Variant ID: 7-55249005-G-T

NM_005228.3(EGFR):c.2303G>T;(p.S768I)

This variant was identified in 833 publications

View GRCh38 version.




Publications:


Lung Cancer Biomarker Speak: Teach Me the Language.

Journal Of The Advanced Practitioner In Oncology
Sandy, Beth B; Morrissette, Jennifer J
Publication Date: 2022-04

Variant appearance in text: EGFR: S768I
PubMed Link: 35663172
Variant Present in the following documents:
  • Main text
  • jadpro-13-302.pdf
View BVdb publication page



Leveraging Bulk and Single-Cell RNA Sequencing Data of NSCLC Tumor Microenvironment and Therapeutic Potential of NLOC-15A, A Novel Multi-Target Small Molecule.

Frontiers In Immunology
Lawal, Bashir B; Wu, Alexander T H ATH; Huang, Hsu-Shan HS
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35655775
Variant Present in the following documents:
  • Main text
  • fimmu-13-872470.pdf
View BVdb publication page



Subsequent treatments beyond progression on osimertinib in EGFR-mutated NSCLC and leptomeningeal metastases.

Bmc Medicine
Zheng, Mei-Mei MM; Li, Yang-Si YS; Tu, Hai-Yan HY; Sun, Hao H; Yin, Kai K; Jiang, Ben-Yuan BY; Yang, Jin-Ji JJ; Zhang, Xu-Chao XC; Zhou, Qing Q; Xu, Chong-Rui CR; Wang, Zhen Z; Chen, Hua-Jun HJ; Zhou, De-Xiang DX; Wu, Yi-Long YL
Publication Date: 2022-05-30

Variant appearance in text: EGFR: S768I
PubMed Link: 35644609
Variant Present in the following documents:
  • Main text
  • 12916_2022_Article_2387.pdf
View BVdb publication page



Treatment Strategies for Non-Small Cell Lung Cancer Harboring Common and Uncommon EGFR Mutations: Drug Sensitivity Based on Exon Classification, and Structure-Function Analysis.

Cancers
Kitadai, Rui R; Okuma, Yusuke Y
Publication Date: 2022-05-20

Variant appearance in text: EGFR: S768I
PubMed Link: 35626123
Variant Present in the following documents:
  • Main text
  • cancers-14-02519.pdf
View BVdb publication page



Predicting EGFR mutation, ALK rearrangement, and uncommon EGFR mutation in NSCLC patients by driverless artificial intelligence: a cohort study.

Respiratory Research
Tan, Xueyun X; Li, Yuan Y; Wang, Sufei S; Xia, Hui H; Meng, Rui R; Xu, Juanjuan J; Duan, Yanran Y; Li, Yan Y; Yang, Guanghai G; Ma, Yanling Y; Jin, Yang Y
Publication Date: 2022-05-27

Variant appearance in text: EGFR: S768I
PubMed Link: 35624472
Variant Present in the following documents:
  • Main text
  • 12931_2022_Article_2053.pdf
View BVdb publication page



Genomic Alteration Spectrum of Non-Small Cell Lung Cancer Patients in East-China Characterized by Tumor Tissue DNA and Cell-Free DNA.

Oncotargets And Therapy
Li, Jie J; Chen, Siwen S; Xue, Hui H; Wang, Haoyi H; Huang, Tianwei T; Xie, Hongya H; He, Jiang J; Ke, Cai C; Yu, Zhaonan Z; Ni, Bin B
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35615557
Variant Present in the following documents:
  • Main text
  • ott-15-571.pdf
View BVdb publication page



Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society
Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW
Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2303G>T; Ser768Ile
PubMed Link: 35606799
Variant Present in the following documents:
  • Main text
  • 41021_2022_Article_248.pdf
  • 41021_2022_248_MOESM1_ESM.xlsx
View BVdb publication page



Results of screening in early and advanced thoracic malignancies in the EORTC pan-European SPECTAlung platform.

Scientific Reports
Morfouace, M M; Novello, S S; Stevovic, A A; Dooms, C C; Janžič, U U; Berghmans, T T; Dziadziuszko, R R; Gorlia, T T; Felip, E E; Paz-Ares, L L; Mazieres, J J; O'Brien, M M; Bironzo, P P; Vansteenkiste, J J; Lacroix, L L; Dingemans, A C AC; Golfinopoulos, V V; Besse, B B
Publication Date: 2022-05-18

Variant appearance in text: EGFR: S768I
PubMed Link: 35585228
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_12056.pdf
View BVdb publication page



Afatinib for the Treatment of Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations: An Updated Database of 1023 Cases Brief Report.

Frontiers In Oncology
Yang, James Chih-Hsin JC; Schuler, Martin M; Popat, Sanjay S; Miura, Satoru S; Park, Keunchil K; Passaro, Antonio A; De Marinis, Filippo F; Solca, Flavio F; Märten, Angela A; Kim, Edward S ES
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35574304
Variant Present in the following documents:
  • fonc-12-834704.pdf
View BVdb publication page



Gene profiling of metastatic small intestinal squamous cell carcinoma after lung squamous cell carcinoma surgery: a case report.

