Publications:

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Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer

Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J

Publication Date: 2023-03-31

Variant appearance in text: EGFR: Leu747_Glu749del

PubMed Link: 37004022

Variant Present in the following documents:

• Main text
• 12885_2023_Article_10674.pdf

View BVdb publication page

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Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non-small Cell Lung Cancer.

Cancer Research Communications

Frank, Malene S MS; Andersen, Christina S A CSA; Ahlborn, Lise B LB; Pallisgaard, Niels N; Bodtger, Uffe U; Gehl, Julie J

Publication Date: 2022-10

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 36969747

Variant Present in the following documents:

• crc-22-0258-s08.xlsx, sheet 1

View BVdb publication page

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: EGFR: 2239_2247del; Leu747_Glu749del

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6

View BVdb publication page

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Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer.

Nature Communications

Chmielecki, Juliann J; Gray, Jhanelle E JE; Cheng, Ying Y; Ohe, Yuichiro Y; Imamura, Fumio F; Cho, Byoung Chul BC; Lin, Meng-Chih MC; Majem, Margarita M; Shah, Riyaz R; Rukazenkov, Yuri Y; Todd, Alexander A; Markovets, Aleksandra A; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Ramalingam, Suresh S SS

Publication Date: 2023-02-27

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA

PubMed Link: 36849494

Variant Present in the following documents:

• 41467_2023_35961_MOESM3_ESM.xlsx, sheet 2

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: EGFR: 2239_2247del; Leu747_Glu749del

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Clinical outcome of Brazilian patients with non-small cell lung cancer in early stage harboring rare mutations in epidermal growth factor receptor.

Brazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas

Machado-Rugolo, J J; Baldavira, C M CM; Prieto, T G TG; Olivieri, E H R EHR; Fabro, A T AT; Rainho, C A CA; Castelli, E C EC; Ribolla, P E M PEM; Ab'Saber, A M AM; Takagaki, T T; Nagai, M A MA; Capelozzi, V L VL

Publication Date: 2023

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; E746_R748del

PubMed Link: 36629526

Variant Present in the following documents:

• Main text
• 1414-431X-bjmbr-55-e12409.pdf

View BVdb publication page

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Case report: olaparib use in metastatic lung adenocarcinoma with BRCA2 pathogenic variant.

Cold Spring Harbor Molecular Case Studies

Soon Jian Hao, Jonathan J; Hoai, Chan Sock CS; Weng, Daniel Tan Shao DTS; Ngeow, Joanne J; Chiang, Jianbang J

Publication Date: 2022-12

Variant appearance in text: EGFR: 2239_2247del; L747_E749del

PubMed Link: 36577523

Variant Present in the following documents:

• supp_mcs.a006223_Supplemental_Material.pdf

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 2
• Table_2.xlsx, sheet 3

View BVdb publication page

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Liquid biopsy using ascitic fluid and pleural effusion supernatants for genomic profiling in gastrointestinal and lung cancers.

Bmc Cancer

Wu, Huita H; Ji, Haonan H; Yang, Wenhui W; Zhang, Min M; Guo, Yifang Y; Li, Bangkai B; Wang, Jiayin J; Chen, Rongrong R; Chen, Yuan Y; Wang, Xin X

Publication Date: 2022-09-27

Variant appearance in text: EGFR: L747_E749del

PubMed Link: 36167530

Variant Present in the following documents:

• 12885_2022_9922_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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New methodology of TMB assessment from tissue and liquid biopsy in NSCLC.

Plos One

Křížová, Ľudmila Ľ; Šafaříková, Markéta M; Kalousová, Marta M; Pfeiferová, Lucie L; Kuběna, Aleš Antonín AA; Vočka, Michal M; Ulrych, Jan J; Franková, Věra V; Petruželka, Luboš L; Zima, Tomáš T; Feltl, David D

Publication Date: 2022

Variant appearance in text: EGFR: 2239_2247del; Leu747_Glu749del

PubMed Link: 36155654

Variant Present in the following documents:

• pone.0275121.s002.xlsx, sheet 14

View BVdb publication page

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Landscape of EGFR mutations in lung adenocarcinoma: a single institute experience with comparison of PANAMutyper testing and targeted next-generation sequencing.

