Publications:

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: EGFR: R521K

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3

View BVdb publication page

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Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.

Nature Medicine

Sturm, Dominik D; Capper, David D; Andreiuolo, Felipe F; Gessi, Marco M; Kölsche, Christian C; Reinhardt, Annekathrin A; Sievers, Philipp P; Wefers, Annika K AK; Ebrahimi, Azadeh A; Suwala, Abigail K AK; Gielen, Gerrit H GH; Sill, Martin M; Schrimpf, Daniel D; Stichel, Damian D; Hovestadt, Volker V; Daenekas, Bjarne B; Rode, Agata A; Hamelmann, Stefan S; Previti, Christopher C; Jäger, Natalie N; Buchhalter, Ivo I; Blattner-Johnson, Mirjam M; Jones, Barbara C BC; Warmuth-Metz, Monika M; Bison, Brigitte B; Grund, Kerstin K; Sutter, Christian C; Hirsch, Steffen S; Dikow, Nicola N; Hasselblatt, Martin M; Schüller, Ulrich U; Gerber, Nicolas U NU; White, Christine L CL; Buntine, Molly K MK; Kinross, Kathryn K; Algar, Elizabeth M EM; Hansford, Jordan R JR; Gottardo, Nicholas G NG; Hernáiz Driever, Pablo P; Gnekow, Astrid A; Witt, Olaf O; Müller, Hermann L HL; Calaminus, Gabriele G; Fleischhack, Gudrun G; Kordes, Uwe U; Mynarek, Martin M; Rutkowski, Stefan S; Frühwald, Michael C MC; Kramm, Christof M CM; von Deimling, Andreas A; Pietsch, Torsten T; Sahm, Felix F; Pfister, Stefan M SM; Jones, David T W DTW

Publication Date: 2023-03-16

Variant appearance in text: EGFR: R521K

PubMed Link: 36928815

Variant Present in the following documents:

• 41591_2023_2255_MOESM3_ESM.xlsx, sheet 5

View BVdb publication page

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Identifying potential ligand molecules EGFR mediated TNBC targeting the kinase domain-identification of customized drugs through in silico methods.

Research In Pharmaceutical Sciences

Vyshnavi, Hima H; Namboori, Krishnan K

Publication Date: 2023-04

Variant appearance in text: rs2227983

PubMed Link: 36873279

Variant Present in the following documents:

• Main text
• RPS-18-121.pdf

View BVdb publication page

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Liquid biopsy of cerebrospinal fluid enables selective profiling of glioma molecular subtypes at first clinical presentation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Orzan, Francesca F; De Bacco, Francesca F; Lazzarini, Elisabetta E; Crisafulli, Giovanni G; Gasparini, Alessandra A; Dipasquale, Angelo A; Barault, Ludovic L; Macagno, Marco M; Persico, Pasquale P; Pessina, Federico F; Bono, Beatrice B; Giordano, Laura L; Zeppa, Pietro P; Melcarne, Antonio A; Cassoni, Paola P; Garbossa, Diego D; Santoro, Armando A; Comoglio, Paolo M PM; Indraccolo, Stefano S; Simonelli, Matteo M; Boccaccio, Carla C

Publication Date: 2023-01-17

Variant appearance in text: EGFR: 1562G>A; R521K

PubMed Link: 36648487

Variant Present in the following documents:

• ccr-22-2903_supplementary_data_2_suppds2.xlsx, sheet 2

View BVdb publication page

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Population Pharmacokinetics, Pharmacogenomics, and Adverse Events of Osimertinib and its Two Active Metabolites, AZ5104 and AZ7550, in Japanese Patients with Advanced Non-small Cell Lung Cancer: a Prospective Observational Study.

Investigational New Drugs

Ishikawa, Emi E; Yokoyama, Yuta Y; Chishima, Haruna H; Kasai, Hidefumi H; Kuniyoshi, Ouki O; Kimura, Motonori M; Hakamata, Jun J; Nakada, Hideo H; Suehiro, Naoya N; Nakaya, Naoki N; Nakajima, Hideo H; Ikemura, Shinnosuke S; Kawada, Ichiro I; Yasuda, Hiroyuki H; Terai, Hideki H; Jibiki, Aya A; Kawazoe, Hitoshi H; Soejima, Kenzo K; Muramatsu, Hiroshi H; Suzuki, Sayo S; Nakamura, Tomonori T

Publication Date: 2023-01-13

Variant appearance in text: rs2227983

PubMed Link: 36637703

Variant Present in the following documents:

• Main text
• 10637_2023_Article_1328.pdf

View BVdb publication page

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Gene polymorphisms and prognosis of head and neck squamous cell carcinoma: a systematic review.

