EGFR c.1793G>T ;(p.G598V)

Variant ID: 7-55233043-G-T

NM_005228.3(EGFR):c.1793G>T;(p.G598V)

This variant was identified in 144 publications

View GRCh38 version.




Publications:


P16 immunohistochemistry is a sensitive and specific surrogate marker for CDKN2A homozygous deletion in gliomas.

Acta Neuropathologica Communications
Vij, Meenakshi M; Cho, Benjamin B BB; Yokoda, Raquel T RT; Rashidipour, Omid O; Umphlett, Melissa M; Richardson, Timothy E TE; Tsankova, Nadejda M NM
Publication Date: 2023-05-03

Variant appearance in text: EGFR: G598V
PubMed Link: 37138345
Variant Present in the following documents:
  • 40478_2023_1573_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: EGFR: G598V
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 4
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 2
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: EGFR: 1793G>T; Gly598Val
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan.

Cancer Science
Kage, Hidenori H; Shinozaki-Ushiku, Aya A; Ishigaki, Kazunaga K; Sato, Yusuke Y; Tanabe, Masahiko M; Tanaka, Shota S; Tanikawa, Michihiro M; Watanabe, Kousuke K; Kato, Shingo S; Akagi, Kiwamu K; Uchino, Keita K; Mitani, Kinuko K; Takahashi, Shunji S; Miura, Yuji Y; Ikeda, Sadakatsu S; Kojima, Yasushi Y; Watanabe, Kiyotaka K; Mochizuki, Hitoshi H; Yamaguchi, Hironori H; Kawazoe, Yoshimasa Y; Kashiwabara, Kosuke K; Kohsaka, Shinji S; Tatsuno, Kenji K; Ushiku, Tetsuo T; Ohe, Kazuhiko K; Yatomi, Yutaka Y; Seto, Yasuyuki Y; Aburatani, Hiroyuki H; Mano, Hiroyuki H; Miyagawa, Kiyoshi K; Oda, Katsutoshi K
Publication Date: 2023-01-05

Variant appearance in text: EGFR: 1793G>T; G598V
PubMed Link: 36601953
Variant Present in the following documents:
  • CAS-114-1710-s001.xlsx, sheet 1
View BVdb publication page



Impact of EGFRA289T/V mutation on relapse pattern in glioblastoma.

Esmo Open
Noeuveglise, A A; Sarafan-Vasseur, N N; Beaussire, L L; Marguet, F F; Modzelewski, R R; Hanzen, C C; Alexandru, C C; Magne, N N; Langlois, O O; Di Fiore, F F; Clatot, F F; Thureau, S S; Fontanilles, M M
Publication Date: 2022-12-22

Variant appearance in text: EGFR: G598V
PubMed Link: 36566697
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics
G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A
Publication Date: 2022

Variant appearance in text: EGFR: G598V
PubMed Link: 36561320
Variant Present in the following documents:
  • Table3.xlsx, sheet 1
  • Table2.xlsx, sheet 4
View BVdb publication page



An integrative approach for exploring the nature of fibroepithelial neoplasms.

British Journal Of Cancer
Yun, Jihui J; Heo, Woohang W; Lee, Eun-Shin ES; Na, Deukchae D; Kang, Wonyoung W; Kang, Jinjoo J; Chae, Jeesoo J; Lee, Dakyung D; Lee, Woochan W; Hwang, Jinha J; Yoo, Tae-Kyung TK; Hong, Bok Sil BS; Son, Hye-Youn HY; Noh, Dong-Young DY; Lee, Charles C; Moon, Hyeong-Gon HG; Kim, Jong-Il JI
Publication Date: 2022-12-16

Variant appearance in text: EGFR: G598V
PubMed Link: 36522480
Variant Present in the following documents:
  • 41416_2022_2064_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Concordance Between Recommendations From Multidisciplinary Molecular Tumor Boards and Central Consensus for Cancer Treatment in Japan.

