EGFR c.1924A>G ;(p.K642E)

Variant ID: 7-55240680-A-G

NM_005228.3(EGFR):c.1924A>G;(p.K642E)

This variant was identified in 16 publications

View GRCh38 version.




Publications:


Genomics-Driven Precision Medicine in Pediatric Solid Tumors.

Cancers
Suthapot, Praewa P; Chiangjong, Wararat W; Chaiyawat, Parunya P; Choochuen, Pongsakorn P; Pruksakorn, Dumnoensun D; Sangkhathat, Surasak S; Hongeng, Suradej S; Anurathapan, Usanarat U; Chutipongtanate, Somchai S
Publication Date: 2023-02-23

Variant appearance in text: EGFR: K642E
PubMed Link: 36900212
Variant Present in the following documents:
  • cancers-15-01418.pdf
View BVdb publication page



Liquid Profiling for Cancer Patient Stratification in Precision Medicine-Current Status and Challenges for Successful Implementation in Standard Care.

Diagnostics (Basel, Switzerland)
Haselmann, Verena V; Hedtke, Maren M; Neumaier, Michael M
Publication Date: 2022-03-19

Variant appearance in text: EGFR: K642E
PubMed Link: 35328301
Variant Present in the following documents:
  • diagnostics-12-00748.pdf
View BVdb publication page



Deep analysis of neuroblastoma core regulatory circuitries using online databases and integrated bioinformatics shows their pan-cancer roles as prognostic predictors.

Discover. Oncology
Jahangiri, Leila L; Pucci, Perla P; Ishola, Tala T; Pereira, Joao J; Cavanagh, Megan L ML; Turner, Suzanne D SD
Publication Date: 2021-11-29

Variant appearance in text: EGFR: K642E
PubMed Link: 35201514
Variant Present in the following documents:
  • 12672_2021_452_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Evolution of kinase polypharmacology across HSP90 drug discovery.

Cell Chemical Biology
Antolin, Albert A AA; Clarke, Paul A PA; Collins, Ian I; Workman, Paul P; Al-Lazikani, Bissan B
Publication Date: 2021-10-21

Variant appearance in text: EGFR: K642E
PubMed Link: 34077750
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
View BVdb publication page



Druggable targets meet oncogenic drivers: opportunities and limitations of target-based classification of tumors and the role of Molecular Tumor Boards.

Esmo Open
Danesi, R R; Fogli, S S; Indraccolo, S S; Del Re, M M; Dei Tos, A P AP; Leoncini, L L; Antonuzzo, L L; Bonanno, L L; Guarneri, V V; Pierini, A A; Amunni, G G; Conte, P P
Publication Date: 2021-04

Variant appearance in text: EGFR: K642E
PubMed Link: 33540286
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Molecular Diagnostic of Solid Tumor Using a Next Generation Sequencing Custom-Designed Multi-Gene Panel.

Diagnostics (Basel, Switzerland)
de Biase, Dario D; Acquaviva, Giorgia G; Visani, Michela M; Sanza, Viviana V; Argento, Chiara M CM; De Leo, Antonio A; Maloberti, Thais T; Pession, Annalisa A; Tallini, Giovanni G
Publication Date: 2020-04-23

Variant appearance in text: EGFR: 1924A>G; K642E
PubMed Link: 32340363
Variant Present in the following documents:
  • diagnostics-10-00250-s001.pdf
View BVdb publication page



Computational algorithms for in silico profiling of activating mutations in cancer.

Cellular And Molecular Life Sciences : Cmls
Jordan, E Joseph EJ; Patil, Keshav K; Suresh, Krishna K; Park, Jin H JH; Mosse, Yael P YP; Lemmon, Mark A MA; Radhakrishnan, Ravi R
Publication Date: 2019-07

Variant appearance in text: EGFR: K642E
PubMed Link: 30982079
Variant Present in the following documents:
  • Main text
View BVdb publication page



Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports
Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS
Publication Date: 2018-04-03

Variant appearance in text: EGFR: Lys642Glu
PubMed Link: 29617658
Variant Present in the following documents:
  • NIHMS958974-supplement-6.xlsx, sheet 1
View BVdb publication page



The AURORA pilot study for molecular screening of patients with advanced breast cancer-a study of the breast international group.

