EGFR c.2239_2252delinsCA ;(p.L747_T751delinsQ)

Variant ID: 7-55242469-TTAAGAGAAGCAAC-CA

NM_005228.3(EGFR):c.2239_2252delinsCA;(p.L747_T751delinsQ)

This variant was identified in 4 publications

View GRCh38 version.



Variant-Specific Resource Links:
gnomAD v2.1.1
Mutalizer Name Checker
Google
UCSC Genome Browser
ClinVar
dbSNP

Publications:

Analysis of acquired resistance mechanisms to osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer from the AURA3 trial.

Nature Communications
Chmielecki, Juliann J; Mok, Tony T; Wu, Yi-Long YL; Han, Ji-Youn JY; Ahn, Myung-Ju MJ; Ramalingam, Suresh S SS; John, Thomas T; Okamoto, Isamu I; Yang, James Chih-Hsin JC; Shepherd, Frances A FA; Bulusu, Krishna C KC; Laus, Gianluca G; Collins, Barbara B; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Papadimitrakopoulou, Vassiliki V
Publication Date: 2023-02-27

Variant appearance in text: EGFR: 2239_2252delTTAAGAGAAGCAACinsCA
PubMed Link: 36849516
Variant Present in the following documents:
  • 41467_2023_35962_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page


Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2239_2252delTTAAGAGAAGCAACinsCA
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page


Oncogenic driver mutations in Swiss never smoker patients with lung adenocarcinoma and correlation with clinicopathologic characteristics and outcome.

Plos One
Grosse, Claudia C; Soltermann, Alex A; Rechsteiner, Markus M; Grosse, Alexandra A
Publication Date: 2019

Variant appearance in text: EGFR: 2239_2252delinsCA
PubMed Link: 31386689
Variant Present in the following documents:
  • Main text
  • pone.0220691.pdf
View BVdb publication page


Clinical mutational profiling of 1006 lung cancers by next generation sequencing.

Oncotarget
Illei, Peter B PB; Belchis, Deborah D; Tseng, Li-Hui LH; Nguyen, Doreen D; De Marchi, Federico F; Haley, Lisa L; Riel, Stacy S; Beierl, Katie K; Zheng, Gang G; Brahmer, Julie R JR; Askin, Frederic B FB; Gocke, Christopher D CD; Eshleman, James R JR; Forde, Patrick M PM; Lin, Ming-Tseh MT
Publication Date: 2017-11-14

Variant appearance in text: EGFR: 2239_2252delinsCA
PubMed Link: 29228562
Variant Present in the following documents:
  • oncotarget-08-96684.pdf
View BVdb publication page