Jama Network Open
Naito, Yoichi Y; Sunami, Kuniko K; Kage, Hidenori H; Komine, Keigo K; Amano, Toraji T; Imai, Mitsuho M; Koyama, Takafumi T; Ennishi, Daisuke D; Kanai, Masashi M; Kenmotsu, Hirotsugu H; Maeda, Takahiro T; Morita, Sachi S; Sakai, Daisuke D; Watanabe, Kousuke K; Shirota, Hidekazu H; Kinoshita, Ichiro I; Yoshioka, Masashiro M; Mamesaya, Nobuaki N; Ito, Mamoru M; Kohsaka, Shinji S; Saigusa, Yusuke Y; Yamamoto, Kouji K; Hirata, Makoto M; Tsuchihara, Katsuya K; Yoshino, Takayuki T
Publication Date: 2022-12-01

Variant appearance in text: EGFR: G598V
PubMed Link: 36469316
Variant Present in the following documents:
  • jamanetwopen-e2245081-s001.pdf
View BVdb publication page



Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications
Boström, Martin M; Larsson, Erik E
Publication Date: 2022-11-17

Variant appearance in text: EGFR: G598V
PubMed Link: 36396655
Variant Present in the following documents:
  • 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Improvements in Quality Control and Library Preparation for Targeted Sequencing Allowed Detection of Potentially Pathogenic Alterations in Circulating Cell-Free DNA Derived from Plasma of Brain Tumor Patients.

Cancers
Szadkowska, Paulina P; Roura, Adria-Jaume AJ; Wojtas, Bartosz B; Wojnicki, Kamil K; Licholai, Sabina S; Waller, Tomasz T; Gubala, Tomasz T; Zukowski, Kacper K; Karpeta, Michal M; Wilkus, Kinga K; Kaspera, Wojciech W; Nawrocki, Sergiusz S; Kaminska, Bozena B
Publication Date: 2022-08-12

Variant appearance in text: rs139236063
PubMed Link: 36010895
Variant Present in the following documents:
  • cancers-14-03902.pdf
View BVdb publication page



Identification of potential targets of the curcumin analog CCA-1.1 for glioblastoma treatment : integrated computational analysis and in vitro study.

Scientific Reports
Hermawan, Adam A; Wulandari, Febri F; Hanif, Naufa N; Utomo, Rohmad Yudi RY; Jenie, Riris Istighfari RI; Ikawati, Muthi M; Tafrihani, Ahmad Syauqy AS
Publication Date: 2022-08-17

Variant appearance in text: EGFR: 1793G>T; G598V
PubMed Link: 35977996
Variant Present in the following documents:
  • 41598_2022_18348_MOESM3_ESM.xlsx, sheet 6
View BVdb publication page



Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma.

Nature Communications
Coy, Shannon S; Wang, Shu S; Stopka, Sylwia A SA; Lin, Jia-Ren JR; Yapp, Clarence C; Ritch, Cecily C CC; Salhi, Lisa L; Baker, Gregory J GJ; Rashid, Rumana R; Baquer, Gerard G; Regan, Michael M; Khadka, Prasidda P; Cole, Kristina A KA; Hwang, Jaeho J; Wen, Patrick Y PY; Bandopadhayay, Pratiti P; Santi, Mariarita M; De Raedt, Thomas T; Ligon, Keith L KL; Agar, Nathalie Y R NYR; Sorger, Peter K PK; Touat, Mehdi M; Santagata, Sandro S
Publication Date: 2022-08-16

Variant appearance in text: EGFR: G598V
PubMed Link: 35973991
Variant Present in the following documents:
  • 41467_2022_32430_MOESM17_ESM.xlsx, sheet 12
View BVdb publication page



S645C Point Mutation Suppresses Degradation of EGFR to Promote Progression of Glioblastoma.

Frontiers In Oncology
Huang, Wenda W; Zou, Ling L; Hao, Zhaonian Z; Wang, Baofeng B; Mao, Feng F; Duan, Qiuhong Q; Guo, Dongsheng D
Publication Date: 2022

Variant appearance in text: EGFR: G598V
PubMed Link: 35814475
Variant Present in the following documents:
  • Main text
  • fonc-12-904383.pdf
View BVdb publication page



Distribution and favorable prognostic implication of genomic EGFR alterations in IDH-wildtype glioblastoma.

