EGFR c.2389_2390delinsAA ;(p.C797N)

Variant ID: 7-55249091-TG-AA

NM_005228.3(EGFR):c.2389_2390delinsAA;(p.C797N)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer.

Nature Communications
Chmielecki, Juliann J; Gray, Jhanelle E JE; Cheng, Ying Y; Ohe, Yuichiro Y; Imamura, Fumio F; Cho, Byoung Chul BC; Lin, Meng-Chih MC; Majem, Margarita M; Shah, Riyaz R; Rukazenkov, Yuri Y; Todd, Alexander A; Markovets, Aleksandra A; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Ramalingam, Suresh S SS
Publication Date: 2023-02-27

Variant appearance in text: EGFR: C797N
PubMed Link: 36849494
Variant Present in the following documents:
  • Main text
  • 41467_2023_Article_35961.pdf
View BVdb publication page



NSCLC patients with rare EGFR Ex19del/G724S mutation showed good response to afatinib combined with chemotherapy treatment: A two-case report.

Frontiers In Oncology
Wang, Huilin H; Yu, Qitao Q; Shi, Lina L; Hou, Qinhan Q; Dan, Liang L; Liang, Chuqiao C; Hong, Xiaoyu X; Zhao, Yun Y; Ning, Ruiling R
Publication Date: 2022

Variant appearance in text: EGFR: 2389_2390delinsAA; C797N
PubMed Link: 36505860
Variant Present in the following documents:
  • Main text
  • fonc-12-1054593.pdf
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (Cambridge (Mass.))
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: C797N
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (New York, N.Y.)
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: C797N
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Molecular Profiling of Malignant Pleural Effusions with Next Generation Sequencing (NGS): Evidence that Supports Its Role in Cancer Management.

Journal Of Personalized Medicine
Grigoriadou, Georgia Ι GΙ; Esagian, Stepan M SM; Ryu, Han Suk HS; Nikas, Ilias P IP
Publication Date: 2020-11-01

Variant appearance in text: EGFR: C797N
PubMed Link: 33139621
Variant Present in the following documents:
  • Main text
  • jpm-10-00206.pdf
View BVdb publication page



Multiple configurations of EGFR exon 20 resistance mutations after first- and third-generation EGFR TKI treatment affect treatment options in NSCLC.

Plos One
Goldberg, Michael E ME; Montesion, Meagan M; Young, Lauren L; Suh, James J; Greenbowe, Joel J; Kennedy, Mark M; Giaccone, Giuseppe G; Akerley, Wallace L WL; Dowlati, Afshin A; Creelan, Benjamin C BC; Hicks, James K JK; Hesketh, Paul J PJ; Kelly, Karen L KL; Riess, Jonathan W JW; Miller, Vincent A VA; Stephens, Philip J PJ; Frampton, Garrett M GM; Ali, Siraj S; Gregg, Jeffrey P JP; Albacker, Lee A LA
Publication Date: 2018

Variant appearance in text: EGFR: C797N
PubMed Link: 30481207
Variant Present in the following documents:
  • Main text
  • pone.0208097.pdf
View BVdb publication page