EGFR c.2374C>T ;(p.L792F)

Variant ID: 7-55249076-C-T

NM_005228.3(EGFR):c.2374C>T;(p.L792F)

This variant was identified in 84 publications

View GRCh38 version.




Publications:


Challenges of EGFR-TKIs in NSCLC and the potential role of herbs and active compounds: From mechanism to clinical practice.

Frontiers In Pharmacology
Song, Xiaotong X; Cao, Luchang L; Ni, Baoyi B; Wang, Jia J; Qin, Xiaoyan X; Sun, Xiaoyue X; Xu, Bowen B; Wang, Xinmiao X; Li, Jie J
Publication Date: 2023

Variant appearance in text: EGFR: L792F
PubMed Link: 37089959
Variant Present in the following documents:
  • Main text
  • fphar-14-1090500.pdf
View BVdb publication page



Toward the next generation EGFR inhibitors: an overview of osimertinib resistance mediated by EGFR mutations in non-small cell lung cancer.

Cell Communication And Signaling : Ccs
Li, Yufeng Y; Mao, Tianyu T; Wang, Jing J; Zheng, Hongrui H; Hu, Ziyi Z; Cao, Pingping P; Yang, Suisui S; Zhu, Lingyun L; Guo, Shunyao S; Zhao, Xinfei X; Tian, Yue Y; Shen, Hua H; Lin, Fan F
Publication Date: 2023-04-11

Variant appearance in text: EGFR: L792F
PubMed Link: 37041601
Variant Present in the following documents:
  • 12964_2023_Article_1082.pdf
View BVdb publication page



circPTPN12 promotes the progression and sunitinib resistance of renal cancer via hnRNPM/IL-6/STAT3 pathway.

Cell Death & Disease
Shou, Yi Y; Yue, Changjie C; Wang, Qi Q; Liu, Jingchong J; Xu, Jiaju J; Miao, Qi Q; Liu, Di D; Yang, Hongmei H; Liu, Yuenan Y; Zhang, Xiaoping X
Publication Date: 2023-03-31

Variant appearance in text: EGFR: L792F
PubMed Link: 37002206
Variant Present in the following documents:
  • 41419_2023_Article_5717.pdf
View BVdb publication page



Analysis of acquired resistance mechanisms to osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer from the AURA3 trial.

Nature Communications
Chmielecki, Juliann J; Mok, Tony T; Wu, Yi-Long YL; Han, Ji-Youn JY; Ahn, Myung-Ju MJ; Ramalingam, Suresh S SS; John, Thomas T; Okamoto, Isamu I; Yang, James Chih-Hsin JC; Shepherd, Frances A FA; Bulusu, Krishna C KC; Laus, Gianluca G; Collins, Barbara B; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Papadimitrakopoulou, Vassiliki V
Publication Date: 2023-02-27

Variant appearance in text: EGFR: L792F
PubMed Link: 36849516
Variant Present in the following documents:
  • Main text
  • 41467_2023_Article_35962.pdf
  • 41467_2023_35962_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Therapeutic strategies for EGFR-mutated non-small cell lung cancer patients with osimertinib resistance.

Journal Of Hematology & Oncology
Fu, Kai K; Xie, Fachao F; Wang, Fang F; Fu, Liwu L
Publication Date: 2022-12-08

Variant appearance in text: EGFR: L792F
PubMed Link: 36482474
Variant Present in the following documents:
  • 13045_2022_Article_1391.pdf
View BVdb publication page



Engaging innate immunity for targeting the epidermal growth factor receptor: Therapeutic options leveraging innate immunity versus adaptive immunity versus inhibition of signaling.

Frontiers In Oncology
Hintzen, Gabriele G; Dulat, Holger J HJ; Rajkovic, Erich E
Publication Date: 2022

Variant appearance in text: EGFR: L792F
PubMed Link: 36185288
Variant Present in the following documents:
  • Main text
  • fonc-12-892212.pdf
View BVdb publication page



Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective.

Signal Transduction And Targeted Therapy
Yang, Yang Y; Li, Shuo S; Wang, Yujiao Y; Zhao, Yi Y; Li, Qiu Q
Publication Date: 2022-09-17

Variant appearance in text: EGFR: L792F
PubMed Link: 36115852
Variant Present in the following documents:
  • 41392_2022_Article_1168.pdf
View BVdb publication page



Non-small cell lung cancer in China.