Cancer Medicine
Higa, Nayuta N; Akahane, Toshiaki T; Hamada, Taiji T; Yonezawa, Hajime H; Uchida, Hiroyuki H; Makino, Ryutaro R; Watanabe, Shoji S; Takajo, Tomoko T; Yokoyama, Seiya S; Kirishima, Mari M; Matsuo, Kei K; Fujio, Shingo S; Hanaya, Ryosuke R; Tanimoto, Akihide A; Yoshimoto, Koji K
Publication Date: 2022-06-13

Variant appearance in text: EGFR: G598V
PubMed Link: 35695190
Variant Present in the following documents:
  • Main text
  • CAM4-12-49.pdf
View BVdb publication page



Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging
Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M
Publication Date: 2022-05-25

Variant appearance in text: EGFR: 1793G>T; G598V
PubMed Link: 35613927
Variant Present in the following documents:
  • aging-14-204101-s004.xlsx, sheet 1
View BVdb publication page



Fundamental immune-oncogenicity trade-offs define driver mutation fitness.

Nature
Hoyos, David D; Zappasodi, Roberta R; Schulze, Isabell I; Sethna, Zachary Z; de Andrade, Kelvin César KC; Bajorin, Dean F DF; Bandlamudi, Chaitanya C; Callahan, Margaret K MK; Funt, Samuel A SA; Hadrup, Sine R SR; Holm, Jeppe S JS; Rosenberg, Jonathan E JE; Shah, Sohrab P SP; Vázquez-García, Ignacio I; Weigelt, Britta B; Wu, Michelle M; Zamarin, Dmitriy D; Campitelli, Laura F LF; Osborne, Edward J EJ; Klinger, Mark M; Robins, Harlan S HS; Khincha, Payal P PP; Savage, Sharon A SA; Balachandran, Vinod P VP; Wolchok, Jedd D JD; Hellmann, Matthew D MD; Merghoub, Taha T; Levine, Arnold J AJ; Łuksza, Marta M; Greenbaum, Benjamin D BD
Publication Date: 2022-06

Variant appearance in text: EGFR: G598V
PubMed Link: 35545680
Variant Present in the following documents:
  • 41586_2022_4696_MOESM1_ESM.pdf
View BVdb publication page



Genomic Analysis of Tumors from Patients with Glioblastoma with Long-Term Response to Afatinib.

Oncotargets And Therapy
Owen, Scott S; Alken, Scheryll S; Alshami, Jad J; Guiot, Marie-Christine MC; Kavan, Petr P; Reardon, David A DA; Muanza, Thierry T; Gibson, Neil N; Pemberton, Karine K; Solca, Flavio F; Cseh, Agnieszka A; Saran, Frank F
Publication Date: 2022

Variant appearance in text: EGFR: 1793G>T; G598V
PubMed Link: 35422631
Variant Present in the following documents:
  • Main text
  • ott-15-367.pdf
View BVdb publication page



Prospective genomically guided identification of "early/evolving" and "undersampled" IDH-wildtype glioblastoma leads to improved clinical outcomes.

Neuro-Oncology
Zhang, Yalan Y; Lucas, Calixto-Hope G CG; Young, Jacob S JS; Morshed, Ramin A RA; McCoy, Lucie L; Oberheim Bush, Nancy Ann NA; Taylor, Jennie W JW; Daras, Mariza M; Butowski, Nicholas A NA; Villanueva-Meyer, Javier E JE; Cha, Soonmee S; Wrensch, Margaret M; Wiencke, John K JK; Lee, Julieann C JC; Pekmezci, Melike M; Phillips, Joanna J JJ; Perry, Arie A; Bollen, Andrew W AW; Aghi, Manish K MK; Theodosopoulos, Philip P; Chang, Edward F EF; Hervey-Jumper, Shawn L SL; Berger, Mitchel S MS; Clarke, Jennifer L JL; Chang, Susan M SM; Molinaro, Annette M AM; Solomon, David A DA
Publication Date: 2022-10-03

Variant appearance in text: EGFR: 1793G>T; G598V
PubMed Link: 35395677
Variant Present in the following documents:
  • noac089_suppl_supplementary_tables_s1-s11.xlsx, sheet 5
View BVdb publication page



Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-04

Variant appearance in text: EGFR: G598V
PubMed Link: 35304574
Variant Present in the following documents:
  • 41388_2022_Article_2263.pdf
View BVdb publication page



Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research
Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL
Publication Date: 2022-05

Variant appearance in text: EGFR: G598V
PubMed Link: 35229492
Variant Present in the following documents:
  • PCMR-35-369-s003.xlsx, sheet 12
View BVdb publication page



The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer
Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J
Publication Date: 2022-02

Variant appearance in text: EGFR: Gly598Val
PubMed Link: 35221333
Variant Present in the following documents:
  • 43018_2022_332_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Association of differential expression of immunoregulatory molecules and presence of targetable mutations may inform rational design of clinical trials.

