EGFR c.2573T>G ;(p.L858R)

Variant ID: 7-55259515-T-G

NM_005228.3(EGFR):c.2573T>G;(p.L858R)

This variant was identified in 6663 publications

View GRCh38 version.




Publications:


Phase 1b trial of anti-EGFR antibody JMT101 and Osimertinib in EGFR exon 20 insertion-positive non-small-cell lung cancer.

Nature Communications
Zhao, Shen S; Zhuang, Wu W; Han, Baohui B; Song, Zhengbo Z; Guo, Wei W; Luo, Feng F; Wu, Lin L; Hu, Yi Y; Wang, Huijuan H; Dong, Xiaorong X; Jiang, Da D; Wang, Mingxia M; Miao, Liyun L; Wang, Qian Q; Zhang, Junping J; Fu, Zhenming Z; Huang, Yihua Y; Xu, Chunwei C; Hu, Longyu L; Li, Lei L; Hu, Rong R; Yang, Yang Y; Li, Mengke M; Yang, Xiugao X; Zhang, Li L; Huang, Yan Y; Fang, Wenfeng W
Publication Date: 2023-06-12

Variant appearance in text: EGFR: 2573T>G; L858R
PubMed Link: 37308490
Variant Present in the following documents:
  • 41467_2023_39139_MOESM4_ESM.xlsx, sheet 3
View BVdb publication page



Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway.

Nature Communications
González, Lorena L; Díaz, Lucía L; Pous, Joan J; Baginski, Blazej B; Duran-Corbera, Anna A; Scarpa, Margherita M; Brun-Heath, Isabelle I; Igea, Ana A; Martin-Malpartida, Pau P; Ruiz, Lidia L; Pallara, Chiara C; Esguerra, Mauricio M; Colizzi, Francesco F; Mayor-Ruiz, Cristina C; Biondi, Ricardo M RM; Soliva, Robert R; Macias, Maria J MJ; Orozco, Modesto M; Nebreda, Angel R AR
Publication Date: 2023-06-12

Variant appearance in text: EGFR: L858R
PubMed Link: 37308482
Variant Present in the following documents:
  • 41467_2023_39051_MOESM3_ESM.xlsx, sheet 5
View BVdb publication page



PROTACs: A novel strategy for cancer drug discovery and development.

Medcomm
Han, Xin X; Sun, Yi Y
Publication Date: 2023-06

Variant appearance in text: EGFR: L858R
PubMed Link: 37261210
Variant Present in the following documents:
  • Main text
  • MCO2-4-e290.pdf
View BVdb publication page



From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia.

Nature Communications
Saez-Ayala, Magali M; Hoffer, Laurent L; Abel, Sébastien S; Ben Yaala, Khaoula K; Sicard, Benoit B; Andrieu, Guillaume P GP; Latiri, Mehdi M; Davison, Emma K EK; Ciufolini, Marco A MA; Brémond, Paul P; Rebuffet, Etienne E; Roche, Philippe P; Derviaux, Carine C; Voisset, Edwige E; Montersino, Camille C; Castellano, Remy R; Collette, Yves Y; Asnafi, Vahid V; Betzi, Stéphane S; Dubreuil, Patrice P; Combes, Sébastien S; Morelli, Xavier X
Publication Date: 2023-05-29

Variant appearance in text: EGFR: L858R
PubMed Link: 37248212
Variant Present in the following documents:
  • 41467_2023_38668_MOESM1_ESM.pdf
View BVdb publication page



Glucolipotoxic Stress-Induced Mig6 Desensitizes EGFR Signaling and Promotes Pancreatic Beta Cell Death.

Metabolites
Chen, Yi-Chun YC; Lutkewitte, Andrew J AJ; Basavarajappa, Halesha D HD; Fueger, Patrick T PT
Publication Date: 2023-05-04

Variant appearance in text: EGFR: L858R
PubMed Link: 37233668
Variant Present in the following documents:
  • metabolites-13-00627.pdf
View BVdb publication page



Non-canonical integrin signaling activates EGFR and RAS-MAPK-ERK signaling in small cell lung cancer.

