Publications:

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Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing.

Bmc Bioinformatics

Garana, Belinda B BB; Joly, James H JH; Delfarah, Alireza A; Hong, Hyunjun H; Graham, Nicholas A NA

Publication Date: 2023-05-24

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 37226094

Variant Present in the following documents:

• Main text
• 12859_2023_Article_5343.pdf

View BVdb publication page

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Monitoring EGFR-lung cancer evolution: a possible beginning of a "methylation era" in TKI resistance prediction.

Frontiers In Oncology

Fabrizio, Federico Pio FP; Sparaneo, Angelo A; Muscarella, Lucia Anna LA

Publication Date: 2023

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 37152062

Variant Present in the following documents:

• Main text
• fonc-13-1137384.pdf

View BVdb publication page

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Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer

Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J

Publication Date: 2023-03-31

Variant appearance in text: EGFR: Glu746_Ala750del

PubMed Link: 37004022

Variant Present in the following documents:

• Main text
• 12885_2023_Article_10674.pdf
• 12885_2023_10674_MOESM3_ESM.xlsx, sheet 1
• 12885_2023_10674_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial.

Nature Medicine

Cascone, Tina T; Leung, Cheuk H CH; Weissferdt, Annikka A; Pataer, Apar A; Carter, Brett W BW; Godoy, Myrna C B MCB; Feldman, Hope H; William, William N WN; Xi, Yuanxin Y; Basu, Sreyashi S; Sun, Jing Jing JJ; Yadav, Shalini S SS; Rojas Alvarez, Frank R FR; Lee, Younghee Y; Mishra, Aditya K AK; Chen, Lili L; Pradhan, Monika M; Guo, Haiping H; Sinjab, Ansam A; Zhou, Nicolas N; Negrao, Marcelo V MV; Le, Xiuning X; Gay, Carl M CM; Tsao, Anne S AS; Byers, Lauren Averett LA; Altan, Mehmet M; Glisson, Bonnie S BS; Fossella, Frank V FV; Elamin, Yasir Y YY; Blumenschein, George G; Zhang, Jianjun J; Skoulidis, Ferdinandos F; Wu, Jia J; Mehran, Reza J RJ; Rice, David C DC; Walsh, Garrett L GL; Hofstetter, Wayne L WL; Rajaram, Ravi R; Antonoff, Mara B MB; Fujimoto, Junya J; Solis, Luisa M LM; Parra, Edwin R ER; Haymaker, Cara C; Wistuba, Ignacio I II; Swisher, Stephen G SG; Vaporciyan, Ara A AA; Lin, Heather Y HY; Wang, Jing J; Gibbons, Don L DL; Jack Lee, J J; Ajami, Nadim J NJ; Wargo, Jennifer A JA; Allison, James P JP; Sharma, Padmanee P; Kadara, Humam H; Heymach, John V JV; Sepesi, Boris B

Publication Date: 2023-03-16

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 36928818

Variant Present in the following documents:

• 41591_2022_2189_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Development and validation of a mutation-based model to predict immunotherapeutic efficacy in NSCLC.

Frontiers In Oncology

He, Ping P; Liu, Jie J; Xu, Qingyuan Q; Ma, Huaijun H; Niu, Beifang B; Huang, Gang G; Wu, Wei W

Publication Date: 2023

Variant appearance in text: EGFR: 2236_2250del; rs727504233

PubMed Link: 36910641

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 8

View BVdb publication page

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Performance Characteristics of Oncomine Focus Assay for Theranostic Analysis of Solid Tumors, A (21-Months) Real-Life Study.

Diagnostics (Basel, Switzerland)

Bamba-Funck, Jessica J; Fabre, Emmanuelle E EE; Kambouchner, Marianne M; Schischmanoff, Olivier O

Publication Date: 2023-03-01

Variant appearance in text: EGFR: Glu746_Ala750del

PubMed Link: 36900081

Variant Present in the following documents:

• Main text
• diagnostics-13-00937.pdf

View BVdb publication page

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: EGFR: 2236_2250del; Glu746_Ala750del; rs727504233

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6

View BVdb publication page

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Analysis of acquired resistance mechanisms to osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer from the AURA3 trial.

