EGFR c.2369_2370delinsTC ;(p.T790I)

Variant ID: 7-55249071-CG-TC

NM_005228.3(EGFR):c.2369_2370delinsTC;(p.T790I)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Identification of a Rare EGFR T790I Mutation in Lung Adenocarcinoma Sensitive to Osimertinib.

Frontiers In Oncology
Wang, Yu Y; Liu, Songtao S; Feng, Alei A; Luo, Huan H; Hu, Jinwei J; Wang, Kai K; Dong, Wei W
Publication Date: 2021

Variant appearance in text: EGFR: T790I
PubMed Link: 34745948
Variant Present in the following documents:
  • Main text
  • fonc-11-727312.pdf
View BVdb publication page



Identification of a Water-Coordinating HER2 Inhibitor by Virtual Screening Using Similarity-Based Scoring.

Biochemistry
Guo, Jiaye J; Collins, Stephen S; Miller, W Todd WT; Rizzo, Robert C RC
Publication Date: 2018-08-14

Variant appearance in text: EGFR: T790I
PubMed Link: 29975516
Variant Present in the following documents:
  • Main text
  • bi8b00524.pdf
View BVdb publication page



Evaluating the predictivity of virtual screening for ABL kinase inhibitors to hinder drug resistance.

Chemical Biology & Drug Design
Gani, Osman A B S M OA; Narayanan, Dilip D; Engh, Richard A RA
Publication Date: 2013-11

Variant appearance in text: EGFR: T790I
PubMed Link: 23746052
Variant Present in the following documents:
  • cbdd0082-0506.pdf
View BVdb publication page



Activation of tyrosine kinases by mutation of the gatekeeper threonine.

Nature Structural & Molecular Biology
Azam, Mohammad M; Seeliger, Markus A MA; Gray, Nathanael S NS; Kuriyan, John J; Daley, George Q GQ
Publication Date: 2008-10

Variant appearance in text: EGFR: T790I
PubMed Link: 18794843
Variant Present in the following documents:
  • Main text
  • nihms-70040.pdf
View BVdb publication page