Theranostics
Rubio, Karla K; Romero-Olmedo, Addi J AJ; Sarvari, Pouya P; Swaminathan, Guruprasadh G; Ranvir, Vikas P VP; Rogel-Ayala, Diana G DG; Cordero, Julio J; Günther, Stefan S; Mehta, Aditi A; Bassaly, Birgit B; Braubach, Peter P; Wygrecka, Malgorzata M; Gattenlöhner, Stefan S; Tresch, Achim A; Braun, Thomas T; Dobreva, Gergana G; Rivera, Miguel N MN; Singh, Indrabahadur I; Graumann, Johannes J; Barreto, Guillermo G
Publication Date: 2023

Variant appearance in text: EGFR: L858R
PubMed Link: 37215577
Variant Present in the following documents:
  • thnov13p2384.pdf
View BVdb publication page



Identification of FKBP10 prognostic value in lung adenocarcinoma patients with surgical resection of brain metastases: A retrospective single-institution cohort study.

Clinics (Sao Paulo, Brazil)
Liu, Zhi-Dan ZD; Wang, Song-Quan SQ; Li, Sai S; He, Jie J; Wang, Shao-Hua SH; Cai, Hong-Qing HQ; Wan, Jing-Hai JH
Publication Date: 2023-05-16

Variant appearance in text: EGFR: Leu858Arg
PubMed Link: 37201304
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Utilisation Patterns and Treatment Outcomes of EGFR-Tyrosine Kinase Inhibitors in EGFR-mutant Advanced Lung Carcinoma in the Pakistani-Asian Population: A Real-world Data Study.

Journal Of Cancer & Allied Specialties
Munawar, Kiran K; Qazi, Romena R; Sheikh, Hassan Shahryar HS
Publication Date: 2023

Variant appearance in text: EGFR: L858R
PubMed Link: 37196999
Variant Present in the following documents:
  • JCAS-9-491.pdf
View BVdb publication page



Advanced Non-small Cell Lung Cancer: EGFR Mutation Analysis Using Pyrosequencing and the Fully Automated qPCR-Based IdyllaTM System.

Cancer Control : Journal Of The Moffitt Cancer Center
Boustany, Youssra Y; Laraqui, Abdelilah A; El Zaitouni, Sara S; Ghaouti, Merieme M; Benzekri, Asmae A; Kettani, Fouad F; Oukabli, Mohammed M; Ennibi, Khalid K; Belkadi, Bouchra B; Sekhsokh, Yassine Y
Publication Date: 2023

Variant appearance in text: EGFR: L858R
PubMed Link: 37196225
Variant Present in the following documents:
  • Main text
  • 10.1177_10732748231177538.pdf
View BVdb publication page



Synthesis and Development of Highly Selective Pyrrolo[2,3-d]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form.

Journal Of Medicinal Chemistry
Aarhus, Thomas Ihle TI; Bjørnstad, Frithjof F; Wolowczyk, Camilla C; Larsen, Kristin Uhlving KU; Rognstad, Line L; Leithaug, Trygve T; Unger, Anke A; Habenberger, Peter P; Wolf, Alexander A; Bjørkøy, Geir G; Pridans, Clare C; Eickhoff, Jan J; Klebl, Bert B; Hoff, Bård H BH; Sundby, Eirik E
Publication Date: 2023-05-16

Variant appearance in text: EGFR: L858R
PubMed Link: 37191268
Variant Present in the following documents:
  • jm3c00428_si_001.pdf
View BVdb publication page



Retrospective Analysis of the Incidence of Drug-Induced Interstitial Lung Disease by Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Survival in Patients Aged 75 Years or Older with Lung Cancer.

Jma Journal
Ishibashi, Masayuki M; Nakagawa, Yoshiko Y; Shimizu, Tetsuo T; Gon, Yasuhiro Y; Yamamoto, Hiroshi H
Publication Date: 2023-04-14

Variant appearance in text: EGFR: L858R
PubMed Link: 37179737
Variant Present in the following documents:
  • 2433-3298-6-2-0182.pdf
View BVdb publication page



Performance of Ultra-Rapid Idylla™ EGFR Mutation Test in Non-Small-Cell Lung Cancer and Its Potential at Clinical Molecular Screening.

