EGFR c.2242_2244del ;(p.R748del)

Variant ID: 7-55242470-TAAG-T

NM_005228.3(EGFR):c.2242_2244del;(p.R748del)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-04

Variant appearance in text: EGFR: R748del
PubMed Link: 35304574
Variant Present in the following documents:
  • 41388_2022_Article_2263.pdf
View BVdb publication page



Analysis of Predictive Biomarkers in Patients With Lung Adenocarcinoma From Southern Brazil Reveals a Distinct Profile From Other Regions of the Country.

Journal Of Global Oncology
Andreis, Tiago F TF; Correa, Bruno S BS; Vianna, Fernanda S FS; De-Paris, Fernanda F; Siebert, Marina M; Leistner-Segal, Sandra S; Hahn, Eriza C EC; Ulbrich, Jane M JM; Rivero, Luis F R LFR; De Oliveira, Francine H FH; Lorandi, Vinícius V; Ashton-Prolla, Patricia P; Macedo, Gabriel S GS
Publication Date: 2019-09

Variant appearance in text: EGFR: Arg748del
PubMed Link: 31532708
Variant Present in the following documents:
  • JGO.19.00174.pdf
View BVdb publication page



Intrinsic resistance to EGFR-Tyrosine Kinase Inhibitors in EGFR-Mutant Non-Small Cell Lung Cancer: Differences and Similarities with Acquired Resistance.

Cancers
Santoni-Rugiu, Eric E; Melchior, Linea C LC; Urbanska, Edyta M EM; Jakobsen, Jan N JN; Stricker, Karin de K; Grauslund, Morten M; Sørensen, Jens B JB
Publication Date: 2019-07-01

Variant appearance in text: EGFR: R748del
PubMed Link: 31266248
Variant Present in the following documents:
  • Main text
  • cancers-11-00923.pdf
View BVdb publication page



Concomitant driver mutations in advanced EGFR-mutated non-small-cell lung cancer and their impact on erlotinib treatment.

Oncotarget
Jakobsen, Jan Nyrop JN; Santoni-Rugiu, Eric E; Grauslund, Morten M; Melchior, Linea L; Sørensen, Jens Benn JB
Publication Date: 2018-05-25

Variant appearance in text: EGFR: R748del
PubMed Link: 29899852
Variant Present in the following documents:
  • oncotarget-09-26195.pdf
View BVdb publication page



Validation of liquid biopsy: plasma cell-free DNA testing in clinical management of advanced non-small cell lung cancer.

Lung Cancer (Auckland, N.Z.)
Veldore, Vidya H VH; Choughule, Anuradha A; Routhu, Tejaswi T; Mandloi, Nitin N; Noronha, Vanita V; Joshi, Amit A; Dutt, Amit A; Gupta, Ravi R; Vedam, Ramprasad R; Prabhash, Kumar K
Publication Date: 2018

Variant appearance in text: EGFR: R748del
PubMed Link: 29379323
Variant Present in the following documents:
  • Main text
  • lctt-9-001.pdf
View BVdb publication page



Variant Review with the Integrative Genomics Viewer.

Cancer Research
Robinson, James T JT; Thorvaldsdóttir, Helga H; Wenger, Aaron M AM; Zehir, Ahmet A; Mesirov, Jill P JP
Publication Date: 2017-11-01

Variant appearance in text: EGFR: R748del
PubMed Link: 29092934
Variant Present in the following documents:
  • Main text
View BVdb publication page



EGFR and K-Ras mutations in women with lung adenocarcinoma: implications for treatment strategy definition.

Journal Of Experimental & Clinical Cancer Research : Cr
Rotella, Virginia V; Fornaro, Lorenzo L; Vasile, Enrico E; Tibaldi, Carmelo C; Boldrini, Laura L; Chella, Antonio A; D'Incecco, Armida A; Cirigliano, Giovanna G; Chioni, Aldo A; Lupi, Cristiana C; Sensi, Elisa E; Ginocchi, Laura L; Giovannelli, Simona S; Pennucci, Maria Cristina MC; Fontanini, Gabriella G; Baldini, Editta E
Publication Date: 2014-10-11

Variant appearance in text: EGFR: R748del
PubMed Link: 25300933
Variant Present in the following documents:
  • Main text
  • 13046_2014_Article_77.pdf
View BVdb publication page



Spatial and temporal genetic heterogeneity of epidermal growth factor receptor gene status in a patient with non-small cell lung cancer: a case report.

Journal Of Medical Case Reports
Ogata, Makoto M; Shimizu, Toshiki T; Yokoi, Takashi T; Nomura, Shosaku S
Publication Date: 2011-11-22

Variant appearance in text: EGFR: R748del
PubMed Link: 22108465
Variant Present in the following documents:
  • Main text
View BVdb publication page



Benchmarking of mutation diagnostics in clinical lung cancer specimens.

Plos One
Querings, Silvia S; Altmüller, Janine J; Ansén, Sascha S; Zander, Thomas T; Seidel, Danila D; Gabler, Franziska F; Peifer, Martin M; Markert, Eva E; Stemshorn, Kathryn K; Timmermann, Bernd B; Saal, Beate B; Klose, Stefan S; Ernestus, Karen K; Scheffler, Matthias M; Engel-Riedel, Walburga W; Stoelben, Erich E; Brambilla, Elisabeth E; Wolf, Jürgen J; Nürnberg, Peter P; Thomas, Roman K RK
Publication Date: 2011-05-05

Variant appearance in text: EGFR: R748del
PubMed Link: 21573178
Variant Present in the following documents:
  • Main text
  • pone.0019601.pdf
View BVdb publication page