Translational Cancer Research
Zhu, Fangchao F; Lin, Jiejun J; Liao, Hongli H; Wang, Yunfei Y; Pan, Jie J
Publication Date: 2022-04

Variant appearance in text: EGFR: 2303G>T; S768I
PubMed Link: 35571658
Variant Present in the following documents:
  • tcr-11-04-967.pdf
View BVdb publication page



CancerVar: An artificial intelligence-empowered platform for clinical interpretation of somatic mutations in cancer.

Science Advances
Li, Quan Q; Ren, Zilin Z; Cao, Kajia K; Li, Marilyn M MM; Wang, Kai K; Zhou, Yunyun Y
Publication Date: 2022-05-06

Variant appearance in text: EGFR: S768I
PubMed Link: 35544644
Variant Present in the following documents:
  • sciadv.abj1624.pdf
View BVdb publication page



The efficacy of T790M mutation testing in liquid biopsy-Real clinic data.

Plos One
Krawczyk, Paweł P; Grzycka-Kowalczyk, Luiza L; Błach, Justyna J; Reszka, Katarzyna K; Chmielewska, Izabela I; Kieszko, Robert R; Wójcik-Superczyńska, Magdalena M; Szczyrek, Michał M; Jankowski, Tomasz T; Milanowski, Janusz J
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35522668
Variant Present in the following documents:
  • pone.0267846.pdf
View BVdb publication page



Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis.

Iscience
Chava, Suresh S; Bugide, Suresh S; Zhang, Xuchen X; Gupta, Romi R; Wajapeyee, Narendra N
Publication Date: 2022-05-20

Variant appearance in text: rs121913465
PubMed Link: 35494243
Variant Present in the following documents:
  • mmc2.xls
View BVdb publication page



Osimertinib-Centered Therapy Against Uncommon Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer- A Mini Review.

Frontiers In Oncology
Song, Chengyang C; Yang, Xueying X
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35494059
Variant Present in the following documents:
  • fonc-12-834585.pdf
View BVdb publication page



Olaparib Combined With Dacomitinib in Osimertinib-Resistant Brain and Leptomeningeal Metastases From Non-Small Cell Lung Cancer: A Case Report and Systematic Review.

Frontiers In Oncology
Zhang, Hui H; Wang, Yong Y; Wu, Huaguo H; Zhou, Shizhen S; Li, Shuo S; Meng, Xiangji X; Tao, Rongjie R; Yu, Jinming J
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35494030
Variant Present in the following documents:
  • fonc-12-877279.pdf
View BVdb publication page



Efficacy of liquid biopsy for disease monitoring and early prediction of tumor progression in EGFR mutation-positive non-small cell lung cancer.

Plos One
Ho, Hsiang-Ling HL; Jiang, Yuqiu Y; Chiang, Chi-Lu CL; Karwowska, Sylwia S; Yerram, Ranga R; Sharma, Keerti K; Scudder, Sidney S; Chiu, Chao-Hua CH; Tsai, Chun-Ming CM; Palma, John F JF; Sharma, Abha A; Chou, Teh-Ying TY
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35482671
Variant Present in the following documents:
  • pone.0267362.pdf
View BVdb publication page



Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Bmc Medical Genomics
Sobahy, Turki M TM; Tashkandi, Ghassan G; Bahussain, Donya D; Al-Harbi, Raneem R
Publication Date: 2022-04-25

Variant appearance in text: EGFR: S768I
PubMed Link: 35468810
Variant Present in the following documents:
  • 12920_2022_1235_MOESM2_ESM.xlsx
View BVdb publication page



Exceptional response to afatinib in a patient with persistent G719A EGFR-mutant NSCLC.

Lung Cancer Management
Kulkarni, Amit A AA; Fujioka, Naomi N; Reinhardt, Lucia L; Patel, Manish R MR; Kratzke, Robert A RA
Publication Date: 2022-03

Variant appearance in text: EGFR: S768I
PubMed Link: 35463918
Variant Present in the following documents:
  • lmt-11-54.pdf
View BVdb publication page



Morphologic-Molecular Transformation of Oncogene Addicted Non-Small Cell Lung Cancer.

International Journal Of Molecular Sciences
Calabrese, Fiorella F; Pezzuto, Federica F; Lunardi, Francesca F; Fortarezza, Francesco F; Tzorakoleftheraki, Sofia-Eleni SE; Resi, Maria Vittoria MV; Tiné, Mariaenrica M; Pasello, Giulia G; Hofman, Paul P
Publication Date: 2022-04-09

Variant appearance in text: EGFR: S768I
PubMed Link: 35456982
Variant Present in the following documents:
  • ijms-23-04164.pdf
View BVdb publication page



Acquired Mechanisms of Resistance to Osimertinib-The Next Challenge.

Cancers
Ríos-Hoyo, Alejandro A; Moliner, Laura L; Arriola, Edurne E
Publication Date: 2022-04-12

Variant appearance in text: EGFR: S768I
PubMed Link: 35454838
Variant Present in the following documents:
  • cancers-14-01931.pdf
View BVdb publication page



The Clinically Actionable Molecular Profile of Early versus Late-Stage Non-Small Cell Lung Cancer, an Individual Age and Sex Propensity-Matched Pair Analysis.

