EGFR c.2062C>T ;(p.L688F)

Variant ID: 7-55241614-C-T

NM_005228.3(EGFR):c.2062C>T;(p.L688F)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics
G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A
Publication Date: 2022

Variant appearance in text: EGFR: L688F
PubMed Link: 36561320
Variant Present in the following documents:
  • Table3.xlsx, sheet 1
  • Table2.xlsx, sheet 4
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2062C>T
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Small-Molecule Inhibitors (SMIs) as an Effective Therapeutic Strategy for Endometrial Cancer.

Cancers
Megino-Luque, Cristina C; Moiola, Cristian Pablo CP; Molins-Escuder, Clara C; López-Gil, Carlos C; Gil-Moreno, Antonio A; Matias-Guiu, Xavier X; Colas, Eva E; Eritja, Núria N
Publication Date: 2020-09-24

Variant appearance in text: EGFR: L688F
PubMed Link: 32987790
Variant Present in the following documents:
  • Main text
  • cancers-12-02751.pdf
View BVdb publication page



Multigene Mutation Profiling and Clinical Characteristics of Small-Cell Lung Cancer in Never-Smokers vs. Heavy Smokers (Geno1.3-CLICaP).

Frontiers In Oncology
Cardona, Andrés F AF; Rojas, Leonardo L; Zatarain-Barrón, Zyanya Lucia ZL; Ruiz-Patiño, Alejandro A; Ricaurte, Luisa L; Corrales, Luis L; Martín, Claudio C; Freitas, Helano H; Cordeiro de Lima, Vladmir Cláudio VC; Rodriguez, July J; Avila, Jenny J; Bravo, Melissa M; Archila, Pilar P; Carranza, Hernán H; Vargas, Carlos C; Otero, Jorge J; Barrón, Feliciano F; Karachaliou, Niki N; Rosell, Rafael R; Arrieta, Oscar O
Publication Date: 2019

Variant appearance in text: EGFR: L688F
PubMed Link: 31058075
Variant Present in the following documents:
  • Main text
  • fonc-09-00254.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: L688F
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Cancer Biology & Therapy
Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS
Publication Date: 2016

Variant appearance in text: EGFR: L688F
PubMed Link: 26785607
Variant Present in the following documents:
  • Main text
  • kcbt-17-03-1139235.pdf
View BVdb publication page



Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma.

Bmc Cancer
Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Kim, Arum A; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS
Publication Date: 2016-01-18

Variant appearance in text: EGFR: 2062C>T
PubMed Link: 26782967
Variant Present in the following documents:
  • 12885_2016_2049_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.

Cell
Creixell, Pau P; Schoof, Erwin M EM; Simpson, Craig D CD; Longden, James J; Miller, Chad J CJ; Lou, Hua Jane HJ; Perryman, Lara L; Cox, Thomas R TR; Zivanovic, Nevena N; Palmeri, Antonio A; Wesolowska-Andersen, Agata A; Helmer-Citterich, Manuela M; Ferkinghoff-Borg, Jesper J; Itamochi, Hiroaki H; Bodenmiller, Bernd B; Erler, Janine T JT; Turk, Benjamin E BE; Linding, Rune R
Publication Date: 2015-09-24

Variant appearance in text: EGFR: L688F
PubMed Link: 26388441
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
View BVdb publication page



Lapatinib and potential prognostic value of EGFR mutations in a Gynecologic Oncology Group phase II trial of persistent or recurrent endometrial cancer.

Gynecologic Oncology
Leslie, Kimberly K KK; Sill, Michael W MW; Lankes, Heather A HA; Fischer, Edgar G EG; Godwin, Andrew K AK; Gray, Heidi H; Schilder, Russell J RJ; Walker, Joan L JL; Tewari, Krishnansu K; Hanjani, Parviz P; Abulafia, Ovadia O; Rose, Peter G PG
Publication Date: 2012-11

Variant appearance in text: EGFR: L688F
PubMed Link: 22885469
Variant Present in the following documents:
  • Main text
View BVdb publication page