Publications:

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Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non-small Cell Lung Cancer.

Cancer Research Communications

Frank, Malene S MS; Andersen, Christina S A CSA; Ahlborn, Lise B LB; Pallisgaard, Niels N; Bodtger, Uffe U; Gehl, Julie J

Publication Date: 2022-10

Variant appearance in text: EGFR: 2305G>T; V769L

PubMed Link: 36969747

Variant Present in the following documents:

• crc-22-0258-s07.pdf
• crc-22-0258-s08.xlsx, sheet 1

View BVdb publication page

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Development and validation of a mutation-based model to predict immunotherapeutic efficacy in NSCLC.

Frontiers In Oncology

He, Ping P; Liu, Jie J; Xu, Qingyuan Q; Ma, Huaijun H; Niu, Beifang B; Huang, Gang G; Wu, Wei W

Publication Date: 2023

Variant appearance in text: EGFR: 2305G>T; V769L; rs147149347

PubMed Link: 36910641

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 8

View BVdb publication page

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Pan-cancer clinical impact of latent drivers from double mutations.

Communications Biology

Yavuz, Bengi Ruken BR; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Tuncbag, Nurcan N

Publication Date: 2023-02-20

Variant appearance in text: EGFR: V769L

PubMed Link: 36808143

Variant Present in the following documents:

• 42003_2023_4519_MOESM3_ESM.xlsx, sheet 3

View BVdb publication page

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Mutations in the MET tyrosine kinase domain and resistance to tyrosine kinase inhibitors in non-small-cell lung cancer.

Respiratory Research

Yao, Yu Y; Yang, Huaping H; Zhu, Bo B; Wang, Song S; Pang, Jiaohui J; Wu, Xiaoying X; Xu, Yang Y; Zhang, Junli J; Zhang, Jinfeng J; Ou, Qiuxiang Q; Tian, Hui H; Zhao, Zheng Z

Publication Date: 2023-01-25

Variant appearance in text: EGFR: V769L

PubMed Link: 36698189

Variant Present in the following documents:

• Main text
• 12931_2023_Article_2329.pdf

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs147149347

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 4

View BVdb publication page

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Inconsistent clinical outcomes following afatinib treatment in NSCLC patients harboring uncommon epidermal growth factor receptor mutation.

Frontiers In Oncology

Dong, Wei W; Wang, Congjie C; Wang, Chunsheng C; Zhao, Kewei K; Ma, Zhao Z; Hu, Shanliang S

Publication Date: 2022

Variant appearance in text: EGFR: V769L

PubMed Link: 36425553

Variant Present in the following documents:

• DataSheet_1.pdf

View BVdb publication page

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Multiple mutations in the EGFR gene in lung cancer: a systematic review.

Translational Lung Cancer Research

Castañeda-González, Juan Pablo JP; Chaves, Juan José JJ; Parra-Medina, Rafael R

Publication Date: 2022-10

Variant appearance in text: EGFR: V769L

PubMed Link: 36386461

Variant Present in the following documents:

• Main text
• tlcr-11-10-2148.pdf

View BVdb publication page

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Clinical application of comprehensive genomic profiling panel to thoracic malignancies: A single-center retrospective study.

Thoracic Cancer

Kunimasa, Kei K; Sugimoto, Naotoshi N; Kawamura, Takahisa T; Yamasaki, Tomoyuki T; Honma, Keiichiro K; Nagata, Shigenori S; Kukita, Yoji Y; Fujisawa, Fumie F; Inoue, Tazuko T; Yamaguchi, Yuko Y; Kitasaka, Mitsuko M; Wakamatsu, Toru T; Yamai, Takuo T; Yamamoto, Sachiko S; Hayashi, Takuji T; Inoue, Takako T; Tamiya, Motohiro M; Imamura, Fumio F; Nishimura, Kazuo K; Nishino, Kazumi K

Publication Date: 2022-11

Variant appearance in text: EGFR: V769L

PubMed Link: 36100256

Variant Present in the following documents:

• TCA-13-2970.pdf

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: EGFR: 2305G>T; V769L

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW

Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2305G>T; Val769Leu

PubMed Link: 35606799

Variant Present in the following documents:

• 41021_2022_248_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Is There a Role for Large Exome Sequencing in the Management of Metastatic Non-Small Cell Lung Cancer: A Brief Report of Real Life.

