Publications:

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Prospective exosome-focused translational research for afatinib (EXTRA) study of patients with nonsmall cell lung cancer harboring EGFR mutation: an observational clinical study.

Therapeutic Advances In Medical Oncology

Takata, Saori S; Morikawa, Kei K; Tanaka, Hisashi H; Itani, Hidetoshi H; Ishihara, Masashi M; Horiuchi, Kazuya K; Kato, Yasuhiro Y; Ikemura, Shinnosuke S; Nakagawa, Hideyuki H; Nakahara, Yoshiro Y; Seki, Yoshitaka Y; Bessho, Akihiro A; Takahashi, Nobumasa N; Hayashi, Kentaro K; Endo, Takeo T; Takeyama, Kiyoshi K; Maekura, Toshiya T; Takigawa, Nagio N; Kawase, Akikazu A; Endoh, Makoto M; Nemoto, Kenji K; Kishi, Kazuma K; Soejima, Kenzo K; Okuma, Yusuke Y; Yoshimura, Kenichi K; Saigusa, Daisuke D; Kanai, Yae Y; Ueda, Koji K; Togashi, Akira A; Matsutani, Noriyuki N; Seki, Nobuhiko N

Publication Date: 2023

Variant appearance in text: EGFR: C797S

PubMed Link: 37323187

Variant Present in the following documents:

• Main text
• 10.1177_17588359231177021.pdf

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PROTACs: A novel strategy for cancer drug discovery and development.

Medcomm

Han, Xin X; Sun, Yi Y

Publication Date: 2023-06

Variant appearance in text: EGFR: C797S

PubMed Link: 37261210

Variant Present in the following documents:

• Main text

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JAC4 Inhibits EGFR-Driven Lung Adenocarcinoma Growth and Metastasis through CTBP1-Mediated JWA/AMPK/NEDD4L/EGFR Axis.

International Journal Of Molecular Sciences

Ding, Kun K; Jiang, Xuqian X; Wang, Zhangding Z; Zou, Lu L; Cui, Jiahua J; Li, Xiong X; Shu, Chuanjun C; Li, Aiping A; Zhou, Jianwei J

Publication Date: 2023-05-15

Variant appearance in text: EGFR: C797S

PubMed Link: 37240137

Variant Present in the following documents:

• Main text
• ijms-24-08794.pdf

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Understanding and targeting resistance mechanisms in cancer.

Medcomm

Lei, Zi-Ning ZN; Tian, Qin Q; Teng, Qiu-Xu QX; Wurpel, John N D JND; Zeng, Leli L; Pan, Yihang Y; Chen, Zhe-Sheng ZS

Publication Date: 2023-06

Variant appearance in text: EGFR: C797S

PubMed Link: 37229486

Variant Present in the following documents:

• Main text
• MCO2-4-e265.pdf

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A retrospective study of postoperative targeted therapy in ALK-positive lung cancer.

Scientific Reports

Wang, Bin B; Song, Yang Y; Chen, Zhuo Z; Su, Xiaona X; Yang, Xin X; Wei, Zhi Z; Chen, Junxia J; Chen, Chuan C; Li, Mengxia M

Publication Date: 2023-05-23

Variant appearance in text: EGFR: C797S

PubMed Link: 37221218

Variant Present in the following documents:

• 41598_2023_Article_34397.pdf

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YAP1 synergize with YY1 transcriptional co-repress DUSP1 to induce osimertinib resistant by activating the EGFR/MAPK pathway and abrogating autophagy in non-small cell lung cancer.

International Journal Of Biological Sciences

Ning, Yue Y; Zheng, Hongmei H; Yang, Yang Y; Zang, Hongjing H; Wang, Weiyuan W; Zhan, Yuting Y; Wang, Haihua H; Luo, Jiadi J; Wen, Qiuyuan Q; Peng, Jinwu J; Xiang, Juanjuan J; Fan, Songqing S

Publication Date: 2023

Variant appearance in text: EGFR: C797S

PubMed Link: 37215986

Variant Present in the following documents:

• ijbsv19p2458.pdf

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'Targeting' Improved Outcomes with Antibody-Drug Conjugates in Non-Small Cell Lung Cancer-An Updated Review.

Current Oncology (Toronto, Ont.)

Verma, Saurav S; Breadner, Daniel D; Raphael, Jacques J

Publication Date: 2023-04-20

Variant appearance in text: EGFR: C797S

PubMed Link: 37185443

Variant Present in the following documents:

• Main text
• curroncol-30-00330.pdf

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Pan-cancer whole-genome comparison of primary and metastatic solid tumours.

Nature

Martínez-Jiménez, Francisco F; Movasati, Ali A; Brunner, Sascha Remy SR; Nguyen, Luan L; Priestley, Peter P; Cuppen, Edwin E; Van Hoeck, Arne A

Publication Date: 2023-05-10

Variant appearance in text: EGFR: C797S

PubMed Link: 37165194

Variant Present in the following documents:

• 41586_2023_6054_MOESM12_ESM.xlsx, sheet 5
• 41586_2023_6054_MOESM3_ESM.pdf
• 41586_2023_6054_MOESM1_ESM.pdf

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Monitoring EGFR-lung cancer evolution: a possible beginning of a "methylation era" in TKI resistance prediction.

Frontiers In Oncology

Fabrizio, Federico Pio FP; Sparaneo, Angelo A; Muscarella, Lucia Anna LA

Publication Date: 2023

Variant appearance in text: EGFR: C797S

PubMed Link: 37152062

Variant Present in the following documents:

• Main text
• fonc-13-1137384.pdf

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The toxicity associated with combining immune check point inhibitors with tyrosine kinase inhibitors in patients with non-small cell lung cancer.

Frontiers In Oncology

Kalra, Anjali A; Rashdan, Sawsan S

Publication Date: 2023

Variant appearance in text: EGFR: C797S

PubMed Link: 37124513

Variant Present in the following documents:

• Main text
• fonc-13-1158417.pdf

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Structure-Activity Relationship Studies Based on Quinazoline Derivatives as EGFR Kinase Inhibitors (2017-Present).

Pharmaceuticals (Basel, Switzerland)

Șandor, Alexandru A; Ionuț, Ioana I; Marc, Gabriel G; Oniga, Ilioara I; Eniu, Dan D; Oniga, Ovidiu O

Publication Date: 2023-04-03

Variant appearance in text: EGFR: C797S

PubMed Link: 37111291

Variant Present in the following documents:

• Main text
• pharmaceuticals-16-00534.pdf

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Challenges of EGFR-TKIs in NSCLC and the potential role of herbs and active compounds: From mechanism to clinical practice.

Frontiers In Pharmacology

Song, Xiaotong X; Cao, Luchang L; Ni, Baoyi B; Wang, Jia J; Qin, Xiaoyan X; Sun, Xiaoyue X; Xu, Bowen B; Wang, Xinmiao X; Li, Jie J

Publication Date: 2023

Variant appearance in text: EGFR: C797S

PubMed Link: 37089959

Variant Present in the following documents:

• Main text
• fphar-14-1090500.pdf

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Genomic landscape and efficacy of HER2-targeted therapy in patients with HER2-mutant non-small cell lung cancer.

Frontiers In Oncology

Han, Yanjie Y; Xiong, Yuanyuan Y; Lu, Tao T; Chen, Rongrong R; Liu, Yuan Y; Tang, Hui H; Geng, Ruixuan R; Wang, Yingyi Y

Publication Date: 2023

Variant appearance in text: EGFR: C797s

PubMed Link: 37077822

Variant Present in the following documents:

• fonc-13-1121708.pdf

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Unbinding Kinetics of Muscarinic M3 Receptor Antagonists Explained by Metadynamics Simulations.

Journal Of Chemical Information And Modeling

Galvani, Francesca F; Pala, Daniele D; Cuzzolin, Alberto A; Scalvini, Laura L; Lodola, Alessio A; Mor, Marco M; Rizzi, Andrea A

Publication Date: 2023-04-13

Variant appearance in text: EGFR: C797S

PubMed Link: 37053454

Variant Present in the following documents:

• ci3c00042.pdf

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Comparison between Three Different Techniques for the Detection of EGFR Mutations in Liquid Biopsies of Patients with Advanced Stage Lung Adenocarcinoma.

International Journal Of Molecular Sciences

Casula, Milena M; Pisano, Marina M; Paliogiannis, Panagiotis P; Colombino, Maria M; Sini, Maria Cristina MC; Zinellu, Angelo A; Santeufemia, Davide D; Manca, Antonella A; Casula, Stefania S; Tore, Silvia S; Lobrano, Renato R; Sardinian Lung Cancer Study Group, ; Cossu, Antonio A; Palmieri, Giuseppe G

Publication Date: 2023-03-29

Variant appearance in text: EGFR: C797S

PubMed Link: 37047382

Variant Present in the following documents:

• Main text
• ijms-24-06410.pdf

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Toward the next generation EGFR inhibitors: an overview of osimertinib resistance mediated by EGFR mutations in non-small cell lung cancer.

Cell Communication And Signaling : Ccs

Li, Yufeng Y; Mao, Tianyu T; Wang, Jing J; Zheng, Hongrui H; Hu, Ziyi Z; Cao, Pingping P; Yang, Suisui S; Zhu, Lingyun L; Guo, Shunyao S; Zhao, Xinfei X; Tian, Yue Y; Shen, Hua H; Lin, Fan F

Publication Date: 2023-04-11

Variant appearance in text: EGFR: C797S

PubMed Link: 37041601

Variant Present in the following documents:

• Main text
• 12964_2023_Article_1082.pdf

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[A Real-world Study on the Expression Characteristics of PD-L1 in Patients 
with Advanced EGFR Positive NSCLC and Its Relationship with the 
Therapeutic Efficacy of EGFR-TKIs].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Chen, Ran R; Gao, Xiang X; Xu, Fudong F; Zhang, Shucai S; Ma, Li L; Hu, Bo B

Publication Date: 2023-03-20

Variant appearance in text: EGFR: C797S

PubMed Link: 37035884

Variant Present in the following documents:

• zgfazz-26-3-217.pdf

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Palladium-Mediated Synthesis of 2-([Biphenyl]-4-yloxy)quinolin-3-carbaldehydes through Suzuki-Miyaura Cross-Coupling and Their in Silico Breast Cancer Studies on the 3ERT Protein.

Acs Omega

Kumar, Peruru Hemanth PH; Rambabu, Majji M; Vijayakumar, Vijayaparthasarathi V; Sarveswari, Sundaramoorthy S

Publication Date: 2023-04-04

Variant appearance in text: EGFR: C797S

PubMed Link: 37033847

Variant Present in the following documents:

• ao2c06418.pdf

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Genomic Landscape of Primary Resistance to Osimertinib Among Hispanic Patients with EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC): Results of an Observational Longitudinal Cohort Study.

Targeted Oncology

Chamorro, Diego F DF; Cardona, Andrés F AF; Rodríguez, July J; Ruiz-Patiño, Alejandro A; Arrieta, Oscar O; Moreno-Pérez, Darwin A DA; Rojas, Leonardo L; Zatarain-Barrón, Zyanya Lucia ZL; Ardila, Dora V DV; Viola, Lucia L; Recondo, Gonzalo G; Blaquier, Juan B JB; Martín, Claudio C; Raez, Luis L; Samtani, Suraj S; Ordóñez-Reyes, Camila C; Garcia-Robledo, Juan Esteban JE; Corrales, Luis L; Sotelo, Carolina C; Ricaurte, Luisa L; Cuello, Mauricio M; Mejía, Sergio S; Jaller, Elvira E; Vargas, Carlos C; Carranza, Hernán H; Otero, Jorge J; Archila, Pilar P; Bermudez, Maritza M; Gamez, Tatiana T; Russo, Alessandro A; Malapelle, Umberto U; de Miguel Perez, Diego D; de Lima, Vladmir C Cordeiro VCC; Freitas, Helano H; Saldahna, Erick E; Rolfo, Christian C; Rosell, Rafael R; ,

Publication Date: 2023-04-05

Variant appearance in text: EGFR: C797S

PubMed Link: 37017806

Variant Present in the following documents:

• Main text
• 11523_2023_Article_955.pdf

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Precision targeted therapy for EGFR mutation-positive NSCLC: Dilemmas and coping strategies.

Thoracic Cancer

Meng, Ying Y; Bai, Rilan R; Cui, Jiuwei J

Publication Date: 2023-04-02

Variant appearance in text: EGFR: C797S

PubMed Link: 37005552

Variant Present in the following documents:

• Main text
• TCA-14-1121.pdf

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Uncommon EGFR-Mutant NSCLC-One Drug Does Not Fit All.

Jto Clinical And Research Reports

Wang, Yang Y; Arulananda, Surein S

Publication Date: 2023-04

Variant appearance in text: EGFR: C797S

PubMed Link: 36994309

Variant Present in the following documents:

• Main text
• main.pdf

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PROTAC'ing oncoproteins: targeted protein degradation for cancer therapy.

Molecular Cancer

Kelm, Jeremy M JM; Pandey, Deepti S DS; Malin, Evan E; Kansou, Hussein H; Arora, Sahil S; Kumar, Raj R; Gavande, Navnath S NS

Publication Date: 2023-03-30

Variant appearance in text: EGFR: C797S

PubMed Link: 36991452

Variant Present in the following documents:

• 12943_2022_Article_1707.pdf

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Dihydrotanshinone I inhibits hepatocellular carcinoma cells proliferation through DNA damage and EGFR pathway.

Peerj

Wang, Linjun L; Xu, Xiangwei X; Chen, Dexing D; Li, Chenghang C

Publication Date: 2023

Variant appearance in text: EGFR: C797S

PubMed Link: 36935927

Variant Present in the following documents:

• Main text
• peerj-11-15022.pdf

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The EGFR C797S Mutation Confers Resistance to a Novel EGFR Inhibitor CLN-081 to EGFR Exon 20 Insertion Mutations.

Jto Clinical And Research Reports

Kagawa, Yosuke Y; Hayashida, Takuma T; Liu, Jie J; Mori, Shunta S; Izumi, Hiroki H; Kumagai, Shogo S; Udagawa, Hibiki H; Hattori, Noboru N; Goto, Koichi K; Kobayashi, Susumu S SS

Publication Date: 2023-03

Variant appearance in text: EGFR: 2390G>C; C797S

PubMed Link: 36915628

Variant Present in the following documents:

• Main text
• main.pdf

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Paired Comparison of Routine Molecular Screening of Patient Samples with Advanced Non-Small Cell Lung Cancer in Circulating Cell-Free DNA Using Three Targeted Assays.

Cancers

Barthelemy, David D; Lescuyer, Gaelle G; Geiguer, Florence F; Grolleau, Emmanuel E; Gauthier, Arnaud A; Balandier, Julie J; Raffin, Margaux M; Bardel, Claire C; Bouyssounouse, Bruno B; Rodriguez-Lafrasse, Claire C; Couraud, Sébastien S; Wozny, Anne-Sophie AS; Payen, Léa L

Publication Date: 2023-03-03

Variant appearance in text: EGFR: C797S

PubMed Link: 36900363

Variant Present in the following documents:

• Main text
• cancers-15-01574.pdf

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Nanotechnology - a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer.

Beilstein Journal Of Nanotechnology

Gorachinov, Filip F; Mraiche, Fatima F; Moustafa, Diala Alhaj DA; Hishari, Ola O; Ismail, Yomna Y; Joseph, Jensa J; Crcarevska, Maja Simonoska MS; Dodov, Marija Glavas MG; Geskovski, Nikola N; Goracinova, Katerina K

Publication Date: 2023

Variant appearance in text: EGFR: C797S

PubMed Link: 36865093

Variant Present in the following documents:

• Beilstein_J_Nanotechnol-14-240.pdf

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: EGFR: C797S

PubMed Link: 36862804

Variant Present in the following documents:

• 1116.pdf
• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6

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Analysis of acquired resistance mechanisms to osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer from the AURA3 trial.

Nature Communications

Chmielecki, Juliann J; Mok, Tony T; Wu, Yi-Long YL; Han, Ji-Youn JY; Ahn, Myung-Ju MJ; Ramalingam, Suresh S SS; John, Thomas T; Okamoto, Isamu I; Yang, James Chih-Hsin JC; Shepherd, Frances A FA; Bulusu, Krishna C KC; Laus, Gianluca G; Collins, Barbara B; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Papadimitrakopoulou, Vassiliki V

Publication Date: 2023-02-27

Variant appearance in text: EGFR: C797S

PubMed Link: 36849516

Variant Present in the following documents:

• 41467_2023_35962_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer.

Nature Communications

Chmielecki, Juliann J; Gray, Jhanelle E JE; Cheng, Ying Y; Ohe, Yuichiro Y; Imamura, Fumio F; Cho, Byoung Chul BC; Lin, Meng-Chih MC; Majem, Margarita M; Shah, Riyaz R; Rukazenkov, Yuri Y; Todd, Alexander A; Markovets, Aleksandra A; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Ramalingam, Suresh S SS

Publication Date: 2023-02-27

Variant appearance in text: EGFR: C797S

PubMed Link: 36849494

Variant Present in the following documents:

• 41467_2023_35961_MOESM3_ESM.xlsx, sheet 1
• 41467_2023_35961_MOESM3_ESM.xlsx, sheet 2

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Current status and future perspectives of bispecific antibodies in the treatment of lung cancer.

Chinese Medical Journal

Wang, Wanying W; Qiu, Tianyu T; Li, Fei F; Ren, Shengxiang S

Publication Date: 2023-02-28

Variant appearance in text: EGFR: C797S

PubMed Link: 36848213

Variant Present in the following documents:

• Main text
• cm9-136-379.pdf

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Pan-cancer clinical impact of latent drivers from double mutations.

Communications Biology

Yavuz, Bengi Ruken BR; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Tuncbag, Nurcan N

Publication Date: 2023-02-20

Variant appearance in text: EGFR: C797S

PubMed Link: 36808143

Variant Present in the following documents:

• Main text
• 42003_2023_4519_MOESM3_ESM.xlsx, sheet 3

View BVdb publication page

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