Cancer Communications (London, England)
Chen, Peixin P; Liu, Yunhuan Y; Wen, Yaokai Y; Zhou, Caicun C
Publication Date: 2022-10

Variant appearance in text: EGFR: L792F
PubMed Link: 36075878
Variant Present in the following documents:
  • Main text
  • CAC2-42-937.pdf
View BVdb publication page



Blockade of STAT3/IL-4 overcomes EGFR T790M-cis-L792F-induced resistance to osimertinib via suppressing M2 macrophages polarization.

Ebiomedicine
Sun, Yiting Y; Dong, Yiting Y; Liu, Xijuan X; Zhang, Yundi Y; Bai, Hua H; Duan, Jianchun J; Tian, Zhihua Z; Yan, Xiang X; Wang, Jie J; Wang, Zhijie Z
Publication Date: 2022-09

Variant appearance in text: EGFR: L792F
PubMed Link: 35932642
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Emerging strategies to overcome resistance to third-generation EGFR inhibitors.

Journal Of Hematology & Oncology
Shi, Kunyu K; Wang, Guan G; Pei, Junping J; Zhang, Jifa J; Wang, Jiaxing J; Ouyang, Liang L; Wang, Yuxi Y; Li, Weimin W
Publication Date: 2022-07-15

Variant appearance in text: EGFR: L792F
PubMed Link: 35840984
Variant Present in the following documents:
  • Main text
  • 13045_2022_Article_1311.pdf
View BVdb publication page



AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery
Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,
Publication Date: 2022-09-02

Variant appearance in text: EGFR: L792F
PubMed Link: 35819403
Variant Present in the following documents:
  • cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1
View BVdb publication page



Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology
Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J
Publication Date: 2022

Variant appearance in text: EGFR: 2374C>T; L792F
PubMed Link: 35814426
Variant Present in the following documents:
  • DataSheet_1.xlsx, sheet 2
View BVdb publication page



Molecular landscape and therapeutic alterations in Asian soft-tissue sarcoma patients.

Cancer Medicine
Gan, Meifu M; Zhang, Chen C; Qiu, Liqing L; Wang, Yue Y; Bao, Hua H; Yu, Ruoying R; Liu, Rui R; Wu, Xue X; Shao, Yang Y; Hou, Peifeng P; Fei, Zhenglei Z
Publication Date: 2022-11

Variant appearance in text: EGFR: 2374C>T; L792F
PubMed Link: 35586877
Variant Present in the following documents:
  • CAM4-11-4070-s004.xlsx, sheet 1
View BVdb publication page



RET kinase alterations in targeted cancer therapy.

Cancer Drug Resistance (Alhambra, Calif.)
Liu, Xuan X; Hu, Xueqing X; Shen, Tao T; Li, Qi Q; Mooers, Blaine H M BHM; Wu, Jie J
Publication Date: 2020

Variant appearance in text: EGFR: L792F
PubMed Link: 35582449
Variant Present in the following documents:
  • cdr-3-472.pdf
View BVdb publication page



Osimertinib-Centered Therapy Against Uncommon Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer- A Mini Review.

Frontiers In Oncology
Song, Chengyang C; Yang, Xueying X
Publication Date: 2022

Variant appearance in text: EGFR: L792F
PubMed Link: 35494059
Variant Present in the following documents:
  • fonc-12-834585.pdf
View BVdb publication page



Preclinical Models for Acquired Resistance to Third-Generation EGFR Inhibitors in NSCLC: Functional Studies and Drug Combinations Used to Overcome Resistance.

Frontiers In Oncology
Mahfoudhi, Emna E; Ricordel, Charles C; Lecuyer, Gwendoline G; Mouric, Cécile C; Lena, Hervé H; Pedeux, Rémy R
Publication Date: 2022

Variant appearance in text: EGFR: L792F
PubMed Link: 35463360
Variant Present in the following documents:
  • Main text
  • fonc-12-853501.pdf
View BVdb publication page



[Targeted Therapy and Mechanism of Drug Resistance in Non-small Cell Lung Cancer 
with Epidermal Growth Factor Receptor Gene Mutation].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Huang, Junxia J; Wang, Hong H
Publication Date: 2022-03-20

Variant appearance in text: EGFR: L792F
PubMed Link: 35340161
Variant Present in the following documents:
  • Main text
  • zgfazz-25-3-183.pdf
View BVdb publication page



Pedigree analysis of the EGFR p.V1010M germline mutation in a family with a family history of non-small-cell lung cancer.