Frontiers In Oncology

Dalens, Lorraine L; Niogret, Julie J; Kaderbhai, Courèche Guillaume CG; Boidot, Romain R

Publication Date: 2022

Variant appearance in text: EGFR: V769L

PubMed Link: 35330711

Variant Present in the following documents:

• Main text
• fonc-12-863057.pdf

View BVdb publication page

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: V769L

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2305G>T; V769L

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Co-occurrence CDK4/6 amplification serves as biomarkers of de novo EGFR TKI resistance in sensitizing EGFR mutation non-small cell lung cancer.

Scientific Reports

Sitthideatphaiboon, Piyada P; Teerapakpinyo, Chinachote C; Korphaisarn, Krittiya K; Leelayuwatanakul, Nophol N; Pornpatrananrak, Nopporn N; Poungvarin, Naravat N; Chantranuwat, Poonchavist P; Shuangshoti, Shanop S; Aporntewan, Chatchawit C; Chintanapakdee, Wariya W; Sriuranpong, Virote V; Vinayanuwattikun, Chanida C

Publication Date: 2022-02-09

Variant appearance in text: EGFR: V769L

PubMed Link: 35140316

Variant Present in the following documents:

• 41598_2022_6239_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Co-occurrence CDK4/6 amplification serves as biomarkers of de novo EGFR TKI resistance in sensitizing EGFR mutation non-small cell lung cancer.

Scientific Reports

Sitthideatphaiboon, Piyada P; Teerapakpinyo, Chinachote C; Korphaisarn, Krittiya K; Leelayuwatanakul, Nophol N; Pornpatrananrak, Nopporn N; Poungvarin, Naravat N; Chantranuwat, Poonchavist P; Shuangshoti, Shanop S; Aporntewan, Chatchawit C; Chintanapakdee, Wariya W; Sriuranpong, Virote V; Vinayanuwattikun, Chanida C

Publication Date: 2022-02-09

Variant appearance in text: EGFR: V769L

PubMed Link: 35140316

Variant Present in the following documents:

• 41598_2022_6239_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Utilizing phenotypic characteristics of metastatic brain tumors to improve the probability of detecting circulating tumor DNA from cerebrospinal fluid in non-small-cell lung cancer patients: development and validation of a prediction model in a prospective cohort study.

Esmo Open

Li, M M; Hou, X X; Zheng, L L; Ma, Y Y; Li, D D; Lv, Y Y; Chen, J J; Zheng, W W; Shao, Y Y; Mou, Y Y; Chen, L L

Publication Date: 2022-02

Variant appearance in text: EGFR: V769L

PubMed Link: 34922300

Variant Present in the following documents:

• mmc1.xlsx, sheet 1

View BVdb publication page

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Molecular Mechanism of EGFR-TKI Resistance in EGFR-Mutated Non-Small Cell Lung Cancer: Application to Biological Diagnostic and Monitoring.

Cancers

Reita, Damien D; Pabst, Lucile L; Pencreach, Erwan E; Guérin, Eric E; Dano, Laurent L; Rimelen, Valérie V; Voegeli, Anne-Claire AC; Vallat, Laurent L; Mascaux, Céline C; Beau-Faller, Michèle M

Publication Date: 2021-09-30

Variant appearance in text: EGFR: V769L

PubMed Link: 34638411

Variant Present in the following documents:

• Main text

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Val769Leu

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Val769Leu

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer

Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J

Publication Date: 2021-11

Variant appearance in text: EGFR: V769L

PubMed Link: 34549528

Variant Present in the following documents:

• Main text
• TCA-12-2924.pdf

View BVdb publication page

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Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer

Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J

Publication Date: 2021-11

Variant appearance in text: EGFR: V769L

PubMed Link: 34549528

Variant Present in the following documents:

• Main text
• TCA-12-2924.pdf

View BVdb publication page

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Structure-based classification predicts drug response in EGFR-mutant NSCLC.