Current Oncology (Toronto, Ont.)
McGuire, Anna L AL; McConechy, Melissa K MK; Melosky, Barb L BL; English, John C JC; Choi, James J JJ; Peng, Defen D; Yee, John J; Furman, Benjamin L S BLS; Aguirre Hernandez, Rosalia R; Feijao, Pedro P; Mulder, David D; Hughesman, Curtis C; Yip, Stephen S
Publication Date: 2022-04-11

Variant appearance in text: EGFR: S768I
PubMed Link: 35448189
Variant Present in the following documents:
  • curroncol-29-00215.pdf
View BVdb publication page



TP53 Co-Mutations in Advanced EGFR-Mutated Non-Small Cell Lung Cancer: Prognosis and Therapeutic Strategy for Cancer Therapy.

Frontiers In Oncology
Liu, Surui S; Yu, Jin J; Zhang, Hui H; Liu, Jie J
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35444951
Variant Present in the following documents:
  • fonc-12-860563.pdf
View BVdb publication page



Chinese Herbal Medicine (Yiqi-Yangyin-Jiedu Decoction) Combined With Osimertinib as First-Line Treatment in EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer (CATLA-2): A Study Protocol for a Double-Blind Randomized Controlled Trial.

Frontiers In Pharmacology
Yao, Jialin J; Lu, Yan Y; Jiao, Lijing L; Bi, Ling L; Yang, Wenxiao W; Su, Lingzi L; Shi, Jun J; Wang, Zhe Z; Gong, Yabin Y; Xu, Ling L
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35431966
Variant Present in the following documents:
  • fphar-13-840889.pdf
View BVdb publication page



EGFR exon 20 insertion mutations in advanced non-small-cell lung cancer: current status and perspectives.

Biomarker Research
Hou, Jiabao J; Li, Hongle H; Ma, Shuxiang S; He, Zhen Z; Yang, Sen S; Hao, Lidan L; Zhou, Hanqiong H; Zhang, Zhe Z; Han, Jing J; Wang, Li L; Wang, Qiming Q
Publication Date: 2022-04-13

Variant appearance in text: EGFR: S768I
PubMed Link: 35418149
Variant Present in the following documents:
  • 40364_2022_Article_372.pdf
View BVdb publication page



Prognostic Value of Albumin-to-Alkaline Phosphatase Ratio for EGFR-Mutated Advanced Non-Small-Cell Lung Cancer Patients Treated with First-Line EGFR-TKIs: A Large Population-Based Study and Literature Review.

International Journal Of General Medicine
Gan, Yuncui Y; Ren, Jing J; Xian, Jinghong J; Yu, He H; Jin, Jing J; Li, Dan D; Li, Weimin W
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35378914
Variant Present in the following documents:
  • ijgm-15-3405.pdf
View BVdb publication page



Overexpression of CEACAM6 activates Src-FAK signaling and inhibits anoikis, through homophilic interactions in lung adenocarcinomas.

Translational Oncology
Kim, Eun Young EY; Cha, Yoon Jin YJ; Jeong, Sukin S; Chang, Yoon Soo YS
Publication Date: 2022-03-28

Variant appearance in text: EGFR: S768I
PubMed Link: 35358791
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Correlation of Epidermal Growth Factor Receptor Mutation With Major Histologic Subtype of Lung Adenocarcinoma According to IASLC/ATS/ERS Classification.

Cancer Control : Journal Of The Moffitt Cancer Center
Boukansa, Sara S; Benbrahim, Zineb Z; Gamrani, Sanaa S; Bardai, Sanae S; Bouguenouch, Laila L; Mazti, Asmae A; Boutahiri, Nadia N; Serraj, Mounia M; Amara, Bouchra B; Ouadnouni, Yassine Y; Smahi, Mohamed M; Alami, Badreeddine B; Mellas, Nawfel N; El Fatemi, Hinde H
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35348028
Variant Present in the following documents:
  • 10.1177_10732748221084930.pdf
View BVdb publication page



Is There a Role for Large Exome Sequencing in the Management of Metastatic Non-Small Cell Lung Cancer: A Brief Report of Real Life.

Frontiers In Oncology
Dalens, Lorraine L; Niogret, Julie J; Kaderbhai, Courèche Guillaume CG; Boidot, Romain R
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35330711
Variant Present in the following documents:
  • fonc-12-863057.pdf
View BVdb publication page



Prognostic Values of Inflammatory Indexes and Clinical Factors in Patients with Epidermal Growth Factor Receptor Mutations in Lung Adenocarcinoma and Treated with Tyrosine Kinase Inhibitors.

Journal Of Personalized Medicine
Chang, Bee-Song BS; Peng, Tai-Chu TC; Wu, Yi-Feng YF; Hsieh, Tsung-Cheng TC; Huang, Chun-Hou CH
Publication Date: 2022-03-05

Variant appearance in text: EGFR: S768I
PubMed Link: 35330404
Variant Present in the following documents:
  • jpm-12-00404.pdf
View BVdb publication page



Effect of Osimertinib on CTCs and ctDNA in EGFR Mutant Non-Small Cell Lung Cancer Patients: The Prognostic Relevance of Liquid Biopsy.