Npj Breast Cancer
Maetens, Marion M; Brown, David D; Irrthum, Alexandre A; Aftimos, Philippe P; Viale, Giuseppe G; Loibl, Sibylle S; Laes, Jean-François JF; Campbell, Peter J PJ; Thompson, Alastair A; Cortes, Javier J; Seiler, Sabine S; Vinnicombe, Sara S; Oliveira, Mafalda M; Rothé, Françoise F; Bareche, Yacine Y; Fumagalli, Debora D; Zardavas, Dimitrios D; Desmedt, Christine C; Piccart, Martine M; Loi, Sherene S; Sotiriou, Christos C
Publication Date: 2017

Variant appearance in text: EGFR: K642E
PubMed Link: 28685159
Variant Present in the following documents:
  • 41523_2017_26_MOESM12_ESM.xlsx, sheet 1
View BVdb publication page



Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer.

Oncotarget
Xu, Naiqing N; Fang, Wenfeng W; Mu, Libing L; Tang, Yanna Y; Gao, Lei L; Ren, Shengxiang S; Cao, Dengfeng D; Zhou, Lixin L; Zhang, Aiqun A; Liu, Deruo D; Zhou, Caicun C; Wong, Kwok-Kin KK; Yu, Lei L; Zhang, Li L; Chen, Liang L
Publication Date: 2016-01-26

Variant appearance in text: EGFR: K642E
PubMed Link: 26646697
Variant Present in the following documents:
  • oncotarget-07-3884-s001.pdf
View BVdb publication page



Novel receptor tyrosine kinase targeted combination therapies for imatinib-resistant gastrointestinal stromal tumors (GIST).

Oncotarget
Mahadevan, Daruka D; Theiss, Noah N; Morales, Carla C; Stejskal, Amy E AE; Cooke, Laurence S LS; Zhu, Min M; Kurtzman, Drew D; Swart, Rachel R; Ong, Evan E; Qi, Wenqing W
Publication Date: 2015-02-10

Variant appearance in text: EGFR: K642E
PubMed Link: 25557174
Variant Present in the following documents:
  • Main text
  • oncotarget-06-1954.pdf
View BVdb publication page



Oncogene mutational profile in nasopharyngeal carcinoma.

Oncotargets And Therapy
Zhang, Zi-Chen ZC; Fu, Sha S; Wang, Fang F; Wang, Hai-Yun HY; Zeng, Yi-Xin YX; Shao, Jian-Yong JY
Publication Date: 2014

Variant appearance in text: EGFR: K642E
PubMed Link: 24672248
Variant Present in the following documents:
  • ott-7-457.pdf
View BVdb publication page



ERBB4 mutation analysis: emerging molecular target for melanoma treatment.

Methods In Molecular Biology (Clifton, N.J.)
Lau, Christopher C; Killian, Keith J KJ; Samuels, Yardena Y; Rudloff, Udo U
Publication Date: 2014

Variant appearance in text: ERBB: K642E
PubMed Link: 24258993
Variant Present in the following documents:
  • Main text
View BVdb publication page



Using noun phrases for navigating biomedical literature on Pubmed: how many updates are we losing track of?

Plos One
Srikrishna, Devabhaktuni D; Coram, Marc A MA
Publication Date: 2011

Variant appearance in text: EGFR: K642E
PubMed Link: 21935487
Variant Present in the following documents:
  • pone.0024920.s002.pdf
View BVdb publication page



A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.

Bmc Cancer
Fumagalli, Debora D; Gavin, Patrick G PG; Taniyama, Yusuke Y; Kim, Seung-Il SI; Choi, Hyun-Joo HJ; Paik, Soonmyung S; Pogue-Geile, Katherine L KL
Publication Date: 2010-03-16

Variant appearance in text: EGFR: K642E
PubMed Link: 20233444
Variant Present in the following documents:
  • Main text
  • 1471-2407-10-101.pdf
View BVdb publication page



Role for the proapoptotic factor BIM in mediating imatinib-induced apoptosis in a c-KIT-dependent gastrointestinal stromal tumor cell line.

The Journal Of Biological Chemistry
Gordon, Peter M PM; Fisher, David E DE
Publication Date: 2010-05-07

Variant appearance in text: EGFR: K642E
PubMed Link: 20231287
Variant Present in the following documents:
  • Main text
View BVdb publication page