Variant ID: 7-55259515-T-G

NM_005228.3(EGFR):c.2573T>G;(p.L858R)

This variant was identified in 6688 publications

View GRCh38 version.




Publications:


EGFR Mutation Status and Subtypes Predicted by CT-Based 3D Radiomic Features in Lung Adenocarcinoma.

Oncotargets And Therapy
Chen, Quan Q; Li, Yan Y; Cheng, Qiguang Q; Van Valkenburgh, Juno J; Sun, Xiaotian X; Zheng, Chuansheng C; Zhang, Ruiguang R; Yuan, Rong R
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35669165
Variant Present in the following documents:
  • Main text
  • ott-15-597.pdf
View BVdb publication page



Cationic copolymers that enhance wild-type-specific suppression in BNA-clamp PCR and preferentially increase the T m of fully matched complementary DNA and BNA strands.

Biology Methods & Protocols
Tachibana, Ami A; Fujimura, Nahohiro N; Takeuchi, Minoru M; Watanabe, Koji K; Teruuchi, Yoko Y; Uchiki, Tomoaki T
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35664806
Variant Present in the following documents:
  • bpac009.pdf
View BVdb publication page



Oligoribonucleotide interference-PCR: principles and applications.

Biology Methods & Protocols
Shimizu, Takeshi T; Fujita, Toshitsugu T; Fujii, Hodaka H
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35664805
Variant Present in the following documents:
  • Main text
  • bpac010.pdf
View BVdb publication page



Anlotinib Downregulates RGC32 Which Provoked by Bevacizumab.

Frontiers In Oncology
Liu, Zhujun Z; Qin, Tingting T; Yuan, Xiaohan X; Yang, Jie J; Shi, Wei W; Zhang, Xiaoling X; Jia, Yanan Y; Liu, Shaochuan S; Wang, Jing J; Li, Kai K
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35664796
Variant Present in the following documents:
  • Main text
View BVdb publication page



Identification of Synergistic Drug Combinations to Target KRAS-Driven Chemoradioresistant Cancers Utilizing Tumoroid Models of Colorectal Adenocarcinoma and Recurrent Glioblastoma.

Frontiers In Oncology
Gupta, Kshama K; Jones, Jeremy C JC; Farias, Virginea De Araujo VA; Mackeyev, Yuri Y; Singh, Pankaj K PK; Quiñones-Hinojosa, Alfredo A; Krishnan, Sunil S
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35664781
Variant Present in the following documents:
  • Table_1.xlsx
View BVdb publication page



A Lung Cancer Patient Harboring a Rare Oncogenic EGFR Exon 20 V786M Mutation Responded to a Third-Generation Tyrosine Kinase Inhibitor: Case Report and Review of the Literature.

Frontiers In Oncology
Zhu, Qi Q; Jiang, Mingyun M; Li, Wenfei W; Sun, Shuangli S; Li, Jisheng J; Stebbing, Justin J; Liang, Xiaodong X; Peng, Ling L
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35664749
Variant Present in the following documents:
  • Main text
  • fonc-12-912426.pdf
View BVdb publication page



Discovery of Anilino-1,4-naphthoquinones as Potent EGFR Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Comprehensive Molecular Modeling.

Acs Omega
Mahalapbutr, Panupong P; Leechaisit, Ronnakorn R; Thongnum, Anusit A; Todsaporn, Duangjai D; Prachayasittikul, Veda V; Rungrotmongkol, Thanyada T; Prachayasittikul, Supaluk S; Ruchirawat, Somsak S; Prachayasittikul, Virapong V; Pingaew, Ratchanok R
Publication Date: 2022-05-31

Variant appearance in text: EGFR: L858R
PubMed Link: 35664590
Variant Present in the following documents:
  • Main text
  • ao2c01188.pdf
View BVdb publication page



Continuous centrifugal microfluidics (CCM) isolates heterogeneous circulating tumor cells via full automation.

