EGFR c.2326C>A ;(p.R776S)

Variant ID: 7-55249028-C-A

NM_005228.3(EGFR):c.2326C>A;(p.R776S)

This variant was identified in 16 publications

View GRCh38 version.




Publications:


Pan-cancer clinical impact of latent drivers from double mutations.

Communications Biology
Yavuz, Bengi Ruken BR; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Tuncbag, Nurcan N
Publication Date: 2023-02-20

Variant appearance in text: EGFR: R776S
PubMed Link: 36808143
Variant Present in the following documents:
  • 42003_2023_4519_MOESM3_ESM.xlsx, sheet 3
View BVdb publication page



Phasing analysis of lung cancer genomes using a long read sequencer.

Nature Communications
Sakamoto, Yoshitaka Y; Miyake, Shuhei S; Oka, Miho M; Kanai, Akinori A; Kawai, Yosuke Y; Nagasawa, Satoi S; Shiraishi, Yuichi Y; Tokunaga, Katsushi K; Kohno, Takashi T; Seki, Masahide M; Suzuki, Yutaka Y; Suzuki, Ayako A
Publication Date: 2022-06-16

Variant appearance in text: EGFR: R776S
PubMed Link: 35710642
Variant Present in the following documents:
  • Main text
  • 41467_2022_Article_31133.pdf
  • 41467_2022_31133_MOESM1_ESM.pdf
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Genomic profiling reveals non-small cell lung cancer with common mutations of EGFR exon 20 and exon 21: a case report.

Translational Cancer Research
Bi, Xiaojun X; Song, Pengyu P; Wang, Chengye C; Zhang, Xuefei X; Liu, Changhong C
Publication Date: 2022-05

Variant appearance in text: EGFR: 2326C>A; R776S
PubMed Link: 35706785
Variant Present in the following documents:
  • Main text
  • tcr-11-05-1423.pdf
View BVdb publication page



Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05

Variant appearance in text: EGFR: Arg776Ser
PubMed Link: 35244186
Variant Present in the following documents:
  • Supplementary_Data3.xlsx, sheet 1
View BVdb publication page



Identification of the Unique Clinical and Genetic Features of Chinese Lung Cancer Patients With EGFR Germline Mutations in a Large-Scale Retrospective Study.

Frontiers In Oncology
Lin, Xinqing X; Peng, Muyun M; Chen, Quanfang Q; Yuan, Mingming M; Chen, Rongrong R; Deng, Haiyi H; Deng, Jiaxi J; Liu, Ouqi O; Weng, Yuqing Y; Chen, Mingjiu M; Zhou, Chengzhi C
Publication Date: 2021

Variant appearance in text: EGFR: R776S
PubMed Link: 34869019
Variant Present in the following documents:
  • Main text
  • fonc-11-774156.pdf
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Arg776Ser
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Arg776Ser
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



An Observational Study to Assess the Molecular Epidemiology and Direct Medical Costs of Epidermal Growth Factor Receptor (EGFR) Mutations in Patients with Advanced EGFR Mutation-Positive Non-Small Cell Lung Cancer Treated with Afatinib in Real-World Clinical Settings in Greece.

Lung Cancer (Auckland, N.Z.)
Mountzios, Giannis G; Lampaki, Sofia S; Koliou, Georgia-Angeliki GA; Vozikis, Athanassios A; Kontogiorgos, Ioannis I; Papantoniou, Panagiotis P; Koufaki, Margarita-Ioanna MI; Res, Eleni E; Boutis, Anastasios A; Christopoulou, Athina A; Pastelli, Nicoleta N; Grivas, Anastasios A; Aravantinos, Gerasimos G; Lalla, Efthalia E; Oikonomopoulos, Georgios G; Koumarianou, Anna A; Spyratos, Dionisios D; Bafaloukos, Dimitrios D; Rigakos, Georgios G; Papakotoulas, Pavlos P; Fountzilas, George G; Linardou, Helena H
Publication Date: 2021

Variant appearance in text: EGFR: R776S
PubMed Link: 34512058
Variant Present in the following documents:
  • Main text
  • lctt-12-93.pdf
View BVdb publication page



A Real-World, Observational, Prospective Study to Assess the Molecular Epidemiology of Epidermal Growth Factor Receptor (EGFR) Mutations upon Progression on or after First-Line Therapy with a First- or Second-Generation EGFR Tyrosine Kinase Inhibitor in EGFR Mutation-Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer: The 'LUNGFUL' Study.