Nature Communications

Chmielecki, Juliann J; Mok, Tony T; Wu, Yi-Long YL; Han, Ji-Youn JY; Ahn, Myung-Ju MJ; Ramalingam, Suresh S SS; John, Thomas T; Okamoto, Isamu I; Yang, James Chih-Hsin JC; Shepherd, Frances A FA; Bulusu, Krishna C KC; Laus, Gianluca G; Collins, Barbara B; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Papadimitrakopoulou, Vassiliki V

Publication Date: 2023-02-27

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA

PubMed Link: 36849516

Variant Present in the following documents:

• 41467_2023_35962_MOESM2_ESM.xlsx, sheet 1
• 41467_2023_35962_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer.

Nature Communications

Chmielecki, Juliann J; Gray, Jhanelle E JE; Cheng, Ying Y; Ohe, Yuichiro Y; Imamura, Fumio F; Cho, Byoung Chul BC; Lin, Meng-Chih MC; Majem, Margarita M; Shah, Riyaz R; Rukazenkov, Yuri Y; Todd, Alexander A; Markovets, Aleksandra A; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Ramalingam, Suresh S SS

Publication Date: 2023-02-27

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA

PubMed Link: 36849494

Variant Present in the following documents:

• 41467_2023_35961_MOESM3_ESM.xlsx, sheet 2
• 41467_2023_35961_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: EGFR: 2236_2250del; Glu746_Ala750del

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Mutational Analysis of EGFR Mutations in Non-Small Cell Lung Carcinoma-An Indian Perspective of 212 Patients.

International Journal Of Environmental Research And Public Health

Kaler, Amrit Kaur AK; Patel, Khushi K; Patil, Harshali H; Tiwarekar, Yash Y; Kulkarni, Bijal B; Hastak, Meenal M; Athikari, Nivetha N; Rane, Samrudhi S; Nikam, Ankita A; Umarji, Smita S; Shaikh, Imran I; Goyle, Sandeep S; Mistry, Rajesh R

Publication Date: 2022-12-31

Variant appearance in text: EGFR: 2236_2250del

PubMed Link: 36613084

Variant Present in the following documents:

• ijerph-20-00758.pdf

View BVdb publication page

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Case report: olaparib use in metastatic lung adenocarcinoma with BRCA2 pathogenic variant.

Cold Spring Harbor Molecular Case Studies

Soon Jian Hao, Jonathan J; Hoai, Chan Sock CS; Weng, Daniel Tan Shao DTS; Ngeow, Joanne J; Chiang, Jianbang J

Publication Date: 2022-12

Variant appearance in text: EGFR: 2236_2250del; E746_A750del

PubMed Link: 36577523

Variant Present in the following documents:

• supp_mcs.a006223_Supplemental_Material.pdf

View BVdb publication page

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Clinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy.

British Journal Of Cancer

Cifuentes, Guadalupe A GA; Santiago, Adrián A; Méndez Blanco, Lucía L; Fueyo, María M; López Martínez, Esther E; Soria, Raquel R; Martín López, Irene I; Cucarella Beltrán, Pepa P; Pardo-Coto, Pablo P; Rodriguez-Rubi, David D; Urquilla, Karla K; Durán, Noelia S NS; Álvarez, Rebeca R; Lago, Claudia G CG; Otero, Andrea A; Diñeiro, Marta M; Capín, Raquel R; Cadiñanos, Juan J; Cabanillas, Rubén R

Publication Date: 2022-12-22

Variant appearance in text: EGFR: 2236_2250del; Glu746_Ala750del

PubMed Link: 36550207

Variant Present in the following documents:

• Main text
• 41416_2022_2102_MOESM6_ESM.xlsx, sheet 1
• 41416_2022_Article_2102.pdf

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA; E746_A750del

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 3
• Table_2.xlsx, sheet 2

View BVdb publication page

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Clinical Potential of Circulating Cell-Free DNA (cfDNA) for Longitudinally Monitoring Clinical Outcomes in the First-Line Setting of Non-Small-Cell Lung Cancer (NSCLC): A Real-World Prospective Study.

Cancers

Gristina, Valerio V; Barraco, Nadia N; La Mantia, Maria M; Castellana, Luisa L; Insalaco, Lavinia L; Bono, Marco M; Perez, Alessandro A; Sardo, Delia D; Inguglia, Sara S; Iacono, Federica F; Cutaia, Sofia S; Bazan Russo, Tancredi Didier TD; Francini, Edoardo E; Incorvaia, Lorena L; Badalamenti, Giuseppe G; Russo, Antonio A; Galvano, Antonio A; Bazan, Viviana V

Publication Date: 2022-12-06

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 36497493

Variant Present in the following documents:

• cancers-14-06013.pdf

View BVdb publication page

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Validation and Clinical Application of ONCOaccuPanel for Targeted Next-Generation Sequencing of Solid Tumors.

