EGFR c.2155_2157delinsTGA ;(p.G719*)

Variant ID: 7-55241707-GGC-TGA

NM_005228.3(EGFR):c.2155_2157delinsTGA;(p.G719*)

This variant was identified in 953 publications

View GRCh38 version.




Publications:


Clinical and prognostic significance of detecting CEA, EGFR, LunX, c-met and EpCAM mRNA-positive cells in the peripheral blood, tumor-draining blood and bone marrow of non-small cell lung cancer patients.

Translational Lung Cancer Research
Rehulkova, Alona A; Chudacek, Josef J; Prokopova, Andrea A; Vidlarova, Monika M; Stranska, Jana J; Drabek, Jiri J; Potockova, Jana J; Trojanec, Radek R; Vrbkova, Jana J; Skarda, Josef J; Bohanes, Tomas T; Szkorupa, Marek M; Tolmaci, Benjamin B; Klein, Jiri J; Srovnal, Josef J; Hajduch, Marian M
Publication Date: 2023-05-31

Variant appearance in text: EGFR: G719X
PubMed Link: 37323172
Variant Present in the following documents:
  • Main text
  • tlcr-12-05-1034.pdf
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EGFR p.V774M/p.L833V compound mutations in lung adenocarcinoma responded well to almonertinib: a case report.

Frontiers In Oncology
Pan, Hai H; Zhang, Linlin L; Meng, Fanlu F; Guan, Shasha S; Zhong, Diansheng D
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 37251951
Variant Present in the following documents:
  • Main text
  • fonc-13-1159308.pdf
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Overview on Therapeutic Options in Uncommon EGFR Mutant Non-Small Cell Lung Cancer (NSCLC): New Lights for an Unmet Medical Need.

International Journal Of Molecular Sciences
Pretelli, Giulia G; Spagnolo, Calogera Claudia CC; Ciappina, Giuliana G; Santarpia, Mariacarmela M; Pasello, Giulia G
Publication Date: 2023-05-17

Variant appearance in text: EGFR: G719X
PubMed Link: 37240224
Variant Present in the following documents:
  • Main text
  • ijms-24-08878.pdf
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The Role of Neutrophil-to-Lymphocyte Ratio in Advanced EGFR-Mutant NSCLC Patients Treated with First-Line Osimertinib.

Oncotargets And Therapy
Chen, Kuan-Chih KC; Huang, Yen-Hsiang YH; Hsu, Kuo-Hsuan KH; Tseng, Jeng-Sen JS; Chang, Gee-Chen GC; Yang, Tsung-Ying TY
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 37220494
Variant Present in the following documents:
  • Main text
  • ott-16-317.pdf
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Updating the Targeted Therapy Paradigm for Patients With Metastatic NSCLC.

Journal Of The Advanced Practitioner In Oncology
Florez Duma, Narjust N; Mcdonald, Stephanie S
Publication Date: 2023-04

Variant appearance in text: EGFR: G719X
PubMed Link: 37197732
Variant Present in the following documents:
  • Main text
  • jadpro-14-241.pdf
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Advanced Non-small Cell Lung Cancer: EGFR Mutation Analysis Using Pyrosequencing and the Fully Automated qPCR-Based IdyllaTM System.

Cancer Control : Journal Of The Moffitt Cancer Center
Boustany, Youssra Y; Laraqui, Abdelilah A; El Zaitouni, Sara S; Ghaouti, Merieme M; Benzekri, Asmae A; Kettani, Fouad F; Oukabli, Mohammed M; Ennibi, Khalid K; Belkadi, Bouchra B; Sekhsokh, Yassine Y
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 37196225
Variant Present in the following documents:
  • Main text
  • 10.1177_10732748231177538.pdf
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CRAC (Clinical Relevance of Alterations in Cancer): a Knowledge Base for the Selection of Molecularly Matched Therapy for Solid Tumors.

Sovremennye Tekhnologii V Meditsine
Lebedeva, A A AA; Kavun, A I AI; Veselovsky, E M EM; Mileyko, V A VA; Ivanov, M V MV
Publication Date: 2022

Variant appearance in text: EGFR: G719X
PubMed Link: 37181287
Variant Present in the following documents:
  • Main text
  • STM-14-6-02.pdf
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Performance of Ultra-Rapid Idylla™ EGFR Mutation Test in Non-Small-Cell Lung Cancer and Its Potential at Clinical Molecular Screening.

Cancers
Suda, Kenichi K; Sakai, Kazuko K; Ohira, Tatsuo T; Chikugo, Takaaki T; Satou, Takao T; Matsubayashi, Jun J; Nagao, Toshitaka T; Ikeda, Norihiko N; Tsutani, Yasuhiro Y; Mitsudomi, Tetsuya T; Nishio, Kazuto K
Publication Date: 2023-05-07

Variant appearance in text: EGFR: G719X
PubMed Link: 37174112
Variant Present in the following documents:
  • Main text
  • cancers-15-02648.pdf
View BVdb publication page



A real-world study of Afatinib plus ramucirumab in treatment-naïve, EGFR-mutated, non-small cell lung cancer.

