EGFR c.2362C>T ;(p.L788F)

Variant ID: 7-55249064-C-T

NM_005228.3(EGFR):c.2362C>T;(p.L788F)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Mutational Analysis of EGFR Mutations in Non-Small Cell Lung Carcinoma-An Indian Perspective of 212 Patients.

International Journal Of Environmental Research And Public Health
Kaler, Amrit Kaur AK; Patel, Khushi K; Patil, Harshali H; Tiwarekar, Yash Y; Kulkarni, Bijal B; Hastak, Meenal M; Athikari, Nivetha N; Rane, Samrudhi S; Nikam, Ankita A; Umarji, Smita S; Shaikh, Imran I; Goyle, Sandeep S; Mistry, Rajesh R
Publication Date: 2022-12-31

Variant appearance in text: EGFR: 2362C>T
PubMed Link: 36613084
Variant Present in the following documents:
  • ijerph-20-00758.pdf
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: EGFR: Leu788Phe
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-04

Variant appearance in text: EGFR: L788F
PubMed Link: 35304574
Variant Present in the following documents:
  • 41388_2022_Article_2263.pdf
View BVdb publication page



Competitive evolution of NSCLC tumor clones and the drug resistance mechanism of first-generation EGFR-TKIs in Chinese NSCLC patients.

Heliyon
Deng, Qinfang Q; Xie, Boxiong B; Wu, Leilei L; Ji, Xianxiu X; Li, Chao C; Feng, Li L; Fang, Qiyu Q; Bao, Yuchen Y; Li, Jialu J; Jin, Shengnan S; Ding, Chunming C; Li, Yixue Y; Zhou, Songwen S
Publication Date: 2018-12

Variant appearance in text: EGFR: L788F
PubMed Link: 30603682
Variant Present in the following documents:
  • mmc2.xlsx, sheet 1
View BVdb publication page



Combining Mutational Signatures, Clonal Fitness, and Drug Affinity to Define Drug-Specific Resistance Mutations in Cancer.

Cell Chemical Biology
Kaserer, Teresa T; Blagg, Julian J
Publication Date: 2018-11-15

Variant appearance in text: EGFR: L788F
PubMed Link: 30146241
Variant Present in the following documents:
  • Main text
  • mmc9.pdf
  • main.pdf
View BVdb publication page



Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket.

Chemical Science
Kannan, Srinivasaraghavan S; Venkatachalam, Gireedhar G; Lim, Hong Hwa HH; Surana, Uttam U; Verma, Chandra C
Publication Date: 2018-06-21

Variant appearance in text: EGFR: L788F
PubMed Link: 29997876
Variant Present in the following documents:
  • Main text
  • SC-009-C8SC01262H.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: L788F
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
View BVdb publication page



Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib.

Scientific Reports
Kannan, Srinivasaraghavan S; Pradhan, Mohan R MR; Tiwari, Garima G; Tan, Wei-Chong WC; Chowbay, Balram B; Tan, Eng Huat EH; Tan, Daniel Shao-Weng DS; Verma, Chandra C
Publication Date: 2017-05-08

Variant appearance in text: EGFR: L788F
PubMed Link: 28484248
Variant Present in the following documents:
View BVdb publication page



Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Nature Medicine
Xie, Mingchao M; Lu, Charles C; Wang, Jiayin J; McLellan, Michael D MD; Johnson, Kimberly J KJ; Wendl, Michael C MC; McMichael, Joshua F JF; Schmidt, Heather K HK; Yellapantula, Venkata V; Miller, Christopher A CA; Ozenberger, Bradley A BA; Welch, John S JS; Link, Daniel C DC; Walter, Matthew J MJ; Mardis, Elaine R ER; Dipersio, John F JF; Chen, Feng F; Wilson, Richard K RK; Ley, Timothy J TJ; Ding, Li L
Publication Date: 2014-12

Variant appearance in text: EGFR: L788F
PubMed Link: 25326804
Variant Present in the following documents:
  • NIHMS630249-supplement-6.xlsx, sheet 1
View BVdb publication page



Screening for EGFR and KRAS mutations in non-small cell lung carcinomas using DNA extraction by hydrothermal pressure coupled with PCR-based direct sequencing.

International Journal Of Clinical And Experimental Pathology
Liu, Yan Y; Wu, Bing-Quan BQ; Zhong, Hao-Hao HH; Hui, Pei P; Fang, Wei-Gang WG
Publication Date: 2013

Variant appearance in text: EGFR: L788F
PubMed Link: 24040454
Variant Present in the following documents:
  • Main text
View BVdb publication page