Cancer Research And Treatment

Kim, Moonsik M; Lee, Changseon C; Hong, Juyeon J; Kim, Juhee J; Jeong, Ji Yun JY; Park, Nora Jee-Young NJ; Kim, Ji-Eun JE; Park, Ji Young JY

Publication Date: 2022-11-25

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 36470260

Variant Present in the following documents:

• crt-2022-891.pdf
• crt-2022-891-Supplementary-Table-1.pdf
• crt-2022-891-Supplementary-Table-4.pdf

View BVdb publication page

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Systematic assessment and optimizing algorithm of tumor mutational burden calculation and their implications in clinical decision-making.

Frontiers In Oncology

Sun, Daqiang D; Xu, Meilin M; Pan, Chaohu C; Tang, Hongzhen H; Wang, Peng P; Wu, Dongfang D; Luo, Haitao H

Publication Date: 2022

Variant appearance in text: EGFR: 2236_2250del

PubMed Link: 36425562

Variant Present in the following documents:

• Table_3.xlsx, sheet 1
• Table_4.xlsx, sheet 1

View BVdb publication page

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Proposal of a novel pipeline involving precise bronchoscopy of distal peripheral pulmonary lesions for genetic testing.

Scientific Reports

Takata, So S; Miyake, Kotaro K; Maeda, Daichi D; Hatake, Kazue K; Nagatomo, Izumi I; Shiroyama, Takayuki T; Masuhiro, Kentaro K; Yaga, Moto M; Shirai, Yuya Y; Mitsui, Yuichi Y; Yachida, Shinichi S; Kumanogoh, Atsushi A

Publication Date: 2022-11-17

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 36396864

Variant Present in the following documents:

• 41598_2022_Article_24372.pdf

View BVdb publication page

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Case report: A case report and literature review about Pathological transformation of lung adenosquamous cell carcinoma.

Frontiers In Oncology

Ge-Ge, Liang L; Cuicui, Geng G; Leiqiang, Li L; Yongcang, Tian T; Jiangang, Ma M; Yiwen, Ou O; Li-Zhe, Sun S

Publication Date: 2022

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 36330480

Variant Present in the following documents:

• Main text
• fonc-12-1029679.pdf

View BVdb publication page

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Improving Time-to-Treatment for Advanced Non-Small Cell Lung Cancer Patients through Faster Single Gene EGFR Testing Using the Idylla™ EGFR Testing Platform.

Current Oncology (Toronto, Ont.)

Banyi, Norbert N; Alex, Deepu D; Hughesman, Curtis C; McNeil, Kelly K; N Ionescu, Diana D; Ma, Carmen C; Yip, Stephen S; Melosky, Barbara B

Publication Date: 2022-10-18

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA

PubMed Link: 36290901

Variant Present in the following documents:

• curroncol-29-00624.pdf

View BVdb publication page

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Analytical and clinical validation of a custom 15-gene next-generation sequencing panel for the evaluation of circulating tumor DNA mutations in patients with advanced non-small-cell lung cancer.

Plos One

Chow, Yock Ping YP; Zainul Abidin, Norziha N; Kow, Ken Siong KS; Tho, Lye Mun LM; Wong, Chieh Lee CL

Publication Date: 2022

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 36256645

Variant Present in the following documents:

• pone.0276161.s002.xlsx, sheet 1

View BVdb publication page

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Liquid biopsy using ascitic fluid and pleural effusion supernatants for genomic profiling in gastrointestinal and lung cancers.

Bmc Cancer

Wu, Huita H; Ji, Haonan H; Yang, Wenhui W; Zhang, Min M; Guo, Yifang Y; Li, Bangkai B; Wang, Jiayin J; Chen, Rongrong R; Chen, Yuan Y; Wang, Xin X

Publication Date: 2022-09-27

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 36167530

Variant Present in the following documents:

• 12885_2022_9922_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Landscape of EGFR mutations in lung adenocarcinoma: a single institute experience with comparison of PANAMutyper testing and targeted next-generation sequencing.