Theranostics
Woo, Hyeong Jung HJ; Kim, Seung-Hoon SH; Kang, Hyo Jung HJ; Lee, Soo-Hwan SH; Lee, Seung Joon SJ; Kim, Jong Man JM; Gurel, Ogan O; Kim, Soo Yeol SY; Roh, Hye Ran HR; Lee, Jungmin J; Park, Yeonsoo Y; Shin, Hyun Young HY; Shin, Yong-Il YI; Lee, Sun Min SM; Oh, So Yeon SY; Kim, Young Zoon YZ; Chae, Jung-Il JI; Lee, Seoyoung S; Hong, Min Hee MH; Cho, Byoung Chul BC; Lee, Eun Sook ES; Pantel, Klaus K; Kim, Hye Ryun HR; Kim, Minseok S MS
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35664056
Variant Present in the following documents:
  • thnov12p3676.pdf
  • thnov12p3676s1.pdf
View BVdb publication page



Lung Cancer Biomarker Speak: Teach Me the Language.

Journal Of The Advanced Practitioner In Oncology
Sandy, Beth B; Morrissette, Jennifer J
Publication Date: 2022-04

Variant appearance in text: EGFR: L858R
PubMed Link: 35663172
Variant Present in the following documents:
  • Main text
  • jadpro-13-302.pdf
View BVdb publication page



2020-2021 Drug Updates in Solid Tumors.

Journal Of The Advanced Practitioner In Oncology
Cambareri, Christine C
Publication Date: 2022-04

Variant appearance in text: EGFR: L858R
PubMed Link: 35663163
Variant Present in the following documents:
  • Main text
  • jadpro-13-275.pdf
View BVdb publication page



Leveraging Bulk and Single-Cell RNA Sequencing Data of NSCLC Tumor Microenvironment and Therapeutic Potential of NLOC-15A, A Novel Multi-Target Small Molecule.

Frontiers In Immunology
Lawal, Bashir B; Wu, Alexander T H ATH; Huang, Hsu-Shan HS
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35655775
Variant Present in the following documents:
  • Main text
  • fimmu-13-872470.pdf
View BVdb publication page



Osimertinib for lung cancer cells harboring low-frequency EGFR T790M mutation.

Translational Oncology
Joshi, Asim A; Butle, Ashwin A; Hait, Supriya S; Mishra, Rohit R; Trivedi, Vaishakhi V; Thorat, Rahul R; Choughule, Anuradha A; Noronha, Vanita V; Prabhash, Kumar K; Dutt, Amit A
Publication Date: 2022-05-30

Variant appearance in text: EGFR: L858R
PubMed Link: 35653897
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Cancer Metastases from Lung Adenocarcinoma Disappeared After Molecular Targeted Therapy: A Successfully Clinical Treatment Experience.

Pharmacogenomics And Personalized Medicine
Li, Meng-Jie MJ; Wei, Jun J; Ai, Guo-Ping GP; Liu, Ying Y; Zhu, Jian J
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35651533
Variant Present in the following documents:
  • Main text
  • pgpm-15-539.pdf
View BVdb publication page



Acute Onset of a Life-Threatening Skin Toxicity Due to Osimertinib: Severe Psoriasis Versus Toxic Epidermal Necrolysis.

Cureus
Rittberg, Rebekah R; Ho, Cheryl C; Wang, Ying Y
Publication Date: 2022-04

Variant appearance in text: EGFR: L858R
PubMed Link: 35651371
Variant Present in the following documents:
  • Main text
  • cureus-0014-00000024513.pdf
View BVdb publication page



Efficacy of osimertinib in epidermal growth factor receptor-mutated non-small-cell lung cancer patients with pleural effusion.

Bmc Cancer
Nokihara, Hiroshi H; Ogino, Hirokazu H; Mitsuhashi, Atsushi A; Kondo, Kensuke K; Ogawa, Ei E; Ozaki, Ryohiko R; Yabuki, Yohei Y; Yoneda, Hiroto H; Otsuka, Kenji K; Nishioka, Yasuhiko Y
Publication Date: 2022-06-01

Variant appearance in text: EGFR: L858R
PubMed Link: 35650550
Variant Present in the following documents:
  • Main text
  • 12885_2022_Article_9701.pdf
View BVdb publication page



Circulating cell-free DNA for cancer early detection.

Innovation (Cambridge (Mass.))
Gao, Qiang Q; Zeng, Qiang Q; Wang, Zhijie Z; Li, Chengcheng C; Xu, Yu Y; Cui, Peng P; Zhu, Xin X; Lu, Huafei H; Wang, Guoqiang G; Cai, Shangli S; Wang, Jie J; Fan, Jia J
Publication Date: 2022-07-12

Variant appearance in text: EGFR: L858R
PubMed Link: 35647572
Variant Present in the following documents:
  • Main text
View BVdb publication page



Development of small molecule extracellular signal-regulated kinases (ERKs) inhibitors for cancer therapy.