Journal Of Pathology And Translational Medicine

Lee, Jeonghyo J; Han, Yeon Bi YB; Kwon, Hyun Jung HJ; Lee, Song Kook SK; Kim, Hyojin H; Chung, Jin-Haeng JH

Publication Date: 2022-09

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 36128861

Variant Present in the following documents:

• jptm-2022-06-11-suppl1.pdf

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Allele-specific activation, enzyme kinetics, and inhibitor sensitivities of EGFR exon 19 deletion mutations in lung cancer.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Brown, Benjamin P BP; Zhang, Yun-Kai YK; Kim, Soyeon S; Finneran, Patrick P; Yan, Yingjun Y; Du, Zhenfang Z; Kim, Jiyoon J; Hartzler, Abigail Leigh AL; LeNoue-Newton, Michele L ML; Smith, Adam W AW; Meiler, Jens J; Lovly, Christine M CM

Publication Date: 2022-07-26

Variant appearance in text: EGFR: L747_E749del

PubMed Link: 35867821

Variant Present in the following documents:

• pnas.2206588119.sapp.pdf

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW

Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; Leu747_Glu749del

PubMed Link: 35606799

Variant Present in the following documents:

• 41021_2022_248_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer.

Frontiers In Oncology

Cai, Jun J; Jiang, Huihui H; Li, Shuqing S; Yan, Xiaoxia X; Wang, Meng M; Li, Na N; Zhu, Cuimin C; Dong, Hui H; Wang, Dongjuan D; Xu, Yue Y; Xie, Hui H; Wu, Shouxin S; Lou, Jingwei J; Zhao, Jiangman J; Li, Qingshan Q

Publication Date: 2021

Variant appearance in text: EGFR: 2236_2244del

PubMed Link: 35273907

Variant Present in the following documents:

• Table_8.xlsx, sheet 1

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine

Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R

Publication Date: 2022-05

Variant appearance in text: EGFR: 2236_2244delGAATTAAGA; Glu746_Arg748del

PubMed Link: 35244186

Variant Present in the following documents:

• Supplementary_Data2.xlsx, sheet 1
• Supplementary_Data3.xlsx, sheet 1

View BVdb publication page

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Identifying Actionable Variants Using Capture-Based Targeted Sequencing in 563 Patients With Non-Small Cell Lung Carcinoma.

Frontiers In Oncology

Jiang, Haiping H; Wang, Yinan Y; Xu, Hanlin H; Lei, Wei W; Yu, Xiaoyun X; Tian, Haiying H; Meng, Cong C; Wang, Xueying X; Zhao, Zicheng Z; Jin, Xiangfeng X

Publication Date: 2021

Variant appearance in text: EGFR: 2236_2244del; L747_E749del

PubMed Link: 35186718

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: EGFR: 2239_2247del; Leu747_Glu749del

PubMed Link: 35031014

Variant Present in the following documents:

• Main text
• 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1
• 12864_2021_Article_8289.pdf

View BVdb publication page

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Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: EGFR: 2239_2247del; Leu747_Glu749del

PubMed Link: 35031014

Variant Present in the following documents:

• Main text
• 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1
• 12864_2021_Article_8289.pdf

View BVdb publication page

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Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 34887858

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

View BVdb publication page

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Evaluation of the Mutation Profile via Next-Generation Sequencing in a Turkish Population With Non-small Cell Lung Cancer.

Balkan Medical Journal

Kahraman Çetin, Nesibe N; Erdoğdu, İbrahim Halil İH; Bozkurt, Emin E; Meteoğlu, İbrahim İ

Publication Date: 2021-11

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 34860166

Variant Present in the following documents:

• bmj-38-6-382.pdf

View BVdb publication page

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Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer.

Translational Oncology

Metzenmacher, Martin M; Hegedüs, Balazs B; Forster, Jan J; Schramm, Alexander A; Horn, Peter A PA; Klein, Christoph A CA; Bielefeld, Nicola N; Ploenes, Till T; Aigner, Clemens C; Theegarten, Dirk D; Schildhaus, Hans-Ulrich HU; Siveke, Jens T JT; Schuler, Martin M; Lueong, Smiths S SS

Publication Date: 2022-01

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; Leu747_Glu749del

PubMed Link: 34800919

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

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Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer.