Cancers
Suda, Kenichi K; Sakai, Kazuko K; Ohira, Tatsuo T; Chikugo, Takaaki T; Satou, Takao T; Matsubayashi, Jun J; Nagao, Toshitaka T; Ikeda, Norihiko N; Tsutani, Yasuhiro Y; Mitsudomi, Tetsuya T; Nishio, Kazuto K
Publication Date: 2023-05-07

Variant appearance in text: EGFR: L858R
PubMed Link: 37174112
Variant Present in the following documents:
  • Main text
  • cancers-15-02648.pdf
View BVdb publication page



Pan-cancer whole-genome comparison of primary and metastatic solid tumours.

Nature
Martínez-Jiménez, Francisco F; Movasati, Ali A; Brunner, Sascha Remy SR; Nguyen, Luan L; Priestley, Peter P; Cuppen, Edwin E; Van Hoeck, Arne A
Publication Date: 2023-05-10

Variant appearance in text: EGFR: L858R
PubMed Link: 37165194
Variant Present in the following documents:
  • 41586_2023_6054_MOESM3_ESM.pdf
  • 41586_2023_6054_MOESM12_ESM.xlsx, sheet 5
  • 41586_2023_Article_6054.pdf
  • 41586_2023_6054_MOESM1_ESM.pdf
View BVdb publication page



Aberrant m5C hypermethylation mediates intrinsic resistance to gefitinib through NSUN2/YBX1/QSOX1 axis in EGFR-mutant non-small-cell lung cancer.

Molecular Cancer
Wang, Yueqin Y; Wei, Jingyao J; Feng, Luyao L; Li, Ouwen O; Huang, Lan L; Zhou, Shaoxuan S; Xu, Yingjie Y; An, Ke K; Zhang, Yu Y; Chen, Ruiying R; He, Lulu L; Wang, Qiming Q; Wang, Han H; Du, Yue Y; Liu, Ruijuan R; Huang, Chunmin C; Zhang, Xiaojian X; Yang, Yun-Gui YG; Kan, Quancheng Q; Tian, Xin X
Publication Date: 2023-05-09

Variant appearance in text: EGFR: L858R
PubMed Link: 37161388
Variant Present in the following documents:
  • Main text
  • 12943_2023_Article_1780.pdf
View BVdb publication page



LncRNA LINC00969 promotes acquired gefitinib resistance by epigenetically suppressing of NLRP3 at transcriptional and posttranscriptional levels to inhibit pyroptosis in lung cancer.

Cell Death & Disease
Dai, Jiali J; Qu, Tianyu T; Yin, Dandan D; Cui, Yanan Y; Zhang, Chen C; Zhang, Erbao E; Guo, Renhua R
Publication Date: 2023-05-08

Variant appearance in text: EGFR: L858R
PubMed Link: 37156816
Variant Present in the following documents:
  • Main text
  • 41419_2023_Article_5840.pdf
View BVdb publication page



CheckMate-722: The Rise and Fall of Nivolumab with Chemotherapy in TKI-Refractory EGFR-Mutant NSCLC.

Lung Cancer (Auckland, N.Z.)
Lee, Alexandria T M ATM; Nagasaka, Misako M
Publication Date: 2023

Variant appearance in text: EGFR: L858R
PubMed Link: 37138950
Variant Present in the following documents:
  • Main text
  • lctt-14-41.pdf
View BVdb publication page



Central nervous system efficacy of furmonertinib (AST2818) in patients with EGFR T790M mutated non-small cell lung cancer: a pooled analysis from two phase 2 studies.

Bmc Medicine
Hu, Xingsheng X; Zhang, Shucai S; Ma, Zhiyong Z; Feng, Jifeng J; Wu, Lin L; Lv, Dongqing D; Zhou, Jianying J; Zhang, Xiaodong X; Liu, Li L; Yu, Qitao Q; Liao, Wangjun W; Zhang, Yiping Y; Wang, Xiang X; Cheng, Ying Y; Niu, Hongrui H; Wang, Ziping Z; Wang, Dong D; Huang, Cheng C; Liu, Chunling C; Zhao, Hui H; Feng, Jian J; Li, Jingzhang J; Ying, Kejing K; Yang, Nong N; Qin, Shukui S; Hu, Jie J; Liu, Fei F; Jiang, Yong Y; Ge, Nan N; Shi, Yuankai Y
Publication Date: 2023-04-28

Variant appearance in text: EGFR: L858R
PubMed Link: 37118803
Variant Present in the following documents:
  • Main text
  • 12916_2023_Article_2865.pdf
View BVdb publication page



Human Papillomavirus Infection and EGFR Exon 20 Insertions in Sinonasal Inverted Papilloma and Squamous Cell Carcinoma.