Journal Of Pathology And Translational Medicine

Lee, Jeonghyo J; Han, Yeon Bi YB; Kwon, Hyun Jung HJ; Lee, Song Kook SK; Kim, Hyojin H; Chung, Jin-Haeng JH

Publication Date: 2022-09

Variant appearance in text: EGFR: 2236_2250del; E746_A750del

PubMed Link: 36128861

Variant Present in the following documents:

• jptm-2022-06-11-suppl1.pdf

View BVdb publication page

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Utilization of cytologic cell blocks for targeted sequencing of solid tumors.

Cancer Medicine

Vormittag-Nocito, Erica E; Kumar, Ravindra R; Narayan, Kunwar Digvijay KD; Chen, Zhengjia Z; David, Odile O; Behm, Frederick F; Mohapatra, Gayatry G

Publication Date: 2022-09-20

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 36125633

Variant Present in the following documents:

• Main text
• CAM4-12-4042-s001.xlsx, sheet 1
• CAM4-12-4042.pdf

View BVdb publication page

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Comprehensive characterization of genomic and radiologic features reveals distinct driver patterns of RTK/RAS pathway in ground-glass opacity pulmonary nodules.

International Journal Of Cancer

Yu, Fenglei F; Peng, Muyun M; Bai, Jing J; Zhu, Xiuli X; Zhang, Bingyu B; Tang, Jingqun J; Liu, Wenliang W; Chen, Chen C; Wang, Xiang X; Chen, Mingjiu M; Tan, Sichuang S; Sun, Yi Y; Liang, Qingchun Q; Li, Jina J; Hu, Yan Y; Liao, Aihui A; Hu, Huali H; He, Yu Y; Xiao, Xiao X; Wang, Bin B; Xing, Guanlan G; Xu, Yaping Y; Chen, Rongrong R; Xia, Xuefeng X; Chen, Xiaofeng X

Publication Date: 2022-12-01

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 36029220

Variant Present in the following documents:

• IJC-151-2020-s001.pdf
• IJC-151-2020.pdf

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA; Glu746_Ala750del; rs727504233

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA; E746_A750del

PubMed Link: 35814426

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

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Clinical Characteristics, Co-Mutations, and Treatment Outcomes in Advanced Non-Small-Cell Lung Cancer Patients With the BRAF-V600E Mutation.

Frontiers In Oncology

Qu, Jingjing J; Shen, Qian Q; Li, Yuping Y; Kalyani, Farhin Shaheed FS; Liu, Li L; Zhou, Jianya J; Zhou, Jianying J

Publication Date: 2022

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 35814395

Variant Present in the following documents:

• Main text
• fonc-12-911303.pdf

View BVdb publication page

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Differences in actionable genomic alterations between brain metastases and non‑brain metastases in patients with non‑small cell lung cancer.

International Journal Of Oncology

Nian, Rui R; Jiang, Huihui H; Zhao, Jiangman J; Hou, Wanle W; Zhang, Hua H; Ma, Jiangtao J; Lv, Pengbiao P; Jiang, Lisha L; Wang, Yongpan Y; Xu, Yue Y; Wu, Shouxin S; Lou, Jingwei J; Li, Wanjun W

Publication Date: 2022-09

Variant appearance in text: EGFR: 2236_2250del

PubMed Link: 35796015

Variant Present in the following documents:

• Supplementary_Data6.xlsx, sheet 1

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA; E746_A750del

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW

Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA; Glu746_Ala750del

PubMed Link: 35606799

Variant Present in the following documents:

• 41021_2022_248_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Molecular landscape and therapeutic alterations in Asian soft-tissue sarcoma patients.

Cancer Medicine

Gan, Meifu M; Zhang, Chen C; Qiu, Liqing L; Wang, Yue Y; Bao, Hua H; Yu, Ruoying R; Liu, Rui R; Wu, Xue X; Shao, Yang Y; Hou, Peifeng P; Fei, Zhenglei Z

Publication Date: 2022-11

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA; E746_A750del

PubMed Link: 35586877

Variant Present in the following documents:

• CAM4-11-4070-s004.xlsx, sheet 1

View BVdb publication page

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TP53 Loss of Heterozygosity Induces De Novo SCLC Formation in EGFR-Mutated Lung Adenocarcinoma: A Case Report.

Jto Clinical And Research Reports

Kunimasa, Kei K; Hirotsu, Yosuke Y; Amemiya, Kenji K; Nakamura, Harumi H; Nishino, Kazumi K; Honma, Keiichiro K; Okami, Jiro J; Omata, Masao M; Kumagai, Toru T

Publication Date: 2022-05

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 35498386

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Genetic Characteristics Associated With Drug Resistance in Lung Cancer and Colorectal Cancer Using Whole Exome Sequencing of Cell-Free DNA.