Cancers
Kallergi, Galatea G; Kontopodis, Emmanouil E; Ntzifa, Aliki A; Jordana-Ariza, Núria N; Karachaliou, Niki N; Pantazaka, Evangelia E; Charalambous, Haris A HA; Psyrri, Amanda A; Tsaroucha, Emily E; Boukovinas, Ioannis I; Koumarianou, Anna A; Hatzidaki, Dora D; Lianidou, Evi E; Georgoulias, Vassilis V; Rosell, Rafael R; Kotsakis, Athanasios A
Publication Date: 2022-03-19

Variant appearance in text: EGFR: S768I
PubMed Link: 35326725
Variant Present in the following documents:
  • cancers-14-01574.pdf
View BVdb publication page



Two Unusual Mutations in the Epidermal Growth Factor Receptor Gene in a Patient With Lung Adenocarcinoma.

Cureus
Zapata Laguado, Martin M; Zuluaga, Andrea A; Parra Medina, Rafael R; Bruges, Ricardo R
Publication Date: 2022-02

Variant appearance in text: EGFR: s768i
PubMed Link: 35321064
Variant Present in the following documents:
  • cureus-0014-00000022372.pdf
View BVdb publication page



Efficacy of EGFR-TKI sequential therapy in patients with EGFR exon 19 insertion-positive non-small-cell lung cancer: A case report.

World Journal Of Clinical Cases
Shan, Bin-Bin BB; Li, Yuan Y; Zhao, Chang C; An, Xiao-Qin XQ; Zhang, Quan-Mao QM
Publication Date: 2022-02-26

Variant appearance in text: EGFR: S768I
PubMed Link: 35317151
Variant Present in the following documents:
  • WJCC-10-1883.pdf
View BVdb publication page



PEAC: An Ultrasensitive and Cost-Effective MRD Detection System in Non-small Cell Lung Cancer Using Plasma Specimen.

Frontiers In Medicine
Xu, Jianping J; Pu, Yue Y; Lin, Rui R; Xiao, Shanshan S; Fu, Yingxue Y; Wang, Tao T
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35308511
Variant Present in the following documents:
  • fmed-09-822200.pdf
View BVdb publication page



Rationale and design of a phase II trial of dacomitinib in advanced non-small cell lung cancer patients with uncommon epidermal growth factor receptor mutations: a prospective and single arm study (DANCE study).

Bmc Cancer
Zhang, Bo B; Shi, Chunlei C; Gao, Zhiqiang Z; Zhong, Hua H; Xiong, Liwen L; Gu, Aiqin A; Wang, Weimin W; Chu, Tianqing T; Zhang, Wei W; Wang, Huimin H; Zhang, Xueyan X; Zhong, Runbo R; Han, Baohui B
Publication Date: 2022-03-19

Variant appearance in text: EGFR: S768I
PubMed Link: 35305596
Variant Present in the following documents:
  • 12885_2022_Article_9409.pdf
View BVdb publication page



Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-03-19

Variant appearance in text: EGFR: S768I
PubMed Link: 35304574
Variant Present in the following documents:
  • 41388_2022_Article_2263.pdf
View BVdb publication page



Efficacy of Immune Checkpoint Inhibitors in Patients With EGFR Mutated NSCLC and Potential Risk Factors Associated With Prognosis: A Single Institution Experience.

Frontiers In Immunology
Bai, Menglin M; Wang, Weiqing W; Gao, Xuetian X; Wu, Leilei L; Jin, Peng P; Wu, Hui H; Yu, Jinming J; Meng, Xue X
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35296087
Variant Present in the following documents:
  • fimmu-13-832419.pdf
View BVdb publication page



Case Report: Opportunities and Challenges of Immunotherapy in Heavily-Treated EGFR-Mutant Advanced Squamous Cell Lung Carcinoma After Progression on EGFR-TKIs and Chemotherapy.

Frontiers In Oncology
Jin, Wei W; Wang, Xin X; Wang, Jie J; Lin, Lin L
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35296008
Variant Present in the following documents:
  • fonc-12-820408.pdf
View BVdb publication page



ADAURA: The Splash of Osimertinib in Adjuvant EGFR-Mutant Non-small Cell Lung Cancer.

Oncology And Therapy
Ortega-Franco, Ana A; Rafee, Shereen S
Publication Date: 2022-03-16

Variant appearance in text: EGFR: S768I
PubMed Link: 35294773
Variant Present in the following documents:
  • 40487_2022_Article_190.pdf
View BVdb publication page



Perioperative Circulating Tumor DNA Enables Identification of Patients with Poor Prognosis in Upper Tract Urothelial Carcinoma.

Cancer Science
Nakano, Kosuke K; Koh, Yoko Y; Yamamichi, Gaku G; Yumiba, Satoru S; Tomiyama, Eisuke E; Matsushita, Makoto M; Hayashi, Yujiro Y; Wang, Cong C; Ishizuya, Yu Y; Yamamoto, Yoshiyuki Y; Kato, Taigo T; Hatano, Koji K; Kawashima, Atsunari A; Ujike, Takeshi T; Fujita, Kazutoshi K; Kiyotani, Kazuma K; Katayama, Kotoe K; Yamaguchi, Rui R; Imoto, Seiya S; Imamura, Ryoichi R; Nonomura, Norio N; Uemura, Motohide M
Publication Date: 2022-03-16

Variant appearance in text: EGFR: S768I
PubMed Link: 35293110
Variant Present in the following documents:
  • CAS-113-1830-s004.xlsx
View BVdb publication page



Tyrosine Kinase Inhibitor Activity in Patients with NSCLC Harboring Uncommon EGFR Mutations: A Retrospective International Cohort Study (UpSwinG).