Acta Pharmaceutica Sinica. B
Pan, Xiaoli X; Pei, Junping J; Wang, Aoxue A; Shuai, Wen W; Feng, Lu L; Bu, Faqian F; Zhu, Yumeng Y; Zhang, Lan L; Wang, Guan G; Ouyang, Liang L
Publication Date: 2022-05

Variant appearance in text: EGFR: L858R
PubMed Link: 35646548
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Characteristics of Genomic Alterations in Pericardial Effusion of Advanced Non-small Cell Lung Cancer.

Frontiers In Genetics
He, Jiaxue J; Hu, Xintong X; Chen, Liguo L; Liu, Qiaoliang Q; Jiang, Yanfang Y
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35646096
Variant Present in the following documents:
  • Main text
  • fgene-13-850290.pdf
View BVdb publication page



TROY Modulates Cancer Stem-Like Cell Properties and Gefitinib Resistance Through EMT Signaling in Non-Small Cell Lung Cancer.

Frontiers In Genetics
Wu, Linying L; Yu, Yuman Y; Xu, Liming L; Wang, Xiaoling X; Zhou, Jianying J; Wang, Yuehong Y
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35646083
Variant Present in the following documents:
  • Main text
  • fgene-13-881875.pdf
View BVdb publication page



Subsequent treatments beyond progression on osimertinib in EGFR-mutated NSCLC and leptomeningeal metastases.

Bmc Medicine
Zheng, Mei-Mei MM; Li, Yang-Si YS; Tu, Hai-Yan HY; Sun, Hao H; Yin, Kai K; Jiang, Ben-Yuan BY; Yang, Jin-Ji JJ; Zhang, Xu-Chao XC; Zhou, Qing Q; Xu, Chong-Rui CR; Wang, Zhen Z; Chen, Hua-Jun HJ; Zhou, De-Xiang DX; Wu, Yi-Long YL
Publication Date: 2022-05-30

Variant appearance in text: EGFR: L858R
PubMed Link: 35644609
Variant Present in the following documents:
  • Main text
  • 12916_2022_Article_2387.pdf
View BVdb publication page



AXL/CDCP1/SRC axis confers acquired resistance to osimertinib in lung cancer.

Scientific Reports
Murakami, Yuichi Y; Kusakabe, Daiki D; Watari, Kosuke K; Kawahara, Akihiko A; Azuma, Koichi K; Akiba, Jun J; Taniguchi, Masahiko M; Kuwano, Michihiko M; Ono, Mayumi M
Publication Date: 2022-05-28

Variant appearance in text: EGFR: L858R
PubMed Link: 35643725
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_12995.pdf
View BVdb publication page



Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib.

Bmc Cancer
Jin, Ying Y; Lin, Chen C; Shi, Xun X; He, Qiong Q; Yan, Junrong J; Yu, Xinmin X; Chen, Ming M
Publication Date: 2022-05-28

Variant appearance in text: EGFR: L858R
PubMed Link: 35643428
Variant Present in the following documents:
  • Main text
  • 12885_2022_Article_9683.pdf
View BVdb publication page



Comprehensive Characterization of the Genomic Landscape in Chinese Pulmonary Neuroendocrine Tumors Reveals Prognostic and Therapeutic Markers (CSWOG-1901).

The Oncologist
Peng, Wenying W; Cao, Liming L; Chen, Likun L; Lin, Gen G; Zhu, Bo B; Hu, Xiaohua X; Lin, Yingcheng Y; Zhang, Sheng S; Jiang, Meilin M; Wang, Jingyi J; Li, Junjun J; Li, Chao C; Shao, Lin L; Du, Haiwei H; Hou, Ting T; Chen, Zhiqiu Z; Xiang, Jianxing J; Pu, Xingxiang X; Li, Jia J; Xu, Fang F; Loong, Herbert H; Wu, Lin L
Publication Date: 2022-03-04

Variant appearance in text: EGFR: L858R
PubMed Link: 35641209
Variant Present in the following documents:
  • Main text
  • oyab044.pdf
View BVdb publication page



High-Dose Osimertinib for CNS Progression in EGFR+ NSCLC: A Multi-Institutional Experience.

