Leveraging Bulk and Single-Cell RNA Sequencing Data of NSCLC Tumor Microenvironment and Therapeutic Potential of NLOC-15A, A Novel Multi-Target Small Molecule.
Frontiers In Immunology
Lawal, Bashir B; Wu, Alexander T H ATH; Huang, Hsu-Shan HS
Treatment Strategies for Non-Small Cell Lung Cancer Harboring Common and Uncommon EGFR Mutations: Drug Sensitivity Based on Exon Classification, and Structure-Function Analysis.
Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.
Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society
Results of screening in early and advanced thoracic malignancies in the EORTC pan-European SPECTAlung platform.
Scientific Reports
Morfouace, M M; Novello, S S; Stevovic, A A; Dooms, C C; Janžič, U U; Berghmans, T T; Dziadziuszko, R R; Gorlia, T T; Felip, E E; Paz-Ares, L L; Mazieres, J J; O'Brien, M M; Bironzo, P P; Vansteenkiste, J J; Lacroix, L L; Dingemans, A C AC; Golfinopoulos, V V; Besse, B B
Afatinib for the Treatment of Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations: An Updated Database of 1023 Cases Brief Report.
Frontiers In Oncology
Yang, James Chih-Hsin JC; Schuler, Martin M; Popat, Sanjay S; Miura, Satoru S; Park, Keunchil K; Passaro, Antonio A; De Marinis, Filippo F; Solca, Flavio F; Märten, Angela A; Kim, Edward S ES
The efficacy of T790M mutation testing in liquid biopsy-Real clinic data.
Plos One
Krawczyk, Paweł P; Grzycka-Kowalczyk, Luiza L; Błach, Justyna J; Reszka, Katarzyna K; Chmielewska, Izabela I; Kieszko, Robert R; Wójcik-Superczyńska, Magdalena M; Szczyrek, Michał M; Jankowski, Tomasz T; Milanowski, Janusz J
Olaparib Combined With Dacomitinib in Osimertinib-Resistant Brain and Leptomeningeal Metastases From Non-Small Cell Lung Cancer: A Case Report and Systematic Review.
Morphologic-Molecular Transformation of Oncogene Addicted Non-Small Cell Lung Cancer.
International Journal Of Molecular Sciences
Calabrese, Fiorella F; Pezzuto, Federica F; Lunardi, Francesca F; Fortarezza, Francesco F; Tzorakoleftheraki, Sofia-Eleni SE; Resi, Maria Vittoria MV; Tiné, Mariaenrica M; Pasello, Giulia G; Hofman, Paul P
The Clinically Actionable Molecular Profile of Early versus Late-Stage Non-Small Cell Lung Cancer, an Individual Age and Sex Propensity-Matched Pair Analysis.
Current Oncology (Toronto, Ont.)
McGuire, Anna L AL; McConechy, Melissa K MK; Melosky, Barb L BL; English, John C JC; Choi, James J JJ; Peng, Defen D; Yee, John J; Furman, Benjamin L S BLS; Aguirre Hernandez, Rosalia R; Feijao, Pedro P; Mulder, David D; Hughesman, Curtis C; Yip, Stephen S
Chinese Herbal Medicine (Yiqi-Yangyin-Jiedu Decoction) Combined With Osimertinib as First-Line Treatment in EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer (CATLA-2): A Study Protocol for a Double-Blind Randomized Controlled Trial.
Frontiers In Pharmacology
Yao, Jialin J; Lu, Yan Y; Jiao, Lijing L; Bi, Ling L; Yang, Wenxiao W; Su, Lingzi L; Shi, Jun J; Wang, Zhe Z; Gong, Yabin Y; Xu, Ling L
Prognostic Value of Albumin-to-Alkaline Phosphatase Ratio for EGFR-Mutated Advanced Non-Small-Cell Lung Cancer Patients Treated with First-Line EGFR-TKIs: A Large Population-Based Study and Literature Review.
International Journal Of General Medicine
Gan, Yuncui Y; Ren, Jing J; Xian, Jinghong J; Yu, He H; Jin, Jing J; Li, Dan D; Li, Weimin W
Correlation of Epidermal Growth Factor Receptor Mutation With Major Histologic Subtype of Lung Adenocarcinoma According to IASLC/ATS/ERS Classification.
Cancer Control : Journal Of The Moffitt Cancer Center
Boukansa, Sara S; Benbrahim, Zineb Z; Gamrani, Sanaa S; Bardai, Sanae S; Bouguenouch, Laila L; Mazti, Asmae A; Boutahiri, Nadia N; Serraj, Mounia M; Amara, Bouchra B; Ouadnouni, Yassine Y; Smahi, Mohamed M; Alami, Badreeddine B; Mellas, Nawfel N; El Fatemi, Hinde H
Prognostic Values of Inflammatory Indexes and Clinical Factors in Patients with Epidermal Growth Factor Receptor Mutations in Lung Adenocarcinoma and Treated with Tyrosine Kinase Inhibitors.