The Oncologist
Popat, Sanjay S; Hsia, Te-Chun TC; Hung, Jen-Yu JY; Jung, Hyun Ae HA; Shih, Jin-Yuan JY; Park, Cheol Kyu CK; Lee, Seung Hyeun SH; Okamoto, Tatsuro T; Ahn, Hee Kyung HK; Lee, Yong Chul YC; Sato, Yuki Y; Lee, Sung Sook SS; Mascaux, Celine C; Daoud, Hasan H; Märten, Angela A; Miura, Satoru S
Publication Date: 2022-03-11

Variant appearance in text: EGFR: S768I
PubMed Link: 35274704
Variant Present in the following documents:
  • oyac022.pdf
View BVdb publication page



The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer.

Frontiers In Oncology
Cai, Jun J; Jiang, Huihui H; Li, Shuqing S; Yan, Xiaoxia X; Wang, Meng M; Li, Na N; Zhu, Cuimin C; Dong, Hui H; Wang, Dongjuan D; Xu, Yue Y; Xie, Hui H; Wu, Shouxin S; Lou, Jingwei J; Zhao, Jiangman J; Li, Qingshan Q
Publication Date: 2021

Variant appearance in text: EGFR: S768I
PubMed Link: 35273907
Variant Present in the following documents:
  • Table_8.xlsx
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2303G>T; S768I
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM7_ESM.xlsx
View BVdb publication page



The Role of TP53 Mutations in EGFR-Mutated Non-Small-Cell Lung Cancer: Clinical Significance and Implications for Therapy.

Cancers
Canale, Matteo M; Andrikou, Kalliopi K; Priano, Ilaria I; Cravero, Paola P; Pasini, Luigi L; Urbini, Milena M; Delmonte, Angelo A; Crinò, Lucio L; Bronte, Giuseppe G; Ulivi, Paola P
Publication Date: 2022-02-23

Variant appearance in text: EGFR: S768I
PubMed Link: 35267450
Variant Present in the following documents:
  • cancers-14-01143.pdf
View BVdb publication page



Various Subtypes of EGFR Mutations in Patients With NSCLC Define Genetic, Immunologic Diversity and Possess Different Prognostic Biomarkers.

Frontiers In Immunology
Lei, Youming Y; Wang, Kun K; Liu, Yinqiang Y; Wang, Xuming X; Xiang, Xudong X; Ning, Xiangu X; Ding, Wanbao W; Duan, Jin J; Li, Dingbiao D; Zhao, Wei W; Li, Yi Y; Zhang, Fujun F; Luo, Xiaoyu X; Shi, Yunfei Y; Wang, Ying Y; Huang, Depei D; Bai, Yuezong Y; Zhang, Hushan H
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35265073
Variant Present in the following documents:
  • fimmu-13-811601.pdf
View BVdb publication page



Development and Validation of a Concise Prediction Scoring System for Asian Lung Cancer Patients with EGFR Mutation Before Treatment.

Technology In Cancer Research & Treatment
An, Wenting W; Fan, Wei W; Zhong, Feiyang F; Wang, Binchen B; Wang, Shan S; Gan, Tian T; Tian, Sufang S; Liao, Meiyan M
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35234540
Variant Present in the following documents:
  • 10.1177_15330338221078732.pdf
View BVdb publication page



Prevalence of Epidermal Growth Factor Receptor Exon 20 Insertion Mutations in Non-small-Cell Lung Cancer in Europe: A Pragmatic Literature Review and Meta-analysis.

Targeted Oncology
Van Sanden, Suzy S; Murton, Molly M; Bobrowska, Anna A; Rahhali, Nora N; Sermon, Jan J; Rodrigues, Bernardo B; Goff-Leggett, Danielle D; Chouaid, Christos C; Sebastian, Martin M; Greystoke, Alastair A
Publication Date: 2022-02-28

Variant appearance in text: EGFR: S768I
PubMed Link: 35226283
Variant Present in the following documents:
  • 11523_2022_Article_868.pdf
View BVdb publication page



Complementing Tissue Testing With Plasma Mutation Profiling Improves Therapeutic Decision-Making for Patients With Lung Cancer.

Frontiers In Medicine
Choudhury, Yukti Y; Tan, Min-Han MH; Shi, Jun Li JL; Tee, Augustine A; Ngeow, Kao Chin KC; Poh, Jonathan J; Goh, Ruth Rosalyn RR; Mong, Jamie J
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35223889
Variant Present in the following documents:
  • fmed-09-758464.pdf
View BVdb publication page



The Lifted Veil of Uncommon EGFR Mutation p.L747P in Non-Small Cell Lung Cancer: Molecular Feature and Targeting Sensitivity to Tyrosine Kinase Inhibitors.

