Variant ID: 7-55241707-GGC-TGA

NM_005228.3(EGFR):c.2155_2157delinsTGA;(p.G719*)

This variant was identified in 916 publications

View GRCh38 version.




Publications:


Lung Cancer Biomarker Speak: Teach Me the Language.

Journal Of The Advanced Practitioner In Oncology
Sandy, Beth B; Morrissette, Jennifer J
Publication Date: 2022-04

Variant appearance in text: EGFR: G719X
PubMed Link: 35663172
Variant Present in the following documents:
  • Main text
  • jadpro-13-302.pdf
View BVdb publication page



Subsequent treatments beyond progression on osimertinib in EGFR-mutated NSCLC and leptomeningeal metastases.

Bmc Medicine
Zheng, Mei-Mei MM; Li, Yang-Si YS; Tu, Hai-Yan HY; Sun, Hao H; Yin, Kai K; Jiang, Ben-Yuan BY; Yang, Jin-Ji JJ; Zhang, Xu-Chao XC; Zhou, Qing Q; Xu, Chong-Rui CR; Wang, Zhen Z; Chen, Hua-Jun HJ; Zhou, De-Xiang DX; Wu, Yi-Long YL
Publication Date: 2022-05-30

Variant appearance in text: EGFR: G719X
PubMed Link: 35644609
Variant Present in the following documents:
  • Main text
  • 12916_2022_Article_2387.pdf
View BVdb publication page



Treatment Strategies for Non-Small Cell Lung Cancer Harboring Common and Uncommon EGFR Mutations: Drug Sensitivity Based on Exon Classification, and Structure-Function Analysis.

Cancers
Kitadai, Rui R; Okuma, Yusuke Y
Publication Date: 2022-05-20

Variant appearance in text: EGFR: G719X
PubMed Link: 35626123
Variant Present in the following documents:
  • Main text
  • cancers-14-02519.pdf
View BVdb publication page



Predicting EGFR mutation, ALK rearrangement, and uncommon EGFR mutation in NSCLC patients by driverless artificial intelligence: a cohort study.

Respiratory Research
Tan, Xueyun X; Li, Yuan Y; Wang, Sufei S; Xia, Hui H; Meng, Rui R; Xu, Juanjuan J; Duan, Yanran Y; Li, Yan Y; Yang, Guanghai G; Ma, Yanling Y; Jin, Yang Y
Publication Date: 2022-05-27

Variant appearance in text: EGFR: G719X
PubMed Link: 35624472
Variant Present in the following documents:
  • Main text
  • 12931_2022_Article_2053.pdf
View BVdb publication page



Genomic Alteration Spectrum of Non-Small Cell Lung Cancer Patients in East-China Characterized by Tumor Tissue DNA and Cell-Free DNA.

Oncotargets And Therapy
Li, Jie J; Chen, Siwen S; Xue, Hui H; Wang, Haoyi H; Huang, Tianwei T; Xie, Hongya H; He, Jiang J; Ke, Cai C; Yu, Zhaonan Z; Ni, Bin B
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35615557
Variant Present in the following documents:
  • Main text
  • ott-15-571.pdf
View BVdb publication page



Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society
Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW
Publication Date: 2022-05-23

Variant appearance in text: EGFR: G719X
PubMed Link: 35606799
Variant Present in the following documents:
  • Main text
  • 41021_2022_Article_248.pdf
  • 41021_2022_248_MOESM1_ESM.xlsx
View BVdb publication page



Afatinib for the Treatment of Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations: An Updated Database of 1023 Cases Brief Report.

Frontiers In Oncology
Yang, James Chih-Hsin JC; Schuler, Martin M; Popat, Sanjay S; Miura, Satoru S; Park, Keunchil K; Passaro, Antonio A; De Marinis, Filippo F; Solca, Flavio F; Märten, Angela A; Kim, Edward S ES
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35574304
Variant Present in the following documents:
  • fonc-12-834704.pdf
View BVdb publication page



Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors.

Nature Communications
Beyett, Tyler S TS; To, Ciric C; Heppner, David E DE; Rana, Jaimin K JK; Schmoker, Anna M AM; Jang, Jaebong J; De Clercq, Dries J H DJH; Gomez, Gabriel G; Scott, David A DA; Gray, Nathanael S NS; Jänne, Pasi A PA; Eck, Michael J MJ
Publication Date: 2022-05-09

Variant appearance in text: EGFR: G719X
PubMed Link: 35534503
Variant Present in the following documents:
  • 41467_2022_Article_30258.pdf
View BVdb publication page



The efficacy of T790M mutation testing in liquid biopsy-Real clinic data.

Plos One
Krawczyk, Paweł P; Grzycka-Kowalczyk, Luiza L; Błach, Justyna J; Reszka, Katarzyna K; Chmielewska, Izabela I; Kieszko, Robert R; Wójcik-Superczyńska, Magdalena M; Szczyrek, Michał M; Jankowski, Tomasz T; Milanowski, Janusz J
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35522668
Variant Present in the following documents:
  • pone.0267846.pdf
View BVdb publication page



Osimertinib-Centered Therapy Against Uncommon Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer- A Mini Review.

Frontiers In Oncology
Song, Chengyang C; Yang, Xueying X
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35494059
Variant Present in the following documents:
  • fonc-12-834585.pdf
View BVdb publication page



Efficacy of liquid biopsy for disease monitoring and early prediction of tumor progression in EGFR mutation-positive non-small cell lung cancer.

