EGFR c.1420_1421delinsCT ;(p.T474L)

Variant ID: 7-55227953-AC-CT

NM_005228.3(EGFR):c.1420_1421delinsCT;(p.T474L)

This variant was identified in 1 publication

View GRCh38 version.



Variant-Specific Resource Links:
gnomAD v2.1.1
Mutalizer Name Checker
Google
UCSC Genome Browser
ClinVar
dbSNP

Publications:

BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib.

Leukemia
Estupiñán, H Yesid HY; Wang, Qing Q; Berglöf, Anna A; Schaafsma, Gerard C P GCP; Shi, Yuye Y; Zhou, Litao L; Mohammad, Dara K DK; Yu, Liang L; Vihinen, Mauno M; Zain, Rula R; Smith, C I Edvard CIE
Publication Date: 2021-05

Variant appearance in text: EGFR: T474L
PubMed Link: 33526860
Variant Present in the following documents:
  • Main text
  • 41375_2021_Article_1123.pdf
View BVdb publication page