Publications:

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Patient-derived cell-based pharmacogenomic assessment to unveil underlying resistance mechanisms and novel therapeutics for advanced lung cancer.

Journal Of Experimental & Clinical Cancer Research : Cr

Yu, Namhee N; Hwang, Mihwa M; Lee, Youngjoo Y; Song, Bo Ram BR; Kang, Eun Hye EH; Sim, Hanna H; Ahn, Beung-Chul BC; Hwang, Kum Hui KH; Kim, Jihyun J; Hong, Sehwa S; Kim, Sunshin S; Park, Charny C; Han, Ji-Youn JY

Publication Date: 2023-01-30

Variant appearance in text: EGFR: I744M

PubMed Link: 36717865

Variant Present in the following documents:

• Main text
• 13046_2023_Article_2606.pdf

View BVdb publication page

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Whole-Exome Sequencing Among Chinese Patients With Hereditary Diffuse Gastric Cancer.

Jama Network Open

Liu, Ze-Xian ZX; Zhang, Xiao-Long XL; Zhao, Qi Q; Chen, Yungchang Y; Sheng, Hui H; He, Cai-Yun CY; Sun, Yu-Ting YT; Lai, Ming-Yu MY; Wu, Min-Qing MQ; Zuo, Zhi-Xiang ZX; Wang, Wei W; Zhou, Zhi-Wei ZW; Wang, Feng-Hua FH; Li, Yu-Hong YH; Xu, Rui-Hua RH; Qiu, Miao-Zhen MZ

Publication Date: 2022-12-01

Variant appearance in text: EGFR: I744M

PubMed Link: 36484990

Variant Present in the following documents:

• jamanetwopen-e2245836-s002.xlsx, sheet 3

View BVdb publication page

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Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics

Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q

Publication Date: 2022-11-04

Variant appearance in text: EGFR: Ile744Met

PubMed Link: 36333792

Variant Present in the following documents:

• 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: EGFR: 2232C>G; I744M

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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Real-World Approach for Molecular Analysis of Acquired EGFR Tyrosine Kinase Inhibitor Resistance Mechanisms in NSCLC.

Jto Clinical And Research Reports

Hondelink, Liesbeth M LM; Jebbink, Merel M; von der Thüsen, Jan H JH; Cohen, Danielle D; Dubbink, Hendrikus J HJ; Paats, Marthe S MS; Dingemans, Anne-Marie C AC; de Langen, Adrianus J AJ; Boelens, Mirjam C MC; Smit, Egbert F EF; Postmus, Pieter E PE; van Wezel, Tom T; Monkhorst, Kim K

Publication Date: 2021-12

Variant appearance in text: EGFR: I744M

PubMed Link: 34849493

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Intertumoural Heterogeneity and Branch Evolution of Synchronous Multiple Primary Lung Adenocarcinomas by Next-Generation Sequencing Analysis.

Frontiers In Oncology

Zhang, Qinleng Q; Jia, Hui H; Wang, Zhendan Z; Hao, Shaoyu S; Huang, Haiyan H; Yang, Airong A; Han, Lu L; Song, Pingping P

Publication Date: 2021

Variant appearance in text: EGFR: 2232C>G; I744M

PubMed Link: 34804960

Variant Present in the following documents:

• Table_1.xls, sheet 1

View BVdb publication page

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High Incidence of C797S Mutation in Patients With Long Treatment History of EGFR Tyrosine Kinase Inhibitors Including Osimertinib.

Jto Clinical And Research Reports

Osoegawa, Atsushi A; Yamaguchi, Masafumi M; Nakamura, Tomomi T; Morinaga, Ryotaro R; Tanaka, Kentaro K; Kashiwabara, Kosuke K; Miura, Takashi T; Suetsugu, Takayuki T; Harada, Taishi T; Asoh, Tatsuma T; Taguchi, Kenichi K; Nabeshima, Kazuki K; Kishimoto, Junji J; Sakai, Kazuko K; Nishio, Kazuto K; Sugio, Kenji K

Publication Date: 2021-07

Variant appearance in text: EGFR: 2232C>G; Ile744Met

PubMed Link: 34590037

Variant Present in the following documents:

• mmc1.xlsx, sheet 1

View BVdb publication page

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NGS-Based ctDNA Profiling After the Resistance of Second-Line Osimertinib for Patient with EGFR-Mutated Pulmonary Adenocarcinoma.