Plos One
Ho, Hsiang-Ling HL; Jiang, Yuqiu Y; Chiang, Chi-Lu CL; Karwowska, Sylwia S; Yerram, Ranga R; Sharma, Keerti K; Scudder, Sidney S; Chiu, Chao-Hua CH; Tsai, Chun-Ming CM; Palma, John F JF; Sharma, Abha A; Chou, Teh-Ying TY
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35482671
Variant Present in the following documents:
  • pone.0267362.pdf
View BVdb publication page



Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Bmc Medical Genomics
Sobahy, Turki M TM; Tashkandi, Ghassan G; Bahussain, Donya D; Al-Harbi, Raneem R
Publication Date: 2022-04-25

Variant appearance in text: EGFR: G719X
PubMed Link: 35468810
Variant Present in the following documents:
  • 12920_2022_1235_MOESM2_ESM.xlsx
View BVdb publication page



Exceptional response to afatinib in a patient with persistent G719A EGFR-mutant NSCLC.

Lung Cancer Management
Kulkarni, Amit A AA; Fujioka, Naomi N; Reinhardt, Lucia L; Patel, Manish R MR; Kratzke, Robert A RA
Publication Date: 2022-03

Variant appearance in text: EGFR: G719X
PubMed Link: 35463918
Variant Present in the following documents:
  • lmt-11-54.pdf
View BVdb publication page



Bruceine H Mediates EGFR-TKI Drug Persistence in NSCLC by Notch3-Dependent β-Catenin Activating FOXO3a Signaling.

Frontiers In Oncology
Wu, Jiahui J; He, Xiao X; Xiong, Ziwei Z; Shi, Lingyu L; Chen, Daofeng D; Feng, Yulin Y; Wen, Quan Q
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35463301
Variant Present in the following documents:
  • fonc-12-855603.pdf
View BVdb publication page



Acquired Mechanisms of Resistance to Osimertinib-The Next Challenge.

Cancers
Ríos-Hoyo, Alejandro A; Moliner, Laura L; Arriola, Edurne E
Publication Date: 2022-04-12

Variant appearance in text: EGFR: G719X
PubMed Link: 35454838
Variant Present in the following documents:
  • cancers-14-01931.pdf
View BVdb publication page



The Clinically Actionable Molecular Profile of Early versus Late-Stage Non-Small Cell Lung Cancer, an Individual Age and Sex Propensity-Matched Pair Analysis.

Current Oncology (Toronto, Ont.)
McGuire, Anna L AL; McConechy, Melissa K MK; Melosky, Barb L BL; English, John C JC; Choi, James J JJ; Peng, Defen D; Yee, John J; Furman, Benjamin L S BLS; Aguirre Hernandez, Rosalia R; Feijao, Pedro P; Mulder, David D; Hughesman, Curtis C; Yip, Stephen S
Publication Date: 2022-04-11

Variant appearance in text: EGFR: G719X
PubMed Link: 35448189
Variant Present in the following documents:
  • curroncol-29-00215.pdf
View BVdb publication page



TP53 Co-Mutations in Advanced EGFR-Mutated Non-Small Cell Lung Cancer: Prognosis and Therapeutic Strategy for Cancer Therapy.

Frontiers In Oncology
Liu, Surui S; Yu, Jin J; Zhang, Hui H; Liu, Jie J
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35444951
Variant Present in the following documents:
  • fonc-12-860563.pdf
View BVdb publication page



Observational study of rebiopsy in EGFR-TKI-resistant patients with EGFR mutation-positive advanced NSCLC.

Scientific Reports
Koyama, Kenichi K; Miura, Satoru S; Watanabe, Satoshi S; Shoji, Satoshi S; Koshio, Jun J; Hayashi, Yoshiki Y; Ishikawa, Daisuke D; Sato, Ko K; Miyabayashi, Takao T; Okajima, Masaaki M; Ota, Takeshi T; Tanaka, Tomohiro T; Matsumoto, Naoya N; Kuriyama, Hideyuki H; Abe, Tetsuya T; Nozaki, Koichiro K; Ichikawa, Kosuke K; Kondo, Rie R; Tanaka, Hiroshi H; Kikuchi, Toshiaki T
Publication Date: 2022-04-16

Variant appearance in text: EGFR: G719X
PubMed Link: 35430596
Variant Present in the following documents:
  • 41598_2022_Article_10288.pdf
View BVdb publication page



EGFR exon 20 insertion mutations in advanced non-small-cell lung cancer: current status and perspectives.

Biomarker Research
Hou, Jiabao J; Li, Hongle H; Ma, Shuxiang S; He, Zhen Z; Yang, Sen S; Hao, Lidan L; Zhou, Hanqiong H; Zhang, Zhe Z; Han, Jing J; Wang, Li L; Wang, Qiming Q
Publication Date: 2022-04-13

Variant appearance in text: EGFR: G719X
PubMed Link: 35418149
Variant Present in the following documents:
  • 40364_2022_Article_372.pdf
View BVdb publication page



Clinical efficacy of dacomitinib in rechallenge setting for patients with epidermal growth factor receptor mutant non-small cell lung cancer: A multicenter retrospective analysis (TOPGAN2020-02).