Translational Oncology

Metzenmacher, Martin M; Hegedüs, Balazs B; Forster, Jan J; Schramm, Alexander A; Horn, Peter A PA; Klein, Christoph A CA; Bielefeld, Nicola N; Ploenes, Till T; Aigner, Clemens C; Theegarten, Dirk D; Schildhaus, Hans-Ulrich HU; Siveke, Jens T JT; Schuler, Martin M; Lueong, Smiths S SS

Publication Date: 2021-11-17

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; Leu747_Glu749del

PubMed Link: 34800919

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

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Dynamic recurrence risk and adjuvant chemotherapy benefit prediction by ctDNA in resected NSCLC.

Nature Communications

Qiu, Bin B; Guo, Wei W; Zhang, Fan F; Lv, Fang F; Ji, Ying Y; Peng, Yue Y; Chen, Xiaoxi X; Bao, Hua H; Xu, Yang Y; Shao, Yang Y; Tan, Fengwei F; Xue, Qi Q; Gao, Shugeng S; He, Jie J

Publication Date: 2021-11-19

Variant appearance in text: EGFR: 2239_2247del; L747_E749del

PubMed Link: 34799585

Variant Present in the following documents:

• 41467_2021_27022_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Dynamic recurrence risk and adjuvant chemotherapy benefit prediction by ctDNA in resected NSCLC.

Nature Communications

Qiu, Bin B; Guo, Wei W; Zhang, Fan F; Lv, Fang F; Ji, Ying Y; Peng, Yue Y; Chen, Xiaoxi X; Bao, Hua H; Xu, Yang Y; Shao, Yang Y; Tan, Fengwei F; Xue, Qi Q; Gao, Shugeng S; He, Jie J

Publication Date: 2021-11-19

Variant appearance in text: EGFR: 2239_2247del; L747_E749del

PubMed Link: 34799585

Variant Present in the following documents:

• 41467_2021_27022_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Evaluation of the MGISEQ-2000 Sequencing Platform for Illumina Target Capture Sequencing Libraries.

Frontiers In Genetics

Lang, Jidong J; Zhu, Rongrong R; Sun, Xue X; Zhu, Siyu S; Li, Tianbao T; Shi, Xiaoli X; Sun, Yanqi Y; Yang, Zhou Z; Wang, Weiwei W; Bing, Pingping P; He, Binsheng B; Tian, Geng G

Publication Date: 2021

Variant appearance in text: EGFR: 2237_2245del

PubMed Link: 34777467

Variant Present in the following documents:

• DataSheet1.xlsx, sheet 4

View BVdb publication page

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Targeted Sequencing Revealed Distinct Mutational Profiles of Ocular and Extraocular Sebaceous Carcinomas.

Cancers

Na, Hee Young HY; Park, Jeong Hwan JH; Shin, Sun Ah SA; Lee, Sejoon S; Lee, Heonyi H; Chae, Heejoon H; Choung, HoKyung H; Kim, Namju N; Chung, Jin-Haeng JH; Kim, Ji Eun JE

Publication Date: 2021-09-26

Variant appearance in text: EGFR: L747_E749del

PubMed Link: 34638295

Variant Present in the following documents:

• Main text
• cancers-13-04810.pdf

View BVdb publication page

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High Incidence of C797S Mutation in Patients With Long Treatment History of EGFR Tyrosine Kinase Inhibitors Including Osimertinib.

Jto Clinical And Research Reports

Osoegawa, Atsushi A; Yamaguchi, Masafumi M; Nakamura, Tomomi T; Morinaga, Ryotaro R; Tanaka, Kentaro K; Kashiwabara, Kosuke K; Miura, Takashi T; Suetsugu, Takayuki T; Harada, Taishi T; Asoh, Tatsuma T; Taguchi, Kenichi K; Nabeshima, Kazuki K; Kishimoto, Junji J; Sakai, Kazuko K; Nishio, Kazuto K; Sugio, Kenji K

Publication Date: 2021-07

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; Leu747_Glu749del

PubMed Link: 34590037

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

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RBM10 Deficiency Is Associated With Increased Immune Activity in Lung Adenocarcinoma.