Reports Of Practical Oncology And Radiotherapy : Journal Of Greatpoland Cancer Center In Poznan And Polish Society Of Radiation Oncology

Rajabi-Moghaddam, Mahdieh M; Abbaszadeh, Hamid H

Publication Date: 2022

Variant appearance in text: EGFR: R521K

PubMed Link: 36632296

Variant Present in the following documents:

• Main text
• rpor-27-6-1045.pdf

View BVdb publication page

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Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo.

Ejhaem

Safa, Firas F; Rasmussen, Terri T; Lobelle-Rich, Patricia P; Collier, Stephanie S; Milligan, Nicholas N; Schmeig, John J; Schmid, Janet J; Wiewiorowski, Carol C; Totaro, Denise D; Brown, Theresa C TC; Satyavarapu, Ishwarya I; Badoo, Melody M; Ungerleider, Nathan N; Flemington, Erik K EK; Safah, Hana H; Saba, Nakhle S NS

Publication Date: 2022-11

Variant appearance in text: EGFR: R521K; rs2227983

PubMed Link: 36467812

Variant Present in the following documents:

• JHA2-3-1326-s001.xlsx, sheet 1

View BVdb publication page

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Decellularized extracellular matrix as scaffold for cancer organoid cultures of colorectal peritoneal metastases.

Journal Of Molecular Cell Biology

Varinelli, Luca L; Guaglio, Marcello M; Brich, Silvia S; Zanutto, Susanna S; Belfiore, Antonino A; Zanardi, Federica F; Iannelli, Fabio F; Oldani, Amanda A; Costa, Elisa E; Chighizola, Matteo M; Lorenc, Ewelina E; Minardi, Simone P SP; Fortuzzi, Stefano S; Filugelli, Martina M; Garzone, Giovanna G; Pisati, Federica F; Vecchi, Manuela M; Pruneri, Giancarlo G; Kusamura, Shigeki S; Baratti, Dario D; Cattaneo, Laura L; Parazzoli, Dario D; Podestà, Alessandro A; Milione, Massimo M; Deraco, Marcello M; Pierotti, Marco A MA; Gariboldi, Manuela M

Publication Date: 2022-12-02

Variant appearance in text: EGFR: R521K

PubMed Link: 36460033

Variant Present in the following documents:

• mjac064_supplemental_file.pdf

View BVdb publication page

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Pharmacogenetics Role of Genetic Variants in Immune-Related Factors: A Systematic Review Focusing on mCRC.

Pharmaceutics

Scarabel, Lucia L; Bignucolo, Alessia A; Toffoli, Giuseppe G; Cecchin, Erika E; De Mattia, Elena E

Publication Date: 2022-11-15

Variant appearance in text: rs2227983

PubMed Link: 36432658

Variant Present in the following documents:

• Main text
• pharmaceutics-14-02468.pdf

View BVdb publication page

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Preliminary Experience of Liquid Biopsy in Lung Cancer Compared to Conventional Assessment: Light and Shadows.

Journal Of Personalized Medicine

Montella, Marco M; Ciani, Giovanni G; Granata, Vincenza V; Fusco, Roberta R; Grassi, Francesca F; Ronchi, Andrea A; Cozzolino, Immacolata I; Franco, Renato R; Zito Marino, Federica F; Urraro, Fabrizio F; Monti, Riccardo R; Sirica, Roberto R; Savarese, Giovanni G; Chianese, Ugo U; Nebbioso, Angela A; Altucci, Lucia L; Vietri, Maria Teresa MT; Nardone, Valerio V; Reginelli, Alfonso A; Grassi, Roberta R

Publication Date: 2022-11-12

Variant appearance in text: EGFR: Arg521Lys

PubMed Link: 36422072

Variant Present in the following documents:

• Main text
• jpm-12-01896.pdf

View BVdb publication page

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Two independent variants of epidermal growth factor receptor associated with risk of glioma in a Korean population.

Scientific Reports

Baek, In Ki IK; Cheong, Hyun Sub HS; Namgoong, Seok S; Kim, Jeong-Hyun JH; Kang, Seok-Gu SG; Yoon, Seon-Jin SJ; Kim, Se Hoon SH; Chang, Jong Hee JH; Kim, Lyoung Hyo LH; Shin, Hyoung Doo HD

Publication Date: 2022-11-08

Variant appearance in text: EGFR: R521K; rs2227983

PubMed Link: 36347915

Variant Present in the following documents:

• Main text
• 41598_2022_Article_23217.pdf

View BVdb publication page

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Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.