Thoracic Cancer
Tanaka, Hisashi H; Sakamoto, Hiroaki H; Akita, Takahiro T; Ohyanagi, Fumiyoshi F; Kawashima, Yosuke Y; Tambo, Yuichi Y; Tanimoto, Azusa A; Horiike, Atsushi A; Miyauchi, Eisaku E; Tsuchiya-Kawano, Yuko Y; Yanagitani, Noriko N; Nishio, Makoto M
Publication Date: 2022-04-12

Variant appearance in text: EGFR: G719X
PubMed Link: 35415873
Variant Present in the following documents:
  • Main text
  • TCA-13-1471.pdf
View BVdb publication page



Overview on Molecular Biomarkers for Laryngeal Cancer: Looking for New Answers to an Old Problem.

Cancers
Falco, Michela M; Tammaro, Chiara C; Takeuchi, Takashi T; Cossu, Alessia Maria AM; Scafuro, Giuseppe G; Zappavigna, Silvia S; Itro, Annalisa A; Addeo, Raffaele R; Scrima, Marianna M; Lombardi, Angela A; Ricciardiello, Filippo F; Irace, Carlo C; Caraglia, Michele M; Misso, Gabriella G
Publication Date: 2022-03-28

Variant appearance in text: EGFR: G719X
PubMed Link: 35406495
Variant Present in the following documents:
  • cancers-14-01716.pdf
View BVdb publication page



Prognostic Value of Albumin-to-Alkaline Phosphatase Ratio for EGFR-Mutated Advanced Non-Small-Cell Lung Cancer Patients Treated with First-Line EGFR-TKIs: A Large Population-Based Study and Literature Review.

International Journal Of General Medicine
Gan, Yuncui Y; Ren, Jing J; Xian, Jinghong J; Yu, He H; Jin, Jing J; Li, Dan D; Li, Weimin W
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35378914
Variant Present in the following documents:
  • ijgm-15-3405.pdf
View BVdb publication page



Overexpression of CEACAM6 activates Src-FAK signaling and inhibits anoikis, through homophilic interactions in lung adenocarcinomas.

Translational Oncology
Kim, Eun Young EY; Cha, Yoon Jin YJ; Jeong, Sukin S; Chang, Yoon Soo YS
Publication Date: 2022-03-28

Variant appearance in text: EGFR: G719X
PubMed Link: 35358791
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



[Targeted Therapy and Mechanism of Drug Resistance in Non-small Cell Lung Cancer 
with Epidermal Growth Factor Receptor Gene Mutation].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Huang, Junxia J; Wang, Hong H
Publication Date: 2022-03-20

Variant appearance in text: EGFR: G719X
PubMed Link: 35340161
Variant Present in the following documents:
  • zgfazz-25-3-183.pdf
View BVdb publication page



[Clinical Characteristics and Prognosis of 76 Lung Adenocarcinoma Patients 
Harboring EGFR Mutations with Pleural Effusion at Initial Diagnosis: 
A Single-center Retrospective Study].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Yin, Wencheng W; Zhang, Hua H; Gu, Yangchun Y; Yi, Fumei F; Li, Qian Q; Liu, Yan'e Y; Yao, Yanhong Y; Liu, Zhentao Z; Cao, Baoshan B
Publication Date: 2022-03-20

Variant appearance in text: EGFR: G719X
PubMed Link: 35340158
Variant Present in the following documents:
  • zgfazz-25-3-156.pdf
View BVdb publication page



Prognostic Values of Inflammatory Indexes and Clinical Factors in Patients with Epidermal Growth Factor Receptor Mutations in Lung Adenocarcinoma and Treated with Tyrosine Kinase Inhibitors.

Journal Of Personalized Medicine
Chang, Bee-Song BS; Peng, Tai-Chu TC; Wu, Yi-Feng YF; Hsieh, Tsung-Cheng TC; Huang, Chun-Hou CH
Publication Date: 2022-03-05

Variant appearance in text: EGFR: G719X
PubMed Link: 35330404
Variant Present in the following documents:
  • jpm-12-00404.pdf
View BVdb publication page



Clinicopathological and Molecular Features of Secondary Cancer (Metastasis) to the Thyroid and Advances in Management.

International Journal Of Molecular Sciences
Nguyen, Marie M; He, George G; Lam, Alfred King-Yin AK
Publication Date: 2022-03-17

Variant appearance in text: EGFR: G719X
PubMed Link: 35328664
Variant Present in the following documents:
  • ijms-23-03242.pdf
View BVdb publication page



Effect of Osimertinib on CTCs and ctDNA in EGFR Mutant Non-Small Cell Lung Cancer Patients: The Prognostic Relevance of Liquid Biopsy.

Cancers
Kallergi, Galatea G; Kontopodis, Emmanouil E; Ntzifa, Aliki A; Jordana-Ariza, Núria N; Karachaliou, Niki N; Pantazaka, Evangelia E; Charalambous, Haris A HA; Psyrri, Amanda A; Tsaroucha, Emily E; Boukovinas, Ioannis I; Koumarianou, Anna A; Hatzidaki, Dora D; Lianidou, Evi E; Georgoulias, Vassilis V; Rosell, Rafael R; Kotsakis, Athanasios A
Publication Date: 2022-03-19

Variant appearance in text: EGFR: G719X
PubMed Link: 35326725
Variant Present in the following documents:
  • cancers-14-01574.pdf
View BVdb publication page



Genomic Landscape of Non-Small Cell Lung Cancer (NSCLC) in East Asia Using Circulating Tumor DNA (ctDNA) in Clinical Practice.

