Publications:

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: EGFR: 2237A>G; E746G

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 2
• Table_2.xlsx, sheet 3

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Immune checkpoint inhibitors for PD-1/PD-L1 axis in combination with other immunotherapies and targeted therapies for non-small cell lung cancer.

Frontiers In Oncology

Mussafi, Ofek O; Mei, Jie J; Mao, Wenjun W; Wan, Yuan Y

Publication Date: 2022

Variant appearance in text: EGFR: E746G

PubMed Link: 36059606

Variant Present in the following documents:

• Main text
• fonc-12-948405.pdf

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: EGFR: Glu746Gly

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

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Surgical resection of brain metastases prolongs overall survival in non-small-cell lung cancer.

American Journal Of Cancer Research

Yen, Chia-Te CT; Wu, Wen-Jui WJ; Chen, Yen-Ting YT; Chang, Wei-Chin WC; Yang, Sheng-Hsiung SH; Shen, Sheng-Yeh SY; Su, Jian J; Chen, Hsuan-Yu HY

Publication Date: 2021

Variant appearance in text: EGFR: E746G

PubMed Link: 35018249

Variant Present in the following documents:

• Main text

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: E746G

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Glu746Gly

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Glu746Gly

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: EGFR: E746G

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: EGFR: E746G

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11

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Comparison of different semi-automated cfDNA extraction methods in combination with UMI-based targeted sequencing.

Oncotarget

Streubel, Anna A; Stenzinger, Albrecht A; Stephan-Falkenau, Susann S; Kollmeier, Jens J; Misch, Daniel D; Blum, Torsten Gerriet TG; Bauer, Torsten T; Landt, Olfert O; Am Ende, Alexander A; Schirmacher, Peter P; Mairinger, Thomas T; Endris, Volker V

Publication Date: 2019-10-01

Variant appearance in text: EGFR: Glu746Gly

PubMed Link: 31620244

Variant Present in the following documents:

• oncotarget-10-5690-s003.xlsx, sheet 1

View BVdb publication page

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Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Ikemura, Shinnosuke S; Yasuda, Hiroyuki H; Matsumoto, Shingo S; Kamada, Mayumi M; Hamamoto, Junko J; Masuzawa, Keita K; Kobayashi, Keigo K; Manabe, Tadashi T; Arai, Daisuke D; Nakachi, Ichiro I; Kawada, Ichiro I; Ishioka, Kota K; Nakamura, Morio M; Namkoong, Ho H; Naoki, Katsuhiko K; Ono, Fumie F; Araki, Mitsugu M; Kanada, Ryo R; Ma, Biao B; Hayashi, Yuichiro Y; Mimaki, Sachiyo S; Yoh, Kiyotaka K; Kobayashi, Susumu S SS; Kohno, Takashi T; Okuno, Yasushi Y; Goto, Koichi K; Tsuchihara, Katsuya K; Soejima, Kenzo K

Publication Date: 2019-05-14

Variant appearance in text: EGFR: E746G

PubMed Link: 31043566

Variant Present in the following documents:

• pnas.1819430116.sapp.pdf

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Heterogeneous Responses to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs) in Patients with Uncommon EGFR Mutations: New Insights and Future Perspectives in this Complex Clinical Scenario.

International Journal Of Molecular Sciences

Russo, Alessandro A; Franchina, Tindara T; Ricciardi, Giuseppina G; Battaglia, Alessandra A; Picciotto, Maria M; Adamo, Vincenzo V

Publication Date: 2019-03-21

Variant appearance in text: EGFR: E746G

PubMed Link: 30901844

Variant Present in the following documents:

• Main text
• ijms-20-01431.pdf

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EGFR with TKI-sensitive mutations in exon 19 is highly expressed and frequently detected in Chinese patients with lung squamous carcinoma.

Oncotargets And Therapy

Memon, Aadil Ahmed AA; Zhang, Haiping H; Gu, Ye Y; Luo, Qian Q; Shi, Jiajun J; Deng, Zixin Z; Ma, Jian J; Ma, Wei W

Publication Date: 2017

Variant appearance in text: EGFR: Glu746Gly

PubMed Link: 29075127

Variant Present in the following documents:

• Main text
• ott-10-4607.pdf

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: ERBB: 2237A>G

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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Continuous epidermal growth factor receptor-tyrosine kinase inhibitor administration in primary lung adenocarcinoma patients harboring favorable mutations with controlled target lung tumors dose not hinder survival benefit despite small new lesions.

Biomedical Journal

Hsu, Ping-Chih PC; Chiu, Li-Chung LC; Li, Shih-Hong SH; Chen, Chih-Hung CH; Wang, Chih-Liang CL; Kao, Kuo-Chin KC; Chang, John Wen-Chang JW; Wang, Chih-Wei CW; Yu, Chih-Teng CT; Chung, Fu-Tsai FT; Yang, Cheng-Ta CT; Liu, Chien-Ying CY

Publication Date: 2016-04

Variant appearance in text: EGFR: E746G

PubMed Link: 27372167

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Impact of EGFR mutation detection methods on the efficacy of erlotinib in patients with advanced EGFR-wild type lung adenocarcinoma.

Plos One

Tseng, Jeng-Sen JS; Wang, Chih-Liang CL; Huang, Ming-Shyan MS; Chen, Chung-Yu CY; Chang, Cheng-Yu CY; Yang, Tsung-Ying TY; Tsai, Chi-Ren CR; Chen, Kun-Chieh KC; Hsu, Kuo-Hsuan KH; Tsai, Meen-Hsin MH; Yu, Sung-Liang SL; Su, Kang-Yi KY; Wu, Chih-Wei CW; Yang, Cheng-Ta CT; Chen, Yuh-Min YM; Chang, Gee-Chen GC

Publication Date: 2014

Variant appearance in text: EGFR: E746G

PubMed Link: 25215536

Variant Present in the following documents:

• pone.0107160.s004.pdf

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