Scientific Reports

Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA

Publication Date: 2022-10-14

Variant appearance in text: EGFR: R521K

PubMed Link: 36241656

Variant Present in the following documents:

• 41598_2022_20939_MOESM4_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM6_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM13_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM2_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM14_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM7_ESM.xlsx, sheet 2

View BVdb publication page

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Lack of Association between Epidermal Growth Factor or Its Receptor and Reflux Esophagitis, Barrett's Esophagus, and Esophageal Adenocarcinoma: A Case-Control Study.

Disease Markers

Deissova, Tereza T; Cvanova, Michaela M; Kala, Zdenek Z; Jiraskova Zakostelska, Zuzana Z; Dolina, Jiri J; Kunovsky, Lumir L; Kroupa, Radek R; Pavlovsky, Zdenek Z; Lipovy, Bretislav B; Danek, Zdenek Z; Izakovicova Holla, Lydie L; Urban, Ondrej O; Navratil, Vit V; Lischke, Robert R; Harustiak, Tomas T; Grolich, Tomas T; Prochazka, Vladimir V; Slaby, Ondrej O; Borilova Linhartova, Petra P

Publication Date: 2022

Variant appearance in text: rs2227983

PubMed Link: 36092955

Variant Present in the following documents:

• DM2022-8790748.pdf

View BVdb publication page

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A genomic deletion encompassing CRYBB2-CRYBB2P1 is responsible for autosomal recessive congenital cataracts.

Human Genome Variation

Irum, Bushra B; Kabir, Firoz F; Shoshany, Nadav N; Khan, Shahid Y SY; Rauf, Bushra B; Naeem, Muhammad Asif MA; Qaiser, Tanveer A TA; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA

Publication Date: 2022-09-08

Variant appearance in text: EGFR: R521K

PubMed Link: 36075891

Variant Present in the following documents:

• 41439_2022_208_MOESM4_ESM.xlsx, sheet 2

View BVdb publication page

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Targeted Next-Generation Sequencing of Thymic Epithelial Tumours Revealed Pathogenic Variants in KIT, ERBB2, KRAS, and TP53 in 30% of Thymic Carcinomas.

Cancers

Szpechcinski, Adam A; Szolkowska, Malgorzata M; Winiarski, Sebastian S; Lechowicz, Urszula U; Wisniewski, Piotr P; Knetki-Wroblewska, Magdalena M

Publication Date: 2022-07-12

Variant appearance in text: EGFR: r521K

PubMed Link: 35884448

Variant Present in the following documents:

• cancers-14-03388.pdf

View BVdb publication page

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Whole exome analysis reveals the genomic profiling related to chemo-resistance in Chinese population with limited-disease small cell lung cancer.

Cancer Medicine

Yu, Jiangyong J; Zhao, Shuangtao S; Su, Zhe Z; Song, Chengli C; Wu, Lihong L; Wang, Jingbo J; Bi, Nan N; Wang, Lvhua L

Publication Date: 2022-06-23

Variant appearance in text: EGFR: R521K

PubMed Link: 35735600

Variant Present in the following documents:

• Main text
• CAM4-12-1035.pdf

View BVdb publication page

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Whole-Exome Sequencing Could Distinguish Primary Pulmonary Squamous Cell Carcinoma From Lung Metastases in Individuals With Cervical Squamous Cell Carcinoma.

Pathology Oncology Research : Por

Li, Lihong L; Song, Qianqian Q; Cao, Dandan D; Jiao, Yuchen Y; Yuan, Guangwen G; Song, Yan Y

Publication Date: 2022

Variant appearance in text: EGFR: 1562G>A; Arg521Lys

PubMed Link: 35645619

Variant Present in the following documents:

• DataSheet1.xlsx, sheet 3

View BVdb publication page

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The Genomic Landscape of Corticotroph Tumors: From Silent Adenomas to ACTH-Secreting Carcinomas.