Current Oncology (Toronto, Ont.)
Cho, Byoung Chul BC; Loong, Herbert H F HHF; Tsai, Chun-Ming CM; Teo, Man Lung P MLP; Kim, Hye Ryun HR; Lim, Sun Min SM; Jain, Suyog S; Olsen, Steve S; Park, Keunchil K
Publication Date: 2022-03-21

Variant appearance in text: EGFR: G719X
PubMed Link: 35323374
Variant Present in the following documents:
  • curroncol-29-00174.pdf
View BVdb publication page



Two Unusual Mutations in the Epidermal Growth Factor Receptor Gene in a Patient With Lung Adenocarcinoma.

Cureus
Zapata Laguado, Martin M; Zuluaga, Andrea A; Parra Medina, Rafael R; Bruges, Ricardo R
Publication Date: 2022-02

Variant appearance in text: EGFR: G719x
PubMed Link: 35321064
Variant Present in the following documents:
  • cureus-0014-00000022372.pdf
View BVdb publication page



Efficacy of EGFR-TKI sequential therapy in patients with EGFR exon 19 insertion-positive non-small-cell lung cancer: A case report.

World Journal Of Clinical Cases
Shan, Bin-Bin BB; Li, Yuan Y; Zhao, Chang C; An, Xiao-Qin XQ; Zhang, Quan-Mao QM
Publication Date: 2022-02-26

Variant appearance in text: EGFR: G719X
PubMed Link: 35317151
Variant Present in the following documents:
  • WJCC-10-1883.pdf
View BVdb publication page



PEAC: An Ultrasensitive and Cost-Effective MRD Detection System in Non-small Cell Lung Cancer Using Plasma Specimen.

Frontiers In Medicine
Xu, Jianping J; Pu, Yue Y; Lin, Rui R; Xiao, Shanshan S; Fu, Yingxue Y; Wang, Tao T
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35308511
Variant Present in the following documents:
  • fmed-09-822200.pdf
View BVdb publication page



Rationale and design of a phase II trial of dacomitinib in advanced non-small cell lung cancer patients with uncommon epidermal growth factor receptor mutations: a prospective and single arm study (DANCE study).

Bmc Cancer
Zhang, Bo B; Shi, Chunlei C; Gao, Zhiqiang Z; Zhong, Hua H; Xiong, Liwen L; Gu, Aiqin A; Wang, Weimin W; Chu, Tianqing T; Zhang, Wei W; Wang, Huimin H; Zhang, Xueyan X; Zhong, Runbo R; Han, Baohui B
Publication Date: 2022-03-19

Variant appearance in text: EGFR: G719X
PubMed Link: 35305596
Variant Present in the following documents:
  • 12885_2022_Article_9409.pdf
View BVdb publication page



Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-03-19

Variant appearance in text: EGFR: G719X
PubMed Link: 35304574
Variant Present in the following documents:
  • 41388_2022_Article_2263.pdf
View BVdb publication page



Efficacy of Prophylactic Traditional Chinese Medicine on Skin Toxicity of Afatinib in EGFR Mutation-Positive Advanced Lung Adenocarcinoma: A Single-Center, Prospective, Double-Blinded, Randomized-Controlled Pilot Trial.

Integrative Cancer Therapies
Li, Chia-Ling CL; Hsia, Te-Chun TC; Yang, Su-Tso ST; Chao, Kun-San Clifford KC; Tu, Chih-Yen CY; Chen, Hung-Jen HJ; Li, Chia-Hsiang CH
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35297709
Variant Present in the following documents:
  • 10.1177_15347354221086663.pdf
View BVdb publication page



Case Report: Opportunities and Challenges of Immunotherapy in Heavily-Treated EGFR-Mutant Advanced Squamous Cell Lung Carcinoma After Progression on EGFR-TKIs and Chemotherapy.

Frontiers In Oncology
Jin, Wei W; Wang, Xin X; Wang, Jie J; Lin, Lin L
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35296008
Variant Present in the following documents:
  • fonc-12-820408.pdf
View BVdb publication page



ADAURA: The Splash of Osimertinib in Adjuvant EGFR-Mutant Non-small Cell Lung Cancer.

Oncology And Therapy
Ortega-Franco, Ana A; Rafee, Shereen S
Publication Date: 2022-03-16

Variant appearance in text: EGFR: G719X
PubMed Link: 35294773
Variant Present in the following documents:
  • 40487_2022_Article_190.pdf
View BVdb publication page



Tyrosine Kinase Inhibitor Activity in Patients with NSCLC Harboring Uncommon EGFR Mutations: A Retrospective International Cohort Study (UpSwinG).

The Oncologist
Popat, Sanjay S; Hsia, Te-Chun TC; Hung, Jen-Yu JY; Jung, Hyun Ae HA; Shih, Jin-Yuan JY; Park, Cheol Kyu CK; Lee, Seung Hyeun SH; Okamoto, Tatsuro T; Ahn, Hee Kyung HK; Lee, Yong Chul YC; Sato, Yuki Y; Lee, Sung Sook SS; Mascaux, Celine C; Daoud, Hasan H; Märten, Angela A; Miura, Satoru S
Publication Date: 2022-03-11

Variant appearance in text: EGFR: G719X
PubMed Link: 35274704
Variant Present in the following documents:
  • oyac022.pdf
View BVdb publication page



The Role of TP53 Mutations in EGFR-Mutated Non-Small-Cell Lung Cancer: Clinical Significance and Implications for Therapy.