Nature

Robichaux, Jacqulyne P JP; Le, Xiuning X; Vijayan, R S K RSK; Hicks, J Kevin JK; Heeke, Simon S; Elamin, Yasir Y YY; Lin, Heather Y HY; Udagawa, Hibiki H; Skoulidis, Ferdinandos F; Tran, Hai H; Varghese, Susan S; He, Junqin J; Zhang, Fahao F; Nilsson, Monique B MB; Hu, Lemei L; Poteete, Alissa A; Rinsurongkawong, Waree W; Zhang, Xiaoshan X; Ren, Chenghui C; Liu, Xiaoke X; Hong, Lingzhi L; Zhang, Jianjun J; Diao, Lixia L; Madison, Russell R; Schrock, Alexa B AB; Saam, Jennifer J; Raymond, Victoria V; Fang, Bingliang B; Wang, Jing J; Ha, Min Jin MJ; Cross, Jason B JB; Gray, Jhanelle E JE; Heymach, John V JV

Publication Date: 2021-09

Variant appearance in text: EGFR: 2305G>T; V769L

PubMed Link: 34526717

Variant Present in the following documents:

• 41586_2021_3898_MOESM1_ESM.pdf
• 41586_2021_Article_3898.pdf

View BVdb publication page

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A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.

Cancers

Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC

Publication Date: 2021-07-20

Variant appearance in text: EGFR: V769L

PubMed Link: 34298851

Variant Present in the following documents:

• Main text

View BVdb publication page

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Longitudinal Circulating Tumor DNA Analysis in Blood and Saliva for Prediction of Response to Osimertinib and Disease Progression in EGFR-Mutant Lung Adenocarcinoma.

Cancers

Kim, Chul C; Xi, Liqiang L; Cultraro, Constance M CM; Wei, Fang F; Jones, Gregory G; Cheng, Jordan J; Shafiei, Ahmad A; Pham, Trinh Hoc-Tran TH; Roper, Nitin N; Akoth, Elizabeth E; Ghafoor, Azam A; Misra, Vikram V; Monkash, Nina N; Strom, Charles C; Tu, Michael M; Liao, Wei W; Chia, David D; Morris, Clive C; Steinberg, Seth M SM; Bagheri, Hadi H; Wong, David T W DTW; Raffeld, Mark M; Guha, Udayan U

Publication Date: 2021-07-03

Variant appearance in text: EGFR: V769L

PubMed Link: 34283064

Variant Present in the following documents:

• cancers-13-03342.pdf

View BVdb publication page

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EGFR-Mutated Squamous Cell Lung Cancer and Its Association With Outcomes.

Frontiers In Oncology

Jin, Rui R; Peng, Ling L; Shou, Jiawei J; Wang, Jin J; Jin, Yin Y; Liang, Fei F; Zhao, Jing J; Wu, Mengmeng M; Li, Qin Q; Zhang, Bin B; Wu, Xiaoying X; Lan, Fen F; Xia, Lixia L; Yan, Junrong J; Shao, Yang Y; Stebbing, Justin J; Shen, Huahao H; Li, Wen W; Xia, Yang Y

Publication Date: 2021

Variant appearance in text: EGFR: 2305G>T; V769L

PubMed Link: 34195081

Variant Present in the following documents:

• Table_2.xlsx, sheet 2

View BVdb publication page

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Improvement of Neoantigen Identification Through Convolution Neural Network.

Frontiers In Immunology

Hao, Qing Q; Wei, Ping P; Shu, Yang Y; Zhang, Yi-Guan YG; Xu, Heng H; Zhao, Jun-Ning JN

Publication Date: 2021

Variant appearance in text: EGFR: V769L

PubMed Link: 34113354

Variant Present in the following documents:

• Table_1.xlsx, sheet 17

View BVdb publication page

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Mutated circulating tumor DNA as a liquid biopsy in lung cancer detection and treatment.

Molecular Oncology

Filipska, Martyna M; Rosell, Rafael R

Publication Date: 2021-06

Variant appearance in text: EGFR: V769L

PubMed Link: 33969622

Variant Present in the following documents:

• Main text

View BVdb publication page

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Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications

Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L

Publication Date: 2021-04-19

Variant appearance in text: EGFR: V769L

PubMed Link: 33875650

Variant Present in the following documents:

• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1
• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 5

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: EGFR: 2305G>T; V769L

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Combined assay of Circulating Tumor DNA and Protein Biomarkers for early noninvasive detection and prognosis of Non-Small Cell Lung Cancer.

