EGFR c.2354C>T ;(p.T785I)

Variant ID: 7-55249056-C-T

NM_005228.3(EGFR):c.2354C>T;(p.T785I)

This variant was identified in 13 publications

View GRCh38 version.




Publications:


Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-04

Variant appearance in text: EGFR: T785I
PubMed Link: 35304574
Variant Present in the following documents:
  • 41388_2022_Article_2263.pdf
View BVdb publication page



Targeted genomic analysis of cutaneous T cell lymphomas identifies a subset with aggressive clinicopathological features.

Blood Cancer Journal
Argyropoulos, Kimon V KV; Pulitzer, Melissa M; Maura, Francesco F; Mohanty, Abhinita A; Mondello, Patrizia P; Horwitz, Steven M SM; Myskowski, Patricia P; Moskowitz, Alison A; Dogan, Ahmet A; Querfeld, Christiane C; Rapaport, Franck F; Siakantaris, Marina M; Louis, Peter C PC; Galasso, Natasha N; van den Brink, Marcel R M MRM; Palomba, M Lia ML
Publication Date: 2020-11-09

Variant appearance in text: EGFR: 2354C>T; T785I
PubMed Link: 33168809
Variant Present in the following documents:
  • 41408_2020_380_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



ErBb Family Proteins in Cholangiocarcinoma and Clinical Implications.

Journal Of Clinical Medicine
Jin, Wook W
Publication Date: 2020-07-16

Variant appearance in text: EGFR: T785I
PubMed Link: 32708604
Variant Present in the following documents:
  • Main text
  • jcm-09-02255.pdf
View BVdb publication page



New therapeutic approaches to overcoming resistant EGFR exon 20 alterations.

Critical Reviews In Oncology/Hematology
Li, Alex M AM; Boichard, Amélie A; Felip, Enriqueta E; Kurzrock, Razelle R
Publication Date: 2020-07

Variant appearance in text: EGFR: T785I
PubMed Link: 32485428
Variant Present in the following documents:
  • Main text
View BVdb publication page



Characterization of epidermal growth factor receptor (EGFR) P848L, an unusual EGFR variant present in lung cancer patients, in a murine Ba/F3 model.

Febs Open Bio
Sarcar, Bhaswati B; Gimbrone, Nicholas T NT; Wright, Gabriela G; Remsing Rix, Lily L LL; Gordian, Edna R ER; Rix, Uwe U; Chiappori, Alberto A AA; Reuther, Gary W GW; Santiago-Cardona, Pedro G PG; Muñoz-Antonia, Teresita T; Cress, William Douglas WD
Publication Date: 2019-10

Variant appearance in text: EGFR: T785I
PubMed Link: 31314158
Variant Present in the following documents:
  • Main text
  • FEB4-9-1689.pdf
View BVdb publication page



Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma.

Nature Communications
North, Jeffrey P JP; Golovato, Justin J; Vaske, Charles J CJ; Sanborn, J Zachary JZ; Nguyen, Andrew A; Wu, Wei W; Goode, Benjamin B; Stevers, Meredith M; McMullen, Kevin K; Perez White, Bethany E BE; Collisson, Eric A EA; Bloomer, Michele M; Solomon, David A DA; Benz, Stephen C SC; Cho, Raymond J RJ
Publication Date: 2018-05-14

Variant appearance in text: EGFR: T785I
PubMed Link: 29760388
Variant Present in the following documents:
  • 41467_2018_4008_MOESM3_ESM.xlsx, sheet 32
View BVdb publication page



Clinical Analysis of Uncommon Epidermal Growth Factor Receptor Mutations in 16 Cases of Nonsmall Cell Lung Cancer.

Chinese Medical Journal
Hu, Ai-Min AM; Li, Yun-Song YS; Zhao, Dan D; Hu, Fan-Bin FB; Wang, Qun-Hui QH; Li, Bao-Lan BL
Publication Date: 2018-04-20

Variant appearance in text: EGFR: T785I
PubMed Link: 29664067
Variant Present in the following documents:
  • CMJ-131-1005.pdf
View BVdb publication page



Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Cancer Biology & Therapy
Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS
Publication Date: 2016

Variant appearance in text: EGFR: T785I
PubMed Link: 26785607
Variant Present in the following documents:
  • Main text
  • kcbt-17-03-1139235.pdf
View BVdb publication page



Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma.

Bmc Cancer
Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Kim, Arum A; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS
Publication Date: 2016-01-18

Variant appearance in text: EGFR: 2354C>T
PubMed Link: 26782967
Variant Present in the following documents:
  • 12885_2016_2049_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Protein domain-level landscape of cancer-type-specific somatic mutations.

Plos Computational Biology
Yang, Fan F; Petsalaki, Evangelia E; Rolland, Thomas T; Hill, David E DE; Vidal, Marc M; Roth, Frederick P FP
Publication Date: 2015-03

Variant appearance in text: EGFR: T785I
PubMed Link: 25794154
Variant Present in the following documents:
  • pcbi.1004147.s001.xlsx, sheet 1
View BVdb publication page



Next-generation sequencing of lung cancer EGFR exons 18-21 allows effective molecular diagnosis of small routine samples (cytology and biopsy).

Plos One
de Biase, Dario D; Visani, Michela M; Malapelle, Umberto U; Simonato, Francesca F; Cesari, Valentina V; Bellevicine, Claudio C; Pession, Annalisa A; Troncone, Giancarlo G; Fassina, Ambrogio A; Tallini, Giovanni G
Publication Date: 2013

Variant appearance in text: EGFR: T785I
PubMed Link: 24376723
Variant Present in the following documents:
  • Main text
  • pone.0083607.pdf
View BVdb publication page



Thymoma patients treated in a phase I clinic at MD Anderson Cancer Center: responses to mTOR inhibitors and molecular analyses.

Oncotarget
Wheler, Jennifer J; Hong, David D; Swisher, Stephen G SG; Falchook, Gerald G; Tsimberidou, Apostolia M AM; Helgason, Thorunn T; Naing, Aung A; Stephen, Bettzy B; Janku, Filip F; Stephens, Philip J PJ; Yelensky, Roman R; Kurzrock, Razelle R
Publication Date: 2013-06

Variant appearance in text: EGFR: T785I
PubMed Link: 23765114
Variant Present in the following documents:
  • Main text
  • oncotarget-04-890.pdf
View BVdb publication page



Aberrations in the epidermal growth factor receptor gene in 958 patients with diverse advanced tumors: implications for therapy.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology
Wheler, J J JJ; Falchook, G S GS; Tsimberidou, A M AM; Hong, D S DS; Naing, A A; Piha-Paul, S A SA; Chen, S S SS; Fu, S S; Stephen, B B; Fok, J Y JY; Janku, F F; Kurzrock, R R
Publication Date: 2013-03

Variant appearance in text: EGFR: T785I
PubMed Link: 23139256
Variant Present in the following documents:
  • Main text
View BVdb publication page