Esmo Open
Szeto, C W CW; Kurzrock, R R; Kato, S S; Goloubev, A A; Veerapaneni, S S; Preble, A A; Reddy, S K SK; Adashek, J J JJ
Publication Date: 2022-02

Variant appearance in text: EGFR: G598V
PubMed Link: 35158206
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Landscape of driver gene events, biomarkers, and druggable targets identified by whole-genome sequencing of glioblastomas.

Neuro-Oncology Advances
van de Geer, Wesley S WS; Hoogstrate, Youri Y; Draaisma, Kaspar K; Robe, Pierre A PA; Bins, Sander S; Mathijssen, Ron H J RHJ; French, Pim P; van de Werken, Harmen J G HJG; de Vos, Filip Y F FYF
Publication Date: 2022

Variant appearance in text: EGFR: Gly598Val
PubMed Link: 35047820
Variant Present in the following documents:
  • vdab177_suppl_supplementary_data.xlsx, sheet 6
View BVdb publication page



Ultrasensitive analysis of genetic instability related to chemical exposure.

Journal Of Applied Genetics
Domoradzki, Tomasz T; Grochowski, Piotr P; Jaśkiewicz, Anna A; Pająk, Beata B
Publication Date: 2022-05

Variant appearance in text: EGFR: G598V
PubMed Link: 34967917
Variant Present in the following documents:
  • Main text
  • 13353_2021_Article_677.pdf
View BVdb publication page



Integrating real-time in vivo tumour genomes for longitudinal analysis and management of glioma recurrence.

Clinical And Translational Medicine
Sheng, Zhiyuan Z; Yu, Jinliang J; Deng, Kaiyuan K; Bu, Yage Y; Wu, Shuang S; Xu, Sensen S; Gao, Yushuai Y; Zhang, Qianqian Q; Yan, Zhaoyue Z; Bu, Chaojie C; Chen, Zhongcan Z; Gu, Jianjun J; Jia, Yan Y; Gao, Xinya X; Zemmar, Ajmal A; Sumardi, Fitri F; Hernesniemi, Juha J; Kong, Lingfei L; Liu, Gang G; Li, Ming M; Wang, Meiyun M; Li, Tianxiao T; Bu, Xingyao X
Publication Date: 2021-11

Variant appearance in text: EGFR: 1793G>T; Gly598Val
PubMed Link: 34841677
Variant Present in the following documents:
  • CTM2-11-e567-s004.xlsx, sheet 5
View BVdb publication page



Current Advances and Challenges in Radiomics of Brain Tumors.

Frontiers In Oncology
Yi, Zhenjie Z; Long, Lifu L; Zeng, Yu Y; Liu, Zhixiong Z
Publication Date: 2021

Variant appearance in text: EGFR: G598V
PubMed Link: 34722274
Variant Present in the following documents:
  • Main text
  • fonc-11-732196.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: EGFR: G598V
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Characterization of the Genomic and Immunologic Diversity of Malignant Brain Tumors through Multisector Analysis.

Cancer Discovery
Schaettler, Maximilian O MO; Richters, Megan M MM; Wang, Anthony Z AZ; Skidmore, Zachary L ZL; Fisk, Bryan B; Miller, Katherine E KE; Vickery, Tammi L TL; Kim, Albert H AH; Chicoine, Michael R MR; Osbun, Joshua W JW; Leuthardt, Eric C EC; Dowling, Joshua L JL; Zipfel, Gregory J GJ; Dacey, Ralph G RG; Lu, Hsiang-Chih HC; Johanns, Tanner M TM; Griffith, Obi L OL; Mardis, Elaine R ER; Griffith, Malachi M; Dunn, Gavin P GP
Publication Date: 2022-01