Oncotargets And Therapy

Li, Dan D; Yang, DaFu D; Cui, SaiQiong S; Pan, Evenki E; Yang, Peng P; Dai, ZhaoXia Z

Publication Date: 2021

Variant appearance in text: EGFR: I744M

PubMed Link: 34321891

Variant Present in the following documents:

• Main text
• ott-14-4261.pdf

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2232C>G; I744M

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Does neoadjuvant targeted therapy provide an opportunity for resectable EGFR-mutant lung cancer: a real-world retrospective study.

Journal Of Thoracic Disease

Lv, Chao C; Ma, Yuanyuan Y; Feng, Qin Q; Lu, Fangliang F; Chi, Yongkun Y; Wu, Nan N; Fang, Jian J; Yang, Yue Y

Publication Date: 2020-10

Variant appearance in text: EGFR: I744M

PubMed Link: 33209366

Variant Present in the following documents:

• Main text
• jtd-12-10-5324.pdf

View BVdb publication page

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Oncogenic mutations within the β3-αC loop of EGFR/ERBB2/BRAF/MAP2K1 predict response to therapies.

Molecular Genetics & Genomic Medicine

Zhang, Biao B; Chen, Yongsheng Y; Dai, Pingping P; Yu, Haoda H; Ma, Jianhui J; Chen, Chen C; Zhang, Yan Y; Guan, Yanfang Y; Chen, Rongrong R; Liu, Tao T; Wang, Jiayin J; Yang, Ling L; Yi, Xin X; Xia, Xuefeng X; Ma, Haitao H

Publication Date: 2020-10

Variant appearance in text: EGFR: I744M

PubMed Link: 32757330

Variant Present in the following documents:

• Main text
• MGG3-8-e1395.pdf

View BVdb publication page

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Phase and context shape the function of composite oncogenic mutations.

Nature

Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS

Publication Date: 2020-06

Variant appearance in text: EGFR: I744M

PubMed Link: 32461694

Variant Present in the following documents:

• NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2

View BVdb publication page

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Comprehensive Genomic Profiling of Rare Tumors: Routes to Targeted Therapies.

Frontiers In Oncology

Wang, Shuhang S; Chen, Rongrong R; Tang, Yu Y; Yu, Yue Y; Fang, Yuan Y; Huang, Huiyao H; Wu, Dawei D; Fang, Hong H; Bai, Ying Y; Sun, Chao C; Yu, Anqi A; Fan, Qi Q; Gu, Dejian D; Yi, Xin X; Li, Ning N

Publication Date: 2020

Variant appearance in text: EGFR: 2232C>G; I744M

PubMed Link: 32373528

Variant Present in the following documents:

• Table_6.xlsx, sheet 1

View BVdb publication page

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EGFR T790M detection rate in lung adenocarcinomas at baseline using droplet digital PCR and validation by ultra-deep next generation sequencing.

Translational Lung Cancer Research

Lettig, Lucio L; Sahnane, Nora N; Pepe, Francesco F; Cerutti, Roberta R; Albeni, Chiara C; Franzi, Francesca F; Veronesi, Giovanni G; Ogliari, Francesca F; Pastore, Alessia A; Tuzi, Alessandro A; Pinotti, Graziella G; Bovio, Antonella A; Verusio, Claudio C; Giordano, Monica M; Troncone, Giancarlo G; Sessa, Fausto F; Malapelle, Umberto U; Furlan, Daniela D

Publication Date: 2019-10

Variant appearance in text: EGFR: I744M

PubMed Link: 31737495

Variant Present in the following documents:

• Main text

View BVdb publication page

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[A Review of EGFR-TKIs Therapy of Non-small Cell Lung Cancer
with Uncommon EGFR Mutations].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Du, Wenxing W; Wo, Yang Y; Lu, Tong T; Wang, Yuanyong Y; Jiao, Wenjie W

Publication Date: 2019-09-20

Variant appearance in text: EGFR: I744M

PubMed Link: 31526464

Variant Present in the following documents:

• Main text
• zgfazz-22-9-590.pdf

View BVdb publication page

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First-generation EGFR tyrosine kinase inhibitor therapy in 106 patients with compound EGFR-mutated lung cancer: a single institution's clinical practice experience.

Cancer Communications (London, England)

Yu, Xiangyang X; Zhang, Xuewen X; Zhang, Zichen Z; Lin, Yongbin Y; Wen, Yingsheng Y; Chen, Yongqiang Y; Wang, Weidong W; Zhang, Lanjun L

Publication Date: 2018-07-28

Variant appearance in text: EGFR: I744M

PubMed Link: 30055651

Variant Present in the following documents:

• Main text
• 40880_2018_Article_321.pdf

View BVdb publication page

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Brain metastasis in non-small cell lung cancer (NSCLC) patients with uncommon EGFR mutations: a report of seven cases and literature review.