Bmc Cancer
Huang, Chun-Yao CY; Huang, Hui-Li HL; Lan, Chou-Chin CC; Huang, Yi-Chih YC; Wu, Yao-Kuang YK
Publication Date: 2023-05-08

Variant appearance in text: EGFR: G719X
PubMed Link: 37158884
Variant Present in the following documents:
  • Main text
  • 12885_2023_Article_10909.pdf
View BVdb publication page



Infection with human cytomegalovirus, Epstein-Barr virus, and high-risk types 16 and 18 of human papillomavirus in EGFR-mutated lung adenocarcinoma.

Croatian Medical Journal
Harabajsa, Suzana S; Šefčić, Hajdi H; Klasić, Marija M; Milavić, Marija M; Židovec Lepej, Snježana S; Grgić, Ivana I; Zajc Petranović, Matea M; Jakopović, Marko M; Smojver-Ježek, Silvana S; Korać, Petra P
Publication Date: 2023-04-30

Variant appearance in text: EGFR: G719X
PubMed Link: 37131310
Variant Present in the following documents:
  • Main text
  • CroatMedJ_64_0084.pdf
View BVdb publication page



Electromagnetic navigation bronchoscopy transbronchial lung nodule ablation with IllumisiteTM platform corrects CT-to-body divergence with tomosynthesis and improves ablation workflow: a case report.

Ame Case Reports
Chan, Joyce W Y JWY; Chang, Aliss T C ATC; Siu, Ivan C H ICH; Lau, Rainbow W H RWH; Ng, Calvin S H CSH
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 37122960
Variant Present in the following documents:
  • Main text
  • acr-07-22-49.pdf
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Clinical Outcomes of Afatinib Versus Osimertinib in Patients With Non-Small Cell Lung Cancer With Uncommon EGFR Mutations: A Pooled Analysis.

The Oncologist
Wang, Chunsheng C; Zhao, Kewei K; Hu, Shanliang S; Dong, Wei W; Gong, Yan Y; Xie, Conghua C
Publication Date: 2023-04-28

Variant appearance in text: EGFR: G719X
PubMed Link: 37116899
Variant Present in the following documents:
  • Main text
  • oyad111.pdf
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Challenges of EGFR-TKIs in NSCLC and the potential role of herbs and active compounds: From mechanism to clinical practice.

Frontiers In Pharmacology
Song, Xiaotong X; Cao, Luchang L; Ni, Baoyi B; Wang, Jia J; Qin, Xiaoyan X; Sun, Xiaoyue X; Xu, Bowen B; Wang, Xinmiao X; Li, Jie J
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 37089959
Variant Present in the following documents:
  • Main text
  • fphar-14-1090500.pdf
View BVdb publication page



Advances in the Treatment of Rare Epidermal Growth Factor Receptor Mutations in Advanced Nonsmall-Cell Lung Cancer.

Technology In Cancer Research & Treatment
Yu, Limeng L; Wang, Ruilin R; Zhao, Yuhua Y; Wu, Yingxi Y; Wang, Lili L; Chen, Haiyang H; He, Zhen Z; Wang, Qiming Q; Wu, Yufeng Y
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 37078129
Variant Present in the following documents:
  • Main text
  • 10.1177_15330338231168466.pdf
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The Use of Cytotoxic Drugs as First Line Chemotherapy for EGFR (+) Nonsquamous NSCLC: A Network Meta-Analysis.

Disease Markers
Li, Duo D; Li, Meng M; Li, Hong H; Shi, Puyu P; Chen, Mingwei M; Yang, Tian T
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 37077340
Variant Present in the following documents:
  • DM2023-5272125.pdf
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Ultra-rapid Idylla™ EGFR mutation screening followed by next-generation sequencing: An integrated solution to molecular diagnosis of non-small cell lung cancer.

Frontiers In Oncology
Qiu, Tian T; Zhang, Fanshuang F; Zheng, Bo B; Feng, Zitong Z; Li, Weihua W; Zeng, Hua H; Chu, Lixia L; Ying, Jianming J
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 37064089
Variant Present in the following documents:
  • Main text
  • fonc-13-1064487.pdf
View BVdb publication page



Biomarker expression and survival in patients with non-small cell lung cancer receiving adjuvant chemotherapy in Denmark.