Variant appearance in text: EGFR: 1793G>T; Gly598Val
PubMed Link: 34610950
Variant Present in the following documents:
  • cd-21-0291_supplementary_table_1_suppst1.xlsx, sheet 42
  • cd-21-0291_supplementary_table_1_suppst1.xlsx, sheet 40
  • cd-21-0291_supplementary_table_3_suppst3.xlsx, sheet 39
  • cd-21-0291_supplementary_table_4_suppst4.xlsx, sheet 39
  • cd-21-0291_supplementary_table_1_suppst1.xlsx, sheet 39
  • cd-21-0291_supplementary_table_1_suppst1.xlsx, sheet 41
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Gly598Val
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Gly598Val
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



High-Affinity Chimeric Antigen Receptor With Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms.

Frontiers In Oncology
Thokala, Radhika R; Binder, Zev A ZA; Yin, Yibo Y; Zhang, Logan L; Zhang, Jiasi Vicky JV; Zhang, Daniel Y DY; Milone, Michael C MC; Ming, Guo-Li GL; Song, Hongjun H; O'Rourke, Donald M DM
Publication Date: 2021

Variant appearance in text: EGFR: G598V
PubMed Link: 34568006
Variant Present in the following documents:
  • Main text
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (Cambridge (Mass.))
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: G598V
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (New York, N.Y.)
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: G598V
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
View BVdb publication page



Establishment of an Endocytosis-Related Prognostic Signature for Patients With Low-Grade Glioma.

Frontiers In Genetics
Wang, Dawei D; Liu, Shiguang S; Wang, Guangxin G
Publication Date: 2021

Variant appearance in text: EGFR: G598V
PubMed Link: 34552618
Variant Present in the following documents:
  • Main text
  • fgene-12-709666.pdf
View BVdb publication page



Fragmentation patterns and personalized sequencing of cell-free DNA in urine and plasma of glioma patients.

Embo Molecular Medicine
Mouliere, Florent F; Smith, Christopher G CG; Heider, Katrin K; Su, Jing J; van der Pol, Ymke Y; Thompson, Mareike M; Morris, James J; Wan, Jonathan C M JCM; Chandrananda, Dineika D; Hadfield, James J; Grzelak, Marta M; Hudecova, Irena I; Couturier, Dominique-Laurent DL; Cooper, Wendy W; Zhao, Hui H; Gale, Davina D; Eldridge, Matthew M; Watts, Colin C; Brindle, Kevin K; Rosenfeld, Nitzan N; Mair, Richard R
Publication Date: 2021-08-09

Variant appearance in text: EGFR: 1793G>T; Gly598Val; rs139236063
PubMed Link: 34291583
Variant Present in the following documents:
  • EMMM-13-e12881-s004.xlsx, sheet 1
View BVdb publication page



Nivolumab Plus Ipilimumab vs Nivolumab for Previously Treated Patients With Stage IV Squamous Cell Lung Cancer: The Lung-MAP S1400I Phase 3 Randomized Clinical Trial.

Jama Oncology
Gettinger, Scott N SN; Redman, Mary W MW; Bazhenova, Lyudmila L; Hirsch, Fred R FR; Mack, Philip C PC; Schwartz, Lawrence H LH; Bradley, Jeffrey D JD; Stinchcombe, Thomas E TE; Leighl, Natasha B NB; Ramalingam, Suresh S SS; Tavernier, Susan S SS; Yu, Hui H; Unger, Joseph M JM; Minichiello, Katherine K; Highleyman, Louise L; Papadimitrakopoulou, Vassiliki A VA; Kelly, Karen K; Gandara, David R DR; Herbst, Roy S RS
Publication Date: 2021-09-01

Variant appearance in text: EGFR: G598V
PubMed Link: 34264316
Variant Present in the following documents:
  • jamaoncol-e212209-s001.pdf
  • jamaoncol-e212209-s002.pdf
View BVdb publication page



Systematic Review on the Association of Radiomics with Tumor Biological Endpoints.