Journal Of Personalized Medicine
Hirakawa, Hitoshi H; Ikegami, Taro T; Kise, Norimoto N; Kinjyo, Hidetoshi H; Kondo, Shunsuke S; Agena, Shinya S; Hasegawa, Narumi N; Kawakami, Junko J; Maeda, Hiroyuki H; Suzuki, Mikio M
Publication Date: 2023-04-11

Variant appearance in text: EGFR: L858R
PubMed Link: 37109043
Variant Present in the following documents:
  • Main text
  • jpm-13-00657.pdf
View BVdb publication page



A new class of anti-proliferative activity and apoptotic inducer with molecular docking studies for a novel of 1,3-dithiolo[4,5-b]quinoxaline derivatives hybrid with a sulfonamide moiety.

Rsc Advances
Ismail, Mostafa A MA; Abusaif, Moustafa S MS; El-Gaby, Mohamed S A MSA; Ammar, Yousry A YA; Ragab, Ahmed A
Publication Date: 2023-04-17

Variant appearance in text: EGFR: L858R
PubMed Link: 37101951
Variant Present in the following documents:
  • Main text
  • RA-013-D3RA01635H.pdf
  • RA-013-D3RA01635H-s001.pdf
View BVdb publication page



Challenges of EGFR-TKIs in NSCLC and the potential role of herbs and active compounds: From mechanism to clinical practice.

Frontiers In Pharmacology
Song, Xiaotong X; Cao, Luchang L; Ni, Baoyi B; Wang, Jia J; Qin, Xiaoyan X; Sun, Xiaoyue X; Xu, Bowen B; Wang, Xinmiao X; Li, Jie J
Publication Date: 2023

Variant appearance in text: EGFR: L858R
PubMed Link: 37089959
Variant Present in the following documents:
  • Main text
  • fphar-14-1090500.pdf
View BVdb publication page



Highly Mimetic Ex Vivo Lung-Cancer Spheroid-Based Physiological Model for Clinical Precision Therapeutics.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
Shie, Ming-You MY; Fang, Hsin-Yuan HY; Kan, Kai-Wen KW; Ho, Chia-Che CC; Tu, Chih-Yen CY; Lee, Pei-Chih PC; Hsueh, Po-Ren PR; Chen, Chia-Hung CH; Lee, Alvin Kai-Xing AK; Tien, Ni N; Chen, Jian-Xun JX; Shen, Yu-Cheng YC; Chang, Jan-Gowth JG; Shen, Yu-Fang YF; Lin, Ting-Ju TJ; Wang, Ben B; Hung, Mien-Chie MC; Cho, Der-Yang DY; Chen, Yi-Wen YW
Publication Date: 2023-04-21

Variant appearance in text: EGFR: L858R
PubMed Link: 37085943
Variant Present in the following documents:
  • ADVS-10-2206603.pdf
  • ADVS-10-2206603-s001.pdf
View BVdb publication page



Advances in the Treatment of Rare Epidermal Growth Factor Receptor Mutations in Advanced Nonsmall-Cell Lung Cancer.

Technology In Cancer Research & Treatment
Yu, Limeng L; Wang, Ruilin R; Zhao, Yuhua Y; Wu, Yingxi Y; Wang, Lili L; Chen, Haiyang H; He, Zhen Z; Wang, Qiming Q; Wu, Yufeng Y
Publication Date: 2023

Variant appearance in text: EGFR: L858R
PubMed Link: 37078129
Variant Present in the following documents:
  • Main text
  • 10.1177_15330338231168466.pdf
View BVdb publication page



The Use of Cytotoxic Drugs as First Line Chemotherapy for EGFR (+) Nonsquamous NSCLC: A Network Meta-Analysis.