Frontiers In Oncology

Liu, Bing B; Wang, Yaqi Y; Wang, Han H; Li, Zhongwu Z; Yang, Lujing L; Yan, Shi S; Yang, Xin X; Ma, Yuanyuan Y; Gao, Xuan X; Guan, Yanfang Y; Yi, Xin X; Xia, Xuefeng X; Li, Jingjing J; Wu, Nan N

Publication Date: 2021

Variant appearance in text: EGFR: L747_E749del

PubMed Link: 34367963

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

View BVdb publication page

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Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma With Micropapillary Component.

Frontiers In Oncology

Zhang, Shirong S; Xu, Yang Y; Zhao, Pan P; Bao, Hua H; Wang, Xiyong X; Liu, Rui R; Xu, Rujun R; Xiang, Jingjing J; Jiang, Hong H; Yan, Junrong J; Wu, Xue X; Shao, Yang Y; Liang, Jiafeng J; Wu, Qiong Q; Zhang, Zhihao Z; Lu, Shun S; Ma, Shenglin S

Publication Date: 2021

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA

PubMed Link: 34221970

Variant Present in the following documents:

• Table_5.xlsx, sheet 1

View BVdb publication page

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Liquid biopsy as an option for predictive testing and prognosis in patients with lung cancer.

Molecular Medicine (Cambridge, Mass.)

Qvick, Alvida A; Stenmark, Bianca B; Carlsson, Jessica J; Isaksson, Johan J; Karlsson, Christina C; Helenius, Gisela G

Publication Date: 2021-07-03

Variant appearance in text: EGFR: Leu747_Glu749del

PubMed Link: 34217228

Variant Present in the following documents:

• Main text

View BVdb publication page

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Dynamic Evaluation of Circulating miRNA Profile in EGFR-Mutated NSCLC Patients Treated with EGFR-TKIs.

Cells

Leonetti, Alessandro A; Capula, Mjriam M; Minari, Roberta R; Mazzaschi, Giulia G; Gregori, Alessandro A; El Hassouni, Btissame B; Papini, Filippo F; Bordi, Paola P; Verzè, Michela M; Avan, Amir A; Tiseo, Marcello M; Giovannetti, Elisa E

Publication Date: 2021-06-16

Variant appearance in text: EGFR: 2239_2247del

PubMed Link: 34208765

Variant Present in the following documents:

• Main text
• cells-10-01520.pdf

View BVdb publication page

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Sensitivity, specificity, and accuracy of a liquid biopsy approach utilizing molecular amplification pools.

Scientific Reports

Garcia, Jessica J; Kamps-Hughes, Nick N; Geiguer, Florence F; Couraud, Sébastien S; Sarver, Brice B; Payen, Léa L; Ionescu-Zanetti, Cristian C

Publication Date: 2021-05-24

Variant appearance in text: EGFR: 2236_2244del

PubMed Link: 34031447

Variant Present in the following documents:

• 41598_2021_89592_MOESM1_ESM.xlsx, sheet 3

View BVdb publication page

---

Plasma pre-treatment T790M relative allelic frequency in patients with advanced EGFR-mutated non-small cell lung cancer predicts treatment response to subsequent-line osimertinib.

Translational Lung Cancer Research

Ding, Pei N PN; Roberts, Tara L TL; Chua, Wei W; Becker, Therese M TM; Caixeiro, Nicole N; de Souza, Paul P; Gao, Bo B; Lee, Chee K CK; Itchins, Malinda M; Westman, Helen H; Clarke, Stephen S; Blinman, Prunella P; Kao, Steven S; John, Tom T; Leal, Jose L JL; Bray, Victoria J VJ

Publication Date: 2021-04

Variant appearance in text: EGFR: 2239_2247del

PubMed Link: 34012779

Variant Present in the following documents:

• tlcr-10-04-1623-prf.pdf

View BVdb publication page

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Targeting FGFR in non-small cell lung cancer: implications from the landscape of clinically actionable aberrations of FGFR kinases.

