EGFR c.2257_2259del ;(p.P753del)

Variant ID: 7-55242487-TCCG-T

NM_005228.3(EGFR):c.2257_2259del;(p.P753del)

This variant was identified in 19 publications

View GRCh38 version.




Publications:


Intratumor heterogeneity of driver mutations and TMB distribution in 30 early-stage LUAD patients with multiple lesions.

Frontiers In Oncology
Qiu, Yuan Y; Liu, Liping L; Yang, Haihong H; Chen, Hanzhang H; Deng, Qiuhua Q; Xiao, Dakai D; Lin, Yongping Y; Zhu, Changbin C; Li, Weiwei W; Shao, Di D; Jiang, Wenxi W; Wu, Kui K; He, Jianxing J
Publication Date: 2022

Variant appearance in text: EGFR: P753delins
PubMed Link: 36110964
Variant Present in the following documents:
  • Main text
  • fonc-12-952572.pdf
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Performance of an RNA-Based Next-Generation Sequencing Assay for Combined Detection of Clinically Actionable Fusions and Hotspot Mutations in NSCLC.

Jto Clinical And Research Reports
Desmeules, Patrice P; Boudreau, Dominique K DK; Bastien, Nathalie N; Boulanger, Marie-Chloé MC; Bossé, Yohan Y; Joubert, Philippe P; Couture, Christian C
Publication Date: 2022-02

Variant appearance in text: EGFR: P753del
PubMed Link: 35252895
Variant Present in the following documents:
  • Main text
  • main.pdf
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Targeted Next-Generation Sequencing Analysis Predicts the Recurrence in Resected Lung Adenocarcinoma Harboring EGFR Mutations.

Cancers
Kim, In Ae IA; Hur, Jae Young JY; Kim, Hee Joung HJ; Lee, Song Am SA; Hwang, Jae Joon JJ; Kim, Wan Seop WS; Lee, Kye Young KY
Publication Date: 2021-07-20

Variant appearance in text: EGFR: P753delinS
PubMed Link: 34298845
Variant Present in the following documents:
  • Main text
  • cancers-13-03632.pdf
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Patient-derived tumor xenograft and organoid models established from resected pancreatic, duodenal and biliary cancers.

Scientific Reports
Pham, Nhu-An NA; Radulovich, Nikolina N; Ibrahimov, Emin E; Martins-Filho, Sebastiao N SN; Li, Quan Q; Pintilie, Melania M; Weiss, Jessica J; Raghavan, Vibha V; Cabanero, Michael M; Denroche, Robert E RE; Wilson, Julie M JM; Metran-Nascente, Cristiane C; Borgida, Ayelet A; Hutchinson, Shawn S; Dodd, Anna A; Begora, Michael M; Chadwick, Dianne D; Serra, Stefano S; Knox, Jennifer J JJ; Gallinger, Steven S; Hedley, David W DW; Muthuswamy, Lakshmi L; Tsao, Ming-Sound MS
Publication Date: 2021-05-19

Variant appearance in text: EGFR: P753del
PubMed Link: 34011980
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_90049.pdf
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EGFR mutation status in a series of Turkish non-small cell lung cancer patients.

Biomedical Reports
Calibasi-Kocal, Gizem G; Amirfallah, Arsalan A; Sever, Tolga T; Umit Unal, Olcun O; Gurel, Duygu D; Oztop, Ilhan I; Ellidokuz, Hulya H; Basbinar, Yasemin Y
Publication Date: 2020-08

Variant appearance in text: EGFR: Pro753del
PubMed Link: 32509305
Variant Present in the following documents:
  • Main text
View BVdb publication page



Saliva-derived cfDNA is applicable for EGFR mutation detection but not for quantitation analysis in non-small cell lung cancer.