International Journal Of Molecular Sciences

Andonegui-Elguera, Sergio S; Silva-Román, Gloria G; Peña-Martínez, Eduardo E; Taniguchi-Ponciano, Keiko K; Vela-Patiño, Sandra S; Remba-Shapiro, Ilan I; Gómez-Apo, Erick E; Espinosa-de-Los-Monteros, Ana-Laura AL; Portocarrero-Ortiz, Lesly A LA; Guinto, Gerardo G; Moreno-Jimenez, Sergio S; Chavez-Macias, Laura L; Saucedo, Renata R; Basurto-Acevedo, Lourdes L; Lopez-Felix, Blas B; Gonzalez-Torres, Carolina C; Gaytan-Cervantes, Javier J; Ayala-Sumuano, Jorge T JT; Burak-Leipuner, Andres A; Marrero-Rodríguez, Daniel D; Mercado, Moisés M

Publication Date: 2022-04-27

Variant appearance in text: EGFR: 1562G>A; Arg521Lys; rs2227983

PubMed Link: 35563252

Variant Present in the following documents:

• Main text
• ijms-23-04861.pdf

View BVdb publication page

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A stop-gain mutation in GXYLT1 promotes metastasis of colorectal cancer via the MAPK pathway.

Cell Death & Disease

Peng, Lin L; Zhao, Min M; Liu, Tianqi T; Chen, Jiangbo J; Gao, Pin P; Chen, Lei L; Xing, Pu P; Wang, Zaozao Z; Di, Jiabo J; Xu, Qiang Q; Qu, Hong H; Jiang, Beihai B; Su, Xiangqian X

Publication Date: 2022-04-22

Variant appearance in text: EGFR: R521K

PubMed Link: 35459861

Variant Present in the following documents:

• 41419_2022_4844_MOESM4_ESM.xlsx, sheet 3

View BVdb publication page

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EGFR Mutations in Head and Neck Squamous Cell Carcinoma.

International Journal Of Molecular Sciences

Nair, Sindhu S; Bonner, James A JA; Bredel, Markus M

Publication Date: 2022-03-30

Variant appearance in text: EGFR: R521K

PubMed Link: 35409179

Variant Present in the following documents:

• Main text
• ijms-23-03818.pdf

View BVdb publication page

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: R521K

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

View BVdb publication page

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p16INK4A-deficiency predicts response to combined HER2 and CDK4/6 inhibition in HER2+ breast cancer brain metastases.

Nature Communications

Ni, Jing J; Kabraji, Sheheryar S; Xie, Shaozhen S; Wang, Yanzhi Y; Pan, Peichen P; He, Xiaofang X; Liu, Zongming Z; Leone, Jose Palbo JP; Long, Henry W HW; Brown, Myles A MA; Winer, Eric P EP; Dillon, Deborah A R DAR; Lin, Nancy U NU; Zhao, Jean J JJ

Publication Date: 2022-03-18

Variant appearance in text: EGFR: R521K

PubMed Link: 35304445

Variant Present in the following documents:

• 41467_2022_29081_MOESM3_ESM.xlsx, sheet 16

View BVdb publication page

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Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies.

Journal Of Cancer Research And Clinical Oncology

Kleo, Karsten K; Jovanovic, Vladimir M VM; Arndold, Alexander A; Lehmann, Annika A; Lammert, Hedwig H; Berg, Erika E; Harloff, Hannah H; Treese, Christoph C; Hummel, Michael M; Daum, Severin S

Publication Date: 2022-03-05

Variant appearance in text: EGFR: 1562G>A; rs2227983

PubMed Link: 35246724

Variant Present in the following documents:

• 432_2022_3944_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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SMAP is a pipeline for sample matching in proteogenomics.

Nature Communications

Li, Ling L; Niu, Mingming M; Erickson, Alyssa A; Luo, Jie J; Rowbotham, Kincaid K; Guo, Kai K; Huang, He H; Li, Yuxin Y; Jiang, Yi Y; Hur, Junguk J; Liu, Chunyu C; Peng, Junmin J; Wang, Xusheng X

Publication Date: 2022-02-08

Variant appearance in text: EGFR: R521K

PubMed Link: 35136070

Variant Present in the following documents:

• 41467_2022_28411_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Turing miRNA into infinite coordination supermolecule: a general and enabling nanoengineering strategy for resurrecting nuclear acid therapeutics.

Journal Of Nanobiotechnology

Li, Liya L; He, Wangxiao W; You, Weiming W; Yan, Jin J; Liu, Wenjia W

Publication Date: 2022-01-04

Variant appearance in text: EGFR: R521K

PubMed Link: 34983557

Variant Present in the following documents:

• Main text
• 12951_2021_Article_1212.pdf

View BVdb publication page

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Turing miRNA into infinite coordination supermolecule: a general and enabling nanoengineering strategy for resurrecting nuclear acid therapeutics.