Frontiers In Oncology

Lee, Jong Won JW; Park, Young Soo YS; Choi, Jung Yoon JY; Chang, Won Jin WJ; Lee, Soohyeon S; Sung, Jae Sook JS; Kim, Boyeon B; Lee, Saet Byeol SB; Lee, Sung Yong SY; Choi, Jungmin J; Kim, Yeul Hong YH

Publication Date: 2022

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 35402275

Variant Present in the following documents:

• Main text
• fonc-12-843561.pdf

View BVdb publication page

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PEAC: An Ultrasensitive and Cost-Effective MRD Detection System in Non-small Cell Lung Cancer Using Plasma Specimen.

Frontiers In Medicine

Xu, Jianping J; Pu, Yue Y; Lin, Rui R; Xiao, Shanshan S; Fu, Yingxue Y; Wang, Tao T

Publication Date: 2022

Variant appearance in text: EGFR: 2236_2250del; E746_A750del

PubMed Link: 35308511

Variant Present in the following documents:

• Table_7.xlsx, sheet 1

View BVdb publication page

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Characterization of non-small cell lung cancer transforming to small cell lung cancer and its response to EGFR-TKI: a case report.

Annals Of Translational Medicine

Fang, Guotao G; Liu, Weiwei W; Shang, Yanhong Y; Huo, Ran R; Shi, Xiaoliang X; Wang, Yanan Y; Li, Jinghua J

Publication Date: 2022-01

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 35282065

Variant Present in the following documents:

• Main text
• atm-10-02-115.pdf

View BVdb publication page

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The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer.

Frontiers In Oncology

Cai, Jun J; Jiang, Huihui H; Li, Shuqing S; Yan, Xiaoxia X; Wang, Meng M; Li, Na N; Zhu, Cuimin C; Dong, Hui H; Wang, Dongjuan D; Xu, Yue Y; Xie, Hui H; Wu, Shouxin S; Lou, Jingwei J; Zhao, Jiangman J; Li, Qingshan Q

Publication Date: 2021

Variant appearance in text: EGFR: 2236_2250del

PubMed Link: 35273907

Variant Present in the following documents:

• Table_8.xlsx, sheet 1

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA; E746_A750del

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine

Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R

Publication Date: 2022-05

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA; Glu746_Ala750del

PubMed Link: 35244186

Variant Present in the following documents:

• Supplementary_Data2.xlsx, sheet 1
• Supplementary_Data3.xlsx, sheet 1

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Complementing Tissue Testing With Plasma Mutation Profiling Improves Therapeutic Decision-Making for Patients With Lung Cancer.

Frontiers In Medicine

Choudhury, Yukti Y; Tan, Min-Han MH; Shi, Jun Li JL; Tee, Augustine A; Ngeow, Kao Chin KC; Poh, Jonathan J; Goh, Ruth Rosalyn RR; Mong, Jamie J

Publication Date: 2022

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 35223889

Variant Present in the following documents:

• Main text
• fmed-09-758464.pdf

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Detection of EGFR mutations in non-small cell lung cancer by droplet digital PCR.

Plos One

Williamson, Drew F K DFK; Marris, Sean R N SRN; Rojas-Rudilla, Vanesa V; Bruce, Jacqueline L JL; Paweletz, Cloud P CP; Oxnard, Geoffrey R GR; Sholl, Lynette M LM; Dong, Fei F

Publication Date: 2022

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 35202431

Variant Present in the following documents:

• Main text
• pone.0264201.pdf

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Identifying Actionable Variants Using Capture-Based Targeted Sequencing in 563 Patients With Non-Small Cell Lung Carcinoma.

Frontiers In Oncology

Jiang, Haiping H; Wang, Yinan Y; Xu, Hanlin H; Lei, Wei W; Yu, Xiaoyun X; Tian, Haiying H; Meng, Cong C; Wang, Xueying X; Zhao, Zicheng Z; Jin, Xiangfeng X

Publication Date: 2021

Variant appearance in text: EGFR: 2236_2250del; E746_A750del; rs727504233

PubMed Link: 35186718

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Establishment and application of a method of next generation sequencing of 285 genes in lung cancer based on Ion-Proton platform.