Plos One
Dalvi, Tapashi T; Nørgaard, Mette M; Fryzek, Jon P JP; Movva, Naimisha N; Pedersen, Lars L; Pham Hansen, Hanh H; Walker, Jill J; Midha, Anita A; Shire, Norah N; Boothman, Anne-Marie AM; Rigas, James J; Mellemgaard, Anders A; Rasmussen, Torben R TR; Hamilton-Dutoit, Stephen S; Cronin-Fenton, Deirdre D
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 37040387
Variant Present in the following documents:
  • Main text
  • pone.0284037.pdf
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[A Real-world Study on the Expression Characteristics of PD-L1 in Patients 
with Advanced EGFR Positive NSCLC and Its Relationship with the 
Therapeutic Efficacy of EGFR-TKIs].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Chen, Ran R; Gao, Xiang X; Xu, Fudong F; Zhang, Shucai S; Ma, Li L; Hu, Bo B
Publication Date: 2023-03-20

Variant appearance in text: EGFR: G719X
PubMed Link: 37035884
Variant Present in the following documents:
  • zgfazz-26-3-217.pdf
View BVdb publication page



Immune profiles according to EGFR mutant subtypes and correlation with PD-1/PD-L1 inhibitor therapies in lung adenocarcinoma.

Frontiers In Immunology
Koh, Young Wha YW; Park, Bumhee B; Jung, Se Hee SH; Han, Jae-Ho JH; Haam, Seokjin S; Lee, Hyun Woo HW
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 37033978
Variant Present in the following documents:
  • Main text
  • fimmu-14-1137880.pdf
View BVdb publication page



Precision targeted therapy for EGFR mutation-positive NSCLC: Dilemmas and coping strategies.

Thoracic Cancer
Meng, Ying Y; Bai, Rilan R; Cui, Jiuwei J
Publication Date: 2023-04-02

Variant appearance in text: EGFR: G719X
PubMed Link: 37005552
Variant Present in the following documents:
  • Main text
  • TCA-14-1121.pdf
View BVdb publication page



NSCLC in the Era of Targeted and Immunotherapy: What Every Pulmonologist Must Know.

Diagnostics (Basel, Switzerland)
Mitchell, Carley L CL; Zhang, Annie L AL; Bruno, Debora S DS; Almeida, Francisco A FA
Publication Date: 2023-03-15

Variant appearance in text: EGFR: G719X
PubMed Link: 36980426
Variant Present in the following documents:
  • diagnostics-13-01117.pdf
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Randomized Trial of Tepotinib Plus Gefitinib Versus Chemotherapy in EGFR-Mutant NSCLC with EGFR Inhibitor Resistance Due to MET Amplification: INSIGHT Final Analysis.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Liam, Chong Kin CK; Ahmad, Azura Rozila AR; Hsia, Te-Chun TC; Zhou, Jianying J; Kim, Dong-Wan DW; Soo, Ross Andrew RA; Cheng, Ying Y; Lu, Shun S; Shin, Sang Won SW; Yang, James Chi-Hsin JC; Zhang, Yiping Y; Zhao, Jun J; Berghoff, Karin K; Bruns, Rolf R; Johne, Andreas A; Wu, Yi-Long YL
Publication Date: 2023-03-27

Variant appearance in text: EGFR: G719X
PubMed Link: 36971777
Variant Present in the following documents:
  • Main text
  • 1879.pdf
View BVdb publication page



Efficacy of immunotherapy in oncogene-driven non-small-cell lung cancer.

Therapeutic Advances In Medical Oncology
Vokes, Natalie I NI; Pan, Kelsey K; Le, Xiuning X
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 36950275
Variant Present in the following documents:
  • Main text
  • 10.1177_17588359231161409.pdf
View BVdb publication page



Unique profile on the progress free survival and overall survival in patients with advanced non-small cell lung cancer in the Qujing area, Southwest China.

Frontiers In Immunology
Ma, Yuhui Y; Shi, Hutao H; Zhao, Guangqiang G; Liu, Xin X; Cai, Jingjing J; Li, Guangjian G; Chen, Wanlin W; Lei, Yujie Y; Ye, Lianhua L; Fu, Chaojiang C; Zhao, Li L; Zhou, Yongchun Y; Huang, Yunchao Y
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 36926333
Variant Present in the following documents:
  • Main text
  • fimmu-14-1012166.pdf
View BVdb publication page



Monitoring of T790M in plasma ctDNA of advanced EGFR-mutant NSCLC patients on first- or second-generation tyrosine kinase inhibitors.

Bmc Cancer
Huang, Chun-Ta CT; Lin, Chih-An CA; Su, Te-Jen TJ; Yang, Ching-Yao CY; Tsai, Tzu-Hsiu TH; Hsu, Chia-Lin CL; Liao, Wei-Yu WY; Chen, Kuan-Yu KY; Ho, Chao-Chi CC; Yu, Chong-Jen CJ
Publication Date: 2023-03-13

Variant appearance in text: EGFR: G719X
PubMed Link: 36915101
Variant Present in the following documents:
  • Main text
  • 12885_2023_Article_10698.pdf
View BVdb publication page



A single-arm, multicenter, phase II trial of osimertinib in patients with epidermal growth factor receptor exon 18 G719X, exon 20 S768I, or exon 21 L861Q mutations.