Frontiers In Oncology
Yang, Guangjian G; Liu, Chengming C; Hu, Jiaqi J; Sun, Yang Y; Hu, Peizeng P; Liu, Liu L; Xu, Haiyan H; Li, Dazhou D; Li, Weihua W; Yang, Yaning Y; Sun, Nan N; He, Jie J; Wang, Yan Y
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35223527
Variant Present in the following documents:
  • fonc-12-843299.pdf
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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer
Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J
Publication Date: 2022-02

Variant appearance in text: EGFR: Ser768Ile
PubMed Link: 35221333
Variant Present in the following documents:
  • 43018_2022_332_MOESM3_ESM.xlsx
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Clinical Utility of Plasma Cell-Free DNA EGFR Mutation Analysis in Treatment-Naïve Stage IV Non-Small Cell Lung Cancer Patients.

Journal Of Clinical Medicine
Kim, Bo-Guen BG; Jang, Ja-Hyun JH; Kim, Jong-Won JW; Shin, Sun Hye SH; Jeong, Byeong-Ho BH; Lee, Kyungjong K; Kim, Hojoong H; Kwon, O Jung OJ; Ahn, Myung-Ju MJ; Um, Sang-Won SW
Publication Date: 2022-02-21

Variant appearance in text: EGFR: S768I
PubMed Link: 35207417
Variant Present in the following documents:
  • jcm-11-01144.pdf
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"Real" Tumor-Spread Through Air Spaces of Lung Adenocarcinoma Presented Intrapulmonary Metastases Through Bronchiole Air Spaces: A Case Report.

Jto Clinical And Research Reports
Kaku, Sawako S; Motoi, Noriko N; Watanabe, Hirokazu H; Yoshida, Yukihiro Y; Watanabe, Shun-Ichi SI; Kusumoto, Masahiko M
Publication Date: 2022-02

Variant appearance in text: EGFR: S768I
PubMed Link: 35199051
Variant Present in the following documents:
  • main.pdf
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Clinical outcomes of advanced non-small cell lung cancer patients harboring distinct subtypes of EGFR mutations and receiving first-line tyrosine kinase inhibitors: brain metastasis and de novo T790M matters.

Bmc Cancer
Zeng, Ya Y; Guo, Tiantian T; Zhou, Yue Y; Zhao, Yang Y; Chu, Li L; Chu, Xiao X; Yang, Xi X; Ni, Jianjiao J; Zhu, Zhengfei Z
Publication Date: 2022-02-21

Variant appearance in text: EGFR: S768I
PubMed Link: 35189835
Variant Present in the following documents:
  • 12885_2022_Article_9245.pdf
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Identifying Actionable Variants Using Capture-Based Targeted Sequencing in 563 Patients With Non-Small Cell Lung Carcinoma.

Frontiers In Oncology
Jiang, Haiping H; Wang, Yinan Y; Xu, Hanlin H; Lei, Wei W; Yu, Xiaoyun X; Tian, Haiying H; Meng, Cong C; Wang, Xueying X; Zhao, Zicheng Z; Jin, Xiangfeng X
Publication Date: 2021

Variant appearance in text: EGFR: S768I
PubMed Link: 35186718
Variant Present in the following documents:
  • Table_1.xlsx
  • fonc-11-812433.pdf
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Treatment patterns, testing practices, and outcomes in the pre-FLAURA era for patients with EGFR mutation-positive advanced NSCLC: a retrospective chart review (REFLECT).

Therapeutic Advances In Medical Oncology
Addeo, Alfredo A; Hochmair, Maximilian M; Janzic, Urska U; Dudnik, Elizabeth E; Charpidou, Andriani A; Płużański, Adam A; Ciuleanu, Tudor T; Donev, Ivan Shterev IS; Elbaz, Judith J; Aarøe, Jørgen J; Ott, René R; Peled, Nir N
Publication Date: 2021

Variant appearance in text: EGFR: S768I
PubMed Link: 35173817
Variant Present in the following documents:
  • Main text
  • 10.1177_17588359211059874.pdf
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Identification of Recurrent Insertions and Deletions in Exon 18 and 19 of Human Epidermal Growth Factor Receptor 2 as Potential Drivers in Non-Small-Cell Lung Cancer and Other Cancer Types.

Jco Precision Oncology
Yin, Yan Y; Song, Lijie L; Shi, Dongsheng D; Liu, Bin B; Li, Xiangke X; Yang, Minjie M; Liu, Bihao B; Wang, Dejuan D; Qin, Jianwen J
Publication Date: 2022-02

Variant appearance in text: EGFR: S768I
PubMed Link: 35171661
Variant Present in the following documents:
  • po-6-e2100325.pdf
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Application of CRISPR/Cas9-based mutant enrichment technique to improve the clinical sensitivity of plasma EGFR testing in patients with non-small cell lung cancer.

Cancer Cell International
Kim, Boyeon B; Kim, Yoonjung Y; Shin, Saeam S; Lee, Seung-Tae ST; Cho, Jae Yong JY; Lee, Kyung-A KA
Publication Date: 2022-02-15

Variant appearance in text: EGFR: S768I
PubMed Link: 35168603
Variant Present in the following documents:
  • Main text
  • 12935_2022_Article_2504.pdf
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Osimertinib in advanced EGFR-mutant lung adenocarcinoma with asymptomatic brain metastases: an open-label, 3-arm, phase II pilot study.