Journal Of Cancer

Yin, Jian-Xin JX; Hu, Wen-Wei WW; Gu, Hua H; Fang, Jian-Min JM

Publication Date: 2021

Variant appearance in text: EGFR: V769L

PubMed Link: 33442424

Variant Present in the following documents:

• Main text
• jcav12p1258s2.xlsx, sheet 4
• jcav12p1258.pdf

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2305G>T; V769L

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports

Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O

Publication Date: 2020-10-13

Variant appearance in text: rs147149347

PubMed Link: 33051506

Variant Present in the following documents:

• 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Deep phylogeny of cancer drivers and compensatory mutations.

Communications Biology

Rochman, Nash D ND; Wolf, Yuri I YI; Koonin, Eugene V EV

Publication Date: 2020-10-02

Variant appearance in text: EGFR: V769L

PubMed Link: 33009502

Variant Present in the following documents:

• 42003_2020_1276_MOESM11_ESM.xlsx, sheet 1

View BVdb publication page

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Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications

Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG

Publication Date: 2020-07-30

Variant appearance in text: EGFR: V769L

PubMed Link: 32732999

Variant Present in the following documents:

• 41467_2020_17659_MOESM3_ESM.xls, sheet 1

View BVdb publication page

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Liquid biopsy mutation panel for non-small cell lung cancer: analytical validation and clinical concordance.

Npj Precision Oncology

Schwartzberg, Lee S LS; Horinouchi, Hidehito H; Chan, David D; Chernilo, Sara S; Tsai, Michaela L ML; Isla, Dolores D; Escriu, Carles C; Bennett, John P JP; Clark-Langone, Kim K; Svedman, Christer C; Tomasini, Pascale P; ,

Publication Date: 2020

Variant appearance in text: EGFR: V769L

PubMed Link: 32596507

Variant Present in the following documents:

• Main text
• 41698_2020_118_MOESM1_ESM.pdf
• 41698_2020_Article_118.pdf

View BVdb publication page

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EGFR mutation status in a series of Turkish non-small cell lung cancer patients.

Biomedical Reports

Calibasi-Kocal, Gizem G; Amirfallah, Arsalan A; Sever, Tolga T; Umit Unal, Olcun O; Gurel, Duygu D; Oztop, Ilhan I; Ellidokuz, Hulya H; Basbinar, Yasemin Y

Publication Date: 2020-08

Variant appearance in text: EGFR: Val769Leu

PubMed Link: 32509305

Variant Present in the following documents:

• Main text

View BVdb publication page

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New therapeutic approaches to overcoming resistant EGFR exon 20 alterations.

Critical Reviews In Oncology/Hematology

Li, Alex M AM; Boichard, Amélie A; Felip, Enriqueta E; Kurzrock, Razelle R

Publication Date: 2020-07

Variant appearance in text: EGFR: V769L

PubMed Link: 32485428

Variant Present in the following documents:

• Main text

View BVdb publication page

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Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer.

Cell Reports. Medicine

Roper, Nitin N; Brown, Anna-Leigh AL; Wei, Jun S JS; Pack, Svetlana S; Trindade, Christopher C; Kim, Chul C; Restifo, Olivia O; Gao, Shaojian S; Sindiri, Sivasish S; Mehrabadi, Farid F; El Meskini, Rajaa R; Ohler, Zoe Weaver ZW; Maity, Tapan K TK; Venugopalan, Abhilash A; Cultraro, Constance M CM; Akoth, Elizabeth E; Padiernos, Emerson E; Chen, Haobin H; Kesarwala, Aparna A; Smart, DeeDee K DK; Nilubol, Naris N; Rajan, Arun A; Piotrowska, Zofia Z; Xi, Liqiang L; Raffeld, Mark M; Panchenko, Anna R AR; Sahinalp, Cenk C; Hewitt, Stephen S; Hoang, Chuong D CD; Khan, Javed J; Guha, Udayan U

Publication Date: 2020-04-21

Variant appearance in text: EGFR: V769L

PubMed Link: 32483558

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

View BVdb publication page

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Spectrum of EGFR aberrations and potential clinical implications: insights from integrative pan-cancer analysis.