Cancer Biology & Medicine

Er, Puchun P; Zhang, Tian T; Wang, Jing J; Pang, Qingsong Q; Wang, Ping P

Publication Date: 2017-11

Variant appearance in text: EGFR: I744M

PubMed Link: 29372109

Variant Present in the following documents:

• cbm-14-4-418.pdf

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Clinical mutational profiling of 1006 lung cancers by next generation sequencing.

Oncotarget

Illei, Peter B PB; Belchis, Deborah D; Tseng, Li-Hui LH; Nguyen, Doreen D; De Marchi, Federico F; Haley, Lisa L; Riel, Stacy S; Beierl, Katie K; Zheng, Gang G; Brahmer, Julie R JR; Askin, Frederic B FB; Gocke, Christopher D CD; Eshleman, James R JR; Forde, Patrick M PM; Lin, Ming-Tseh MT

Publication Date: 2017-11-14

Variant appearance in text: EGFR: I744M

PubMed Link: 29228562

Variant Present in the following documents:

• oncotarget-08-96684.pdf

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Cancer gene profiling in non-small cell lung cancers reveals activating mutations in JAK2 and JAK3 with therapeutic implications.

Genome Medicine

Li, Shuyu D SD; Ma, Meng M; Li, Hui H; Waluszko, Aneta A; Sidorenko, Tatyana T; Schadt, Eric E EE; Zhang, David Y DY; Chen, Rong R; Ye, Fei F

Publication Date: 2017-10-30

Variant appearance in text: EGFR: 2232C>G; Ile744Met

PubMed Link: 29082853

Variant Present in the following documents:

• 13073_2017_478_MOESM1_ESM.xlsx, sheet 2

View BVdb publication page

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Natural Products as Chemopreventive Agents by Potential Inhibition of the Kinase Domain in ErbB Receptors.

Molecules (Basel, Switzerland)

Olivero-Acosta, Maria M; Maldonado-Rojas, Wilson W; Olivero-Verbel, Jesus J

Publication Date: 2017-02-17

Variant appearance in text: EGFR: I744M

PubMed Link: 28218686

Variant Present in the following documents:

• Main text

View BVdb publication page

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Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment.

British Journal Of Cancer

Kuiper, J L JL; Hashemi, S M S SM; Thunnissen, E E; Snijders, P J F PJ; Grünberg, K K; Bloemena, E E; Sie, D D; Postmus, P E PE; Heideman, D A M DA; Smit, E F EF

Publication Date: 2016-12-06

Variant appearance in text: EGFR: I744M

PubMed Link: 27875527

Variant Present in the following documents:

• Main text
• bjc2016372a.pdf

View BVdb publication page

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Comprehensive Molecular Analysis of NSCLC; Clinicopathological Associations.

Plos One

Chatziandreou, Ilenia I; Tsioli, Panagiota P; Sakellariou, Stratigoula S; Mourkioti, Ioanna I; Giannopoulou, Ioanna I; Levidou, Georgia G; Korkolopoulou, Penelope P; Patsouris, Efstratios E; Saetta, Angelica A AA

Publication Date: 2015

Variant appearance in text: EGFR: Ile744Met

PubMed Link: 26208325

Variant Present in the following documents:

• Main text
• pone.0133859.pdf

View BVdb publication page

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EGFR mutation testing in patients with advanced non-small cell lung cancer: a comprehensive evaluation of real-world practice in an East Asian tertiary hospital.

Plos One

Choi, Yoon-La YL; Sun, Jong-Mu JM; Cho, Juhee J; Rampal, Sanjay S; Han, Joungho J; Parasuraman, Bhash B; Guallar, Eliseo E; Lee, Genehee G; Lee, Jeeyun J; Shim, Young Mog YM

Publication Date: 2013

Variant appearance in text: EGFR: I744M

PubMed Link: 23468851

Variant Present in the following documents:

• Main text
• pone.0056011.pdf

View BVdb publication page

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DNA-Mutation Inventory to Refine and Enhance Cancer Treatment (DIRECT): a catalog of clinically relevant cancer mutations to enable genome-directed anticancer therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Yeh, Paul P; Chen, Heidi H; Andrews, Jenny J; Naser, Riyad R; Pao, William W; Horn, Leora L

Publication Date: 2013-04-01

Variant appearance in text: EGFR: I744M

PubMed Link: 23344264

Variant Present in the following documents:

• Main text

View BVdb publication page

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