Cancers
Canale, Matteo M; Andrikou, Kalliopi K; Priano, Ilaria I; Cravero, Paola P; Pasini, Luigi L; Urbini, Milena M; Delmonte, Angelo A; Crinò, Lucio L; Bronte, Giuseppe G; Ulivi, Paola P
Publication Date: 2022-02-23

Variant appearance in text: EGFR: G719X
PubMed Link: 35267450
Variant Present in the following documents:
  • cancers-14-01143.pdf
View BVdb publication page



Development and Validation of a Concise Prediction Scoring System for Asian Lung Cancer Patients with EGFR Mutation Before Treatment.

Technology In Cancer Research & Treatment
An, Wenting W; Fan, Wei W; Zhong, Feiyang F; Wang, Binchen B; Wang, Shan S; Gan, Tian T; Tian, Sufang S; Liao, Meiyan M
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35234540
Variant Present in the following documents:
  • 10.1177_15330338221078732.pdf
View BVdb publication page



The Lifted Veil of Uncommon EGFR Mutation p.L747P in Non-Small Cell Lung Cancer: Molecular Feature and Targeting Sensitivity to Tyrosine Kinase Inhibitors.

Frontiers In Oncology
Yang, Guangjian G; Liu, Chengming C; Hu, Jiaqi J; Sun, Yang Y; Hu, Peizeng P; Liu, Liu L; Xu, Haiyan H; Li, Dazhou D; Li, Weihua W; Yang, Yaning Y; Sun, Nan N; He, Jie J; Wang, Yan Y
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35223527
Variant Present in the following documents:
  • fonc-12-843299.pdf
View BVdb publication page



Outcomes in Patients With Lung Adenocarcinoma With Transformation to Small Cell Lung Cancer After EGFR Tyrosine Kinase Inhibitors Resistance: A Systematic Review and Pooled Analysis.

Frontiers In Oncology
Xu, Jinhe J; Xu, Lihuan L; Wang, Baoshan B; Kong, Wencui W; Chen, Ying Y; Yu, Zongyang Z
Publication Date: 2021

Variant appearance in text: EGFR: G719X
PubMed Link: 35223450
Variant Present in the following documents:
  • fonc-11-766148.pdf
View BVdb publication page



Clinical Utility of Plasma Cell-Free DNA EGFR Mutation Analysis in Treatment-Naïve Stage IV Non-Small Cell Lung Cancer Patients.

Journal Of Clinical Medicine
Kim, Bo-Guen BG; Jang, Ja-Hyun JH; Kim, Jong-Won JW; Shin, Sun Hye SH; Jeong, Byeong-Ho BH; Lee, Kyungjong K; Kim, Hojoong H; Kwon, O Jung OJ; Ahn, Myung-Ju MJ; Um, Sang-Won SW
Publication Date: 2022-02-21

Variant appearance in text: EGFR: G719X
PubMed Link: 35207417
Variant Present in the following documents:
  • jcm-11-01144.pdf
View BVdb publication page



Clinical outcomes of advanced non-small cell lung cancer patients harboring distinct subtypes of EGFR mutations and receiving first-line tyrosine kinase inhibitors: brain metastasis and de novo T790M matters.

Bmc Cancer
Zeng, Ya Y; Guo, Tiantian T; Zhou, Yue Y; Zhao, Yang Y; Chu, Li L; Chu, Xiao X; Yang, Xi X; Ni, Jianjiao J; Zhu, Zhengfei Z
Publication Date: 2022-02-21

Variant appearance in text: EGFR: G719X
PubMed Link: 35189835
Variant Present in the following documents:
  • 12885_2022_Article_9245.pdf
View BVdb publication page



Identifying Actionable Variants Using Capture-Based Targeted Sequencing in 563 Patients With Non-Small Cell Lung Carcinoma.

Frontiers In Oncology
Jiang, Haiping H; Wang, Yinan Y; Xu, Hanlin H; Lei, Wei W; Yu, Xiaoyun X; Tian, Haiying H; Meng, Cong C; Wang, Xueying X; Zhao, Zicheng Z; Jin, Xiangfeng X
Publication Date: 2021

Variant appearance in text: EGFR: G719X
PubMed Link: 35186718
Variant Present in the following documents:
  • fonc-11-812433.pdf
View BVdb publication page



Treatment patterns, testing practices, and outcomes in the pre-FLAURA era for patients with EGFR mutation-positive advanced NSCLC: a retrospective chart review (REFLECT).

Therapeutic Advances In Medical Oncology
Addeo, Alfredo A; Hochmair, Maximilian M; Janzic, Urska U; Dudnik, Elizabeth E; Charpidou, Andriani A; Płużański, Adam A; Ciuleanu, Tudor T; Donev, Ivan Shterev IS; Elbaz, Judith J; Aarøe, Jørgen J; Ott, René R; Peled, Nir N
Publication Date: 2021

Variant appearance in text: EGFR: G719X
PubMed Link: 35173817
Variant Present in the following documents:
  • Main text
  • 10.1177_17588359211059874.pdf
View BVdb publication page



Fluorescence Imaging of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance in Non-Small Cell Lung Cancer.

