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EGFR c.2152_2153delinsGC ;(p.L718A)
Variant ID: 7-55241704-CT-GC
NM_005228.3(
EGFR
):c.2152_2153delinsGC;(p.L718A)
This variant was identified in 3 publications
View GRCh38 version.
Variant-Specific Resource Links:
gnomAD v2.1.1
Mutalizer Name Checker
Google
UCSC Genome Browser
ClinVar
dbSNP
Publications:
Discovery of Anilino-1,4-naphthoquinones as Potent EGFR Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Comprehensive Molecular Modeling.
Acs Omega
Mahalapbutr, Panupong P; Leechaisit, Ronnakorn R; Thongnum, Anusit A; Todsaporn, Duangjai D; Prachayasittikul, Veda V; Rungrotmongkol, Thanyada T; Prachayasittikul, Supaluk S; Ruchirawat, Somsak S; Prachayasittikul, Virapong V; Pingaew, Ratchanok R
Publication Date: 2022-05-31
Variant appearance in text: EGFR: L718A
PubMed Link:
35664590
Variant Present in the following documents:
Main text
ao2c01188.pdf
View BVdb publication page
Mechanisms of resistance to irreversible epidermal growth factor receptor tyrosine kinase inhibitors and therapeutic strategies in non-small cell lung cancer.
Oncotarget
Xu, Jing J; Wang, Jinghui J; Zhang, Shucai S
Publication Date: 2017-10-27
Variant appearance in text: EGFR: L718A
PubMed Link:
29163853
Variant Present in the following documents:
Main text
oncotarget-08-90557.pdf
View BVdb publication page
Structural investigations of T854A mutation in EGFR and identification of novel inhibitors using structure activity relationships.
Bmc Genomics
Goyal, Sukriti S; Jamal, Salma S; Shanker, Asheesh A; Grover, Abhinav A
Publication Date: 2015
Variant appearance in text: EGFR: L718A
PubMed Link:
26041145
Variant Present in the following documents:
Main text
1471-2164-16-S5-S8.pdf
View BVdb publication page