Annals Of Translational Medicine
Li, Na N; Liu, Chunyi C; Xiong, Lan L; Huang, Depei D; Jiang, Youfan Y
Publication Date: 2022-02

Variant appearance in text: EGFR: L792F
PubMed Link: 35284553
Variant Present in the following documents:
  • Main text
  • atm-10-03-154.pdf
View BVdb publication page



The Role of TP53 Mutations in EGFR-Mutated Non-Small-Cell Lung Cancer: Clinical Significance and Implications for Therapy.

Cancers
Canale, Matteo M; Andrikou, Kalliopi K; Priano, Ilaria I; Cravero, Paola P; Pasini, Luigi L; Urbini, Milena M; Delmonte, Angelo A; Crinò, Lucio L; Bronte, Giuseppe G; Ulivi, Paola P
Publication Date: 2022-02-23

Variant appearance in text: EGFR: L792F
PubMed Link: 35267450
Variant Present in the following documents:
  • cancers-14-01143.pdf
View BVdb publication page



EGFR exon 19 deletion switch and development of p.L792Q mutation as a new resistance mechanism to osimertinib: a case report and literature review.

Translational Cancer Research
Pisapia, Pasquale P; Rocco, Danilo D; Pepe, Francesco F; De Luca, Caterina C; Battiloro, Ciro C; Smeraglio, Riccardo R; Cieri, Miriam M; Bellevicine, Claudio C; Troncone, Giancarlo G; Malapelle, Umberto U
Publication Date: 2019-01

Variant appearance in text: EGFR: L792F
PubMed Link: 35117065
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effective treatment of pulmonary adenocarcinoma harboring triple EGFR mutations of L858R, T790M, cis-G796s/cis-C797s by osimertinib, brigatinib, and bevacizumab combination therapy: A case report.

Respiratory Medicine Case Reports
Chang, Yuan Y; Liu, Shuang S; Jiang, Yanwen Y; Hua, Li L; Wen, Linfang L
Publication Date: 2022

Variant appearance in text: EGFR: L792F
PubMed Link: 35106279
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Effectiveness of alectinib and osimertinib in a brain metastasized lung adenocarcinoma patient with concurrent EGFR mutations and DCTN1-ALK fusion.

Thoracic Cancer
Yin, Qiang Q; Guo, Taiyan T; Zhou, Yangyang Y; Sun, Leina L; Meng, Maobin M; Ma, Li L; Wang, Xiaoguang X
Publication Date: 2022-02

Variant appearance in text: EGFR: L792F
PubMed Link: 34964276
Variant Present in the following documents:
  • TCA-13-637.pdf
View BVdb publication page



Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids.

Nature Communications
Gong, Ke K; Guo, Gao G; Beckley, Nicole A NA; Yang, Xiaoyao X; Zhang, Yue Y; Gerber, David E DE; Minna, John D JD; Burma, Sandeep S; Zhao, Dawen D; Akbay, Esra A EA; Habib, Amyn A AA
Publication Date: 2021-12-01

Variant appearance in text: EGFR: L792F
PubMed Link: 34853306
Variant Present in the following documents:
  • 41467_2021_27276_MOESM2_ESM.pdf
View BVdb publication page



Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids.

Nature Communications
Gong, Ke K; Guo, Gao G; Beckley, Nicole A NA; Yang, Xiaoyao X; Zhang, Yue Y; Gerber, David E DE; Minna, John D JD; Burma, Sandeep S; Zhao, Dawen D; Akbay, Esra A EA; Habib, Amyn A AA
Publication Date: 2021-12-01

Variant appearance in text: EGFR: L792F
PubMed Link: 34853306
Variant Present in the following documents:
  • 41467_2021_27276_MOESM2_ESM.pdf
View BVdb publication page



Predictive and Prognostic Biomarkers for Lung Cancer Bone Metastasis and Their Therapeutic Value.

Frontiers In Oncology
Chai, Xupeng X; Yinwang, Eloy E; Wang, Zenan Z; Wang, Zhan Z; Xue, Yucheng Y; Li, Binghao B; Zhou, Hao H; Zhang, Wenkan W; Wang, Shengdong S; Zhang, Yongxing Y; Li, Hengyuan H; Mou, Haochen H; Sun, Lingling L; Qu, Hao H; Wang, Fangqian F; Zhang, Zengjie Z; Chen, Tao T; Ye, Zhaoming Z
Publication Date: 2021

Variant appearance in text: EGFR: L792F
PubMed Link: 34722241
Variant Present in the following documents:
  • fonc-11-692788.pdf
View BVdb publication page



High Incidence of C797S Mutation in Patients With Long Treatment History of EGFR Tyrosine Kinase Inhibitors Including Osimertinib.

