EGFR c.2152_2153delinsGC ;(p.L718A)

Variant ID: 7-55241704-CT-GC

NM_005228.3(EGFR):c.2152_2153delinsGC;(p.L718A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Discovery of Anilino-1,4-naphthoquinones as Potent EGFR Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Comprehensive Molecular Modeling.

Acs Omega
Mahalapbutr, Panupong P; Leechaisit, Ronnakorn R; Thongnum, Anusit A; Todsaporn, Duangjai D; Prachayasittikul, Veda V; Rungrotmongkol, Thanyada T; Prachayasittikul, Supaluk S; Ruchirawat, Somsak S; Prachayasittikul, Virapong V; Pingaew, Ratchanok R
Publication Date: 2022-05-31

Variant appearance in text: EGFR: L718A
PubMed Link: 35664590
Variant Present in the following documents:
  • Main text
  • ao2c01188.pdf
View BVdb publication page



Mechanisms of resistance to irreversible epidermal growth factor receptor tyrosine kinase inhibitors and therapeutic strategies in non-small cell lung cancer.

Oncotarget
Xu, Jing J; Wang, Jinghui J; Zhang, Shucai S
Publication Date: 2017-10-27

Variant appearance in text: EGFR: L718A
PubMed Link: 29163853
Variant Present in the following documents:
  • Main text
  • oncotarget-08-90557.pdf
View BVdb publication page



Structural investigations of T854A mutation in EGFR and identification of novel inhibitors using structure activity relationships.

Bmc Genomics
Goyal, Sukriti S; Jamal, Salma S; Shanker, Asheesh A; Grover, Abhinav A
Publication Date: 2015

Variant appearance in text: EGFR: L718A
PubMed Link: 26041145
Variant Present in the following documents:
  • Main text
  • 1471-2164-16-S5-S8.pdf
View BVdb publication page