Cancers
Martin-Fernandez, Marisa L ML
Publication Date: 2022-01-28

Variant appearance in text: EGFR: G719X
PubMed Link: 35158954
Variant Present in the following documents:
  • Main text
  • cancers-14-00686.pdf
View BVdb publication page



Cytology-Based Specimen Triage for Epidermal Growth Factor Receptor Mutation Testing of Malignant Pleural Effusions in Non-Small Cell Lung Cancer.

Frontiers In Oncology
Chiang, Chi-Lu CL; Shen, Chia-I CI; Huang, Hsu-Ching HC; Chang, Han-Jhih HJ; Huang, Yu-Ting YT; Chiu, Chao-Hua CH
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35141163
Variant Present in the following documents:
  • Main text
  • fonc-12-810124.pdf
View BVdb publication page



Co-occurrence CDK4/6 amplification serves as biomarkers of de novo EGFR TKI resistance in sensitizing EGFR mutation non-small cell lung cancer.

Scientific Reports
Sitthideatphaiboon, Piyada P; Teerapakpinyo, Chinachote C; Korphaisarn, Krittiya K; Leelayuwatanakul, Nophol N; Pornpatrananrak, Nopporn N; Poungvarin, Naravat N; Chantranuwat, Poonchavist P; Shuangshoti, Shanop S; Aporntewan, Chatchawit C; Chintanapakdee, Wariya W; Sriuranpong, Virote V; Vinayanuwattikun, Chanida C
Publication Date: 2022-02-09

Variant appearance in text: EGFR: G719X
PubMed Link: 35140316
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_6239.pdf
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The Role of Circulating Biomarkers in Lung Cancer.

Frontiers In Oncology
Herath, Sayuri S; Sadeghi Rad, Habib H; Radfar, Payar P; Ladwa, Rahul R; Warkiani, Majid M; O'Byrne, Ken K; Kulasinghe, Arutha A
Publication Date: 2021

Variant appearance in text: EGFR: G719X
PubMed Link: 35127511
Variant Present in the following documents:
  • Main text
  • fonc-11-801269.pdf
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The clinicopathological study of lung cancer concealed in end-stage of interstitial lung disease.

Translational Cancer Research
Wang, Bei B; Zhang, Xiaoyan X; Chen, Huang H; Yang, Lei L; Li, Jie J; Xiao, Fei F; Liang, Chaoyang C; Zhong, Dingrong D
Publication Date: 2020-02

Variant appearance in text: EGFR: G719X
PubMed Link: 35117398
Variant Present in the following documents:
  • Main text
  • tcr-09-02-536.pdf
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EGFR first- and second-generation TKIs-there is still place for them in EGFR-mutant NSCLC patients.

Translational Cancer Research
Karachaliou, Niki N; Fernandez-Bruno, Manuel M; Bracht, Jillian Wilhelmina Paulina JWP; Rosell, Rafael R
Publication Date: 2019-01

Variant appearance in text: EGFR: G719X
PubMed Link: 35117062
Variant Present in the following documents:
  • Main text
  • tcr-08-S1-S23.pdf
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Effect of icotinib on advanced lung adenocarcinoma patients with sensitive EGFR mutation detected in ctDNA by ddPCR.

Translational Cancer Research
Chen, Hua-Fei HF; Lei, Lei L; Wu, Li-Xin LX; Li, Xiao-Feng XF; Zhang, Qu-Xia QX; Pan, Wei-Wei WW; Min, Yong-Hua YH; Zhu, You-Cai YC; Du, Kai-Qi KQ; Wang, Min M; Wang, Wen-Xian WX; Xu, Chun-Wei CW
Publication Date: 2019-12

Variant appearance in text: EGFR: G719X
PubMed Link: 35117043
Variant Present in the following documents:
  • Main text
  • tcr-08-08-2858.pdf
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Analysis of real-word mutations of lung cancer driver genes in five regions of China.

Translational Cancer Research
Sun, Mengyao M; Guo, Ye Y; Shao, Guoguang G; Duan, Xiumei X; Yang, Zhiguang Z; Zhang, Peng P; Liu, Yunpeng Y; Dong, Yutong Y; Wang, Xu X; Xu, Yinghui Y; Sun, Chao C; Ma, Kewei K
Publication Date: 2019-11

Variant appearance in text: EGFR: G719X
PubMed Link: 35117015
Variant Present in the following documents:
  • Main text
  • tcr-08-07-2581.pdf
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Carcinoembryonic antigen in pleural effusion of patients with lung adenocarcinoma: a predictive marker for EGFR mutation.

Translational Cancer Research
Lv, Yan-Ling YL; Liu, Hong-Bing HB; Yuan, Dong-Mei DM; Zhou, Li L; Jin, Shu-Xian SX; Song, Yong Y
Publication Date: 2019-08

Variant appearance in text: EGFR: G719X
PubMed Link: 35116846
Variant Present in the following documents:
  • Main text
  • tcr-08-04-1027.pdf
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The clinical value of circulating tumor DNA detection in advanced non-small cell lung cancer.

