EGFR c.2008A>T ;(p.R670W)

Variant ID: 7-55240764-A-T

NM_005228.3(EGFR):c.2008A>T;(p.R670W)

This variant was identified in 13 publications

View GRCh38 version.




Publications:


EGFR p.V774M/p.L833V compound mutations in lung adenocarcinoma responded well to almonertinib: a case report.

Frontiers In Oncology
Pan, Hai H; Zhang, Linlin L; Meng, Fanlu F; Guan, Shasha S; Zhong, Diansheng D
Publication Date: 2023

Variant appearance in text: EGFR: R670W
PubMed Link: 37251951
Variant Present in the following documents:
  • Main text
  • fonc-13-1159308.pdf
View BVdb publication page



A L833V/H835L EGFR variant lung adenocarcinoma with skin metastasis: A case report and literature review.

Heliyon
Yang, Xian X; Yao, Yang Y; Zhu, Qing Q
Publication Date: 2022-12

Variant appearance in text: EGFR: R670W
PubMed Link: 36531621
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Inconsistent clinical outcomes following afatinib treatment in NSCLC patients harboring uncommon epidermal growth factor receptor mutation.

Frontiers In Oncology
Dong, Wei W; Wang, Congjie C; Wang, Chunsheng C; Zhao, Kewei K; Ma, Zhao Z; Hu, Shanliang S
Publication Date: 2022

Variant appearance in text: EGFR: R670W
PubMed Link: 36425553
Variant Present in the following documents:
  • DataSheet_1.pdf
View BVdb publication page



Effective treatment with icotinib in advanced lung adenocarcinoma harboring rare EGFR mutation G719A/L833V: A case report.

Medicine
Zhou, Bin B; Wang, Yanan Y; Liao, Haijiang H; Li, Ben B
Publication Date: 2022-08-19

Variant appearance in text: EGFR: R670W
PubMed Link: 35984165
Variant Present in the following documents:
  • medi-101-e30080.pdf
View BVdb publication page



Tyrosine Kinase Inhibitor Activity in Patients with NSCLC Harboring Uncommon EGFR Mutations: A Retrospective International Cohort Study (UpSwinG).

The Oncologist
Popat, Sanjay S; Hsia, Te-Chun TC; Hung, Jen-Yu JY; Jung, Hyun Ae HA; Shih, Jin-Yuan JY; Park, Cheol Kyu CK; Lee, Seung Hyeun SH; Okamoto, Tatsuro T; Ahn, Hee Kyung HK; Lee, Yong Chul YC; Sato, Yuki Y; Lee, Sung Sook SS; Mascaux, Celine C; Daoud, Hasan H; Märten, Angela A; Miura, Satoru S
Publication Date: 2022-04-05

Variant appearance in text: EGFR: R670W
PubMed Link: 35274704
Variant Present in the following documents:
  • oyac022.pdf
View BVdb publication page



Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer
Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J
Publication Date: 2021-11

Variant appearance in text: EGFR: R670W
PubMed Link: 34549528
Variant Present in the following documents:
  • TCA-12-2924.pdf
View BVdb publication page



Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer
Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J
Publication Date: 2021-11

Variant appearance in text: EGFR: R670W
PubMed Link: 34549528
Variant Present in the following documents:
  • TCA-12-2924.pdf
View BVdb publication page



Successful treatment of triple EGFR mutation T785A/L861Q/H297_E298 with afatinib.

Thoracic Cancer
Longo, Vito V; Catino, Annamaria A; Montrone, Michele M; Pizzutilo, Pamela P; Pesola, Francesco F; Marech, Ilaria I; Capone, Iolanda I; Prelaj, Arsela A; Galetta, Domenico D
Publication Date: 2021-07

Variant appearance in text: EGFR: R670W
PubMed Link: 34008923
Variant Present in the following documents:
  • Main text
  • TCA-12-2031.pdf
View BVdb publication page



Great Efficacy of Afatinib in a Patient with Lung Adenocarcinoma Harboring EGFR L833V/H835L Mutations: A Case Report.

Oncotargets And Therapy
Long, Xiang X; Qin, Tian T; Lin, Junhong J
Publication Date: 2020

Variant appearance in text: EGFR: R670W
PubMed Link: 33116645
Variant Present in the following documents:
  • Main text
  • ott-13-10689.pdf
View BVdb publication page



Current Approaches in NSCLC Targeting K-RAS and EGFR.

International Journal Of Molecular Sciences
Aran, Veronica V; Omerovic, Jasminka J
Publication Date: 2019-11-14

Variant appearance in text: EGFR: R670W
PubMed Link: 31739412
Variant Present in the following documents:
  • Main text
  • ijms-20-05701.pdf
View BVdb publication page



The Value of Liquid Biopsies for Guiding Therapy Decisions in Non-small Cell Lung Cancer.

Frontiers In Oncology
Saarenheimo, Jatta J; Eigeliene, Natalja N; Andersen, Heidi H; Tiirola, Marja M; Jekunen, Antti A
Publication Date: 2019

Variant appearance in text: EGFR: R670W
PubMed Link: 30891428
Variant Present in the following documents:
  • Main text
  • fonc-09-00129.pdf
View BVdb publication page



The effectiveness of afatinib and osimertinib in a Chinese patient with advanced lung adenocarcinoma harboring a rare triple EGFR mutation (R670W/H835L/L833V): a case report and literature review.

Oncotargets And Therapy
Qin, Bao-Dong BD; Jiao, Xiao-Dong XD; Yuan, Ling-Yan LY; Liu, Ke K; Wang, Zhan Z; Qin, Wen-Xing WX; Zang, Yuan-Sheng YS
Publication Date: 2018

Variant appearance in text: EGFR: R670W
PubMed Link: 30127622
Variant Present in the following documents:
  • Main text
  • ott-11-4739.pdf
View BVdb publication page



Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.

Cell
Creixell, Pau P; Schoof, Erwin M EM; Simpson, Craig D CD; Longden, James J; Miller, Chad J CJ; Lou, Hua Jane HJ; Perryman, Lara L; Cox, Thomas R TR; Zivanovic, Nevena N; Palmeri, Antonio A; Wesolowska-Andersen, Agata A; Helmer-Citterich, Manuela M; Ferkinghoff-Borg, Jesper J; Itamochi, Hiroaki H; Bodenmiller, Bernd B; Erler, Janine T JT; Turk, Benjamin E BE; Linding, Rune R
Publication Date: 2015-09-24

Variant appearance in text: EGFR: R670W
PubMed Link: 26388441
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
View BVdb publication page



The sequence-specific transcription factor c-Jun targets Cockayne syndrome protein B to regulate transcription and chromatin structure.

Plos Genetics
Lake, Robert J RJ; Boetefuer, Erica L EL; Tsai, Pei-Fang PF; Jeong, Jieun J; Choi, Inchan I; Won, Kyoung-Jae KJ; Fan, Hua-Ying HY
Publication Date: 2014-04

Variant appearance in text: EGFR: R670W
PubMed Link: 24743307
Variant Present in the following documents:
  • Main text
View BVdb publication page