Cancer Biology & Medicine

Zhou, Zhen Z; Liu, Zichuan Z; Ou, Qiuxiang Q; Wu, Xue X; Wang, Xiaonan X; Shao, Yang Y; Liu, Hongyan H; Yang, Yu Y

Publication Date: 2021-03-12

Variant appearance in text: EGFR: L747_E749del

PubMed Link: 33710807

Variant Present in the following documents:

• Main text
• cbm-18-490.pdf

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: EGFR: 2239_2247del; L747_E749del

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Routine Molecular Screening of Patients with Advanced Non-SmallCell Lung Cancer in Circulating Cell-Free DNA at Diagnosis and During Progression Using OncoBEAMTM EGFR V2 and NGS Technologies.

Molecular Diagnosis & Therapy

Garcia, Jessica J; Gauthier, Arnaud A; Lescuyer, Gaëlle G; Barthelemy, David D; Geiguer, Florence F; Balandier, Julie J; Edelstein, Daniel L DL; Jones, Frederick S FS; Holtrup, Frank F; Duruisseau, Mickael M; Grolleau, Emmanuel E; Rodriguez-Lafrasse, Claire C; Merle, Patrick P; Couraud, Sébastien S; Payen, Léa L

Publication Date: 2021-03

Variant appearance in text: EGFR: 2239_2247del; L747_E749del

PubMed Link: 33660188

Variant Present in the following documents:

• 40291_2021_515_MOESM1_ESM.pdf

View BVdb publication page

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Mutation profile of non-small cell lung cancer revealed by next generation sequencing.

Respiratory Research

Chang, Ya-Sian YS; Tu, Siang-Jyun SJ; Chen, Yu-Chia YC; Liu, Ting-Yuan TY; Lee, Ya-Ting YT; Yen, Ju-Chen JC; Fang, Hsin-Yuan HY; Chang, Jan-Gowth JG

Publication Date: 2021-01-06

Variant appearance in text: EGFR: 2236_2244del

PubMed Link: 33407425

Variant Present in the following documents:

• 12931_2020_1608_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1
• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

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Predicting osimertinib-treatment outcomes through EGFR mutant-fraction monitoring in the circulating tumor DNA of EGFR T790M-positive patients with non-small cell lung cancer (WJOG8815L).

Molecular Oncology

Sakai, Kazuko K; Takahama, Takayuki T; Shimokawa, Mototsugu M; Azuma, Koichi K; Takeda, Masayuki M; Kato, Terufumi T; Daga, Haruko H; Okamoto, Isamu I; Akamatsu, Hiroaki H; Teraoka, Shunsuke S; Ono, Akira A; Ohira, Tatsuo T; Yokoyama, Toshihide T; Yamamoto, Nobuyuki N; Nakagawa, Kazuhiko K; Nishio, Kazuto K

Publication Date: 2021-01

Variant appearance in text: EGFR: E746_R748del

PubMed Link: 33131198

Variant Present in the following documents:

• MOL2-15-126-s007.xlsx, sheet 1

View BVdb publication page

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Mass Spectrometry as a Highly Sensitive Method for Specific Circulating Tumor DNA Analysis in NSCLC: A Comparison Study.

Cancers

Lamy, Pierre-Jean PJ; van der Leest, Paul P; Lozano, Nicolas N; Becht, Catherine C; Duboeuf, Frédérique F; Groen, Harry J M HJM; Hilgers, Werner W; Pourel, Nicolas N; Rifaela, Naomi N; Schuuring, Ed E; Alix-Panabières, Catherine C

Publication Date: 2020-10-16

Variant appearance in text: EGFR: 2239_2247del; L747_E749del

PubMed Link: 33081150

Variant Present in the following documents:

• cancers-12-03002-s001.pdf

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Construction of a reference material panel for detecting KRAS/NRAS/EGFR/BRAF/MET mutations in plasma ctDNA.