Journal Of Nanobiotechnology

Li, Liya L; He, Wangxiao W; You, Weiming W; Yan, Jin J; Liu, Wenjia W

Publication Date: 2022-01-04

Variant appearance in text: EGFR: R521K

PubMed Link: 34983557

Variant Present in the following documents:

• Main text
• 12951_2021_Article_1212.pdf

View BVdb publication page

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Validation of Genetic Markers Associated with Survival in Colorectal Cancer Patients Treated with Oxaliplatin-Based Chemotherapy.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology

Park, Hanla A HA; Seibold, Petra P; Edelmann, Dominic D; Benner, Axel A; Canzian, Federico F; Alwers, Elizabeth E; Jansen, Lina L; Schneider, Martin M; Hoffmeister, Michael M; Brenner, Hermann H; Chang-Claude, Jenny J

Publication Date: 2022-02

Variant appearance in text: rs2227983

PubMed Link: 34862210

Variant Present in the following documents:

• Main text
• 268527_2_supp_7525223_r2sknd.pdf
• 352.pdf

View BVdb publication page

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Epstein Barr virus-positive B-cell lymphoma is highly vulnerable to MDM2 inhibitors in vivo.

Blood Advances

Zhang, Xiaoshan X; Zhang, Ran R; Ren, Chenghui C; Xu, Yi Y; Wu, Shuhong S; Meng, Carrie C; Pataer, Apar A; Song, Xingzhi X; Zhang, Jianhua J; Yao, Yixin Y; He, Hua H; Chen, Huiqin H; Ma, Wencai W; Wang, Jing J; Meric-Bernstam, Funda F; Champlin, Richard E RE; Heymach, John V JV; Rooney, Cliona M CM; Swisher, Stephen G SG; Vaporciyan, Ara A AA; Roth, Jack A JA; You, M James MJ; Wang, Michael M; Fang, Bingliang B

Publication Date: 2022-02-08

Variant appearance in text: EGFR: R521K

PubMed Link: 34861697

Variant Present in the following documents:

• advancesADV2021006156-suppl2.xlsx, sheet 2

View BVdb publication page

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Multiomics Landscape Uncovers the Molecular Mechanism of the Malignant Evolution of Lung Adenocarcinoma Cells to Chronic Low Dose Cadmium Exposure.

Frontiers In Oncology

Dai, Shun-Dong SD; Wang, Shuang S; Qin, Ya-Nan YN; Zhu, Jin-Chao JC

Publication Date: 2021

Variant appearance in text: EGFR: R521K

PubMed Link: 34858801

Variant Present in the following documents:

• Table_1.xls, sheet 1

View BVdb publication page

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Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer.

Translational Oncology

Metzenmacher, Martin M; Hegedüs, Balazs B; Forster, Jan J; Schramm, Alexander A; Horn, Peter A PA; Klein, Christoph A CA; Bielefeld, Nicola N; Ploenes, Till T; Aigner, Clemens C; Theegarten, Dirk D; Schildhaus, Hans-Ulrich HU; Siveke, Jens T JT; Schuler, Martin M; Lueong, Smiths S SS

Publication Date: 2022-01

Variant appearance in text: EGFR: 1562G>A; Arg521Lys; rs2227983

PubMed Link: 34800919

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

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Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer.

Translational Oncology

Metzenmacher, Martin M; Hegedüs, Balazs B; Forster, Jan J; Schramm, Alexander A; Horn, Peter A PA; Klein, Christoph A CA; Bielefeld, Nicola N; Ploenes, Till T; Aigner, Clemens C; Theegarten, Dirk D; Schildhaus, Hans-Ulrich HU; Siveke, Jens T JT; Schuler, Martin M; Lueong, Smiths S SS

Publication Date: 2021-11-17

Variant appearance in text: EGFR: 1562G>A; Arg521Lys; rs2227983

PubMed Link: 34800919

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

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Proteogenomics Reveals Perturbed Signaling Networks in Malignant Melanoma Cells Resistant to BRAF Inhibition.

Molecular & Cellular Proteomics : Mcp

Schmitt, Marisa M; Sinnberg, Tobias T; Bratl, Katrin K; Zittlau, Katharina K; Garbe, Claus C; Macek, Boris B; Nalpas, Nicolas C NC

Publication Date: 2021-10-19

Variant appearance in text: EGFR: R521K

PubMed Link: 34673281

Variant Present in the following documents:

• mmc2.xlsx, sheet 11
• mmc2.xlsx, sheet 3
• mmc2.xlsx, sheet 4
• mmc2.xlsx, sheet 6
• mmc2.xlsx, sheet 9

View BVdb publication page

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Proteogenomics Reveals Perturbed Signaling Networks in Malignant Melanoma Cells Resistant to BRAF Inhibition.

