EGFR c.2127A>C ;(p.E709D)

Variant ID: 7-55241679-A-C

NM_005228.3(EGFR):c.2127A>C;(p.E709D)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.

Cancers
Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC
Publication Date: 2021-07-20

Variant appearance in text: EGFR: E709D
PubMed Link: 34298851
Variant Present in the following documents:
  • Main text
  • cancers-13-03641.pdf
View BVdb publication page



Discrepancies between ALK protein disruption and occurrence of ALK gene rearrangement in Polish NSCLC patients.

Journal Of Thoracic Disease
Grenda, Anna A; Jarosz, Bożena B; Krawczyk, Paweł P; Kucharczyk, Tomasz T; Wojas-Krawczyk, Kamila K; Reszka, Katarzyna K; Krukowska, Kinga K; Nicoś, Marcin M; Pankowski, Juliusz J; Bryl, Maciej M; Ramlau, Rodryg R; Kuźnar-Kamińska, Barbara B; Grodzki, Tomasz T; Szczęsna, Aleksandra A; Siemiątkowska, Krystyna K; Szumiło, Justyna J; Batura-Gabryel, Halina H; Palonka, Michał M; Milanowski, Janusz J
Publication Date: 2018-08

Variant appearance in text: EGFR: 2127A>C; Glu709Asp
PubMed Link: 30233874
Variant Present in the following documents:
  • Main text
View BVdb publication page



Immunohistochemical assays incorporating SP142 and 22C3 monoclonal antibodies for detection of PD-L1 expression in NSCLC patients with known status of EGFR and ALK genes.

Oncotarget
Krawczyk, Paweł P; Jarosz, Bożena B; Kucharczyk, Tomasz T; Grenda, Anna A; Reszka, Katarzyna K; Pankowski, Juliusz J; Wojas-Krawczyk, Kamila K; Nicoś, Marcin M; Szumiło, Justyna J; Trojanowski, Tomasz T; Milanowski, Janusz J
Publication Date: 2017-09-08

Variant appearance in text: EGFR: 2127A>C; Glu709Asp
PubMed Link: 28969070
Variant Present in the following documents:
  • Main text
  • oncotarget-08-64283.pdf
View BVdb publication page



Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples.

Plos One
Betge, Johannes J; Kerr, Grainne G; Miersch, Thilo T; Leible, Svenja S; Erdmann, Gerrit G; Galata, Christian L CL; Zhan, Tianzuo T; Gaiser, Timo T; Post, Stefan S; Ebert, Matthias P MP; Horisberger, Karoline K; Boutros, Michael M
Publication Date: 2015

Variant appearance in text: EGFR: E709D
PubMed Link: 26010451
Variant Present in the following documents:
  • pone.0127146.s014.xlsx, sheet 3
View BVdb publication page



Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Lindeman, Neal I NI; Cagle, Philip T PT; Beasley, Mary Beth MB; Chitale, Dhananjay Arun DA; Dacic, Sanja S; Giaccone, Giuseppe G; Jenkins, Robert Brian RB; Kwiatkowski, David J DJ; Saldivar, Juan-Sebastian JS; Squire, Jeremy J; Thunnissen, Erik E; Ladanyi, Marc M
Publication Date: 2013-07

Variant appearance in text: EGFR: 2127A>C; E709D
PubMed Link: 23552377
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology.

Archives Of Pathology & Laboratory Medicine
Lindeman, Neal I NI; Cagle, Philip T PT; Beasley, Mary Beth MB; Chitale, Dhananjay Arun DA; Dacic, Sanja S; Giaccone, Giuseppe G; Jenkins, Robert Brian RB; Kwiatkowski, David J DJ; Saldivar, Juan-Sebastian JS; Squire, Jeremy J; Thunnissen, Erik E; Ladanyi, Marc M
Publication Date: 2013-06

Variant appearance in text: EGFR: 2127A>C; E709D
PubMed Link: 23551194
Variant Present in the following documents:
  • Main text
View BVdb publication page



Ethnic differences and functional analysis of MET mutations in lung cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Krishnaswamy, Soundararajan S; Kanteti, Rajani R; Duke-Cohan, Jonathan S JS; Loganathan, Sivakumar S; Liu, Wanqing W; Ma, Patrick C PC; Sattler, Martin M; Singleton, Patrick A PA; Ramnath, Nithya N; Innocenti, Federico F; Nicolae, Dan L DL; Ouyang, Zheng Z; Liang, Jie J; Minna, John J; Kozloff, Mark F MF; Ferguson, Mark K MK; Natarajan, Viswanathan V; Wang, Yi-Ching YC; Garcia, Joe G N JG; Vokes, Everett E EE; Salgia, Ravi R
Publication Date: 2009-09-15

Variant appearance in text: N/A
PubMed Link: 19723643
Variant Present in the following documents:
View BVdb publication page