EGFR c.1324_1325delinsTT ;(p.S442F)

Variant ID: 7-55227857-AG-TT

NM_005228.3(EGFR):c.1324_1325delinsTT;(p.S442F)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


A growing family: adding mutated Erbb4 as a novel cancer target.

Cell Cycle (Georgetown, Tex.)
Rudloff, Udo U; Samuels, Yardena Y
Publication Date: 2010-04-15

Variant appearance in text: EGFR: S442F
PubMed Link: 20404484
Variant Present in the following documents:
  • Main text
View BVdb publication page



Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia.

Behavioral And Brain Functions : Bbf
Benzel, Isabel I; Bansal, Aruna A; Browning, Brian L BL; Galwey, Nicholas W NW; Maycox, Peter R PR; McGinnis, Ralph R; Smart, Devi D; St Clair, David D; Yates, Phillip P; Purvis, Ian I
Publication Date: 2007-06-28

Variant appearance in text: EGFR: S442F
PubMed Link: 17598910
Variant Present in the following documents:
  • 1744-9081-3-31.pdf
View BVdb publication page



Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis.

Bioessays : News And Reviews In Molecular, Cellular And Developmental Biology
Riese, David J DJ; Gallo, Richard M RM; Settleman, Jeffrey J
Publication Date: 2007-06

Variant appearance in text: EGFR: S442F
PubMed Link: 17508401
Variant Present in the following documents:
  • Main text
View BVdb publication page



The epidermal growth factor receptor (EGFR)-S442F mutant displays increased affinity for neuregulin-2beta and agonist-independent coupling with downstream signalling events.

The Biochemical Journal
Gilmore, Jennifer L JL; Gallo, Richard M RM; Riese, David J DJ
Publication Date: 2006-05-15

Variant appearance in text: EGFR: S442F
PubMed Link: 16445385
Variant Present in the following documents:
  • Main text
View BVdb publication page