Molecular & Cellular Proteomics : Mcp

Schmitt, Marisa M; Sinnberg, Tobias T; Bratl, Katrin K; Zittlau, Katharina K; Garbe, Claus C; Macek, Boris B; Nalpas, Nicolas C NC

Publication Date: 2021

Variant appearance in text: EGFR: R521K

PubMed Link: 34673281

Variant Present in the following documents:

• mmc2.xlsx, sheet 3
• mmc2.xlsx, sheet 9
• mmc2.xlsx, sheet 6
• mmc2.xlsx, sheet 4
• mmc2.xlsx, sheet 11

View BVdb publication page

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Establishment and characterization of novel highly aggressive HER2‑positive and triple‑negative breast cancer cell lines.

Oncology Reports

Thongchot, Suyanee S; Jamjuntra, Pranisa P; Prasopsiri, Jaturawitt J; Thuwajit, Peti P; Sawasdee, Nunghathai N; Poungvarin, Naravat N; Warnnissorn, Malee M; Sa-Nguanraksa, Doonyapat D; O-Charoenrat, Pornchai P; Yenchitsomanus, Pa-Thai PT; Thuwajit, Chanitra C

Publication Date: 2021-12

Variant appearance in text: EGFR: 1562G>A; R521K

PubMed Link: 34651665

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Investigation of Associations between TP53 rs1042522, BBC3 rs2032809, CCND1 rs9344, EGFR rs2227983 Polymorphisms and Breast Cancer Phenotype and Prognosis.

Diagnostics (Basel, Switzerland)

Bekampytė, Justina J; Bartnykaitė, Agnė A; Savukaitytė, Aistė A; Ugenskienė, Rasa R; Korobeinikova, Erika E; Gudaitienė, Jurgita J; Juozaitytė, Elona E

Publication Date: 2021-08-05

Variant appearance in text: EGFR: R521K; rs2227983

PubMed Link: 34441352

Variant Present in the following documents:

• Main text
• diagnostics-11-01419.pdf

View BVdb publication page

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Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines

Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á

Publication Date: 2021-07-28

Variant appearance in text: EGFR: R521K

PubMed Link: 34440110

Variant Present in the following documents:

• Main text

View BVdb publication page

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High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs.

Plos Genetics

Akhtari, Farida S FS; Green, Adrian J AJ; Small, George W GW; Havener, Tammy M TM; House, John S JS; Roell, Kyle R KR; Reif, David M DM; McLeod, Howard L HL; Wiltshire, Timothy T; Motsinger-Reif, Alison A AA

Publication Date: 2021-08

Variant appearance in text: rs2227983

PubMed Link: 34437536

Variant Present in the following documents:

• Main text

View BVdb publication page

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Circulating tumor DNA sequencing in colorectal cancer patients treated with first-line chemotherapy with anti-EGFR.

Scientific Reports

Lim, Yoojoo Y; Kim, Sheehyun S; Kang, Jun-Kyu JK; Kim, Hwang-Phill HP; Jang, Hoon H; Han, Hyojun H; Kim, Hyoki H; Kim, Min Jung MJ; Lee, Kyung-Hun KH; Ryoo, Seung-Bum SB; Park, Ji Won JW; Jeong, Seung-Yong SY; Park, Kyu Joo KJ; Kang, Gyeong Hoon GH; Han, Sae-Won SW; Kim, Tae-You TY

Publication Date: 2021-08-11

Variant appearance in text: EGFR: 1562G>A; Arg521Lys; rs2227983

PubMed Link: 34381078

Variant Present in the following documents:

• 41598_2021_95345_MOESM5_ESM.xlsx, sheet 1
• 41598_2021_95345_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer.

Journal For Immunotherapy Of Cancer

Stein, Alexander A; Simnica, Donjete D; Schultheiß, Christoph C; Scholz, Rebekka R; Tintelnot, Joseph J; Gökkurt, Eray E; von Wenserski, Lisa L; Willscher, Edith E; Paschold, Lisa L; Sauer, Markus M; Lorenzen, Sylvie S; Riera-Knorrenschild, Jorge J; Depenbusch, Reinhard R; Ettrich, Thomas J TJ; Dörfel, Steffen S; Al-Batran, Salah-Eddin SE; Karthaus, Meinolf M; Pelzer, Uwe U; Waberer, Lisa L; Hinke, Axel A; Bauer, Marcus M; Massa, Chiara C; Seliger, Barbara B; Wickenhauser, Claudia C; Bokemeyer, Carsten C; Hegewisch-Becker, Susanna S; Binder, Mascha M

Publication Date: 2021-07

Variant appearance in text: EGFR: 1562G>A; Arg521Lys; rs2227983

PubMed Link: 34315821

Variant Present in the following documents:

• jitc-2021-002844supp002.xlsx, sheet 1

View BVdb publication page

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EGFR Alterations Influence the Cetuximab Treatment Response and c-MET Tyrosine-Kinase Inhibitor Sensitivity in Experimental Head and Neck Squamous Cell Carcinomas.