Translational Cancer Research
Lin, Xiao X; Dong, Wentao W; Lai, Xiaojing X; Feng, Wei W; Yu, Xiaofu X; Gu, Qing Q; Wang, Chunyang C; Xiao, Wen W; Zheng, Xiao X
Publication Date: 2019-02

Variant appearance in text: EGFR: G719X
PubMed Link: 35116746
Variant Present in the following documents:
  • Main text
  • tcr-08-01-170.pdf
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Clinical Features and Surgical Treatment of Synchronous Multiple Primary Lung Adenocarcinomas With Different EGFR Mutations.

Frontiers In Oncology
Qu, Rirong R; Ye, Fan F; Tu, Dehao D; Cai, Yixin Y; Fu, Xiangning X
Publication Date: 2021

Variant appearance in text: EGFR: G719X
PubMed Link: 35096585
Variant Present in the following documents:
  • fonc-11-785777.pdf
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First-line osimertinib treatment in a patient with lung adenocarcinoma with coexisting epidermal growth factor receptor G719S and de novo T790M mutations.

Thoracic Cancer
Ito, Noriaki N; Masuda, Takeshi T; Ooka, Ikuko I; Hosoya, Takatsune T; Yamaguchi, Kakuhiro K; Sakamoto, Shinjiro S; Horimasu, Yasushi Y; Nakashima, Taku T; Miyamoto, Shintaro S; Iwamoto, Hiroshi H; Fujitaka, Kazunori K; Hamada, Hironobu H; Hattori, Noboru N
Publication Date: 2022-01-25

Variant appearance in text: EGFR: G719X
PubMed Link: 35076999
Variant Present in the following documents:
  • TCA-13-771.pdf
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Lung squamous cell carcinoma with rare epidermal growth factor receptor mutation G719X: a case report and literature review.

Annals Of Translational Medicine
Bi, Huanhuan H; Ren, Dunqiang D; Wu, Jieqiong J; Ding, Xiaoqian X; Guo, Caihong C; Miura, Satoru S; Megyesfalvi, Zsolt Z; Arulananda, Surein S; Wang, Hongmei H
Publication Date: 2021-12

Variant appearance in text: EGFR: G719X
PubMed Link: 35071499
Variant Present in the following documents:
  • Main text
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Real-world experience of afatinib as first-line therapy for advanced EGFR mutation-positive non-small cell lung cancer in Korea.

Translational Lung Cancer Research
Lee, Sung Yong SY; Choi, Chang-Min CM; Chang, Yoon Soo YS; Lee, Kye Young KY; Kim, Seung Joon SJ; Yang, Sei Hoon SH; Ryu, Jeong Seon JS; Lee, Jeong Eun JE; Lee, Shin Yup SY; Park, Ji Young JY; Kim, Young-Chul YC; Oh, In-Jae IJ; Jung, Chi Young CY; Lee, Sang Hoon SH; Yoon, Seong Hoon SH; Choi, Juwhan J; Jang, Tae Won TW
Publication Date: 2021-12

Variant appearance in text: EGFR: G719X
PubMed Link: 35070746
Variant Present in the following documents:
  • Main text
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Prevalence of targeted therapy-related genetic variations in NSCLC and their relationship with clinicopathological characteristics.

Plos One
Li, Fanghua F; Ye, Peng P; Cai, Peiling P; Dong, Dandan D; Zhang, Yihao Y; Yang, Yue Y; Sun, Xingwang X
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 35061839
Variant Present in the following documents:
  • Main text
  • pone.0262822.pdf
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Use of Circulating Tumour DNA (ctDNA) for Measurement of Therapy Predictive Biomarkers in Patients with Cancer.

Journal Of Personalized Medicine
Duffy, Michael J MJ; Crown, John J
Publication Date: 2022-01-13

Variant appearance in text: EGFR: G719X
PubMed Link: 35055414
Variant Present in the following documents:
  • Main text
  • jpm-12-00099.pdf
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Systemic Inflammation Index and Tumor Glycolytic Heterogeneity Help Risk Stratify Patients with Advanced Epidermal Growth Factor Receptor-Mutated Lung Adenocarcinoma Treated with Tyrosine Kinase Inhibitor Therapy.

Cancers
Lue, Kun-Han KH; Huang, Chun-Hou CH; Hsieh, Tsung-Cheng TC; Liu, Shu-Hsin SH; Wu, Yi-Feng YF; Chen, Yu-Hung YH
Publication Date: 2022-01-08

Variant appearance in text: EGFR: G719X
PubMed Link: 35053473
Variant Present in the following documents:
  • Main text
  • cancers-14-00309.pdf
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Uncommon EGFR Compound Mutations in Non-Small Cell Lung Cancer (NSCLC): A Systematic Review of Available Evidence.

Current Oncology (Toronto, Ont.)
Attili, Ilaria I; Passaro, Antonio A; Pisapia, Pasquale P; Malapelle, Umberto U; de Marinis, Filippo F
Publication Date: 2022-01-09

Variant appearance in text: EGFR: G719X
PubMed Link: 35049698
Variant Present in the following documents:
  • Main text
  • curroncol-29-00024.pdf
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A real-world study of dacomitinib in later-line settings for advanced non-small cell lung cancer patients harboring EGFR mutations.

