Publications:

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Rationale and design of a phase II trial of dacomitinib in advanced non-small cell lung cancer patients with uncommon epidermal growth factor receptor mutations: a prospective and single arm study (DANCE study).

Bmc Cancer

Zhang, Bo B; Shi, Chunlei C; Gao, Zhiqiang Z; Zhong, Hua H; Xiong, Liwen L; Gu, Aiqin A; Wang, Weimin W; Chu, Tianqing T; Zhang, Wei W; Wang, Huimin H; Zhang, Xueyan X; Zhong, Runbo R; Han, Baohui B

Publication Date: 2022-03-19

Variant appearance in text: EGFR: L718P

PubMed Link: 35305596

Variant Present in the following documents:

• Main text
• 12885_2022_Article_9409.pdf

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Durable response to afatinib in an advanced lung adenocarcinoma patient with an EGFR L858R/G729A compound mutation: a case report.

Annals Of Translational Medicine

Wu, Lige L; Fang, Cheng C; Zhao, Weiqing W; Li, Dong D; Tang, Shuxian S; Li, Xi X; Ji, Mei M

Publication Date: 2022-01

Variant appearance in text: EGFR: L718P

PubMed Link: 35282062

Variant Present in the following documents:

• Main text
• atm-10-02-116.pdf

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[A Review of EGFR-TKIs Therapy of Non-small Cell Lung Cancer
with Uncommon EGFR Mutations].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Du, Wenxing W; Wo, Yang Y; Lu, Tong T; Wang, Yuanyong Y; Jiao, Wenjie W

Publication Date: 2019-09-20

Variant appearance in text: EGFR: L718P

PubMed Link: 31526464

Variant Present in the following documents:

• Main text
• zgfazz-22-9-590.pdf

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: EGFR: L718P

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

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Heterogeneous Responses to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs) in Patients with Uncommon EGFR Mutations: New Insights and Future Perspectives in this Complex Clinical Scenario.

International Journal Of Molecular Sciences

Russo, Alessandro A; Franchina, Tindara T; Ricciardi, Giuseppina G; Battaglia, Alessandra A; Picciotto, Maria M; Adamo, Vincenzo V

Publication Date: 2019-03-21

Variant appearance in text: EGFR: L718P

PubMed Link: 30901844

Variant Present in the following documents:

• Main text
• ijms-20-01431.pdf

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[Advances in Double Mutations of EGFR and ALK Gene in Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Wang, Xin X; Zhong, Diansheng D

Publication Date: 2018-09-20

Variant appearance in text: EGFR: L718P

PubMed Link: 30201068

Variant Present in the following documents:

• Main text
• zgfazz-21-9-686.pdf

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: EGFR: L718P

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 1
• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 2

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Concomitant EML4-ALK rearrangement and EGFR mutation in non-small cell lung cancer patients: a literature review of 100 cases.

Oncotarget

Lo Russo, Giuseppe G; Imbimbo, Martina M; Corrao, Giulia G; Proto, Claudia C; Signorelli, Diego D; Vitali, Milena M; Ganzinelli, Monica M; Botta, Laura L; Zilembo, Nicoletta N; de Braud, Filippo F; Garassino, Marina Chiara MC

Publication Date: 2017-08-29

Variant appearance in text: EGFR: L718P

PubMed Link: 28938691

Variant Present in the following documents:

• Main text

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Structural basis of mutant-selectivity and drug-resistance related to CO-1686.

Oncotarget

Yan, Xiao-E XE; Zhu, Su-Jie SJ; Liang, Ling L; Zhao, Peng P; Choi, Hwan Geun HG; Yun, Cai-Hong CH

Publication Date: 2017-08-08

Variant appearance in text: EGFR: L718P

PubMed Link: 28881827

Variant Present in the following documents:

• Main text
• oncotarget-08-53508.pdf

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Responses to crizotinib and chemotherapy in patients with lung adenocarcinoma harboring a concomitant EGFR mutation and ALK gene rearrangement: A case report and review of the literature.

Molecular And Clinical Oncology

Li, Yuping Y; Su, Shanshan S; Cai, Guoping G; Lin, Quan Q; Zhou, Ying Y; Ouyang, Jinsheng J; Chen, Bicheng B; Ye, Junru J; Wu, Xiuling X; Chen, Chengshui C

Publication Date: 2017-08

Variant appearance in text: EGFR: L718P

PubMed Link: 28781781

Variant Present in the following documents:

• Main text
• mco-07-02-0173.pdf

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Concurrent EGFR Mutation and ALK Translocation in Non-Small Cell Lung Cancer.

Cureus

Sweis, Randy F RF; Thomas, Sachdev S; Bank, Bruce B; Fishkin, Paul P; Mooney, Colin C; Salgia, Ravi R

Publication Date: 2016-02-26

Variant appearance in text: EGFR: L718P

PubMed Link: 27026837

Variant Present in the following documents:

• Main text
• cureus-0008-000000000513.pdf

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Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.

Cell

Creixell, Pau P; Schoof, Erwin M EM; Simpson, Craig D CD; Longden, James J; Miller, Chad J CJ; Lou, Hua Jane HJ; Perryman, Lara L; Cox, Thomas R TR; Zivanovic, Nevena N; Palmeri, Antonio A; Wesolowska-Andersen, Agata A; Helmer-Citterich, Manuela M; Ferkinghoff-Borg, Jesper J; Itamochi, Hiroaki H; Bodenmiller, Bernd B; Erler, Janine T JT; Turk, Benjamin E BE; Linding, Rune R

Publication Date: 2015-09-24

Variant appearance in text: EGFR: L718P

PubMed Link: 26388441

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

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EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Ercan, Dalia D; Choi, Hwan Geun HG; Yun, Cai-Hong CH; Capelletti, Marzia M; Xie, Ting T; Eck, Michael J MJ; Gray, Nathanael S NS; Jänne, Pasi A PA

Publication Date: 2015-09-01

Variant appearance in text: EGFR: L718P

PubMed Link: 25948633

Variant Present in the following documents:

• Main text

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Structure-functional prediction and analysis of cancer mutation effects in protein kinases.

Computational And Mathematical Methods In Medicine

Dixit, Anshuman A; Verkhivker, Gennady M GM

Publication Date: 2014

Variant appearance in text: EGFR: L718P

PubMed Link: 24817905

Variant Present in the following documents:

• CMMM2014-653487.pdf

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Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Bmc Genomics

Gnad, Florian F; Baucom, Albion A; Mukhyala, Kiran K; Manning, Gerard G; Zhang, Zemin Z

Publication Date: 2013

Variant appearance in text: EGFR: L718P

PubMed Link: 23819521

Variant Present in the following documents:

• 1471-2164-14-S3-S7-S1.xlsx, sheet 2
• 1471-2164-14-S3-S7-S1.xlsx, sheet 1

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The energy landscape analysis of cancer mutations in protein kinases.

Plos One

Dixit, Anshuman A; Verkhivker, Gennady M GM

Publication Date: 2011

Variant appearance in text: EGFR: L718P

PubMed Link: 21998754

Variant Present in the following documents:

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Genetic and expression analysis of HER-2 and EGFR genes in salivary duct carcinoma: empirical and therapeutic significance.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Williams, Michelle D MD; Roberts, Dianna B DB; Kies, Merrill S MS; Mao, Li L; Weber, Randal S RS; El-Naggar, Adel K AK

Publication Date: 2010-04-15

Variant appearance in text: EGFR: L718P

PubMed Link: 20371674

Variant Present in the following documents:

• Main text

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