Cancers
Mountzios, Giannis G; Koumarianou, Anna A; Bokas, Alexandros A; Mavroudis, Dimitrios D; Samantas, Epaminondas E; Fergadis, Evangelos Georgios EG; Linardou, Helena H; Katsaounis, Panagiotis P; Athanasiadis, Elias E; Karamouzis, Michalis V MV; Pentheroudakis, George G; Lampaki, Sofia S; Froudarakis, Marios E ME; Perdikouri, Eleni-Isidora A EA; Somarakis, Alvertos A; Papageorgiou, Foteini F; Paparepa, Zoe Z; Nikolaou, Aristeidis A; Syrigos, Konstantinos N KN
Publication Date: 2021-06-25

Variant appearance in text: EGFR: R776S
PubMed Link: 34202063
Variant Present in the following documents:
  • Main text
  • cancers-13-03172.pdf
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2326C>A; R776S
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Better Progression-Free Survival in Elderly Patients with Stage IV Lung Adenocarcinoma Harboring Uncommon Epidermal Growth Factor Receptor Mutations Treated with the First-line Tyrosine Kinase Inhibitors.

Cancers
Tsai, Ming-Ju MJ; Hung, Jen-Yu JY; Lee, Mei-Hsuan MH; Kuo, Chia-Yu CY; Tsai, Yu-Chen YC; Tsai, Ying-Ming YM; Liu, Ta-Chih TC; Yang, Chih-Jen CJ; Huang, Ming-Shyan MS; Chong, Inn-Wen IW
Publication Date: 2018-11-13

Variant appearance in text: EGFR: R776S
PubMed Link: 30428509
Variant Present in the following documents:
  • Main text
  • cancers-10-00434.pdf
View BVdb publication page



Genomic alterations of ground-glass nodular lung adenocarcinoma.

Scientific Reports
Lee, Hyun H; Joung, Je-Gun JG; Shin, Hyun-Tae HT; Kim, Duk-Hwan DH; Kim, Yujin Y; Kim, Hojoong H; Kwon, O Jung OJ; Shim, Young Mog YM; Lee, Ho Yun HY; Lee, Kyung Soo KS; Choi, Yoon-La YL; Park, Woong-Yang WY; Hayes, D Neil DN; Um, Sang-Won SW
Publication Date: 2018-05-16

Variant appearance in text: EGFR: R776S
PubMed Link: 29769567
Variant Present in the following documents:
  • Main text
  • 41598_2018_25800_MOESM2_ESM.xlsx, sheet 1
  • 41598_2018_Article_25800.pdf
View BVdb publication page



Screening for EGFR and KRAS mutations in non-small cell lung carcinomas using DNA extraction by hydrothermal pressure coupled with PCR-based direct sequencing.

International Journal Of Clinical And Experimental Pathology
Liu, Yan Y; Wu, Bing-Quan BQ; Zhong, Hao-Hao HH; Hui, Pei P; Fang, Wei-Gang WG
Publication Date: 2013

Variant appearance in text: EGFR: R776S
PubMed Link: 24040454
Variant Present in the following documents:
  • Main text
View BVdb publication page



EGFR mutation testing in patients with advanced non-small cell lung cancer: a comprehensive evaluation of real-world practice in an East Asian tertiary hospital.

Plos One
Choi, Yoon-La YL; Sun, Jong-Mu JM; Cho, Juhee J; Rampal, Sanjay S; Han, Joungho J; Parasuraman, Bhash B; Guallar, Eliseo E; Lee, Genehee G; Lee, Jeeyun J; Shim, Young Mog YM
Publication Date: 2013

Variant appearance in text: EGFR: R776S
PubMed Link: 23468851
Variant Present in the following documents:
  • Main text
  • pone.0056011.pdf
View BVdb publication page



Compound EGFR mutations and response to EGFR tyrosine kinase inhibitors.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Kobayashi, Susumu S; Canepa, Hannah M HM; Bailey, Alexandra S AS; Nakayama, Sohei S; Yamaguchi, Norihiro N; Goldstein, Michael A MA; Huberman, Mark S MS; Costa, Daniel B DB
Publication Date: 2013-01

Variant appearance in text: EGFR: R776S
PubMed Link: 23242437
Variant Present in the following documents:
  • Main text
View BVdb publication page



The impact of initial gefitinib or erlotinib versus chemotherapy on central nervous system progression in advanced non-small cell lung cancer with EGFR mutations.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Heon, Stephanie S; Yeap, Beow Y BY; Lindeman, Neal I NI; Joshi, Victoria A VA; Butaney, Mohit M; Britt, Gregory J GJ; Costa, Daniel B DB; Rabin, Michael S MS; Jackman, David M DM; Johnson, Bruce E BE
Publication Date: 2012-08-15

Variant appearance in text: EGFR: R776S
PubMed Link: 22733536
Variant Present in the following documents:
  • Main text
View BVdb publication page



Erlotinib at a dose of 25 mg daily for non-small cell lung cancers with EGFR mutations.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Yeo, Wee-Lee WL; Riely, Gregory J GJ; Yeap, Beow Y BY; Lau, Michelle W MW; Warner, Jeremy L JL; Bodio, Kelly K; Huberman, Mark S MS; Kris, Mark G MG; Tenen, Daniel G DG; Pao, William W; Kobayashi, Susumu S; Costa, Daniel B DB
Publication Date: 2010-07

Variant appearance in text: EGFR: R776S
PubMed Link: 20512075
Variant Present in the following documents:
  • Main text
View BVdb publication page