Pathology Oncology Research : Por

Nelhűbel, Györgyi A GA; Cserepes, Mihály M; Szabó, Balázs B; Türk, Dóra D; Kárpáti, Adél A; Kenessey, István I; Rásó, Erzsébet E; Barbai, Tamás T; Hegedűs, Zita Z; László, Viktória V; Szokol, Bálint B; Dobos, Judit J; Őrfi, László L; Tóvári, József J

Publication Date: 2021

Variant appearance in text: EGFR: R521K

PubMed Link: 34257586

Variant Present in the following documents:

• Main text
• pore-27-620256.pdf

View BVdb publication page

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Comprehensive molecular profiling of pulmonary pleomorphic carcinoma.

Npj Precision Oncology

Nagano, Masaaki M; Kohsaka, Shinji S; Hayashi, Takuo T; Ueno, Toshihide T; Kojima, Shinya S; Shinozaki-Ushiku, Aya A; Morita, Shigeki S; Tsuda, Masumi M; Tanaka, Shinya S; Shinohara, Toshiya T; Omori, Yuko Y; Sugaya, Fumiko F; Kato, Hiroaki H; Narita, Yoshiaki Y; Nakajima, Jun J; Suzuki, Kenji K; Takamochi, Kazuya K; Mano, Hiroyuki H

Publication Date: 2021-06-22

Variant appearance in text: EGFR: 1562G>A; Arg521Lys

PubMed Link: 34158601

Variant Present in the following documents:

• 41698_2021_201_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Polymorphisms in EGFR Gene Predict Clinical Outcome in Unresectable Non-Small Cell Lung Cancer Treated with Radiotherapy and Platinum-Based Chemoradiotherapy.

International Journal Of Molecular Sciences

Butkiewicz, Dorota D; Krześniak, Małgorzata M; Gdowicz-Kłosok, Agnieszka A; Giglok, Monika M; Marszałek-Zeńczak, Małgorzata M; Suwiński, Rafał R

Publication Date: 2021-05-25

Variant appearance in text: EGFR: R521K; rs2227983

PubMed Link: 34070597

Variant Present in the following documents:

• Main text

View BVdb publication page

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Case Report: A Variant Non-ketotic Hyperglycinemia With GLRX5 Mutations: Manifestation of Deficiency of Activities of the Respiratory Chain Enzymes.

Frontiers In Genetics

Feng, Wei-Xing WX; Zhuo, Xiu-Wei XW; Liu, Zhi-Mei ZM; Li, Jiu-Wei JW; Zhang, Wei-Hua WH; Wu, Yun Y; Han, Tong-Li TL; Fang, Fang F

Publication Date: 2021

Variant appearance in text: EGFR: 1562G>A; R521K; rs2227983

PubMed Link: 34054912

Variant Present in the following documents:

• Table_2.xlsx, sheet 1

View BVdb publication page

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Genetic analysis of sinonasal undifferentiated carcinoma discovers recurrent SWI/SNF alterations and a novel PGAP3-SRPK1 fusion gene.

Bmc Cancer

Heft Neal, Molly E ME; Birkeland, Andrew C AC; Bhangale, Apurva D AD; Zhai, Jingyi J; Kulkarni, Aditi A; Foltin, Susan K SK; Jewell, Brittany M BM; Ludwig, Megan L ML; Pinatti, Lisa L; Jiang, Hui H; McHugh, Jonathan B JB; Marentette, Lawence L; McKean, Erin L EL; Brenner, J Chad JC

Publication Date: 2021-05-29

Variant appearance in text: EGFR: 1562G>A; Arg521Lys; rs2227983

PubMed Link: 34051734

Variant Present in the following documents:

• 12885_2021_8370_MOESM15_ESM.xlsx, sheet 1

View BVdb publication page

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Concomitant Mutations G12D and G13D on the Exon 2 of the KRAS Gene: Two Cases of Women with Colon Adenocarcinoma.

Diagnostics (Basel, Switzerland)

De Falco, Elena E; Pacini, Luca L; Bastianelli, Daniela D; Spinelli, Gian Paolo GP; Spoto, Chiara C; Veltri, Enzo E; Calogero, Antonella A

Publication Date: 2021-04-06

Variant appearance in text: EGFR: 1562G>A; R521K

PubMed Link: 33917572

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic variants of the EGFR ligand-binding domain and their association with structural alterations in Arab cancer patients.