Cancers
La Greca Saint-Esteven, Agustina A; Vuong, Diem D; Tschanz, Fabienne F; van Timmeren, Janita E JE; Dal Bello, Riccardo R; Waller, Verena V; Pruschy, Martin M; Guckenberger, Matthias M; Tanadini-Lang, Stephanie S
Publication Date: 2021-06-16

Variant appearance in text: EGFR: G598V
PubMed Link: 34208595
Variant Present in the following documents:
  • Main text
  • cancers-13-03015.pdf
View BVdb publication page



Improvement of Neoantigen Identification Through Convolution Neural Network.

Frontiers In Immunology
Hao, Qing Q; Wei, Ping P; Shu, Yang Y; Zhang, Yi-Guan YG; Xu, Heng H; Zhao, Jun-Ning JN
Publication Date: 2021

Variant appearance in text: EGFR: G598V
PubMed Link: 34113354
Variant Present in the following documents:
  • Table_1.xlsx, sheet 15
View BVdb publication page



Genomic Profiling Identified Novel Prognostic Biomarkers in Chinese Midline Glioma Patients.

Frontiers In Oncology
Li, Hainan H; Shan, Changguo C; Wu, Shengnan S; Cheng, Baijie B; Fan, Chongzu C; Cai, Linbo L; Chen, Yedan Y; Shi, Yuqian Y; Liu, Kaihua K; Shao, Yang Y; Zhu, Dan D; Li, Zhi Z
Publication Date: 2020

Variant appearance in text: EGFR: G598V
PubMed Link: 33747896
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: EGFR: 1793G>T; G598V
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Case Report: Afatinib Treatment in a Patient With NSCLC Harboring a Rare EGFR Exon 20 Mutation.

Frontiers In Oncology
Zöchbauer-Müller, Sabine S; Kaserer, Bettina B; Prosch, Helmut H; Cseh, Agnieszka A; Solca, Flavio F; Bauer, Markus Johann MJ; Müllauer, Leonhard L
Publication Date: 2020

Variant appearance in text: EGFR: G598V
PubMed Link: 33575211
Variant Present in the following documents:
  • Main text
  • fonc-10-593852.pdf
View BVdb publication page



A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement.

Nature Communications
Zhang, Yiqun Y; Chen, Fengju F; Donehower, Lawrence A LA; Scheurer, Michael E ME; Creighton, Chad J CJ
Publication Date: 2021-02-10

Variant appearance in text: EGFR: 1793G>T; Gly598Val; rs139236063
PubMed Link: 33568653
Variant Present in the following documents:
  • 41467_2021_21081_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



Online informatics resources to facilitate cancer target and chemical probe discovery.

Rsc Medicinal Chemistry
Yang, Xuan X; Fu, Haian H; Ivanov, Andrey A AA
Publication Date: 2020-06-01

Variant appearance in text: EGFR: G598V
PubMed Link: 33479663
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeting G1/S phase cell-cycle genomic alterations and accompanying co-alterations with individualized CDK4/6 inhibitor-based regimens.

Jci Insight
Kato, Shumei S; Okamura, Ryosuke R; Adashek, Jacob J JJ; Khalid, Noor N; Lee, Suzanna S; Nguyen, Van V; Sicklick, Jason K JK; Kurzrock, Razelle R
Publication Date: 2021-01-11

Variant appearance in text: EGFR: G598V
PubMed Link: 33427211
Variant Present in the following documents:
  • jciinsight-6-142547-s159.pdf
View BVdb publication page



Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine
Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS
Publication Date: 2021-01

Variant appearance in text: EGFR: G598V
PubMed Link: 33314633
Variant Present in the following documents:
  • CAM4-10-53-s002.xlsx, sheet 1
View BVdb publication page



Correlation of genetic alterations by whole-exome sequencing with clinical outcomes of glioblastoma patients from the Lebanese population.

Plos One
Saadeh, Fadi S FS; Morsi, Rami Z RZ; El-Kurdi, Abdallah A; Nemer, Georges G; Mahfouz, Rami R; Charafeddine, Maya M; Khoury, Jessica J; Najjar, Marwan W MW; Khoueiry, Pierre P; Assi, Hazem I HI
Publication Date: 2020

Variant appearance in text: EGFR: G598V
PubMed Link: 33237934
Variant Present in the following documents:
  • Main text
  • pone.0242793.s003.xlsx, sheet 1
View BVdb publication page



Tyrosine Kinase Receptors in Oncology.