Rationale and design of a phase II trial of dacomitinib in advanced non-small cell lung cancer patients with uncommon epidermal growth factor receptor mutations: a prospective and single arm study (DANCE study).
Efficacy of Immune Checkpoint Inhibitors in Patients With EGFR Mutated NSCLC and Potential Risk Factors Associated With Prognosis: A Single Institution Experience.
Case Report: Opportunities and Challenges of Immunotherapy in Heavily-Treated EGFR-Mutant Advanced Squamous Cell Lung Carcinoma After Progression on EGFR-TKIs and Chemotherapy.
The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer.
The Role of TP53 Mutations in EGFR-Mutated Non-Small-Cell Lung Cancer: Clinical Significance and Implications for Therapy.
Cancers
Canale, Matteo M; Andrikou, Kalliopi K; Priano, Ilaria I; Cravero, Paola P; Pasini, Luigi L; Urbini, Milena M; Delmonte, Angelo A; Crinò, Lucio L; Bronte, Giuseppe G; Ulivi, Paola P
Prevalence of Epidermal Growth Factor Receptor Exon 20 Insertion Mutations in Non-small-Cell Lung Cancer in Europe: A Pragmatic Literature Review and Meta-analysis.
Targeted Oncology
Van Sanden, Suzy S; Murton, Molly M; Bobrowska, Anna A; Rahhali, Nora N; Sermon, Jan J; Rodrigues, Bernardo B; Goff-Leggett, Danielle D; Chouaid, Christos C; Sebastian, Martin M; Greystoke, Alastair A
The Lifted Veil of Uncommon EGFR Mutation p.L747P in Non-Small Cell Lung Cancer: Molecular Feature and Targeting Sensitivity to Tyrosine Kinase Inhibitors.
Frontiers In Oncology
Yang, Guangjian G; Liu, Chengming C; Hu, Jiaqi J; Sun, Yang Y; Hu, Peizeng P; Liu, Liu L; Xu, Haiyan H; Li, Dazhou D; Li, Weihua W; Yang, Yaning Y; Sun, Nan N; He, Jie J; Wang, Yan Y
Clinical outcomes of advanced non-small cell lung cancer patients harboring distinct subtypes of EGFR mutations and receiving first-line tyrosine kinase inhibitors: brain metastasis and de novo T790M matters.
Bmc Cancer
Zeng, Ya Y; Guo, Tiantian T; Zhou, Yue Y; Zhao, Yang Y; Chu, Li L; Chu, Xiao X; Yang, Xi X; Ni, Jianjiao J; Zhu, Zhengfei Z
Treatment patterns, testing practices, and outcomes in the pre-FLAURA era for patients with EGFR mutation-positive advanced NSCLC: a retrospective chart review (REFLECT).
Therapeutic Advances In Medical Oncology
Addeo, Alfredo A; Hochmair, Maximilian M; Janzic, Urska U; Dudnik, Elizabeth E; Charpidou, Andriani A; Płużański, Adam A; Ciuleanu, Tudor T; Donev, Ivan Shterev IS; Elbaz, Judith J; Aarøe, Jørgen J; Ott, René R; Peled, Nir N
Identification of Recurrent Insertions and Deletions in Exon 18 and 19 of Human Epidermal Growth Factor Receptor 2 as Potential Drivers in Non-Small-Cell Lung Cancer and Other Cancer Types.
Jco Precision Oncology
Yin, Yan Y; Song, Lijie L; Shi, Dongsheng D; Liu, Bin B; Li, Xiangke X; Yang, Minjie M; Liu, Bihao B; Wang, Dejuan D; Qin, Jianwen J
Application of CRISPR/Cas9-based mutant enrichment technique to improve the clinical sensitivity of plasma EGFR testing in patients with non-small cell lung cancer.
Cancer Cell International
Kim, Boyeon B; Kim, Yoonjung Y; Shin, Saeam S; Lee, Seung-Tae ST; Cho, Jae Yong JY; Lee, Kyung-A KA
Application of liquid biopsy-based targeted capture sequencing analysis to improve the precision treatment of non-small cell lung cancer by tyrosine kinase inhibitors.
Bmj Open Respiratory Research
Zhang, Lei L; Coffin, John J; Formenti, Kim K; Chu, Quincy Q; Izevbaye, Iyare I
Systemic Inflammation Index and Tumor Glycolytic Heterogeneity Help Risk Stratify Patients with Advanced Epidermal Growth Factor Receptor-Mutated Lung Adenocarcinoma Treated with Tyrosine Kinase Inhibitor Therapy.