Cancer Communications (London, England)

Liu, Haijing H; Zhang, Bo B; Sun, Zhifu Z

Publication Date: 2020-01

Variant appearance in text: EGFR: V769L

PubMed Link: 32067422

Variant Present in the following documents:

• CAC2-40-43-s001.xlsx, sheet 1

View BVdb publication page

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Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in EGFR-Mutant Lung Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Schoenfeld, Adam J AJ; Chan, Joseph M JM; Kubota, Daisuke D; Sato, Hiroki H; Rizvi, Hira H; Daneshbod, Yahya Y; Chang, Jason C JC; Paik, Paul K PK; Offin, Michael M; Arcila, Maria E ME; Davare, Monika A MA; Shinde, Ujwal U; Pe'er, Dana D; Rekhtman, Natasha N; Kris, Mark G MG; Somwar, Romel R; Riely, Gregory J GJ; Ladanyi, Marc M; Yu, Helena A HA

Publication Date: 2020-06-01

Variant appearance in text: EGFR: V769L

PubMed Link: 31911548

Variant Present in the following documents:

• Main text

View BVdb publication page

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Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer.

Seminars In Cancer Biology

Harrison, Peter T PT; Vyse, Simon S; Huang, Paul H PH

Publication Date: 2020-04

Variant appearance in text: EGFR: V769L

PubMed Link: 31562956

Variant Present in the following documents:

• main.pdf

View BVdb publication page

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miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma.

Nature Metabolism

Zhang, Wen Cai WC; Wells, Julie M JM; Chow, Kin-Hoe KH; Huang, He H; Yuan, Min M; Saxena, Tanvi T; Melnick, Mary Ann MA; Politi, Katerina K; Asara, John M JM; Costa, Daniel B DB; Bult, Carol J CJ; Slack, Frank J FJ

Publication Date: 2019-04

Variant appearance in text: EGFR: 2305G>T; V769L

PubMed Link: 31535082

Variant Present in the following documents:

• NIHMS1523414-supplement-Sup_Tables.xlsx, sheet 7

View BVdb publication page

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Survival Disparities in Black Patients With EGFR-mutated Non-small-cell Lung Cancer.

Clinical Lung Cancer

Cheng, Haiying H; Hosgood, H Dean HD; Deng, Lei L; Ye, Kenny K; Su, Christopher C; Sharma, Janaki J; Yang, Yuanquan Y; Halmos, Balazs B; Perez-Soler, Roman R

Publication Date: 2020-03

Variant appearance in text: EGFR: V769L

PubMed Link: 31420240

Variant Present in the following documents:

• Main text

View BVdb publication page

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Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Ikemura, Shinnosuke S; Yasuda, Hiroyuki H; Matsumoto, Shingo S; Kamada, Mayumi M; Hamamoto, Junko J; Masuzawa, Keita K; Kobayashi, Keigo K; Manabe, Tadashi T; Arai, Daisuke D; Nakachi, Ichiro I; Kawada, Ichiro I; Ishioka, Kota K; Nakamura, Morio M; Namkoong, Ho H; Naoki, Katsuhiko K; Ono, Fumie F; Araki, Mitsugu M; Kanada, Ryo R; Ma, Biao B; Hayashi, Yuichiro Y; Mimaki, Sachiyo S; Yoh, Kiyotaka K; Kobayashi, Susumu S SS; Kohno, Takashi T; Okuno, Yasushi Y; Goto, Koichi K; Tsuchihara, Katsuya K; Soejima, Kenzo K

Publication Date: 2019-05-14

Variant appearance in text: EGFR: V769L

PubMed Link: 31043566

Variant Present in the following documents:

• pnas.1819430116.sapp.pdf

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: EGFR: V769L

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

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Molecular designing, virtual screening and docking study of novel curcumin analogue as mutation (S769L and K846R) selective inhibitor for EGFR.

Saudi Journal Of Biological Sciences

Shaik, Noor Ahmad NA; Al-Kreathy, Huda M HM; Ajabnoor, Ghada M GM; Verma, Prashant Kumar PK; Banaganapalli, Babajan B

Publication Date: 2019-03

Variant appearance in text: EGFR: V769L

PubMed Link: 30899155

Variant Present in the following documents:

• Main text
• main.pdf

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MHC class II restricted neoantigen peptides predicted by clonal mutation analysis in lung adenocarcinoma patients: implications on prognostic immunological biomarker and vaccine design.