Disease Markers
Li, Duo D; Li, Meng M; Li, Hong H; Shi, Puyu P; Chen, Mingwei M; Yang, Tian T
Publication Date: 2023

Variant appearance in text: EGFR: L858R
PubMed Link: 37077340
Variant Present in the following documents:
  • DM2023-5272125.pdf
View BVdb publication page



Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.

Nature
Abbosh, Christopher C; Frankell, Alexander M AM; Harrison, Thomas T; Kisistok, Judit J; Garnett, Aaron A; Johnson, Laura L; Veeriah, Selvaraju S; Moreau, Mike M; Chesh, Adrian A; Chaunzwa, Tafadzwa L TL; Weiss, Jakob J; Schroeder, Morgan R MR; Ward, Sophia S; Grigoriadis, Kristiana K; Shahpurwalla, Aamir A; Litchfield, Kevin K; Puttick, Clare C; Biswas, Dhruva D; Karasaki, Takahiro T; Black, James R M JRM; Martínez-Ruiz, Carlos C; Bakir, Maise Al MA; Pich, Oriol O; Watkins, Thomas B K TBK; Lim, Emilia L EL; Huebner, Ariana A; Moore, David A DA; Godin-Heymann, Nadia N; L'Hernault, Anne A; Bye, Hannah H; Odell, Aaron A; Roberts, Paula P; Gomes, Fabio F; Patel, Akshay J AJ; Manzano, Elizabeth E; Hiley, Crispin T CT; Carey, Nicolas N; Riley, Joan J; Cook, Daniel E DE; Hodgson, Darren D; Stetson, Daniel D; Barrett, J Carl JC; Kortlever, Roderik M RM; Evan, Gerard I GI; Hackshaw, Allan A; Daber, Robert D RD; Shaw, Jacqui A JA; Aerts, Hugo J W L HJWL; Licon, Abel A; Stahl, Josh J; Jamal-Hanjani, Mariam M; , ; Birkbak, Nicolai J NJ; McGranahan, Nicholas N; Swanton, Charles C
Publication Date: 2023-04-13

Variant appearance in text: EGFR: L858R
PubMed Link: 37055640
Variant Present in the following documents:
  • EMS176197-supplement-Supplementary_Table_1.xlsx, sheet 18
View BVdb publication page



Ramucirumab Plus Docetaxel for Patients with Non-small cell Lung Cancer with Brain Metastases: A Multicenter, Open-Label Single-Arm Phase II Trial.

The Oncologist
Tanimura, Keiko K; Uchino, Junji J; Kimura, Hideharu H; Hiranuma, Osamu O; Chihara, Yusuke Y; Tanzawa, Shigeru S; Takumi, Chieko C; Kita, Toshiyuki T; Inoue, Koji K; Minato, Koichi K; Takemoto, Shinnosuke S; Nakao, Akira A; Yoshimura, Kenichi K; Takayama, Koichi K
Publication Date: 2023-04-13

Variant appearance in text: EGFR: L858R
PubMed Link: 37053467
Variant Present in the following documents:
  • Main text
  • oyad013.pdf
View BVdb publication page



The evolution of non-small cell lung cancer metastases in TRACERx.

Nature
Al Bakir, Maise M; Huebner, Ariana A; Martínez-Ruiz, Carlos C; Grigoriadis, Kristiana K; Watkins, Thomas B K TBK; Pich, Oriol O; Moore, David A DA; Veeriah, Selvaraju S; Ward, Sophia S; Laycock, Joanne J; Johnson, Diana D; Rowan, Andrew A; Razaq, Maryam M; Akther, Mita M; Naceur-Lombardelli, Cristina C; Prymas, Paulina P; Toncheva, Antonia A; Hessey, Sonya S; Dietzen, Michelle M; Colliver, Emma E; Frankell, Alexander M AM; Bunkum, Abigail A; Lim, Emilia L EL; Karasaki, Takahiro T; Abbosh, Christopher C; Hiley, Crispin T CT; Hill, Mark S MS; Cook, Daniel E DE; Wilson, Gareth A GA; Salgado, Roberto R; Nye, Emma E; Stone, Richard Kevin RK; Fennell, Dean A DA; Price, Gillian G; Kerr, Keith M KM; Naidu, Babu B; Middleton, Gary G; Summers, Yvonne Y; Lindsay, Colin R CR; Blackhall, Fiona H FH; Cave, Judith J; Blyth, Kevin G KG; Nair, Arjun A; Ahmed, Asia A; Taylor, Magali N MN; Procter, Alexander James AJ; Falzon, Mary M; Lawrence, David D; Navani, Neal N; Thakrar, Ricky M RM; Janes, Sam M SM; Papadatos-Pastos, Dionysis D; Forster, Martin D MD; Lee, Siow Ming SM; Ahmad, Tanya T; Quezada, Sergio A SA; Peggs, Karl S KS; Van Loo, Peter P; Dive, Caroline C; Hackshaw, Allan A; Birkbak, Nicolai J NJ; Zaccaria, Simone S; , ; Jamal-Hanjani, Mariam M; McGranahan, Nicholas N; Swanton, Charles C
Publication Date: 2023-04-12

