EGFR c.2068G>A ;(p.E690K)

Variant ID: 7-55241620-G-A

NM_005228.3(EGFR):c.2068G>A;(p.E690K)

This variant was identified in 13 publications

View GRCh38 version.




Publications:


Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: EGFR: 2068G>A; Glu690Lys
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics
G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A
Publication Date: 2022

Variant appearance in text: EGFR: E690K
PubMed Link: 36561320
Variant Present in the following documents:
  • Table3.xlsx, sheet 1
  • Table2.xlsx, sheet 4
View BVdb publication page



Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research
Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL
Publication Date: 2022-05

Variant appearance in text: EGFR: E690K
PubMed Link: 35229492
Variant Present in the following documents:
  • PCMR-35-369-s003.xlsx, sheet 12
View BVdb publication page



The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer
Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J
Publication Date: 2022-02

Variant appearance in text: EGFR: Glu690Lys
PubMed Link: 35221333
Variant Present in the following documents:
  • 43018_2022_332_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Small-Molecule Inhibitors (SMIs) as an Effective Therapeutic Strategy for Endometrial Cancer.

Cancers
Megino-Luque, Cristina C; Moiola, Cristian Pablo CP; Molins-Escuder, Clara C; López-Gil, Carlos C; Gil-Moreno, Antonio A; Matias-Guiu, Xavier X; Colas, Eva E; Eritja, Núria N
Publication Date: 2020-09-24

Variant appearance in text: EGFR: E690K
PubMed Link: 32987790
Variant Present in the following documents:
  • Main text
  • cancers-12-02751.pdf
View BVdb publication page



Pathogenesis and Clinical Management of Uterine Serous Carcinoma.

Cancers
Zhang, Li L; Kwan, Suet Ying SY; Wong, Kwong Kwok KK; Solaman, Pamela T PT; Lu, Karen H KH; Mok, Samuel C SC
Publication Date: 2020-03-14

Variant appearance in text: EGFR: E690K
PubMed Link: 32183290
Variant Present in the following documents:
  • Main text
  • cancers-12-00686.pdf
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: EGFR: E690K
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



Integrative omics analyses broaden treatment targets in human cancer.

Genome Medicine
Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L
Publication Date: 2018-07-27

Variant appearance in text: EGFR: E690K
PubMed Link: 30053901
Variant Present in the following documents:
  • 13073_2018_564_MOESM2_ESM.xlsx, sheet 3
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: ERBB: 2068G>A
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: EGFR: E690K
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page



Molecular staging of gynecological cancer: What is the future?

Best Practice & Research. Clinical Obstetrics & Gynaecology
Binder, Pratibha S PS; Prat, Jaime J; Mutch, David G DG
Publication Date: 2015-08

Variant appearance in text: EGFR: E690K
PubMed Link: 25934522
Variant Present in the following documents:
  • Main text
View BVdb publication page



Comprehensive profiling of EGFR/HER receptors for personalized treatment of gynecologic cancers.

Molecular Diagnosis & Therapy
Reyes, Henry D HD; Thiel, Kristina W KW; Carlson, Matthew J MJ; Meng, Xiangbing X; Yang, Shujie S; Stephan, Jean-Marie JM; Leslie, Kimberly K KK
Publication Date: 2014-04

Variant appearance in text: EGFR: E690K
PubMed Link: 24403167
Variant Present in the following documents:
  • Main text
View BVdb publication page



Lapatinib and potential prognostic value of EGFR mutations in a Gynecologic Oncology Group phase II trial of persistent or recurrent endometrial cancer.

Gynecologic Oncology
Leslie, Kimberly K KK; Sill, Michael W MW; Lankes, Heather A HA; Fischer, Edgar G EG; Godwin, Andrew K AK; Gray, Heidi H; Schilder, Russell J RJ; Walker, Joan L JL; Tewari, Krishnansu K; Hanjani, Parviz P; Abulafia, Ovadia O; Rose, Peter G PG
Publication Date: 2012-11

Variant appearance in text: EGFR: E690K
PubMed Link: 22885469
Variant Present in the following documents:
  • Main text
View BVdb publication page