Bmc Genomics

Cai, Weijing W; Zhou, Dapeng D; Wu, Weibo W; Tan, Wen Ling WL; Wang, Jiaqian J; Zhou, Caicun C; Lou, Yanyan Y

Publication Date: 2018-08-03

Variant appearance in text: EGFR: V769L

PubMed Link: 30075702

Variant Present in the following documents:

• 12864_2018_4958_MOESM5_ESM.xlsx, sheet 1
• 12864_2018_4958_MOESM4_ESM.xlsx, sheet 1
• 12864_2018_4958_MOESM3_ESM.xlsx, sheet 1

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Integrative omics analyses broaden treatment targets in human cancer.

Genome Medicine

Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L

Publication Date: 2018-07-27

Variant appearance in text: EGFR: V769L

PubMed Link: 30053901

Variant Present in the following documents:

• 13073_2018_564_MOESM2_ESM.xlsx, sheet 10
• 13073_2018_564_MOESM2_ESM.xlsx, sheet 19
• 13073_2018_564_MOESM2_ESM.xlsx, sheet 13
• 13073_2018_564_MOESM2_ESM.xlsx, sheet 8

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Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer.

Therapeutic Advances In Medical Oncology

Elster, Naomi N; Toomey, Sinead S; Fan, Yue Y; Cremona, Mattia M; Morgan, Clare C; Weiner Gorzel, Karolina K; Bhreathnach, Una U; Milewska, Malgorzata M; Murphy, Madeline M; Madden, Stephen S; Naidoo, Jarushka J; Fay, Joanna J; Kay, Elaine E; Carr, Aoife A; Kennedy, Sean S; Furney, Simon S; Mezynski, Janusz J; Breathhnach, Oscar O; Morris, Patrick P; Grogan, Liam L; Hill, Arnold A; Kennedy, Susan S; Crown, John J; Gallagher, William W; Hennessy, Bryan B; Eustace, Alex A

Publication Date: 2018

Variant appearance in text: EGFR: V769L

PubMed Link: 30023006

Variant Present in the following documents:

• Main text
• 10.1177_1758835918778297.pdf

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Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.

Cancer Cell

Hellmann, Matthew D MD; Nathanson, Tavi T; Rizvi, Hira H; Creelan, Benjamin C BC; Sanchez-Vega, Francisco F; Ahuja, Arun A; Ni, Ai A; Novik, Jacki B JB; Mangarin, Levi M B LMB; Abu-Akeel, Mohsen M; Liu, Cailian C; Sauter, Jennifer L JL; Rekhtman, Natasha N; Chang, Eliza E; Callahan, Margaret K MK; Chaft, Jamie E JE; Voss, Martin H MH; Tenet, Megan M; Li, Xue-Mei XM; Covello, Kelly K; Renninger, Andrea A; Vitazka, Patrik P; Geese, William J WJ; Borghaei, Hossein H; Rudin, Charles M CM; Antonia, Scott J SJ; Swanton, Charles C; Hammerbacher, Jeff J; Merghoub, Taha T; McGranahan, Nicholas N; Snyder, Alexandra A; Wolchok, Jedd D JD

Publication Date: 2018-05-14

Variant appearance in text: EGFR: V769L

PubMed Link: 29657128

Variant Present in the following documents:

• mmc3.xlsx, sheet 3

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Molecular Screening of Small Biopsy Samples Using Next-Generation Sequencing in Korean Patients with Advanced Non-small Cell Lung Cancer: Korean Lung Cancer Consortium (KLCC-13-01).

Journal Of Pathology And Translational Medicine

Ku, Bo Mi BM; Heo, Mi Hwa MH; Kim, Joo-Hang JH; Cho, Byoung Chul BC; Cho, Eun Kyung EK; Min, Young Joo YJ; Lee, Ki Hyeong KH; Sun, Jong-Mu JM; Lee, Se-Hoon SH; Ahn, Jin Seok JS; Park, Keunchil K; Kim, Tae Jung TJ; Lee, Ho Yun HY; Kim, Hojoong H; Lee, Kyung-Jong KJ; Ahn, Myung-Ju MJ

Publication Date: 2018-05

Variant appearance in text: EGFR: V769L

PubMed Link: 29575851

Variant Present in the following documents:

• Main text

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Genomic alterations of ERBB receptors in cancer: clinical implications.