Jto Clinical And Research Reports
Piper-Vallillo, A J AJ; Rotow, Julia K JK; Aredo, Jacqueline V JV; Shaverdashvili, Khvaramze K; Luo, Jia J; Carlisle, Jennifer W JW; Husain, Hatim H; Muzikansky, Alona A; Heist, Rebecca S RS; Rangachari, Deepa D; Ramalingam, Suresh S SS; Wakelee, Heather A HA; Yu, Helena A HA; Sequist, Lecia V LV; Bauml, Joshua M JM; Neal, Joel W JW; Piotrowska, Zofia Z
Publication Date: 2022-06

Variant appearance in text: EGFR: L858R
PubMed Link: 35637759
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



FFPE-Based NGS Approaches into Clinical Practice: The Limits of Glory from a Pathologist Viewpoint.

Journal Of Personalized Medicine
Cappello, Filippo F; Angerilli, Valentina V; Munari, Giada G; Ceccon, Carlotta C; Sabbadin, Marianna M; Pagni, Fabio F; Fusco, Nicola N; Malapelle, Umberto U; Fassan, Matteo M
Publication Date: 2022-05-05

Variant appearance in text: EGFR: L858R
PubMed Link: 35629172
Variant Present in the following documents:
  • Main text
  • jpm-12-00750.pdf
View BVdb publication page



A Single-Institute Experience with C-ros Oncogene 1 Translocation in Non-Small Cell Lung Cancers in Taiwan.

International Journal Of Molecular Sciences
Wang, Hsiang-Sheng HS; Liu, Chien-Ying CY; Hsu, Sheng-Chi SC; Huang, Shih-Chiang SC; Hung, Tsai-Hsien TH; Ng, Kwai-Fong KF; Chen, Tse-Ching TC
Publication Date: 2022-05-21

Variant appearance in text: EGFR: L858R
PubMed Link: 35628598
Variant Present in the following documents:
  • Main text
  • ijms-23-05789.pdf
View BVdb publication page



Combination Strategies Involving Immune Checkpoint Inhibitors and Tyrosine Kinase or BRAF Inhibitors in Aggressive Thyroid Cancer.

International Journal Of Molecular Sciences
Ragusa, Francesca F; Ferrari, Silvia Martina SM; Elia, Giusy G; Paparo, Sabrina Rosaria SR; Balestri, Eugenia E; Botrini, Chiara C; Patrizio, Armando A; Mazzi, Valeria V; Guglielmi, Giovanni G; Foddis, Rudy R; Spinelli, Claudio C; Ulisse, Salvatore S; Antonelli, Alessandro A; Fallahi, Poupak P
Publication Date: 2022-05-20

Variant appearance in text: EGFR: L858R
PubMed Link: 35628540
Variant Present in the following documents:
  • Main text
  • ijms-23-05731.pdf
View BVdb publication page



Mediating EGFR-TKI Resistance by VEGF/VEGFR Autocrine Pathway in Non-Small Cell Lung Cancer.

Cells
Osude, Chike C; Lin, Leo L; Patel, Meet M; Eckburg, Adam A; Berei, Joseph J; Kuckovic, Adijan A; Dube, Namrata N; Rastogi, Aayush A; Gautam, Shruti S; Smith, Thomas J TJ; Sreenivassappa, Shylendra B SB; Puri, Neelu N
Publication Date: 2022-05-19

Variant appearance in text: EGFR: L858R
PubMed Link: 35626731
Variant Present in the following documents:
  • Main text
  • cells-11-01694.pdf
View BVdb publication page



Treatment Strategies for Non-Small Cell Lung Cancer Harboring Common and Uncommon EGFR Mutations: Drug Sensitivity Based on Exon Classification, and Structure-Function Analysis.

Cancers
Kitadai, Rui R; Okuma, Yusuke Y
Publication Date: 2022-05-20

Variant appearance in text: EGFR: L858R
PubMed Link: 35626123
Variant Present in the following documents:
  • Main text
  • cancers-14-02519.pdf
View BVdb publication page



Wide Next-Generation Sequencing Characterization of Young Adults Non-Small-Cell Lung Cancer Patients.