Journal Of Clinical Pathology

Xu, Jun J; Qu, Shoufang S; Sun, Nan N; Zhang, Wenxin W; Zhang, Juanli J; Song, Qingtao Q; Lin, Mufei M; Gao, Wei W; Zheng, Qiaosong Q; Han, Mipeng M; Na, Chenglong C; Xu, Ren R; Chang, Xiaoyan X; Yang, Xuexi X; Huang, Jie J

Publication Date: 2021-05

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 32817175

Variant Present in the following documents:

• Main text

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Oncogenic mutations within the β3-αC loop of EGFR/ERBB2/BRAF/MAP2K1 predict response to therapies.

Molecular Genetics & Genomic Medicine

Zhang, Biao B; Chen, Yongsheng Y; Dai, Pingping P; Yu, Haoda H; Ma, Jianhui J; Chen, Chen C; Zhang, Yan Y; Guan, Yanfang Y; Chen, Rongrong R; Liu, Tao T; Wang, Jiayin J; Yang, Ling L; Yi, Xin X; Xia, Xuefeng X; Ma, Haitao H

Publication Date: 2020-10

Variant appearance in text: EGFR: L747_E749del

PubMed Link: 32757330

Variant Present in the following documents:

• Main text
• MGG3-8-e1395.pdf

View BVdb publication page

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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Mutation and drug-specific intracellular accumulation of EGFR predict clinical responses to tyrosine kinase inhibitors.

Ebiomedicine

de Wit, Maurice M; Gao, Ya Y; Mercieca, Darlene D; de Heer, Iris I; Valkenburg, Bart B; van Royen, Martin E ME; Aerts, Joachim J; Sillevis Smitt, Peter P; French, Pim P

Publication Date: 2020-06

Variant appearance in text: EGFR: L747_E749del

PubMed Link: 32512509

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Electric Field-Induced Release and Measurement (EFIRM): Characterization and Technical Validation of a Novel Liquid Biopsy Platform in Plasma and Saliva.

The Journal Of Molecular Diagnostics : Jmd

Tu, Michael M; Cheng, Jordan J; Chen, Yi-Lin YL; Jea, Wen-Chien WC; Chen, Wan-Li WL; Chen, Chien-Jung CJ; Ho, Chung-Liang CL; Huang, Wei-Lun WL; Lin, Chien-Chung CC; Su, Wu-Chou WC; Ye, Qianlin Q; Deignan, Josh J; Grody, Wayne W; Li, Feng F; Chia, David D; Wei, Fang F; Liao, Wei W; Wong, David T W DTW; Strom, Charles M CM

Publication Date: 2020-08

Variant appearance in text: EGFR: L747_E749del

PubMed Link: 32497715

Variant Present in the following documents:

• Main text

View BVdb publication page

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Molecular Diagnostic of Solid Tumor Using a Next Generation Sequencing Custom-Designed Multi-Gene Panel.

Diagnostics (Basel, Switzerland)

de Biase, Dario D; Acquaviva, Giorgia G; Visani, Michela M; Sanza, Viviana V; Argento, Chiara M CM; De Leo, Antonio A; Maloberti, Thais T; Pession, Annalisa A; Tallini, Giovanni G

Publication Date: 2020-04-23

Variant appearance in text: EGFR: 2239_2247del; L747_E749del

PubMed Link: 32340363

Variant Present in the following documents:

• diagnostics-10-00250-s001.pdf

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Targeted sequencing analysis of cell-free DNA from metastatic non-small-cell lung cancer patients: clinical and biological implications.

Translational Lung Cancer Research

Pasquale, Raffaella R; Forgione, Laura L; Roma, Cristin C; Fenizia, Francesca F; Bergantino, Francesca F; Rachiglio, Anna M AM; De Luca, Antonella A; Gallo, Marianna M; Maiello, Monica R MR; Palumbo, Giuliano G; Morabito, Alessandro A; Azzaro, Rosa R; Normanno, Nicola N

Publication Date: 2020-02

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA

PubMed Link: 32206554

Variant Present in the following documents:

• Main text

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Rapid EGFR mutation testing in lung cancer tissue samples using a fully automated system and single-use cartridge.