Jto Clinical And Research Reports
Osoegawa, Atsushi A; Yamaguchi, Masafumi M; Nakamura, Tomomi T; Morinaga, Ryotaro R; Tanaka, Kentaro K; Kashiwabara, Kosuke K; Miura, Takashi T; Suetsugu, Takayuki T; Harada, Taishi T; Asoh, Tatsuma T; Taguchi, Kenichi K; Nabeshima, Kazuki K; Kishimoto, Junji J; Sakai, Kazuko K; Nishio, Kazuto K; Sugio, Kenji K
Publication Date: 2021-07

Variant appearance in text: EGFR: 2374C>T; Leu792Phe
PubMed Link: 34590037
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
View BVdb publication page



Iterative Upgrading of Small Molecular Tyrosine Kinase Inhibitors for EGFR Mutation in NSCLC: Necessity and Perspective.

Pharmaceutics
Zhu, Jing J; Yang, Qian Q; Xu, Weiguo W
Publication Date: 2021-09-18

Variant appearance in text: EGFR: L792F
PubMed Link: 34575576
Variant Present in the following documents:
  • Main text
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (Cambridge (Mass.))
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: L792F
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (New York, N.Y.)
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: L792F
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



A review of research progress on mechanisms and overcoming strategies of acquired osimertinib resistance.

Anti-Cancer Drugs
Qu, Fanjie F; Zhou, Yi Y; Yu, Weiwei W
Publication Date: 2022-01-01

Variant appearance in text: EGFR: L792F
PubMed Link: 34520433
Variant Present in the following documents:
  • acd-33-e76.pdf
View BVdb publication page



A review of research progress on mechanisms and overcoming strategies of acquired osimertinib resistance.

Anti-Cancer Drugs
Qu, Fanjie F; Zhou, Yi Y; Yu, Weiwei W
Publication Date: 2021-09-13

Variant appearance in text: EGFR: L792F
PubMed Link: 34520433
Variant Present in the following documents:
  • acd-33-e76.pdf
View BVdb publication page



NGS-Based ctDNA Profiling After the Resistance of Second-Line Osimertinib for Patient with EGFR-Mutated Pulmonary Adenocarcinoma.

Oncotargets And Therapy
Li, Dan D; Yang, DaFu D; Cui, SaiQiong S; Pan, Evenki E; Yang, Peng P; Dai, ZhaoXia Z
Publication Date: 2021

Variant appearance in text: EGFR: L792F
PubMed Link: 34321891
Variant Present in the following documents:
  • ott-14-4261.pdf
View BVdb publication page



Pan-cancer network disorders revealed by overall and local signaling entropy.

Journal Of Molecular Cell Biology
Feng, Li L; Sun, Yi-Di YD; Li, Chen C; Li, Yi-Xue YX; Chen, Luo-Nan LN; Zeng, Rong R
Publication Date: 2021-12-06

Variant appearance in text: EGFR: L792F
PubMed Link: 34097054
Variant Present in the following documents:
  • mjab031.pdf
View BVdb publication page



Epidermal Growth Factor Receptor Expression and Resistance Patterns to Targeted Therapy in Non-Small Cell Lung Cancer: A Review.

Cells
Karlsen, Emma-Anne EA; Kahler, Sam S; Tefay, Joan J; Joseph, Shannon R SR; Simpson, Fiona F
Publication Date: 2021-05-14

Variant appearance in text: EGFR: L792F
PubMed Link: 34069119
Variant Present in the following documents:
  • Main text
  • cells-10-01206.pdf
View BVdb publication page



Case Report: Dacomitinib May Not Benefit Patients Who Develop Rare Compound Mutations After Later-Line Osimertinib Treatment.

Frontiers In Oncology
Li, Hong-Shuai HS; Yang, Guang-Jian GJ; Wang, Yan Y
Publication Date: 2021

Variant appearance in text: EGFR: L792F
PubMed Link: 33937055
Variant Present in the following documents:
  • Main text
View BVdb publication page



Activity of tarloxotinib-E in cells with EGFR exon-20 insertion mutations and mechanisms of acquired resistance.