Cancer Medicine
Li, Hong-Shuai HS; Zhang, Jin-Yao JY; Yan, Xiang X; Xu, Hai-Yan HY; Hao, Xue-Zhi XZ; Xing, Pu-Yuan PY; Wang, Yan Y
Publication Date: 2022-01-12

Variant appearance in text: EGFR: G719X
PubMed Link: 35023313
Variant Present in the following documents:
  • CAM4-11-1026.pdf
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A Phase IIIb Open-Label, Single-Arm Study of Afatinib in EGFR TKI-Naïve Patients with EGFRm+ NSCLC: Final Analysis, with a Focus on Patients Enrolled at Sites in China.

Targeted Oncology
Tu, Hai-Yan HY; Feng, Jifeng J; Shi, Meiqi M; Zhao, Jun J; Wang, Yuyan Y; Chang, Jianhua J; Wang, Jialei J; Cheng, Ying Y; Zhu, Jing J; Tan, Eng-Huat EH; Li, Kai K; Zhang, Yiping Y; Lee, Victor V; Yang, Cheng-Ta CT; Su, Wu-Chou WC; Lam, David Chi-Leung DC; Srinivasa, B J BJ; Rajappa, Senthil S; Ho, Ching-Liang CL; Lam, Kwok Chi KC; Hu, Yi Y; Bondarde, Shailesh Arjun SA; Liu, Xiaoqing X; Tian, Yahui Y; Xue, Zhiyi Z; Cseh, Agnieszka A; Huang, Dennis Chin-Lun DC; Zhou, Caicun C; Wu, Yi-Long YL
Publication Date: 2022-01-12

Variant appearance in text: EGFR: G719X
PubMed Link: 35020119
Variant Present in the following documents:
  • Main text
  • 11523_2021_Article_859.pdf
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Biomarker Testing in Older Patients Treated for an Advanced or Metastatic Non-Squamous Non-Small-Cell Lung Cancer: The French ESME Real-Life Multicenter Cohort Experience.

Cancers
Lamy, Tina T; Cabarrou, Bastien B; Planchard, David D; Quantin, Xavier X; Schneider, Sophie S; Bringuier, Michael M; Besse, Benjamin B; Girard, Nicolas N; Chouaid, Christos C; Filleron, Thomas T; Simon, Gaëtane G; Baldini, Capucine C
Publication Date: 2021-12-24

Variant appearance in text: EGFR: G719X
PubMed Link: 35008257
Variant Present in the following documents:
  • Main text
  • cancers-14-00092.pdf
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Role of the EGFR-KDD mutation as a possible mechanism of acquired resistance of non-small cell lung cancer to EGFR tyrosine kinase inhibitors: A case report.

Molecular And Clinical Oncology
He, Cheng C; Wang, Yong Y
Publication Date: 2022-02

Variant appearance in text: EGFR: G719X
PubMed Link: 34987800
Variant Present in the following documents:
  • Main text
  • mco-16-02-02463.pdf
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Therapeutic advances in non-small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy.

Medcomm
Cheng, Yuan Y; Zhang, Tao T; Xu, Qing Q
Publication Date: 2021-12

Variant appearance in text: EGFR: G719X
PubMed Link: 34977873
Variant Present in the following documents:
  • MCO2-2-692.pdf
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Real-World Survival Outcomes Based on EGFR Mutation Status in Chinese Patients With Lung Adenocarcinoma After Complete Resection: Results From the ICAN Study.

Jto Clinical And Research Reports
Yang, Xue-Ning XN; Yan, Hong-Hong HH; Wang, Jun J; Chu, Xiang-Yang XY; Liu, Zhi-Dong ZD; Shen, Yi Y; Ma, Hai-Tao HT; Fu, Xiang-Ning XN; Hu, Jian J; Zhou, Nai-Kang NK; Liu, Yong-Yu YY; Zhou, Xin-Ming XM; Li, Jing-Song JS; Yang, Kang K; Li, Jian J; Xu, Lin L; Wang, Si-Yu SY; Wang, Qun Q; Liu, Lun-Xu LX; Xu, Shun S; Chen, Zhong-Yuan ZY; Lou, Hong-He HH; Wang, Chang-Li CL; Cheng, Ying Y; Liu, Si-Yang SY; Zhang, Xu-Chao XC; Zhong, Wen-Zhao WZ; Wu, Yi-Long YL
Publication Date: 2022-01

Variant appearance in text: EGFR: G719X
PubMed Link: 34977823
Variant Present in the following documents:
  • Main text
  • main.pdf
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Recent Research Progress of Chiral Small Molecular Antitumor-Targeted Drugs Approved by the FDA From 2011 to 2019.

Frontiers In Oncology
Chu, Xuetong X; Bu, Yizhi Y; Yang, Xiaoping X
Publication Date: 2021

Variant appearance in text: EGFR: G719X
PubMed Link: 34976824
Variant Present in the following documents:
  • Main text
  • fonc-11-785855.pdf
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A Computed Tomography-Derived Radiomics Approach for Predicting Uncommon EGFR Mutation in Patients With NSCLC.

Frontiers In Oncology
Chen, Wufei W; Hua, Yanqing Y; Mao, Dingbiao D; Wu, Hao H; Tan, Mingyu M; Ma, Weiling W; Huang, Xuemei X; Lu, Jinjuan J; Li, Cheng C; Li, Ming M
Publication Date: 2021

Variant appearance in text: EGFR: G719X
PubMed Link: 34976788
Variant Present in the following documents:
  • Main text
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