Neuro-Oncology Advances
Peled, Nir N; Kian, Waleed W; Inbar, Edna E; Goldstein, Iris M IM; Zemel, Melanie M; Rotem, Ofer O; Rozenblum, Anna B AB; Nechushtan, Hovav H; Dudnik, Elizabeth E; Levin, Daniel D; Zer, Alona A; Keren-Rosenberg, Shoshana S; Yust-Katz, Shlomit S; Fuchs, Vered V; Remilah, Areen A AA; Shelef, Ilan I; Roisman, Laila C LC
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35156036
Variant Present in the following documents:
  • Main text
  • vdab188.pdf
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Co-occurrence CDK4/6 amplification serves as biomarkers of de novo EGFR TKI resistance in sensitizing EGFR mutation non-small cell lung cancer.

Scientific Reports
Sitthideatphaiboon, Piyada P; Teerapakpinyo, Chinachote C; Korphaisarn, Krittiya K; Leelayuwatanakul, Nophol N; Pornpatrananrak, Nopporn N; Poungvarin, Naravat N; Chantranuwat, Poonchavist P; Shuangshoti, Shanop S; Aporntewan, Chatchawit C; Chintanapakdee, Wariya W; Sriuranpong, Virote V; Vinayanuwattikun, Chanida C
Publication Date: 2022-02-09

Variant appearance in text: EGFR: S768I
PubMed Link: 35140316
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_6239.pdf
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The clinicopathological study of lung cancer concealed in end-stage of interstitial lung disease.

Translational Cancer Research
Wang, Bei B; Zhang, Xiaoyan X; Chen, Huang H; Yang, Lei L; Li, Jie J; Xiao, Fei F; Liang, Chaoyang C; Zhong, Dingrong D
Publication Date: 2020-02

Variant appearance in text: EGFR: S768I
PubMed Link: 35117398
Variant Present in the following documents:
  • Main text
  • tcr-09-02-536.pdf
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Histologic transformation of lung adenocarcinoma to squamous cell carcinoma after chemotherapy: two case reports.

Translational Cancer Research
Shao, Yi Y; Zhong, Dian-Sheng DS; Guan, Sha-Sha SS
Publication Date: 2020-01

Variant appearance in text: EGFR: S768I
PubMed Link: 35117193
Variant Present in the following documents:
  • Main text
  • tcr-09-01-388.pdf
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EGFR first- and second-generation TKIs-there is still place for them in EGFR-mutant NSCLC patients.

Translational Cancer Research
Karachaliou, Niki N; Fernandez-Bruno, Manuel M; Bracht, Jillian Wilhelmina Paulina JWP; Rosell, Rafael R
Publication Date: 2019-01

Variant appearance in text: EGFR: S768I
PubMed Link: 35117062
Variant Present in the following documents:
  • Main text
  • tcr-08-S1-S23.pdf
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Analysis of real-word mutations of lung cancer driver genes in five regions of China.

Translational Cancer Research
Sun, Mengyao M; Guo, Ye Y; Shao, Guoguang G; Duan, Xiumei X; Yang, Zhiguang Z; Zhang, Peng P; Liu, Yunpeng Y; Dong, Yutong Y; Wang, Xu X; Xu, Yinghui Y; Sun, Chao C; Ma, Kewei K
Publication Date: 2019-11

Variant appearance in text: EGFR: S768I
PubMed Link: 35117015
Variant Present in the following documents:
  • Main text
  • tcr-08-07-2581.pdf
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Carcinoembryonic antigen in pleural effusion of patients with lung adenocarcinoma: a predictive marker for EGFR mutation.

Translational Cancer Research
Lv, Yan-Ling YL; Liu, Hong-Bing HB; Yuan, Dong-Mei DM; Zhou, Li L; Jin, Shu-Xian SX; Song, Yong Y
Publication Date: 2019-08

Variant appearance in text: EGFR: S768I
PubMed Link: 35116846
Variant Present in the following documents:
  • Main text
  • tcr-08-04-1027.pdf
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Correlation of pulmonary venous circulating tumor cells with clinicopathological parameters in patients with early-stage lung adenocarcinoma.

Translational Cancer Research
Xu, Shi-Bin SB; Xie, Ming-Ran MR; Li, Cai-Wei CW; Wu, Xian-Ning XN; Xu, Mei-Qing MQ
Publication Date: 2019-06

Variant appearance in text: EGFR: S768I
PubMed Link: 35116828
Variant Present in the following documents:
  • Main text
  • tcr-08-03-887.pdf
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Application of liquid biopsy-based targeted capture sequencing analysis to improve the precision treatment of non-small cell lung cancer by tyrosine kinase inhibitors.

Bmj Open Respiratory Research
Zhang, Lei L; Coffin, John J; Formenti, Kim K; Chu, Quincy Q; Izevbaye, Iyare I
Publication Date: 2022-01

Variant appearance in text: EGFR: S768I
PubMed Link: 35091437
Variant Present in the following documents:
  • bmjresp-2021-001154supp001.pdf
  • bmjresp-2021-001154.pdf
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Investigation of PALB2 Mutation and Correlation With Immunotherapy Biomarker in Chinese Non-Small Cell Lung Cancer Patients.

