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EGFR c.2369_2370delinsTC ;(p.T790I)
Variant ID: 7-55249071-CG-TC
NM_005228.3(
EGFR
):c.2369_2370delinsTC;(p.T790I)
This variant was identified in 4 publications
View GRCh38 version.
Variant-Specific Resource Links:
gnomAD v2.1.1
Mutalizer Name Checker
Google
UCSC Genome Browser
ClinVar
dbSNP
Publications:
Identification of a Rare EGFR T790I Mutation in Lung Adenocarcinoma Sensitive to Osimertinib.
Frontiers In Oncology
Wang, Yu Y; Liu, Songtao S; Feng, Alei A; Luo, Huan H; Hu, Jinwei J; Wang, Kai K; Dong, Wei W
Publication Date: 2021
Variant appearance in text: EGFR: T790I
PubMed Link:
34745948
Variant Present in the following documents:
Main text
fonc-11-727312.pdf
View BVdb publication page
Identification of a Water-Coordinating HER2 Inhibitor by Virtual Screening Using Similarity-Based Scoring.
Biochemistry
Guo, Jiaye J; Collins, Stephen S; Miller, W Todd WT; Rizzo, Robert C RC
Publication Date: 2018-08-14
Variant appearance in text: EGFR: T790I
PubMed Link:
29975516
Variant Present in the following documents:
Main text
bi8b00524.pdf
View BVdb publication page
Evaluating the predictivity of virtual screening for ABL kinase inhibitors to hinder drug resistance.
Chemical Biology & Drug Design
Gani, Osman A B S M OA; Narayanan, Dilip D; Engh, Richard A RA
Publication Date: 2013-11
Variant appearance in text: EGFR: T790I
PubMed Link:
23746052
Variant Present in the following documents:
cbdd0082-0506.pdf
View BVdb publication page
Activation of tyrosine kinases by mutation of the gatekeeper threonine.
Nature Structural & Molecular Biology
Azam, Mohammad M; Seeliger, Markus A MA; Gray, Nathanael S NS; Kuriyan, John J; Daley, George Q GQ
Publication Date: 2008-10
Variant appearance in text: EGFR: T790I
PubMed Link:
18794843
Variant Present in the following documents:
Main text
nihms-70040.pdf
View BVdb publication page