Thoracic Cancer
Ding, Shanshan S; Song, Xingguo X; Geng, Xinran X; Liu, Lele L; Ma, Hongxin H; Wang, Xiujuan X; Wei, Ling L; Xie, Li L; Song, Xianrang X
Publication Date: 2019-10

Variant appearance in text: EGFR: P753del
PubMed Link: 31441578
Variant Present in the following documents:
  • Main text
  • TCA-10-1973.pdf
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Survival Disparities in Black Patients With EGFR-mutated Non-small-cell Lung Cancer.

Clinical Lung Cancer
Cheng, Haiying H; Hosgood, H Dean HD; Deng, Lei L; Ye, Kenny K; Su, Christopher C; Sharma, Janaki J; Yang, Yuanquan Y; Halmos, Balazs B; Perez-Soler, Roman R
Publication Date: 2020-03

Variant appearance in text: EGFR: P753del
PubMed Link: 31420240
Variant Present in the following documents:
  • Main text
View BVdb publication page



Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.

Nature Communications
Jin, Nan N; Bi, Aiwei A; Lan, Xiaojing X; Xu, Jun J; Wang, Xiaomin X; Liu, Yingluo Y; Wang, Ting T; Tang, Shuai S; Zeng, Hanlin H; Chen, Ziqi Z; Tan, Minjia M; Ai, Jing J; Xie, Hua H; Zhang, Tao T; Liu, Dandan D; Huang, Ruimin R; Song, Yue Y; Leung, Elaine Lai-Han EL; Yao, Xiaojun X; Ding, Jian J; Geng, Meiyu M; Lin, Shu-Hai SH; Huang, Min M
Publication Date: 2019-06-20

Variant appearance in text: EGFR: P753del
PubMed Link: 31221965
Variant Present in the following documents:
  • 41467_2019_10427_MOESM2_ESM.pdf
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Triple Gene Analysis Using Samples Obtained by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration.

Internal Medicine (Tokyo, Japan)
Lee, Kyungjong K; Um, Sang-Won SW; Jeong, Byeong-Ho BH; Yang, Jung Wook JW; Choi, Yoon-La YL; Han, Joungho J; Kim, Hojoong H; Kwon, O Jung OJ
Publication Date: 2016

Variant appearance in text: EGFR: P753del
PubMed Link: 27803402
Variant Present in the following documents:
  • Main text
View BVdb publication page



Comparison of Epidermal Growth Factor Receptor Mutations between Metastatic Lymph Node Diagnosed by EBUS-TBNA and Primary Tumor in Non-Small Cell Lung Cancer.

Plos One
Kang, Hyo Jae HJ; Hwangbo, Bin B; Lee, Jin Soo JS; Kim, Moon Soo MS; Lee, Jong Mog JM; Lee, Geon-Kook GK
Publication Date: 2016

Variant appearance in text: EGFR: P753del
PubMed Link: 27685950
Variant Present in the following documents:
  • Main text
  • pone.0163652.pdf
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Use of dedicated gene panel sequencing using next generation sequencing to improve the personalized care of lung cancer.

Oncotarget
Kaderbhai, Coureche Guillaume CG; Boidot, Romain R; Beltjens, Françoise F; Chevrier, Sandy S; Arnould, Laurent L; Favier, Laure L; Lagrange, Aurélie A; Coudert, Bruno B; Ghiringhelli, François F
Publication Date: 2016-04-26

Variant appearance in text: EGFR: P753del
PubMed Link: 27027238
Variant Present in the following documents:
  • oncotarget-07-24860-s001.pdf
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microRNA classifiers are powerful diagnostic/prognostic tools in ALK-, EGFR-, and KRAS-driven lung cancers.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Gasparini, Pierluigi P; Cascione, Luciano L; Landi, Lorenza L; Carasi, Stefania S; Lovat, Francesca F; Tibaldi, Carmelo C; Alì, Greta G; D'Incecco, Armida A; Minuti, Gabriele G; Chella, Antonio A; Fontanini, Gabriella G; Fassan, Matteo M; Cappuzzo, Federico F; Croce, Carlo M CM
Publication Date: 2015-12-01

Variant appearance in text: EGFR: Pro753del
PubMed Link: 26627242
Variant Present in the following documents:
  • Main text
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Mutational profiling of bone metastases from lung adenocarcinoma: results of a prospective study (POUMOS-TEC).