Translational Cancer Research

Chen, Yu Y; Zhang, Xu-Chao XC; Yan, Wen-Qing WQ; Guo, Wei-Bang WB; Xie, Zhi Z; Lu, Dan-Xia DX; Lv, Zhi-Yi ZY; Chen, Zhi-Hong ZH; Su, Jian J

Publication Date: 2020-07

Variant appearance in text: EGFR: 2236_2250delGAATTAAGAGAAGCA; Glu746_Ala750del

PubMed Link: 35117791

Variant Present in the following documents:

• Main text

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EGFR exon 19 deletion switch and development of p.L792Q mutation as a new resistance mechanism to osimertinib: a case report and literature review.

Translational Cancer Research

Pisapia, Pasquale P; Rocco, Danilo D; Pepe, Francesco F; De Luca, Caterina C; Battiloro, Ciro C; Smeraglio, Riccardo R; Cieri, Miriam M; Bellevicine, Claudio C; Troncone, Giancarlo G; Malapelle, Umberto U

Publication Date: 2019-01

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 35117065

Variant Present in the following documents:

• Main text

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Prospective analysis of liquid biopsies of advanced non-small cell lung cancer patients after progression to targeted therapies using GeneReader NGS platform.

Translational Cancer Research

Mayo de Las Casas, Clara C; Garzón-Ibañez, Mónica M; Jordana-Ariza, Núria N; Viteri-Ramírez, Santiago S; Moya-Horno, Irene I; Karachaliou, Niki N; Yeste, Zaira Z; Campos, Raquel R; Villatoro, Sergi S; Balada-Bel, Ariadna A; García-Peláez, Beatriz B; Reguart, Noemí N; Teixidó, Cristina C; Jantús, Eloisa E; Calabuig, Silvia S; Aguado, Cristina C; Giménez-Capitán, Ana A; Román-Lladó, Ruth R; Pérez-Rosado, Ana A; Catalán, Maria José MJ; Bertrán-Alamillo, Jordi J; García-Román, Silvia S; Rodriguez, Sonia S; Alonso, Lidia L; Aldeguer, Erika E; Martínez-Bueno, Alejandro A; González-Cao, Maria M; Aguilar Hernandez, Andrés A; Garcia-Mosquera, Juan J; de Los Llanos Gil, Maria M; Fernandez, Manuel M; Rosell, Rafael R; Molina-Vila, Miguel Ángel MÁ

Publication Date: 2019-01

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 35117060

Variant Present in the following documents:

• Main text

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Molecular genetic profiling of small cell lung carcinoma in a Chinese cohort.

Translational Cancer Research

Wang, Zeng Z; Jiang, Zhiming Z; Lu, Hongyang H

Publication Date: 2019-02

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 35116754

Variant Present in the following documents:

• Main text

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The clinical value of circulating tumor DNA detection in advanced non-small cell lung cancer.

Translational Cancer Research

Lin, Xiao X; Dong, Wentao W; Lai, Xiaojing X; Feng, Wei W; Yu, Xiaofu X; Gu, Qing Q; Wang, Chunyang C; Xiao, Wen W; Zheng, Xiao X

Publication Date: 2019-02

Variant appearance in text: EGFR: 2236_2250del; E746_A750del

PubMed Link: 35116746

Variant Present in the following documents:

• Main text

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Investigation of PALB2 Mutation and Correlation With Immunotherapy Biomarker in Chinese Non-Small Cell Lung Cancer Patients.

Frontiers In Oncology

Zhang, Jiexia J; Tang, Shuangfeng S; Zhang, Chunning C; Li, Mingyao M; Zheng, Yating Y; Hu, Xue X; Huang, Mengli M; Cheng, Xiangyang X

Publication Date: 2021

Variant appearance in text: EGFR: 2236_2250del; E746_A750del

PubMed Link: 35087742

Variant Present in the following documents:

• Table_2.xlsx, sheet 1

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Assessment of Anti-tumor Efficacy of Osimertinib in Non-Small Cell Lung Cancer Patients by Liquid Biopsy Using Bronchoalveolar Lavage Fluid, Plasma, or Pleural Effusion.

Cancer Research And Treatment

Kim, Yeon Joo YJ; Ji, Won Jun WJ; Lee, Jae-Cheol JC; Chun, Sung-Min SM; Choi, Chang-Min CM

Publication Date: 2022-10

Variant appearance in text: EGFR: E746_A750del

PubMed Link: 35038824

Variant Present in the following documents:

• crt-2021-857_S5-Table.pdf

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