Cancers
Ulivi, Paola P; Urbini, Milena M; Petracci, Elisabetta E; Canale, Matteo M; Dubini, Alessandra A; Bartolini, Daniela D; Calistri, Daniele D; Cravero, Paola P; Fonzi, Eugenio E; Martinelli, Giovanni G; Priano, Ilaria I; Andrikou, Kalliopi K; Bronte, Giuseppe G; Crinò, Lucio L; Delmonte, Angelo A
Publication Date: 2022-05-10

Variant appearance in text: EGFR: L858R
PubMed Link: 35625958
Variant Present in the following documents:
  • Main text
  • cancers-14-02352.pdf
View BVdb publication page



Predicting EGFR mutation, ALK rearrangement, and uncommon EGFR mutation in NSCLC patients by driverless artificial intelligence: a cohort study.

Respiratory Research
Tan, Xueyun X; Li, Yuan Y; Wang, Sufei S; Xia, Hui H; Meng, Rui R; Xu, Juanjuan J; Duan, Yanran Y; Li, Yan Y; Yang, Guanghai G; Ma, Yanling Y; Jin, Yang Y
Publication Date: 2022-05-27

Variant appearance in text: EGFR: L858R
PubMed Link: 35624472
Variant Present in the following documents:
  • Main text
  • 12931_2022_Article_2053.pdf
View BVdb publication page



HRAS Q61L Mutation as a Possible Target for Non-Small Cell Lung Cancer: Case Series and Review of Literature.

Current Oncology (Toronto, Ont.)
Mathiot, Laurent L; Herbreteau, Guillaume G; Robin, Siméon S; Fenat, Charlotte C; Bennouna, Jaafar J; Blanquart, Christophe C; Denis, Marc M; Pons-Tostivint, Elvire E
Publication Date: 2022-05-20

Variant appearance in text: EGFR: Leu858Arg
PubMed Link: 35621690
Variant Present in the following documents:
  • Main text
  • curroncol-29-00300.pdf
View BVdb publication page



Efficacy of Osimertinib in Lung Squamous Cell Carcinoma Patients with EGFR Gene Mutation-Case Report and a Literature Review.

Current Oncology (Toronto, Ont.)
Rekowska, Anna A; Rola, Piotr P; Wójcik-Superczyńska, Magdalena M; Chmielewska, Izabela I; Krawczyk, Paweł P; Milanowski, Janusz J
Publication Date: 2022-05-13

Variant appearance in text: EGFR: L858R
PubMed Link: 35621675
Variant Present in the following documents:
  • Main text
  • curroncol-29-00285.pdf
View BVdb publication page



Understanding the P-Loop Conformation in the Determination of Inhibitor Selectivity Toward the Hepatocellular Carcinoma-Associated Dark Kinase STK17B.

Frontiers In Molecular Biosciences
Liu, Chang C; Li, Zhizhen Z; Liu, Zonghan Z; Yang, Shiye S; Wang, Qing Q; Chai, Zongtao Z
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35620482
Variant Present in the following documents:
  • fmolb-09-901603.pdf
View BVdb publication page



CRISPER/CAS System, a Novel Tool of Targeted Therapy of Drug-Resistant Lung Cancer.

Advanced Pharmaceutical Bulletin
Akbari Kordkheyli, Vahid V; Rashidi, Mohsen M; Shokri, Yasaman Y; Fallahpour, Samane S; Variji, Atena A; Nabipour Ghara, Ehsan E; Hosseini, Sayed Mostafa SM
Publication Date: 2022-03

Variant appearance in text: EGFR: L858R
PubMed Link: 35620343
Variant Present in the following documents:
  • Main text
  • apb-12-262.pdf
View BVdb publication page



Application and Prospect of CRISPR/Cas9 Technology in Reversing Drug Resistance of Non-Small Cell Lung Cancer.

Frontiers In Pharmacology
Huang, Lu L; Liao, Zhi Z; Liu, Zhixi Z; Chen, Yan Y; Huang, Tingwenli T; Xiao, Hongtao H
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35620280
Variant Present in the following documents:
  • Main text
  • fphar-13-900825.pdf
View BVdb publication page



Genomic Alteration Spectrum of Non-Small Cell Lung Cancer Patients in East-China Characterized by Tumor Tissue DNA and Cell-Free DNA.