Oncotarget

Mishra, Rosalin R; Hanker, Ariella B AB; Garrett, Joan T JT

Publication Date: 2017-12-26

Variant appearance in text: EGFR: V769L

PubMed Link: 29371993

Variant Present in the following documents:

• Main text
• oncotarget-08-114371.pdf

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: EGFR: V769L; rs147149347

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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Clinical value of the new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification of lung adenocarcinoma.

Thoracic Cancer

Guo, Ziwei Z; Yi, Fumei F; Yin, Wencheng W; Zhang, Yu Y; Li, Qian Q; Gu, Yangchun Y; Xiao, Yu Y; Cao, Baoshan B; Ma, Liwen L; Liang, Li L

Publication Date: 2017-05

Variant appearance in text: EGFR: V769L

PubMed Link: 28220630

Variant Present in the following documents:

• Main text

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Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations.

Jama Oncology

Campbell, Joshua D JD; Lathan, Christopher C; Sholl, Lynette L; Ducar, Matthew M; Vega, Mikenah M; Sunkavalli, Ashwini A; Lin, Ling L; Hanna, Megan M; Schubert, Laura L; Thorner, Aaron A; Faris, Nicholas N; Williams, David R DR; Osarogiagbon, Raymond U RU; van Hummelen, Paul P; Meyerson, Matthew M; MacConaill, Laura L

Publication Date: 2017-06-01

Variant appearance in text: EGFR: V769L

PubMed Link: 28114446

Variant Present in the following documents:

• Main text

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Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment.

British Journal Of Cancer

Kuiper, J L JL; Hashemi, S M S SM; Thunnissen, E E; Snijders, P J F PJ; Grünberg, K K; Bloemena, E E; Sie, D D; Postmus, P E PE; Heideman, D A M DA; Smit, E F EF

Publication Date: 2016-12-06

Variant appearance in text: EGFR: V769L

PubMed Link: 27875527

Variant Present in the following documents:

• bjc2016372a.pdf

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DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties.

Oncogenesis

Little, A C AC; Sham, D D; Hristova, M M; Danyal, K K; Heppner, D E DE; Bauer, R A RA; Sipsey, L M LM; Habibovic, A A; van der Vliet, A A

Publication Date: 2016-10-03

Variant appearance in text: EGFR: V769L

PubMed Link: 27694834

Variant Present in the following documents:

• Main text
• oncsis201661a.pdf

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Not all epidermal growth factor receptor mutations in lung cancer are created equal: Perspectives for individualized treatment strategy.

Cancer Science

Kobayashi, Yoshihisa Y; Mitsudomi, Tetsuya T

Publication Date: 2016-09

Variant appearance in text: EGFR: V769L

PubMed Link: 27323238

Variant Present in the following documents:

• CAS-107-1179.pdf

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Heterogeneity of resistance mutations detectable by nextgeneration sequencing in TKI-treated lung adenocarcinoma.

Oncotarget

Belchis, Deborah A DA; Tseng, Li-Hui LH; Gniadek, Thomas T; Haley, Lisa L; Lokhandwala, Parvez P; Illei, Peter P; Gocke, Christopher D CD; Forde, Patrick P; Brahmer, Julie J; Askin, Frederic B FB; Eshleman, James R JR; Lin, Ming-Tseh MT

Publication Date: 2016-07-19

Variant appearance in text: EGFR: V769L

PubMed Link: 27304188

Variant Present in the following documents:

• Main text

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VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research.

Nucleic Acids Research

Lai, Zhongwu Z; Markovets, Aleksandra A; Ahdesmaki, Miika M; Chapman, Brad B; Hofmann, Oliver O; McEwen, Robert R; Johnson, Justin J; Dougherty, Brian B; Barrett, J Carl JC; Dry, Jonathan R JR

Publication Date: 2016-06-20

Variant appearance in text: EGFR: 2305G>T; V769L; rs147149347

PubMed Link: 27060149

Variant Present in the following documents:

• supp_gkw227_nar-03544-met-k-2015-File003.xls, sheet 2

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