EGFR c.2310_2311insGGG ;(p.D770

EGFR c.2310_2311insGGG ;(p.D770_N771insG)

Variant ID: 7-55249012-C-CGGG

NM_005228.3(EGFR):c.2310_2311insGGG;(p.D770_N771insG)

This variant was identified in 8 publications

View GRCh38 version.

Variant-Specific Resource Links:

gnomAD v2.1.1

Mutalizer Name Checker

Google

UCSC Genome Browser

ClinVar

dbSNP

Publications:

Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications

Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI

Publication Date: 2023-02-08

Variant appearance in text: EGFR: 2310_2311insGGG; D770_N771insG

PubMed Link: 36755027

Variant Present in the following documents:

41467_2023_36328_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: EGFR: 2310_2311insGGG; D770_N771insG

PubMed Link: 35814426

Variant Present in the following documents:

DataSheet_1.xlsx, sheet 2

View BVdb publication page

Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW

Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2310_2311insGGG; Asp770_Asn771insGly

PubMed Link: 35606799

Variant Present in the following documents:

41021_2022_248_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2310_2311insGGG; D770_N771insG

PubMed Link: 35273153

Variant Present in the following documents:

41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: EGFR: 2310_2311insGGG; Asp770_Asn771insGly

PubMed Link: 35031014

Variant Present in the following documents:

12864_2021_8289_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: EGFR: 2310_2311insGGG; Asp770_Asn771insGly

PubMed Link: 35031014

Variant Present in the following documents:

12864_2021_8289_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2310_2311insGGG; D770_N771insG

PubMed Link: 33397889

Variant Present in the following documents:

41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

41467_2020_20162_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

Significant Improvement in Detecting BRAF, KRAS, and EGFR Mutations Using Next-Generation Sequencing as Compared with FDA-Cleared Kits.

Molecular Diagnosis & Therapy

Ma, Wanlong W; Brodie, Steven S; Agersborg, Sally S; Funari, Vincent A VA; Albitar, Maher M

Variant ID: 7-55249012-C-CGGG

NM_005228.3(EGFR):c.2310_2311insGGG;(p.D770_N771insG)

This variant was identified in 8 publications

Variant-Specific Resource Links:

Publications:

Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications

Publication Date: 2023-02-08

Variant appearance in text: EGFR: 2310_2311insGGG; D770_N771insG

PubMed Link: 36755027

Variant Present in the following documents:

41467_2023_36328_MOESM6_ESM.xlsx, sheet 1

Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: EGFR: 2310_2311insGGG; D770_N771insG

PubMed Link: 35814426

Variant Present in the following documents:

DataSheet_1.xlsx, sheet 2

Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW

Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2310_2311insGGG; Asp770_Asn771insGly

PubMed Link: 35606799

Variant Present in the following documents:

41021_2022_248_MOESM1_ESM.xlsx, sheet 1

Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2310_2311insGGG; D770_N771insG

PubMed Link: 35273153

Variant Present in the following documents:

41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: EGFR: 2310_2311insGGG; Asp770_Asn771insGly

PubMed Link: 35031014

Variant Present in the following documents:

12864_2021_8289_MOESM1_ESM.xlsx, sheet 1

Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: EGFR: 2310_2311insGGG; Asp770_Asn771insGly

PubMed Link: 35031014

Variant Present in the following documents:

12864_2021_8289_MOESM1_ESM.xlsx, sheet 1

Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2310_2311insGGG; D770_N771insG

PubMed Link: 33397889

Variant Present in the following documents:

41467_2020_20162_MOESM6_ESM.xlsx, sheet 1 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1

Significant Improvement in Detecting BRAF, KRAS, and EGFR Mutations Using Next-Generation Sequencing as Compared with FDA-Cleared Kits.

Molecular Diagnosis & Therapy

Ma, Wanlong W; Brodie, Steven S; Agersborg, Sally S; Funari, Vincent A VA; Albitar, Maher M

Publication Date: 2017-10

Variant appearance in text: EGFR: 2310_2311insGGG; Asp770_Asn771insGly

PubMed Link: 28639239

Variant Present in the following documents:

Main text 40291_2017_Article_290.pdf

41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

41467_2020_20162_MOESM10_ESM.xlsx, sheet 1

Main text

40291_2017_Article_290.pdf