Oncotargets And Therapy
Li, Jie J; Chen, Siwen S; Xue, Hui H; Wang, Haoyi H; Huang, Tianwei T; Xie, Hongya H; He, Jiang J; Ke, Cai C; Yu, Zhaonan Z; Ni, Bin B
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35615557
Variant Present in the following documents:
  • Main text
  • ott-15-571.pdf
View BVdb publication page



Gene alternation of cerebrospinal fluid in patients with leptomeningeal metastases of lung adenocarcinoma using next-generation sequencing.

Bmc Cancer
Yang, Hainan H; Wen, Lei L; Pan, Yingying Y; Shan, Changguo C; Hong, Weiping W; Wang, Hui H; Zhou, Cheng C; Cai, Linbo L; Zhou, Caicun C
Publication Date: 2022-05-25

Variant appearance in text: EGFR: L858R
PubMed Link: 35614407
Variant Present in the following documents:
  • Main text
  • 12885_2022_Article_9597.pdf
View BVdb publication page



Pyronaridine Protects against SARS-CoV-2 Infection in Mouse.

Acs Infectious Diseases
Puhl, Ana C AC; Gomes, Giovanni F GF; Damasceno, Samara S; Godoy, Andre S AS; Noske, Gabriela D GD; Nakamura, Aline M AM; Gawriljuk, Victor O VO; Fernandes, Rafaela S RS; Monakhova, Natalia N; Riabova, Olga O; Lane, Thomas R TR; Makarov, Vadim V; Veras, Flavio P FP; Batah, Sabrina S SS; Fabro, Alexandre T AT; Oliva, Glaucius G; Cunha, Fernando Q FQ; Alves-Filho, José C JC; Cunha, Thiago M TM; Ekins, Sean S
Publication Date: 2022-05-24

Variant appearance in text: EGFR: L858R
PubMed Link: 35609344
Variant Present in the following documents:
  • id2c00091_si_001.pdf
View BVdb publication page



Evaluating the Efficacy of EGFR-TKIs Combined With Radiotherapy in Advanced Lung Adenocarcinoma Patients With EGFR Mutation: A Retrospective Study.

Technology In Cancer Research & Treatment
Wang, Yuxiang Y; Yu, Wenjuan W; Shi, Jian J; Qiu, Rong R; Jiang, Nan N; Wang, Zhuofan Z; Yang, Jie J; Jia, Zhongfei Z; Song, Meng M
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35607295
Variant Present in the following documents:
  • Main text
  • 10.1177_15330338221100358.pdf
View BVdb publication page



Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society
Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW
Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2573T>G; Leu858Arg
PubMed Link: 35606799
Variant Present in the following documents:
  • Main text
  • 41021_2022_Article_248.pdf
  • 41021_2022_248_MOESM1_ESM.xlsx
View BVdb publication page



When to add anti-angiogenesis drugs to EGFR-mutated metastatic non-small cell lung cancer patients: a real-world study from Taiwan.

Bmc Cancer
Chen, Chieh-Lung CL; Wang, Sing-Ting ST; Liao, Wei-Chih WC; Chen, Chia-Hung CH; Tu, Chih-Yen CY; Chen, Hung-Jen HJ; Hsia, Te-Chun TC; Cheng, Wen-Chien WC
Publication Date: 2022-05-23

Variant appearance in text: EGFR: L858R
PubMed Link: 35599308
Variant Present in the following documents:
  • Main text
  • 12885_2022_Article_9672.pdf
View BVdb publication page



[Advances in Treatment of Non-small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Yang, Xue X; Zhao, Jun J
Publication Date: 2022-05-20

Variant appearance in text: EGFR: L858R
PubMed Link: 35599009
Variant Present in the following documents:
  • Main text
  • zgfazz-25-5-337.pdf
View BVdb publication page



Recent advances in IAP-based PROTACs (SNIPERs) as potential therapeutic agents.

Journal Of Enzyme Inhibition And Medicinal Chemistry
Wang, Chao C; Zhang, Yujing Y; Shi, Lingyu L; Yang, Shanbo S; Chang, Jing J; Zhong, Yingjie Y; Li, Qian Q; Xing, Dongming D
Publication Date: 2022-12

Variant appearance in text: EGFR: L858R
PubMed Link: 35589670
Variant Present in the following documents:
  • Main text
View BVdb publication page



Results of screening in early and advanced thoracic malignancies in the EORTC pan-European SPECTAlung platform.