Practical Laboratory Medicine

Al-Turkmani, M Rabie MR; Suriawinata, Michael A MA; Deharvengt, Sophie J SJ; Green, Donald C DC; Black, Candice C CC; Shirai, Keisuke K; Dragnev, Konstantin H KH; Tsongalis, Gregory J GJ

Publication Date: 2020-05

Variant appearance in text: EGFR: 2239_2247del

PubMed Link: 32181314

Variant Present in the following documents:

• Main text
• main.pdf

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Spectrum of EGFR aberrations and potential clinical implications: insights from integrative pan-cancer analysis.

Cancer Communications (London, England)

Liu, Haijing H; Zhang, Bo B; Sun, Zhifu Z

Publication Date: 2020-01

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA

PubMed Link: 32067422

Variant Present in the following documents:

• CAC2-40-43-s001.xlsx, sheet 1

View BVdb publication page

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Pan-cancer whole-genome analyses of metastatic solid tumours.

Nature

Priestley, Peter P; Baber, Jonathan J; Lolkema, Martijn P MP; Steeghs, Neeltje N; de Bruijn, Ewart E; Shale, Charles C; Duyvesteyn, Korneel K; Haidari, Susan S; van Hoeck, Arne A; Onstenk, Wendy W; Roepman, Paul P; Voda, Mircea M; Bloemendal, Haiko J HJ; Tjan-Heijnen, Vivianne C G VCG; van Herpen, Carla M L CML; Labots, Mariette M; Witteveen, Petronella O PO; Smit, Egbert F EF; Sleijfer, Stefan S; Voest, Emile E EE; Cuppen, Edwin E

Publication Date: 2019-11

Variant appearance in text: EGFR: Glu746_Arg748del

PubMed Link: 31645765

Variant Present in the following documents:

• 41586_2019_1689_MOESM10_ESM.xlsx, sheet 1
• 41586_2019_1689_MOESM14_ESM.xlsx, sheet 1

View BVdb publication page

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Development, Implementation and Assessment of Molecular Diagnostics by Next Generation Sequencing in Personalized Treatment of Cancer: Experience of a Public Reference Healthcare Hospital.

Cancers

Simarro, Javier J; Murria, Rosa R; Pérez-Simó, Gema G; Llop, Marta M; Mancheño, Nuria N; Ramos, David D; Juan, Inmaculada de I; Barragán, Eva E; Laiz, Begoña B; Cases, Enrique E; Ansótegui, Emilio E; Gómez-Codina, José J; Aparicio, Jorge J; Salvador, Carmen C; Juan, Óscar Ó; Palanca, Sarai S

Publication Date: 2019-08-16

Variant appearance in text: EGFR: Glu746_Arg748del

PubMed Link: 31426418

Variant Present in the following documents:

• cancers-11-01196-s001.pdf

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Exosome-based detection of activating and resistance EGFR mutations from plasma of non-small cell lung cancer patients.

Oncotarget

Castellanos-Rizaldos, Elena E; Zhang, Xuan X; Tadigotla, Vasisht R VR; Grimm, Dominik G DG; Karlovich, Chris C; Raez, Luis E LE; Skog, Johan K JK

Publication Date: 2019-04-23

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA

PubMed Link: 31080561

Variant Present in the following documents:

• Main text
• oncotarget-10-2911.pdf

View BVdb publication page

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The correlations of tumor mutational burden among single-region tissue, multi-region tissues and blood in non-small cell lung cancer.

Journal For Immunotherapy Of Cancer

Zhang, Yaxiong Y; Chang, Lianpeng L; Yang, Yunpeng Y; Fang, Wenfeng W; Guan, Yanfang Y; Wu, Aiwei A; Hong, Shaodong S; Zhou, Huaqiang H; Chen, Gang G; Chen, Xi X; Zhao, Shen S; Zheng, Qiufan Q; Pan, Hui H; Zhang, Lanjun L; Long, Hao H; Yang, Haoxian H; Wang, Xin X; Wen, Zhesheng Z; Wang, Junye J; Yang, Hong H; Xia, Xuefeng X; Zhao, Yuanyuan Y; Hou, Xue X; Ma, Yuxiang Y; Zhou, Ting T; Zhang, Zhonghan Z; Zhan, Jianhua J; Huang, Yan Y; Zhao, Hongyun H; Zhou, Ningning N; Yi, Xin X; Zhang, Li L