Thoracic Cancer
Nishino, Masaya M; Suda, Kenichi K; Koga, Takamasa T; Ohara, Shuta S; Fujino, Toshio T; Soh, Junichi J; Tirunagaru, Vijaya V; Vellanki, Avanish A; Doebele, Robert C RC; Mitsudomi, Tetsuya T
Publication Date: 2021-05

Variant appearance in text: EGFR: L792F
PubMed Link: 33710795
Variant Present in the following documents:
  • Main text
  • TCA-12-1511.pdf
View BVdb publication page



Intercellular transfer of exosomal wild type EGFR triggers osimertinib resistance in non-small cell lung cancer.

Molecular Cancer
Wu, Shaocong S; Luo, Min M; To, Kenneth K W KKW; Zhang, Jianye J; Su, Chaoyue C; Zhang, Hong H; An, Sainan S; Wang, Fang F; Chen, Da D; Fu, Liwu L
Publication Date: 2021-01-18

Variant appearance in text: EGFR: L792F
PubMed Link: 33461557
Variant Present in the following documents:
  • Main text
  • 12943_2021_Article_1307.pdf
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2374C>T; L792F
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Development of EGFR TKIs and Options to Manage Resistance of Third-Generation EGFR TKI Osimertinib: Conventional Ways and Immune Checkpoint Inhibitors.

Frontiers In Oncology
Wu, Leilei L; Ke, Linping L; Zhang, Zhenshan Z; Yu, Jinming J; Meng, Xue X
Publication Date: 2020

Variant appearance in text: EGFR: L792F
PubMed Link: 33392095
Variant Present in the following documents:
  • Main text
  • fonc-10-602762.pdf
View BVdb publication page



Acquired rare recurrent EGFR mutations as mechanisms of resistance to Osimertinib in lung cancer and in silico structural modelling.

American Journal Of Cancer Research
Lin, Lin L; Lu, Qiang Q; Cao, Ran R; Ou, Qiuxiang Q; Ma, Yutong Y; Bao, Hua H; Wu, Xue X; Shao, Yang Y; Wang, Zhaoxia Z; Shen, Bo B
Publication Date: 2020

Variant appearance in text: EGFR: L792F
PubMed Link: 33294282
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical significance of ERBB2 exon 16 skipping: analysis of a real-world retrospective observational cohort study.

Esmo Open
Shi, Lei L; Xu, Caihua C; Ma, Yutong Y; Ou, Qiuxiang Q; Wu, Xue X; Lu, Songhua S; Shao, Yang Y; Guo, Renhua R; Kong, Jinliang J
Publication Date: 2020-11

Variant appearance in text: EGFR: L792F
PubMed Link: 33214226
Variant Present in the following documents:
  • esmoopen-2020-000985.pdf
View BVdb publication page



The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study.

Frontiers In Immunology
Punta, Marco M; Jennings, Victoria A VA; Melcher, Alan A AA; Lise, Stefano S
Publication Date: 2020

Variant appearance in text: EGFR: L792F
PubMed Link: 33133066
Variant Present in the following documents:
  • Table_2.xlsx, sheet 1
  • Table_6.xlsx, sheet 9
  • Table_1.xlsx, sheet 4
  • Table_2.xlsx, sheet 7
  • Table_6.xlsx, sheet 4
  • Table_2.xlsx, sheet 2
  • Table_1.xlsx, sheet 8
View BVdb publication page



[Research Progress of New Generation EGFR-TKIs after Third-generation].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Liu, Yuanyuan Y; Li, Yihui Y; Wang, Jiangong J
Publication Date: 2020-11-20

Variant appearance in text: EGFR: L792F
PubMed Link: 32773008
Variant Present in the following documents:
  • Main text
View BVdb publication page



Status of 10 targeted genes of non-small cell lung cancer in eastern China: A study of 884 patients based on NGS in a single institution.

Thoracic Cancer
Li, Dan D; Ding, Li L; Ran, Wenwen W; Huang, Yan Y; Li, Guangqi G; Wang, Chengqin C; Xiao, Yujing Y; Wang, Xiaonan X; Lin, Dongliang D; Xing, Xiaoming X
Publication Date: 2020-09

Variant appearance in text: EGFR: L792F
PubMed Link: 32729257
Variant Present in the following documents:
  • TCA-11-2580.pdf
View BVdb publication page



The contribution of hereditary cancer-related germline mutations to lung cancer susceptibility.