Scientific Reports
Morfouace, M M; Novello, S S; Stevovic, A A; Dooms, C C; Janžič, U U; Berghmans, T T; Dziadziuszko, R R; Gorlia, T T; Felip, E E; Paz-Ares, L L; Mazieres, J J; O'Brien, M M; Bironzo, P P; Vansteenkiste, J J; Lacroix, L L; Dingemans, A C AC; Golfinopoulos, V V; Besse, B B
Publication Date: 2022-05-18

Variant appearance in text: EGFR: L858R
PubMed Link: 35585228
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_12056.pdf
View BVdb publication page



Non-small cell lung cancer-small cell lung cancer transformation as mechanism of resistance to tyrosine kinase inhibitors in lung cancer.

Cancer Drug Resistance (Alhambra, Calif.)
Rath, Barbara B; Plangger, Adelina A; Hamilton, Gerhard G
Publication Date: 2020

Variant appearance in text: EGFR: L858R
PubMed Link: 35582610
Variant Present in the following documents:
  • cdr-3-171.pdf
View BVdb publication page



Involvement of SNX1 in regulating EGFR endocytosis in a gefitinib-resistant NSCLC cell lines.

Cancer Drug Resistance (Alhambra, Calif.)
Nishimura, Yukio Y; Itoh, Kazuyuki K
Publication Date: 2019

Variant appearance in text: EGFR: L858R
PubMed Link: 35582586
Variant Present in the following documents:
  • cdr-2-539.pdf
View BVdb publication page



Longitudinal monitoring for the emergence of epidermal growth factor C797S resistance mutations in non-small cell lung cancer using blood-based droplet digital PCR.

Cancer Drug Resistance (Alhambra, Calif.)
Bowling, Mark M; Arastu, Hyder H; Edwards, Victoria V; Jackson, Leisa L; Thurston, Scott S; Reese, Jordan J; Mellert, Hestia H; Pestano, Gary G; Walker, Paul P
Publication Date: 2019

Variant appearance in text: EGFR: L858R
PubMed Link: 35582570
Variant Present in the following documents:
  • cdr-2-912.pdf
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Efficacy of ICIs on patients with oncogene-driven non-small cell lung cancer: a retrospective study.

Cancer Drug Resistance (Alhambra, Calif.)
Guo, Xiaojin X; Du, He H; Li, Jiayu J; Yang, Menghang M; Xiong, Anweng A; Zhang, Haiping H; Wu, Fengying F
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35582532
Variant Present in the following documents:
  • cdr-5-15.pdf
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RET kinase alterations in targeted cancer therapy.

Cancer Drug Resistance (Alhambra, Calif.)
Liu, Xuan X; Hu, Xueqing X; Shen, Tao T; Li, Qi Q; Mooers, Blaine H M BHM; Wu, Jie J
Publication Date: 2020

Variant appearance in text: EGFR: L858R
PubMed Link: 35582449
Variant Present in the following documents:
  • cdr-3-472.pdf
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The aqueous extract of brucea javanica reduces tumorigenicity of human lung cancer tumorspheres.

Cancer Drug Resistance (Alhambra, Calif.)
Kim, Seung-Hun SH; Fan, Po-Wei PW; Hsieh, Chang-Heng CH; Lin, Hsuan-Yuan HY; Wang, Wen-Hsin WH; Lee, Ming-Chung MC; Fang, Kang K
Publication Date: 2021

Variant appearance in text: EGFR: L858R
PubMed Link: 35582384
Variant Present in the following documents:
  • cdr-4-866.pdf
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EGFR/BRAF/MEK co-inhibition for EGFR-mutated lung adenocarcinoma patients with an acquired BRAFV600E mutation: a case report and review of literature.

Cancer Drug Resistance (Alhambra, Calif.)
Zeng, Ran R; Luo, Lifeng L; Sun, Xianwen X; Bao, Zhiyao Z; Du, Wei W; Dai, Ranran R; Tang, Wei W; Gao, Beili B; Xiang, Yi Y
Publication Date: 2021

Variant appearance in text: EGFR: L858R
PubMed Link: 35582379
Variant Present in the following documents:
  • cdr-4-1019.pdf
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Liquid biopsy in metastatic breast cancer.