Frontiers In Oncology
Zhang, Jiexia J; Tang, Shuangfeng S; Zhang, Chunning C; Li, Mingyao M; Zheng, Yating Y; Hu, Xue X; Huang, Mengli M; Cheng, Xiangyang X
Publication Date: 2021

Variant appearance in text: EGFR: 2303G>T; S768I
PubMed Link: 35087742
Variant Present in the following documents:
  • Table_2.xlsx
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Lung squamous cell carcinoma with rare epidermal growth factor receptor mutation G719X: a case report and literature review.

Annals Of Translational Medicine
Bi, Huanhuan H; Ren, Dunqiang D; Wu, Jieqiong J; Ding, Xiaoqian X; Guo, Caihong C; Miura, Satoru S; Megyesfalvi, Zsolt Z; Arulananda, Surein S; Wang, Hongmei H
Publication Date: 2021-12

Variant appearance in text: EGFR: S768I
PubMed Link: 35071499
Variant Present in the following documents:
  • Main text
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Real-world experience of afatinib as first-line therapy for advanced EGFR mutation-positive non-small cell lung cancer in Korea.

Translational Lung Cancer Research
Lee, Sung Yong SY; Choi, Chang-Min CM; Chang, Yoon Soo YS; Lee, Kye Young KY; Kim, Seung Joon SJ; Yang, Sei Hoon SH; Ryu, Jeong Seon JS; Lee, Jeong Eun JE; Lee, Shin Yup SY; Park, Ji Young JY; Kim, Young-Chul YC; Oh, In-Jae IJ; Jung, Chi Young CY; Lee, Sang Hoon SH; Yoon, Seong Hoon SH; Choi, Juwhan J; Jang, Tae Won TW
Publication Date: 2021-12

Variant appearance in text: EGFR: S768I
PubMed Link: 35070746
Variant Present in the following documents:
  • Main text
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Prevalence of targeted therapy-related genetic variations in NSCLC and their relationship with clinicopathological characteristics.

Plos One
Li, Fanghua F; Ye, Peng P; Cai, Peiling P; Dong, Dandan D; Zhang, Yihao Y; Yang, Yue Y; Sun, Xingwang X
Publication Date: 2022

Variant appearance in text: EGFR: S768I
PubMed Link: 35061839
Variant Present in the following documents:
  • Main text
  • pone.0262822.pdf
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Use of Circulating Tumour DNA (ctDNA) for Measurement of Therapy Predictive Biomarkers in Patients with Cancer.

Journal Of Personalized Medicine
Duffy, Michael J MJ; Crown, John J
Publication Date: 2022-01-13

Variant appearance in text: EGFR: S768I
PubMed Link: 35055414
Variant Present in the following documents:
  • Main text
  • jpm-12-00099.pdf
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Systemic Inflammation Index and Tumor Glycolytic Heterogeneity Help Risk Stratify Patients with Advanced Epidermal Growth Factor Receptor-Mutated Lung Adenocarcinoma Treated with Tyrosine Kinase Inhibitor Therapy.

Cancers
Lue, Kun-Han KH; Huang, Chun-Hou CH; Hsieh, Tsung-Cheng TC; Liu, Shu-Hsin SH; Wu, Yi-Feng YF; Chen, Yu-Hung YH
Publication Date: 2022-01-08

Variant appearance in text: EGFR: S768I
PubMed Link: 35053473
Variant Present in the following documents:
  • Main text
  • cancers-14-00309.pdf
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Uncommon EGFR Compound Mutations in Non-Small Cell Lung Cancer (NSCLC): A Systematic Review of Available Evidence.

Current Oncology (Toronto, Ont.)
Attili, Ilaria I; Passaro, Antonio A; Pisapia, Pasquale P; Malapelle, Umberto U; de Marinis, Filippo F
Publication Date: 2022-01-09

Variant appearance in text: EGFR: S768I
PubMed Link: 35049698
Variant Present in the following documents:
  • Main text
  • curroncol-29-00024.pdf
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Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics
Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y
Publication Date: 2022-01-15

Variant appearance in text: EGFR: 2303G>T; S768I
PubMed Link: 35031014
Variant Present in the following documents:
  • 12864_2021_8289_MOESM1_ESM.xlsx
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Combined large cell neuroendocrine carcinoma of the lung associated with low-grade fetal adenocarcinoma without β-catenin mutation: a case report.

International Journal Of Clinical And Experimental Pathology
Xiong, Xiaoming X; Ruan, Sibei S; Zhang, Cuiwei C; Xiao, Xiuli X; Long, Hanan H
Publication Date: 2021

Variant appearance in text: EGFR: S768I
PubMed Link: 35027997
Variant Present in the following documents:
  • Main text
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A real-world study of dacomitinib in later-line settings for advanced non-small cell lung cancer patients harboring EGFR mutations.

Cancer Medicine
Li, Hong-Shuai HS; Zhang, Jin-Yao JY; Yan, Xiang X; Xu, Hai-Yan HY; Hao, Xue-Zhi XZ; Xing, Pu-Yuan PY; Wang, Yan Y
Publication Date: 2022-01-12

Variant appearance in text: EGFR: S768I
PubMed Link: 35023313
Variant Present in the following documents:
  • CAM4-11-1026.pdf
View BVdb publication page