Esmo Open
Villaruz, L C LC; Wang, X X; Bertino, E M EM; Gu, L L; Antonia, S J SJ; Burns, T F TF; Clarke, J J; Crawford, J J; Evans, T L TL; Friedland, D M DM; Otterson, G A GA; Ready, N E NE; Wozniak, A J AJ; Stinchcombe, T E TE
Publication Date: 2023-03-09

Variant appearance in text: EGFR: G719X
PubMed Link: 36905787
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Glycomic, Glycoproteomic, and Proteomic Profiling of Philippine Lung Cancer and Peritumoral Tissues: Case Series Study of Patients Stages I-III.

Cancers
Alvarez, Michael Russelle MR; Zhou, Qingwen Q; Tena, Jennyfer J; Barboza, Mariana M; Wong, Maurice M; Xie, Yixuan Y; Lebrilla, Carlito B CB; Cabanatan, Michelle M; Barzaga, Ma Teresa MT; Tan-Liu, Nelia N; Heralde, Francisco M FM; Serrano, Luster L; Nacario, Ruel C RC; Completo, Gladys Cherisse GC
Publication Date: 2023-03-02

Variant appearance in text: EGFR: G719X
PubMed Link: 36900350
Variant Present in the following documents:
  • Main text
  • cancers-15-01559.pdf
View BVdb publication page



Organoid drug screening report for a non-small cell lung cancer patient with EGFR gene mutation negativity: A case report and review of the literature.

Frontiers In Oncology
Pan, Yuetian Y; Cui, Hongshang H; Song, Yongbin Y
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 36874139
Variant Present in the following documents:
  • Main text
  • fonc-13-1109274.pdf
View BVdb publication page



Osimertinib Improves overall survival of EGFR-mutant NSCLC patients with leptomeningeal metastases.

Translational Oncology
Ye, Qiuyue Q; Xu, Yan Y; Zhao, Jing J; Gao, Xiaoxing X; Chen, Minjiang M; Pan, Ruili R; Zhong, Wei W; Wang, Mengzhao M
Publication Date: 2023-03-01

Variant appearance in text: EGFR: G719X
PubMed Link: 36867956
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Nanotechnology - a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer.

Beilstein Journal Of Nanotechnology
Gorachinov, Filip F; Mraiche, Fatima F; Moustafa, Diala Alhaj DA; Hishari, Ola O; Ismail, Yomna Y; Joseph, Jensa J; Crcarevska, Maja Simonoska MS; Dodov, Marija Glavas MG; Geskovski, Nikola N; Goracinova, Katerina K
Publication Date: 2023

Variant appearance in text: EGFR: G719X
PubMed Link: 36865093
Variant Present in the following documents:
  • Beilstein_J_Nanotechnol-14-240.pdf
View BVdb publication page



Real-world clinical analysis in 190 advanced NSCLC patients with uncommon EGFR mutations: A multi-center study.

Cancer Science
Qin, Yi Y; Long, Yaling Y; Tang, Yuan Y; Tian, Yuke Y; Li, Juan J; Duan, Ping P; Luo, Jieyan J; Yu, Min M; Li, Yanying Y; Zhou, Xiaojuan X; Wang, Ke K; Gong, Youling Y; Peng, Feng F; Zhu, Jiang J; Liu, Yongmei Y; Zhou, Lin L; Lu, You Y; Huang, Meijuan M
Publication Date: 2023-02-27

Variant appearance in text: EGFR: G719X
PubMed Link: 36851884
Variant Present in the following documents:
  • Main text
  • CAS-114-2552-s001.pdf
  • CAS-114-2552.pdf
View BVdb publication page



Afatinib in Untreated Stage IIIB/IV Lung Adenocarcinoma with Major Uncommon Epidermal Growth Factor Receptor (EGFR) Mutations (G719X/L861Q/S768I): A Multicenter Observational Study in Taiwan.

Targeted Oncology
Hsu, Ping-Chih PC; Lee, Suey-Haur SH; Chiu, Li-Chung LC; Lee, Chung-Shu CS; Wu, Chiao-En CE; Kuo, Scott Chih-Hsi SC; Ju, Jia-Shiuan JS; Huang, Allen Chung-Cheng AC; Li, Shih-Hong SH; Ko, Ho-Wen HW; Yang, Cheng-Ta CT; Wang, Chin-Chou CC
Publication Date: 2023-02-20

Variant appearance in text: EGFR: G719X
PubMed Link: 36805452
Variant Present in the following documents:
  • 11523_2023_946_MOESM1_ESM.pdf
View BVdb publication page