Publication Date: 2019-04-03

Variant appearance in text: EGFR: L747_E749del

PubMed Link: 30944026

Variant Present in the following documents:

• 40425_2019_581_MOESM3_ESM.pdf

View BVdb publication page

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Integrated Somatic and Germline Whole-Exome Sequencing Analysis in Women with Lung Cancer after a Previous Breast Cancer.

Cancers

Coco, Simona S; Bonfiglio, Silvia S; Cittaro, Davide D; Vanni, Irene I; Mora, Marco M; Genova, Carlo C; Dal Bello, Maria Giovanna MG; Boccardo, Simona S; Alama, Angela A; Rijavec, Erika E; Sini, Claudio C; Rossella, Valeria V; Barletta, Giulia G; Biello, Federica F; Truini, Anna A; Bruzzo, Cristina C; Gallo, Maurizio M; Lazarevic, Dejan D; Ballestrero, Alberto A; Grossi, Francesco F

Publication Date: 2019-03-28

Variant appearance in text: EGFR: Glu746_Arg748del

PubMed Link: 30925779

Variant Present in the following documents:

• Main text

View BVdb publication page

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EGFR C797S, EGFR T790M and EGFR sensitizing mutations in non-small cell lung cancer revealed by six-color crystal digital PCR.

Oncotarget

Madic, Jordan J; Jovelet, Cécile C; Lopez, Julien J; André, Barbara B; Fatien, Jean J; Miran, Isabelle I; Honoré, Aurélie A; Mezquita, Laura L; Besse, Benjamin B; Lacroix, Ludovic L; Droniou, Magali M

Publication Date: 2018-12-21

Variant appearance in text: EGFR: 2239_2247del

PubMed Link: 30647840

Variant Present in the following documents:

• Main text
• oncotarget-09-37393.pdf

View BVdb publication page

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Intratumor heterogeneity comparison among different subtypes of non-small-cell lung cancer through multi-region tissue and matched ctDNA sequencing.

Molecular Cancer

Zhang, Yaxiong Y; Chang, Lianpeng L; Yang, Yunpeng Y; Fang, Wenfeng W; Guan, Yanfang Y; Wu, Aiwei A; Hong, Shaodong S; Zhou, Huaqiang H; Chen, Gang G; Chen, Xi X; Zhao, Shen S; Zheng, Qiufan Q; Pan, Hui H; Zhang, Lanjun L; Long, Hao H; Yang, Haoxian H; Wang, Xin X; Wen, Zhesheng Z; Wang, Junye J; Yang, Hong H; Xia, Xuefeng X; Zhao, Yuanyuan Y; Hou, Xue X; Ma, Yuxiang Y; Zhou, Ting T; Zhang, Zhonghan Z; Zhan, Jianhua J; Huang, Yan Y; Zhao, Hongyun H; Zhou, Ningning N; Yi, Xin X; Zhang, Li L

Publication Date: 2019-01-09

Variant appearance in text: EGFR: 2239_2247delTTAAGAGAA; L747_E749del

PubMed Link: 30626401

Variant Present in the following documents:

• 12943_2019_939_MOESM10_ESM.xlsx, sheet 2

View BVdb publication page

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Different subtypes of EGFR exon19 mutation can affect prognosis of patients with non-small cell lung adenocarcinoma.

Plos One

Tian, Yingying Y; Zhao, Jiuzhou J; Ren, Pengfei P; Wang, Bo B; Zhao, Chengzhi C; Shi, Chao C; Wei, Bing B; Ma, Jie J; Guo, Yongjun Y

Publication Date: 2018

Variant appearance in text: EGFR: 2239_2247del; Leu747_Glu749del

PubMed Link: 30383772

Variant Present in the following documents:

• Main text
• pone.0201682.pdf

View BVdb publication page

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