Translational Lung Cancer Research
Liu, Mengyuan M; Liu, Xinyi X; Suo, Peisu P; Gong, Yuan Y; Qu, Baolin B; Peng, Xiumei X; Xiao, Wenhua W; Li, Yuemin Y; Chen, Yan Y; Zeng, Zhen Z; Lu, Yinying Y; Huang, Tanxiao T; Zhao, Yingshen Y; Liu, Ming M; Li, Lifeng L; Chen, Yaru Y; Zhou, Yanqing Y; Liu, Guifeng G; Yao, Jianfei J; Chen, Shifu S; Song, Lele L
Publication Date: 2020-06

Variant appearance in text: EGFR: L792F
PubMed Link: 32676327
Variant Present in the following documents:
  • Main text
View BVdb publication page



Impact of concurrent genomic alterations in epidermal growth factor receptor (EGFR)-mutated lung cancer.

Journal Of Thoracic Disease
Gini, Beatrice B; Thomas, Nicholas N; Blakely, Collin M CM
Publication Date: 2020-05

Variant appearance in text: EGFR: L792F
PubMed Link: 32642201
Variant Present in the following documents:
  • jtd-12-05-2883.pdf
View BVdb publication page



Genetic Markers in Lung Cancer Diagnosis: A Review.

International Journal Of Molecular Sciences
Wadowska, Katarzyna K; Bil-Lula, Iwona I; Trembecki, Łukasz Ł; Śliwińska-Mossoń, Mariola M
Publication Date: 2020-06-27

Variant appearance in text: EGFR: L792F
PubMed Link: 32604993
Variant Present in the following documents:
  • Main text
  • ijms-21-04569.pdf
View BVdb publication page



Mutant-Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug-Resistant Mutations.

Angewandte Chemie (International Ed. In English)
Jang, Jaebong J; To, Ciric C; De Clercq, Dries J H DJH; Park, Eunyoung E; Ponthier, Charles M CM; Shin, Bo Hee BH; Mushajiang, Mierzhati M; Nowak, Radosław P RP; Fischer, Eric S ES; Eck, Michael J MJ; Jänne, Pasi A PA; Gray, Nathanael S NS
Publication Date: 2020-08-17

Variant appearance in text: EGFR: L792F
PubMed Link: 32510788
Variant Present in the following documents:
  • Main text
View BVdb publication page



Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.

Molecular Cancer
Zhang, Tao T; Qu, Rong R; Chan, Shingpan S; Lai, Mengzhen M; Tong, Linjiang L; Feng, Fang F; Chen, Hongyu H; Song, Tingting T; Song, Peiran P; Bai, Gang G; Liu, Yingqiang Y; Wang, Yanan Y; Li, Yan Y; Su, Yi Y; Shen, Yanyan Y; Sun, Yiming Y; Chen, Yi Y; Geng, Meiyu M; Ding, Ke K; Ding, Jian J; Xie, Hua H
Publication Date: 2020-05-13

Variant appearance in text: EGFR: L792F
PubMed Link: 32404161
Variant Present in the following documents:
  • Main text
View BVdb publication page



Impact and Diagnostic Gaps of Comprehensive Genomic Profiling in Real-World Clinical Practice.

Cancers
Singh, Aditi P AP; Shum, Elaine E; Rajdev, Lakshmi L; Cheng, Haiying H; Goel, Sanjay S; Perez-Soler, Roman R; Halmos, Balazs B
Publication Date: 2020-05-04

Variant appearance in text: EGFR: L792F
PubMed Link: 32375398
Variant Present in the following documents:
  • Main text
View BVdb publication page



[Acquired Drug Resistance Mechanism of Osimertinib in the Targeted Therapy of Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Zhao, Zitong Z; Ni, Yu Y; Li, Li L; Xin, Tao T
Publication Date: 2020-04-20

Variant appearance in text: EGFR: L792F
PubMed Link: 32316715
Variant Present in the following documents:
  • Main text
View BVdb publication page



Secondary Resistant Mutations to Small Molecule Inhibitors in Cancer Cells.

Cancers
Hamid, Abdulaziz B AB; Petreaca, Ruben C RC
Publication Date: 2020-04-09

Variant appearance in text: EGFR: L792F
PubMed Link: 32283832
Variant Present in the following documents:
  • Main text
  • cancers-12-00927.pdf
  • cancers-12-00927-s001.pdf
View BVdb publication page