Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Comparison of next generation sequencing, SNaPshot assay and real-time polymerase chain reaction for lung adenocarcinoma EGFR mutation assessment.
Bmc Pulmonary Medicine
Cernomaz, Andrei-Tudor AT; Macovei, Ina Iuliana II; Pavel, Ionut I; Grigoriu, Carmen C; Marinca, Mihai M; Baty, Florent F; Peter, Simona S; Zonda, Radu R; Brutsche, Martin M; Grigoriu, Bogdan- Dragos B