receptor T Cell (IVT mRNA CAR T) Therapy in Hematologic and Solid Tumor Management: A Preclinical Update.

International Journal Of Molecular Sciences
Soundara Rajan, Thangavelu T; Gugliandolo, Agnese A; Bramanti, Placido P; Mazzon, Emanuela E
Publication Date: 2020-09-06

Variant appearance in text: EGFR: A375M
PubMed Link: 32899932
Variant Present in the following documents:
  • Main text
  • ijms-21-06514.pdf
View BVdb publication page



Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies.

Nature Communications
Montero, Joan J; Gstalder, Cécile C; Kim, Daniel J DJ; Sadowicz, Dorota D; Miles, Wayne W; Manos, Michael M; Cidado, Justin R JR; Paul Secrist, J J; Tron, Adriana E AE; Flaherty, Keith K; Stephen Hodi, F F; Yoon, Charles H CH; Letai, Anthony A; Fisher, David E DE; Haq, Rizwan R
Publication Date: 2019-11-14

Variant appearance in text: EGFR: A375M
PubMed Link: 31727958
Variant Present in the following documents:
  • Main text
View BVdb publication page



Downregulation of KCTD12 contributes to melanoma stemness by modulating CD271.

Cancer Biology & Medicine
Shen, Weiyu W; Li, Yumei Y; Li, Bifei B; Zheng, Liping L; Xie, Xiaodong X; Le, Jingqing J; Lu, Yusheng Y; Li, Tao T; Chen, Fan F; Jia, Lee L
Publication Date: 2019-08

Variant appearance in text: EGFR: A375M
PubMed Link: 31565480
Variant Present in the following documents:
  • cbm-16-3-498.pdf
View BVdb publication page



Integrins: Moonlighting Proteins in Invadosome Formation.

Cancers
Peláez, Rafael R; Pariente, Ana A; Pérez-Sala, Álvaro Á; Larrayoz, Ignacio M IM
Publication Date: 2019-05-02

Variant appearance in text: EGFR: A375M
PubMed Link: 31052560
Variant Present in the following documents:
  • Main text
  • cancers-11-00615.pdf
View BVdb publication page



Interleukin-1 Beta-A Friend or Foe in Malignancies?

International Journal Of Molecular Sciences
Bent, Rebekka R; Moll, Lorna L; Grabbe, Stephan S; Bros, Matthias M
Publication Date: 2018-07-24

Variant appearance in text: EGFR: A375M
PubMed Link: 30042333
Variant Present in the following documents:
  • Main text
  • ijms-19-02155.pdf
View BVdb publication page



Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents.

Ecancermedicalscience
Verbaanderd, Ciska C; Maes, Hannelore H; Schaaf, Marco B MB; Sukhatme, Vikas P VP; Pantziarka, Pan P; Sukhatme, Vidula V; Agostinis, Patrizia P; Bouche, Gauthier G
Publication Date: 2017

Variant appearance in text: EGFR: A375m
PubMed Link: 29225688
Variant Present in the following documents:
  • Main text
  • can-11-781.pdf
View BVdb publication page



A versatile pretargeting approach for tumour-selective delivery and activation of TNF superfamily members.

Scientific Reports
He, Yuan Y; van Bommel, Peter E PE; Samplonius, Douwe F DF; Bremer, Edwin E; Helfrich, Wijnand W
Publication Date: 2017-10-16

Variant appearance in text: EGFR: A375m
PubMed Link: 29038485
Variant Present in the following documents:
  • Main text
  • 41598_2017_Article_13530.pdf
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Optochemical Control of Biological Processes in Cells and Animals.

Angewandte Chemie (International Ed. In English)
Ankenbruck, Nicholas N; Courtney, Taylor T; Naro, Yuta Y; Deiters, Alexander A
Publication Date: 2018-03-05

Variant appearance in text: EGFR: A375M
PubMed Link: 28521066
Variant Present in the following documents:
  • Main text
View BVdb publication page



Melanoma cells undergo aggressive coalescence in a 3D Matrigel model that is repressed by anti-CD44.

Plos One
Wessels, Deborah D; Lusche, Daniel F DF; Voss, Edward E; Kuhl, Spencer S; Buchele, Emma C EC; Klemme, Michael R MR; Russell, Kanoe B KB; Ambrose, Joseph J; Soll, Benjamin A BA; Bossler, Aaron A; Milhem, Mohammed M; Goldman, Charles C; Soll, David R DR
Publication Date: 2017

Variant appearance in text: EGFR: A375M
PubMed Link: 28264026
Variant Present in the following documents:
  • pone.0173400.pdf
View BVdb publication page



Hypofractionated radiotherapy for localized prostate cancer.

Strahlentherapie Und Onkologie : Organ Der Deutschen Rontgengesellschaft ... [Et Al]
Höcht, Stefan S; Aebersold, Daniel M DM; Albrecht, Clemens C; Böhmer, Dirk D; Flentje, Michael M; Ganswindt, Ute U; Hölscher, Tobias T; Martin, Thomas T; Sedlmayer, Felix F; Wenz, Frederik F; Zips, Daniel D; Wiegel, Thomas T
Publication Date: 2017-01

Variant appearance in text: EGFR: A375M
PubMed Link: 27628966
Variant Present in the following documents:
  • 66_2017_Article_1137.pdf
View BVdb publication page



A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion.