Cancer Drug Resistance (Alhambra, Calif.)
Banys-Paluchowski, Malgorzata M; Paluchowski, Peter P
Publication Date: 2019

Variant appearance in text: EGFR: L858R
PubMed Link: 35582275
Variant Present in the following documents:
  • cdr-2-1062.pdf
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Attribution of Cancer Origins to Endogenous, Exogenous, and Preventable Mutational Processes.

Molecular Biology And Evolution
Cannataro, Vincent L VL; Mandell, Jeffrey D JD; Townsend, Jeffrey P JP
Publication Date: 2022-05-03

Variant appearance in text: EGFR: L858R
PubMed Link: 35580068
Variant Present in the following documents:
  • msac084.pdf
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Machine Learning-Based Radiomics for Prediction of Epidermal Growth Factor Receptor Mutations in Lung Adenocarcinoma.

Disease Markers
Lu, Jiameng J; Ji, Xiaoqing X; Wang, Lixia L; Jiang, Yunxiu Y; Liu, Xinyi X; Ma, Zhenshen Z; Ning, Yafei Y; Dong, Jie J; Peng, Haiying H; Sun, Fei F; Guo, Zihan Z; Ji, Yanbo Y; Xing, Jianping J; Lu, Yue Y; Lu, Degan D
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35578691
Variant Present in the following documents:
  • DM2022-2056837.pdf
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Constituents from ripe figs of Ficus vallis-choudae Delile (Moraceae) with antiplasmodial activity.

Parasitology Research
Chouna, Hardo Suzy Donfack HSD; Dize, Darline D; Kagho, Donald Ulrich Kenou DUK; Bankeu, Jean Jules Kezetas JJK; Fongang, Yannick Stéphane Fotsing YSF; Tali, Mariscal Brice Tchatat MBT; Ponou, Beaudelaire Kemvoufo BK; Bitchagno, Gabin Thierry Mbahbou GTM; Awantu, Angelbert Fusi AF; Tapondjou, Léon Azefack LA; Lenta, Bruno Ndjakou BN; Fekam, Fabrice Boyom FB; Sewald, Norbert N; Ngouela, Silvère Augustin SA
Publication Date: 2022-05-17

Variant appearance in text: EGFR: L858R
PubMed Link: 35578036
Variant Present in the following documents:
  • 436_2022_Article_7540.pdf
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Development of a Nomogram Based on 3D CT Radiomics Signature to Predict the Mutation Status of EGFR Molecular Subtypes in Lung Adenocarcinoma: A Multicenter Study.

Frontiers In Oncology
Zhang, Guojin G; Deng, Liangna L; Zhang, Jing J; Cao, Yuntai Y; Li, Shenglin S; Ren, Jialiang J; Qian, Rong R; Peng, Shengkun S; Zhang, Xiaodi X; Zhou, Junlin J; Zhang, Zhuoli Z; Kong, Weifang W; Pu, Hong H
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35574401
Variant Present in the following documents:
  • fonc-12-889293.pdf
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Afatinib for the Treatment of Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations: An Updated Database of 1023 Cases Brief Report.

Frontiers In Oncology
Yang, James Chih-Hsin JC; Schuler, Martin M; Popat, Sanjay S; Miura, Satoru S; Park, Keunchil K; Passaro, Antonio A; De Marinis, Filippo F; Solca, Flavio F; Märten, Angela A; Kim, Edward S ES
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35574304
Variant Present in the following documents:
  • fonc-12-834704.pdf
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Dual-Targeted Therapy Circumvents Non-Genetic Drug Resistance to Targeted Therapy.

Frontiers In Oncology
Wang, Wei W; Sun, Yue Y; Liu, Xiaobo X; Kumar, Shaji K SK; Jin, Fengyan F; Dai, Yun Y
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35574302
Variant Present in the following documents:
  • fonc-12-859455.pdf
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The Tumor Suppressor Kinase LKB1: Metabolic Nexus.

Frontiers In Cell And Developmental Biology
Bourouh, Mohammed M; Marignani, Paola A PA
Publication Date: 2022

Variant appearance in text: EGFR: L858R
PubMed Link: 35573694
Variant Present in the following documents:
  • fcell-10-881297.pdf
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