Bonekey Reports
Confavreux, Cyrille B CB; Girard, Nicolas N; Pialat, Jean-Baptiste JB; Bringuier, Pierre-Paul PP; Devouassoux-Shisheboran, Mojgan M; Rousseau, Jean-Charles JC; Isaac, Sylvie S; Thivolet-Bejui, Françoise F; Clezardin, Philippe P; Brevet, Marie M
Publication Date: 2014

Variant appearance in text: EGFR: P753del
PubMed Link: 25328676
Variant Present in the following documents:
  • Main text
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Identification of candidate genes for lung cancer somatic mutation test kits.

Genetics And Molecular Biology
Chen, Yong Y; Shi, Jian-Xin JX; Pan, Xu-Feng XF; Feng, Jian J; Zhao, Heng H
Publication Date: 2013-09

Variant appearance in text: EGFR: P753del
PubMed Link: 24130455
Variant Present in the following documents:
  • Main text
  • 2013-011.pdf
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Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR.

The Journal Of Molecular Diagnostics : Jmd
Brevet, Marie M; Arcila, Maria M; Ladanyi, Marc M
Publication Date: 2010-03

Variant appearance in text: EGFR: P753del
PubMed Link: 20093391
Variant Present in the following documents:
  • Main text
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Clinical implications of KRAS mutations in lung cancer patients treated with tyrosine kinase inhibitors: an important role for mutations in minor clones.

Neoplasia (New York, N.Y.)
Marchetti, Antonio A; Milella, Michele M; Felicioni, Lara L; Cappuzzo, Federico F; Irtelli, Luciana L; Del Grammastro, Maela M; Sciarrotta, Mariagrazia M; Malatesta, Sara S; Nuzzo, Carmen C; Finocchiaro, Giovanna G; Perrucci, Bruno B; Carlone, Donatella D; Gelibter, Alain J AJ; Ceribelli, Anna A; Mezzetti, Andrea A; Iacobelli, Stefano S; Cognetti, Francesco F; Buttitta, Fiamma F
Publication Date: 2009-10

Variant appearance in text: EGFR: P753del
PubMed Link: 19794967
Variant Present in the following documents:
  • Main text
View BVdb publication page



EGFR and KRAS mutations in patients with adenocarcinoma of the lung.

The Korean Journal Of Internal Medicine
Jang, Tae Won TW; Oak, Chul Ho CH; Chang, Hee Kyung HK; Suo, Soon Jung SJ; Jung, Mann Hong MH
Publication Date: 2009-03

Variant appearance in text: EGFR: P753del
PubMed Link: 19270482
Variant Present in the following documents:
  • Main text
  • kjim-24-48.pdf
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Evaluation of epidermal growth factor receptor mutation status in serum DNA as a predictor of response to gefitinib (IRESSA).

British Journal Of Cancer
Kimura, H H; Suminoe, M M; Kasahara, K K; Sone, T T; Araya, T T; Tamori, S S; Koizumi, F F; Nishio, K K; Miyamoto, K K; Fujimura, M M; Nakao, S S
Publication Date: 2007-09-17

Variant appearance in text: EGFR: P753del
PubMed Link: 17848912
Variant Present in the following documents:
  • Main text
  • 6603949a.pdf
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Mutations in the epidermal growth factor receptor gene are linked to smoking-independent, lung adenocarcinoma.

British Journal Of Cancer
Sonobe, M M; Manabe, T T; Wada, H H; Tanaka, F F
Publication Date: 2005-08-08

Variant appearance in text: EGFR: P753del
PubMed Link: 16052218
Variant Present in the following documents:
  • Main text
  • 93-6602707a.pdf
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