EGFR c.2291A>G ;(p.Y764C)

Variant ID: 7-55248993-A-G

NM_005228.3(EGFR):c.2291A>G;(p.Y764C)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.

Cell Reports. Medicine
Frank, Katrin J KJ; Mulero-Sánchez, Antonio A; Berninger, Alexandra A; Ruiz-Cañas, Laura L; Bosma, Astrid A; Görgülü, Kıvanç K; Wu, Nan N; Diakopoulos, Kalliope N KN; Kaya-Aksoy, Ezgi E; Ruess, Dietrich A DA; Kabacaoğlu, Derya D; Schmidt, Fränze F; Kohlmann, Larissa L; van Tellingen, Olaf O; Thijssen, Bram B; van de Ven, Marieke M; Proost, Natalie N; Kossatz, Susanne S; Weber, Wolfgang A WA; Sainz, Bruno B; Bernards, Rene R; Algül, Hana H; Lesina, Marina M; Mainardi, Sara S
Publication Date: 2022-11-15

Variant appearance in text: EGFR: 2291A>G
PubMed Link: 36384095
Variant Present in the following documents:
  • mmc1.pdf
  • mmc2.pdf
View BVdb publication page



Evaluation of Darolutamide (ODM201) Efficiency on Androgen Receptor Mutants Reported to Date in Prostate Cancer Patients.

Cancers
Lallous, Nada N; Snow, Oliver O; Sanchez, Christophe C; Parra Nuñez, Ana Karla AK; Sun, Bei B; Hussain, Ahmed A; Lee, Joseph J; Morin, Helene H; Leblanc, Eric E; Gleave, Martin E ME; Cherkasov, Artem A
Publication Date: 2021-06-11

Variant appearance in text: EGFR: Y764C
PubMed Link: 34208290
Variant Present in the following documents:
  • Main text
  • cancers-13-02939.pdf
View BVdb publication page



Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.

Communications Biology
Nagasawa, Satoi S; Kuze, Yuta Y; Maeda, Ichiro I; Kojima, Yasuyuki Y; Motoyoshi, Ai A; Onishi, Tatsuya T; Iwatani, Tsuguo T; Yokoe, Takamichi T; Koike, Junki J; Chosokabe, Motohiro M; Kubota, Manabu M; Seino, Hibiki H; Suzuki, Ayako A; Seki, Masahide M; Tsuchihara, Katsuya K; Inoue, Eisuke E; Tsugawa, Koichiro K; Ohta, Tomohiko T; Suzuki, Yutaka Y
Publication Date: 2021-04-01

Variant appearance in text: EGFR: Y764C
PubMed Link: 33795819
Variant Present in the following documents:
  • 42003_2021_1959_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2291A>G; Y764C
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Comprehensive Genomic Profiling of Rare Tumors: Routes to Targeted Therapies.

Frontiers In Oncology
Wang, Shuhang S; Chen, Rongrong R; Tang, Yu Y; Yu, Yue Y; Fang, Yuan Y; Huang, Huiyao H; Wu, Dawei D; Fang, Hong H; Bai, Ying Y; Sun, Chao C; Yu, Anqi A; Fan, Qi Q; Gu, Dejian D; Yi, Xin X; Li, Ning N
Publication Date: 2020

Variant appearance in text: EGFR: 2291A>G; Y764C
PubMed Link: 32373528
Variant Present in the following documents:
  • Table_6.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: Y764C
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page