Bmc Research Notes

Marzouq, Maryam M; Nairouz, Ali A; Ben Khalaf, Noureddine N; Bourguiba-Hachemi, Sonia S; Quaddorah, Raed R; Ashoor, Dana D; Fathallah, M Dahmani MD

Publication Date: 2021-04-19

Variant appearance in text: EGFR: R521K; rs2227983

PubMed Link: 33874989

Variant Present in the following documents:

• Main text
• 13104_2021_Article_5559.pdf
• 13104_2021_5559_MOESM2_ESM.pdf
• 13104_2021_5559_MOESM4_ESM.pdf

View BVdb publication page

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Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity.

Npj Precision Oncology

Yoshizawa, Takahiro T; Uchibori, Ken K; Araki, Mitsugu M; Matsumoto, Shigeyuki S; Ma, Biao B; Kanada, Ryo R; Seto, Yosuke Y; Oh-Hara, Tomoko T; Koike, Sumie S; Ariyasu, Ryo R; Kitazono, Satoru S; Ninomiya, Hironori H; Takeuchi, Kengo K; Yanagitani, Noriko N; Takagi, Satoshi S; Kishi, Kazuma K; Fujita, Naoya N; Okuno, Yasushi Y; Nishio, Makoto M; Katayama, Ryohei R

Publication Date: 2021-04-16

Variant appearance in text: EGFR: 1562G>A; Arg521Lys; rs2227983

PubMed Link: 33863983

Variant Present in the following documents:

• 41698_2021_170_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Gene variants associated with acne vulgaris presentation and severity: a systematic review and meta-analysis.

Bmc Medical Genomics

Heng, Anna Hwee Sing AHS; Say, Yee-How YH; Sio, Yang Yie YY; Ng, Yu Ting YT; Chew, Fook Tim FT

Publication Date: 2021-04-13

Variant appearance in text: EGFR: R521K; rs2227983

PubMed Link: 33849530

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.

Communications Biology

Nagasawa, Satoi S; Kuze, Yuta Y; Maeda, Ichiro I; Kojima, Yasuyuki Y; Motoyoshi, Ai A; Onishi, Tatsuya T; Iwatani, Tsuguo T; Yokoe, Takamichi T; Koike, Junki J; Chosokabe, Motohiro M; Kubota, Manabu M; Seino, Hibiki H; Suzuki, Ayako A; Seki, Masahide M; Tsuchihara, Katsuya K; Inoue, Eisuke E; Tsugawa, Koichiro K; Ohta, Tomohiko T; Suzuki, Yutaka Y

Publication Date: 2021-04-01

Variant appearance in text: EGFR: R521K; rs2227983

PubMed Link: 33795819

Variant Present in the following documents:

• 42003_2021_1959_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Disseminated Talaromyces marneffei Infection in a Non-HIV Infant With a Homozygous Private Variant of RELB.

Frontiers In Cellular And Infection Microbiology

Ding, Xiaofang X; Huang, Han H; Zhong, Lili L; Chen, Min M; Peng, Fang F; Zhang, Bing B; Cui, Xinyu X; Yang, Xiu-An XA

Publication Date: 2021

Variant appearance in text: EGFR: Arg521Lys; rs2227983

PubMed Link: 33791233

Variant Present in the following documents:

• Table_2.xlsx, sheet 1

View BVdb publication page

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Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools.

Plos One

Sebate, Boiketlo B; Cuttler, Katelyn K; Cloete, Ruben R; Britz, Marcell M; Christoffels, Alan A; Williams, Monique M; Carr, Jonathan J; Bardien, Soraya S

Publication Date: 2021

Variant appearance in text: EGFR: 1562G>A; R521K; rs2227983

PubMed Link: 33770142

Variant Present in the following documents:

• pone.0249324.s003.xlsx, sheet 3

View BVdb publication page

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Azathioprine antagonizes aberrantly elevated lipid metabolism and induces apoptosis in glioblastoma.

Iscience

Nam, Hye Jin HJ; Kim, Young Eun YE; Moon, Byoung-San BS; Kim, Hyun Young HY; Jung, Daeyoung D; Choi, Seungho S; Jang, Jeong Woon JW; Nam, Do-Hyun DH; Cho, Heeyeong H

Publication Date: 2021-03-19

Variant appearance in text: EGFR: R521K

PubMed Link: 33748720

Variant Present in the following documents:

• Main text

View BVdb publication page

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