EGFR c.2368A>G ;(p.T790A)

Variant ID: 7-55249070-A-G

NM_005228.3(EGFR):c.2368A>G;(p.T790A)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


Human Papillomavirus Infection and EGFR Exon 20 Insertions in Sinonasal Inverted Papilloma and Squamous Cell Carcinoma.

Journal Of Personalized Medicine
Hirakawa, Hitoshi H; Ikegami, Taro T; Kise, Norimoto N; Kinjyo, Hidetoshi H; Kondo, Shunsuke S; Agena, Shinya S; Hasegawa, Narumi N; Kawakami, Junko J; Maeda, Hiroyuki H; Suzuki, Mikio M
Publication Date: 2023-04-11

Variant appearance in text: EGFR: T790A
PubMed Link: 37109043
Variant Present in the following documents:
  • jpm-13-00657.pdf
View BVdb publication page



Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis.

Clinical And Translational Gastroenterology
Cowan, Robert W RW; Pratt, Erica D ED; Kang, Jin Muk JM; Zhao, Jun J; Wilhelm, Joshua J JJ; Abdulla, Muhamad M; Qiao, Edmund M EM; Brennan, Luke P LP; Ulintz, Peter J PJ; Bellin, Melena D MD; Rhim, Andrew D AD
Publication Date: 2021-11-18

Variant appearance in text: EGFR: 2368A>G; T790A
PubMed Link: 34797250
Variant Present in the following documents:
  • ct9-12-e00431-s006.xlsx, sheet 1
View BVdb publication page



Landscape of drug-resistance mutations in kinase regulatory hotspots.

Briefings In Bioinformatics
Kim, Pora P; Li, Hanyang H; Wang, Junmei J; Zhao, Zhongming Z
Publication Date: 2021-05-20

Variant appearance in text: EGFR: T790A
PubMed Link: 32510566
Variant Present in the following documents:
  • Main text
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: T790A
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas.

Acta Neuropathologica Communications
Salloum, Ralph R; McConechy, Melissa K MK; Mikael, Leonie G LG; Fuller, Christine C; Drissi, Rachid R; DeWire, Mariko M; Nikbakht, Hamid H; De Jay, Nicolas N; Yang, Xiaodan X; Boue, Daniel D; Chow, Lionel M L LML; Finlay, Jonathan L JL; Gayden, Tenzin T; Karamchandani, Jason J; Hummel, Trent R TR; Olshefski, Randal R; Osorio, Diana S DS; Stevenson, Charles C; Kleinman, Claudia L CL; Majewski, Jacek J; Fouladi, Maryam M; Jabado, Nada N
Publication Date: 2017-10-30

Variant appearance in text: EGFR: T790A
PubMed Link: 29084603
Variant Present in the following documents:
  • 40478_2017_479_MOESM2_ESM.xlsx, sheet 10
View BVdb publication page



Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Publication Date: 2017-04

Variant appearance in text: EGFR: 2368A>G; T790A
PubMed Link: 28179366
Variant Present in the following documents:
  • supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1
View BVdb publication page



Diagnostic value of H3F3A mutations in giant cell tumour of bone compared to osteoclast-rich mimics.

The Journal Of Pathology. Clinical Research
Presneau, Nadège N; Baumhoer, Daniel D; Behjati, Sam S; Pillay, Nischalan N; Tarpey, Patrick P; Campbell, Peter J PJ; Jundt, Gernot G; Hamoudi, Rifat R; Wedge, David C DC; Loo, Peter Van PV; Hassan, A Bassim AB; Khatri, Bhavisha B; Ye, Hongtao H; Tirabosco, Roberto R; Amary, M Fernanda MF; Flanagan, Adrienne M AM
Publication Date: 2015-04

Variant appearance in text: EGFR: 2368A>G; T790A
PubMed Link: 27499898
Variant Present in the following documents:
  • CJP2-1-113-s004.xlsx, sheet 1
View BVdb publication page



Prognostic value analysis of mutational and clinicopathological factors in non-small cell lung cancer.

Plos One
Li, Chenguang C; Hao, Ligang L; Li, Yue Y; Wang, Shengguang S; Chen, Hui H; Zhang, Lianmin L; Ke, Bin B; Yin, Yuesong Y; Suo, Haijin H; Sun, Bingsheng B; Zhang, Bin B; Wang, Changli C
Publication Date: 2014

Variant appearance in text: EGFR: T790A
PubMed Link: 25198510
Variant Present in the following documents:
  • Main text
  • pone.0107276.pdf
View BVdb publication page



Drug resistance missense mutations in cancer are subject to evolutionary constraints.

Plos One
Friedman, Ran R
Publication Date: 2013

Variant appearance in text: EGFR: T790A
PubMed Link: 24376513
Variant Present in the following documents:
  • Main text
  • pone.0082059.pdf
View BVdb publication page