Scientific Reports
Raimondi, Claudio C; Calleja, Veronique V; Ferro, Riccardo R; Fantin, Alessandro A; Riley, Andrew M AM; Potter, Barry V L BV; Brennan, Caroline H CH; Maffucci, Tania T; Larijani, Banafshé B; Falasca, Marco M
Publication Date: 2016-05-20

Variant appearance in text: EGFR: A375M
PubMed Link: 27199173
Variant Present in the following documents:
  • Main text
  • srep26142.pdf
View BVdb publication page



CD82 suppresses CD44 alternative splicing-dependent melanoma metastasis by mediating U2AF2 ubiquitination and degradation.

Oncogene
Zhang, Pu P; Feng, Shan S; Liu, Gentao G; Wang, Heyong H; Fu, Ailing A; Zhu, Huifeng H; Ren, Qiao Q; Wang, Bochu B; Xu, Xingran X; Bai, Huiyuan H; Dong, Cheng C
Publication Date: 2016-09-22

Variant appearance in text: EGFR: A375M
PubMed Link: 27041584
Variant Present in the following documents:
  • Main text
  • nihms-757208.pdf
View BVdb publication page



IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide.

Oncotarget
Ramcharan, Roger R; Aleksic, Tamara T; Kamdoum, Wilfride Petnga WP; Gao, Shan S; Pfister, Sophia X SX; Tanner, Jordan J; Bridges, Esther E; Asher, Ruth R; Watson, Amanda J AJ; Margison, Geoffrey P GP; Woodcock, Mick M; Repapi, Emmanouela E; Li, Ji-Liang JL; Middleton, Mark R MR; Macaulay, Valentine M VM
Publication Date: 2015-11-24

Variant appearance in text: EGFR: A375M
PubMed Link: 26497996
Variant Present in the following documents:
  • Main text
View BVdb publication page



Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death.

International Journal Of Oncology
Shan, Xiu X; Tian, Li Li LL; Zhang, Yu Mei YM; Wang, Xiao Qi XQ; Yan, Qiu Q; Liu, Ji Wei JW
Publication Date: 2015-08

Variant appearance in text: EGFR: A375M
PubMed Link: 26094873
Variant Present in the following documents:
  • Main text
  • ijo-47-02-0701.pdf
View BVdb publication page



Tetraspanins in cell migration.

Cell Adhesion & Migration
Jiang, Xupin X; Zhang, Jiaping J; Huang, Yuesheng Y
Publication Date: 2015

Variant appearance in text: EGFR: A375M
PubMed Link: 26091149
Variant Present in the following documents:
  • Main text
View BVdb publication page



Double-stranded DNA in exosomes: a novel biomarker in cancer detection.

Cell Research
Thakur, Basant Kumar BK; Zhang, Haiying H; Becker, Annette A; Matei, Irina I; Huang, Yujie Y; Costa-Silva, Bruno B; Zheng, Yan Y; Hoshino, Ayuko A; Brazier, Helene H; Xiang, Jenny J; Williams, Caitlin C; Rodriguez-Barrueco, Ruth R; Silva, Jose M JM; Zhang, Weijia W; Hearn, Stephen S; Elemento, Olivier O; Paknejad, Navid N; Manova-Todorova, Katia K; Welte, Karl K; Bromberg, Jacqueline J; Peinado, Héctor H; Lyden, David D
Publication Date: 2014-06

Variant appearance in text: EGFR: A375M
PubMed Link: 24710597
Variant Present in the following documents:
  • cr201444x7.pdf
View BVdb publication page



miR-126&126* restored expressions play a tumor suppressor role by directly regulating ADAM9 and MMP7 in melanoma.

Plos One
Felli, Nadia N; Felicetti, Federica F; Lustri, Anna Maria AM; Errico, M Cristina MC; Bottero, Lisabianca L; Cannistraci, Alessio A; De Feo, Alessandra A; Petrini, Marina M; Pedini, Francesca F; Biffoni, Mauro M; Alvino, Ester E; Negrini, Massimo M; Ferracin, Manuela M; Mattia, Gianfranco G; Carè, Alessandra A
Publication Date: 2013

Variant appearance in text: EGFR: A375M
PubMed Link: 23437250
Variant Present in the following documents:
  • Main text
  • pone.0056824.pdf
View BVdb publication page



Chemoprevention of melanoma.

Advances In Pharmacology (San Diego, Calif.)
Madhunapantula, Subbarao V SV; Robertson, Gavin P GP
Publication Date: 2012

Variant appearance in text: EGFR: A375M
PubMed Link: 22959032
Variant Present in the following documents:
  • Main text
View BVdb publication page



Use of DNA microarray and small animal positron emission tomography in preclinical drug evaluation of RAF265, a novel B-Raf/VEGFR-2 inhibitor.

Neoplasia (New York, N.Y.)
Tseng, Jeffrey R JR; Stuart, Darrin D; Aardalen, Kimberly K; Kaplan, Angelo A; Aziz, Natasha N; Hughes, Nicholas P NP; Gambhir, Sanjiv S SS
Publication Date: 2011-03

Variant appearance in text: EGFR: A375M
PubMed Link: 21390189
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Brn-2 transcription factor links activated BRAF to melanoma proliferation.

Molecular And Cellular Biology
Goodall, Jane J; Wellbrock, Claudia C; Dexter, Timothy J TJ; Roberts, Karen K; Marais, Richard R; Goding, Colin R CR
Publication Date: 2004-04

Variant appearance in text: EGFR: A375M
PubMed Link: 15024080
Variant Present in the following documents:
  • Main text
View BVdb publication page