EGFR c.2261A>G ;(p.K754R)

Variant ID: 7-55242491-A-G

NM_005228.3(EGFR):c.2261A>G;(p.K754R)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


JAC4 Inhibits EGFR-Driven Lung Adenocarcinoma Growth and Metastasis through CTBP1-Mediated JWA/AMPK/NEDD4L/EGFR Axis.

International Journal Of Molecular Sciences
Ding, Kun K; Jiang, Xuqian X; Wang, Zhangding Z; Zou, Lu L; Cui, Jiahua J; Li, Xiong X; Shu, Chuanjun C; Li, Aiping A; Zhou, Jianwei J
Publication Date: 2023-05-15

Variant appearance in text: EGFR: K754R
PubMed Link: 37240137
Variant Present in the following documents:
  • Main text
  • ijms-24-08794.pdf
View BVdb publication page



A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.

Cancers
Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC
Publication Date: 2021-07-20

Variant appearance in text: EGFR: K754R
PubMed Link: 34298851
Variant Present in the following documents:
  • Main text
  • cancers-13-03641.pdf
View BVdb publication page



Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer.

Oncology Letters
Quan, Xueping X; Gao, Hongjun H; Wang, Zhikuan Z; Li, Jie J; Zhao, Wentao W; Liang, Wei W; Yu, Qiang Q; Guo, Dongliang D; Hao, Zhanping Z; Liu, Jingxin J
Publication Date: 2018-02

Variant appearance in text: EGFR: K754R
PubMed Link: 29434916
Variant Present in the following documents:
  • Main text
View BVdb publication page



Lung adenocarcinoma patients of young age have lower EGFR mutation rate and poorer efficacy of EGFR tyrosine kinase inhibitors.

Erj Open Research
Wu, Shang-Gin SG; Chang, Yih-Leong YL; Yu, Chong-Jen CJ; Yang, Pan-Chyr PC; Shih, Jin-Yuan JY
Publication Date: 2017-07

Variant appearance in text: EGFR: K754R
PubMed Link: 28717642
Variant Present in the following documents:
  • 00092-2016.pdf
View BVdb publication page



The energy landscape analysis of cancer mutations in protein kinases.

Plos One
Dixit, Anshuman A; Verkhivker, Gennady M GM
Publication Date: 2011

Variant appearance in text: EGFR: K754R
PubMed Link: 21998754
Variant Present in the following documents:
View BVdb publication page