EGFR c.2309A>C ;(p.D770A)

Variant ID: 7-55249011-A-C

NM_005228.3(EGFR):c.2309A>C;(p.D770A)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications
Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI
Publication Date: 2023-02-08

Variant appearance in text: EGFR: D770A
PubMed Link: 36755027
Variant Present in the following documents:
  • 41467_2023_36328_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Tackling Drug Resistance in EGFR Exon 20 Insertion Mutant Lung Cancer.

Pharmacogenomics And Personalized Medicine
Pacini, Laura L; Jenks, Andrew D AD; Vyse, Simon S; Wilding, Christopher P CP; Arthur, Amani A; Huang, Paul H PH
Publication Date: 2021

Variant appearance in text: EGFR: D770A
PubMed Link: 33727854
Variant Present in the following documents:
  • Main text
  • pgpm-14-301.pdf
View BVdb publication page



Genomic profiling of lung adenocarcinoma patients reveals therapeutic targets and confers clinical benefit when standard molecular testing is negative.

Oncotarget
Lim, Sun Min SM; Kim, Eun Young EY; Kim, Hye Ryun HR; Ali, Siraj M SM; Greenbowe, Joel R JR; Shim, Hyo Sup HS; Chang, Hyun H; Lim, Seungtaek S; Paik, Soonmyung S; Cho, Byoung Chul BC
Publication Date: 2016-04-26

Variant appearance in text: EGFR: D770A
PubMed Link: 26992220
Variant Present in the following documents:
  • Main text
  • oncotarget-07-24172.pdf
View BVdb publication page



Destabilization of the epidermal growth factor receptor (EGFR) by a peptide that inhibits EGFR binding to heat shock protein 90 and receptor dimerization.

The Journal Of Biological Chemistry
Ahsan, Aarif A; Ray, Dipankar D; Ramanand, Susmita G SG; Hegde, Ashok A; Whitehead, Christopher C; Rehemtulla, Alnawaz A; Morishima, Yoshihiro Y; Pratt, William B WB; Osawa, Yoichi Y; Lawrence, Theodore S TS; Nyati, Mukesh K MK
Publication Date: 2013-09-13

Variant appearance in text: EGFR: D770A
PubMed Link: 23897823
Variant Present in the following documents:
  • Main text
View BVdb publication page