Clinical and prognostic significance of detecting CEA, EGFR, LunX, c-met and EpCAM mRNA-positive cells in the peripheral blood, tumor-draining blood and bone marrow of non-small cell lung cancer patients.
Translational Lung Cancer Research
Rehulkova, Alona A; Chudacek, Josef J; Prokopova, Andrea A; Vidlarova, Monika M; Stranska, Jana J; Drabek, Jiri J; Potockova, Jana J; Trojanec, Radek R; Vrbkova, Jana J; Skarda, Josef J; Bohanes, Tomas T; Szkorupa, Marek M; Tolmaci, Benjamin B; Klein, Jiri J; Srovnal, Josef J; Hajduch, Marian M
Real world efficacy of osimertinib in second line/beyond in patients with metastatic EGFR+ non-small cell lung cancer and role of paired tumour-plasma T790M testing at tyrosine kinase inhibitor resistance.
Translational Lung Cancer Research
Ma, Jun J; Tan, Sze Huey SH; Yin, Daniel Xing Cheng DXC; Tran, Nguyen Tuan Anh NTA; Tan, Gek San GS; Lai, Gillianne Geet Yi GGY; Ang, Mei-Kim MK; Kanesvaran, Ravindran R; Jain, Amit A; Rajasekaran, Tanujaa T; Tan, Eng-Huat EH; Lim, Tony Kiat Hon TKH; Tan, Daniel Shao-Weng DS; Lim, Darren Wan-Teck DW; Ng, Quan Sing QS; Tan, Wan Ling WL
Comparison between Three Different Techniques for the Detection of EGFR Mutations in Liquid Biopsies of Patients with Advanced Stage Lung Adenocarcinoma.
International Journal Of Molecular Sciences
Casula, Milena M; Pisano, Marina M; Paliogiannis, Panagiotis P; Colombino, Maria M; Sini, Maria Cristina MC; Zinellu, Angelo A; Santeufemia, Davide D; Manca, Antonella A; Casula, Stefania S; Tore, Silvia S; Lobrano, Renato R; Sardinian Lung Cancer Study Group, ; Cossu, Antonio A; Palmieri, Giuseppe G
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Impact of Molecular Testing Using Next-Generation Sequencing in the Clinical Management of Patients with Non-Small Cell Lung Cancer in a Public Healthcare Hospital.
Cancers
Simarro, Javier J; Pérez-Simó, Gema G; Mancheño, Nuria N; Ansotegui, Emilio E; Muñoz-Núñez, Carlos Francisco CF; Gómez-Codina, José J; Juan, Óscar Ó; Palanca, Sarai S
Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non-small Cell Lung Cancer.
Cancer Research Communications
Frank, Malene S MS; Andersen, Christina S A CSA; Ahlborn, Lise B LB; Pallisgaard, Niels N; Bodtger, Uffe U; Gehl, Julie J
Distribution and prognostic impact of EGFR and KRAS mutations according to histological subtype and tumor invasion status in pTis-3N0M0 lung adenocarcinoma.
Bmc Cancer
Ito, Masaoki M; Miyata, Yoshihiro Y; Kushitani, Kei K; Ueda, Daisuke D; Takeshima, Yukio Y; Okada, Morihito M
Case Report: The effective treatment of patients in advanced no-small cell lung cancer patients with EGFR G719X/S768I/L861Q and acquired MET amplification: A case series and literature review.
A single-arm, multicenter, phase II trial of osimertinib in patients with epidermal growth factor receptor exon 18 G719X, exon 20 S768I, or exon 21 L861Q mutations.
Esmo Open
Villaruz, L C LC; Wang, X X; Bertino, E M EM; Gu, L L; Antonia, S J SJ; Burns, T F TF; Clarke, J J; Crawford, J J; Evans, T L TL; Friedland, D M DM; Otterson, G A GA; Ready, N E NE; Wozniak, A J AJ; Stinchcombe, T E TE
Osimertinib in NSCLC With Atypical EGFR-Activating Mutations: A Retrospective Multicenter Study.
Jto Clinical And Research Reports
Ji, Jingran J; Aredo, Jacqueline V JV; Piper-Vallillo, Andrew A; Huppert, Laura L; Rotow, Julia K JK; Husain, Hatim H; Stewart, Susan S; Cobb, Rosemary R; Wakelee, Heather A HA; Blakely, Collin M CM; Wong, Melisa L ML; Gubens, Matthew A MA; Madani, Mohammad H MH; Digumarthy, Subba R SR; McCoach, Caroline C; Piotrowska, Zofia Z; Neal, Joel W JW; Riess, Jonathan W JW
[Initial Treatment of Aumolertinib in Combination with Bevacizumab for Advanced NSCLC with Primary EGFR T790M Mutation: A Report of Three Cases and Literature Review].
Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23
Variant appearance in text: EGFR: 2156G>C; Gly719Ala
Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.
Nature Communications
Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI