EGFR c.2417A>G ;(p.K806R)

Variant ID: 7-55249119-A-G

NM_005228.3(EGFR):c.2417A>G;(p.K806R)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-04

Variant appearance in text: EGFR: K806R
PubMed Link: 35304574
Variant Present in the following documents:
  • 41388_2022_Article_2263.pdf
View BVdb publication page



New therapeutic approaches to overcoming resistant EGFR exon 20 alterations.

Critical Reviews In Oncology/Hematology
Li, Alex M AM; Boichard, Amélie A; Felip, Enriqueta E; Kurzrock, Razelle R
Publication Date: 2020-07

Variant appearance in text: EGFR: K806R
PubMed Link: 32485428
Variant Present in the following documents:
  • Main text
View BVdb publication page



ctDNA detected by ddPCR reveals changes in tumour load in metastatic malignant melanoma treated with bevacizumab.

Scientific Reports
Forthun, Rakel Brendsdal RB; Hovland, Randi R; Schuster, Cornelia C; Puntervoll, Hanne H; Brodal, Hans Petter HP; Namløs, Heidi Maria HM; Aasheim, Lars Birger LB; Meza-Zepeda, Leonardo A LA; Gjertsen, Bjørn Tore BT; Knappskog, Stian S; Straume, Oddbjørn O
Publication Date: 2019-11-25

Variant appearance in text: EGFR: K806R
PubMed Link: 31767937
Variant Present in the following documents:
  • 41598_2019_53917_MOESM2_ESM.xlsx, sheet 1
  • 41598_2019_53917_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: K806R
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
View BVdb publication page