International Journal Of Molecular Sciences
Esteban-Villarrubia, Jorge J; Soto-Castillo, Juan José JJ; Pozas, Javier J; San Román-Gil, María M; Orejana-Martín, Inmaculada I; Torres-Jiménez, Javier J; Carrato, Alfredo A; Alonso-Gordoa, Teresa T; Molina-Cerrillo, Javier J
Publication Date: 2020-11-12

Variant appearance in text: EGFR: G598V
PubMed Link: 33198314
Variant Present in the following documents:
  • Main text
  • ijms-21-08529.pdf
View BVdb publication page



The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study.

Frontiers In Immunology
Punta, Marco M; Jennings, Victoria A VA; Melcher, Alan A AA; Lise, Stefano S
Publication Date: 2020

Variant appearance in text: EGFR: G598V
PubMed Link: 33133066
Variant Present in the following documents:
  • Table_6.xlsx, sheet 7
  • Table_6.xlsx, sheet 2
  • Table_1.xlsx, sheet 2
View BVdb publication page



A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR.

Neuro-Oncology
Sievers, Philipp P; Sill, Martin M; Schrimpf, Daniel D; Stichel, Damian D; Reuss, David E DE; Sturm, Dominik D; Hench, Jürgen J; Frank, Stephan S; Krskova, Lenka L; Vicha, Ales A; Zapotocky, Michal M; Bison, Brigitte B; Castel, David D; Grill, Jacques J; Debily, Marie-Anne MA; Harter, Patrick N PN; Snuderl, Matija M; Kramm, Christof M CM; Reifenberger, Guido G; Korshunov, Andrey A; Jabado, Nada N; Wesseling, Pieter P; Wick, Wolfgang W; Solomon, David A DA; Perry, Arie A; Jacques, Thomas S TS; Jones, Chris C; Witt, Olaf O; Pfister, Stefan M SM; von Deimling, Andreas A; Jones, David T W DTW; Sahm, Felix F
Publication Date: 2021-01-30

Variant appearance in text: EGFR: G598V
PubMed Link: 33130881
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeted Genomic Sequencing Reveals Different Evolutionary Patterns Between Locally and Distally Recurrent Glioblastomas.

Cancer Genomics & Proteomics
Yoon, Nara N; Kim, Hyun-Soo HS; Lee, Jung Whee JW; Lee, Eui-Jin EJ; Maeng, Lee-So LS; Yoon, Wan Soo WS
Publication Date: 2020

Variant appearance in text: EGFR: Gly598Val
PubMed Link: 33099481
Variant Present in the following documents:
  • Main text
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs139236063
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.

Acta Neuropathologica
Golebiewska, Anna A; Hau, Ann-Christin AC; Oudin, Anaïs A; Stieber, Daniel D; Yabo, Yahaya A YA; Baus, Virginie V; Barthelemy, Vanessa V; Klein, Eliane E; Bougnaud, Sébastien S; Keunen, Olivier O; Wantz, May M; Michelucci, Alessandro A; Neirinckx, Virginie V; Muller, Arnaud A; Kaoma, Tony T; Nazarov, Petr V PV; Azuaje, Francisco F; De Falco, Alfonso A; Flies, Ben B; Richart, Lorraine L; Poovathingal, Suresh S; Arns, Thais T; Grzyb, Kamil K; Mock, Andreas A; Herold-Mende, Christel C; Steino, Anne A; Brown, Dennis D; May, Patrick P; Miletic, Hrvoje H; Malta, Tathiane M TM; Noushmehr, Houtan H; Kwon, Yong-Jun YJ; Jahn, Winnie W; Klink, Barbara B; Tanner, Georgette G; Stead, Lucy F LF; Mittelbronn, Michel M; Skupin, Alexander A; Hertel, Frank F; Bjerkvig, Rolf R; Niclou, Simone P SP
Publication Date: 2020-12

Variant appearance in text: EGFR: G598V
PubMed Link: 33009951
Variant Present in the following documents:
  • Main text
  • 401_2020_2226_MOESM1_ESM.pdf
  • 401_2020_Article_2226.pdf
View BVdb publication page