EGFR c.2296A>G ;(p.M766V)

Variant ID: 7-55248998-A-G

NM_005228.3(EGFR):c.2296A>G;(p.M766V)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


New therapeutic approaches to overcoming resistant EGFR exon 20 alterations.

Critical Reviews In Oncology/Hematology
Li, Alex M AM; Boichard, Amélie A; Felip, Enriqueta E; Kurzrock, Razelle R
Publication Date: 2020-07

Variant appearance in text: EGFR: M766V
PubMed Link: 32485428
Variant Present in the following documents:
  • Main text
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: M766V
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Computational and Experimental Characterization of Patient Derived Mutations Reveal an Unusual Mode of Regulatory Spine Assembly and Drug Sensitivity in EGFR Kinase.

Biochemistry
Ruan, Zheng Z; Katiyar, Samiksha S; Kannan, Natarajan N
Publication Date: 2017-01-10

Variant appearance in text: EGFR: M766V
PubMed Link: 27936599
Variant Present in the following documents:
  • Main text
View BVdb publication page