Variant appearance in text: EGFR: L858R
PubMed Link: 37046095
Variant Present in the following documents:
  • Main text
  • 41586_2023_Article_5729.pdf
View BVdb publication page



Biomarker expression and survival in patients with non-small cell lung cancer receiving adjuvant chemotherapy in Denmark.

Plos One
Dalvi, Tapashi T; Nørgaard, Mette M; Fryzek, Jon P JP; Movva, Naimisha N; Pedersen, Lars L; Pham Hansen, Hanh H; Walker, Jill J; Midha, Anita A; Shire, Norah N; Boothman, Anne-Marie AM; Rigas, James J; Mellemgaard, Anders A; Rasmussen, Torben R TR; Hamilton-Dutoit, Stephen S; Cronin-Fenton, Deirdre D
Publication Date: 2023

Variant appearance in text: EGFR: L858R
PubMed Link: 37040387
Variant Present in the following documents:
  • Main text
  • pone.0284037.pdf
View BVdb publication page



Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.

Cancer Medicine
Montes-Rodríguez, Ingrid M IM; Centeno-Girona, Hilmaris H; Rivera-Lynch, Camila C; Rivera, Noridza N; Cruz-Correa, Marcia M
Publication Date: 2023-04-11

Variant appearance in text: EGFR: L858R
PubMed Link: 37039257
Variant Present in the following documents:
  • CAM4-12-11686-s002.xlsx, sheet 1
View BVdb publication page



[A Real-world Study on the Expression Characteristics of PD-L1 in Patients 
with Advanced EGFR Positive NSCLC and Its Relationship with the 
Therapeutic Efficacy of EGFR-TKIs].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Chen, Ran R; Gao, Xiang X; Xu, Fudong F; Zhang, Shucai S; Ma, Li L; Hu, Bo B
Publication Date: 2023-03-20

Variant appearance in text: EGFR: L858R
PubMed Link: 37035884
Variant Present in the following documents:
  • zgfazz-26-3-217.pdf
View BVdb publication page



Nanoparticles overcome adaptive immune resistance and enhance immunotherapy via targeting tumor microenvironment in lung cancer.

Frontiers In Pharmacology
Zhang, Xin X; Wang, Xuemei X; Hou, Lijian L; Xu, Zheng Z; Liu, Yu'e Y; Wang, Xueju X
Publication Date: 2023

Variant appearance in text: EGFR: L858R
PubMed Link: 37033636
Variant Present in the following documents:
  • Main text
  • fphar-14-1130937.pdf
View BVdb publication page



Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones.

Journal Of Medicinal Chemistry
Harnden, Alice C AC; Davis, Owen A OA; Box, Gary M GM; Hayes, Angela A; Johnson, Louise D LD; Henley, Alan T AT; de Haven Brandon, Alexis K AK; Valenti, Melanie M; Cheung, Kwai-Ming J KJ; Brennan, Alfie A; Huckvale, Rosemary R; Pierrat, Olivier A OA; Talbot, Rachel R; Bright, Michael D MD; Akpinar, Hafize Aysin HA; Miller, Daniel S J DSJ; Tarantino, Dalia D; Gowan, Sharon S; de Klerk, Selby S; McAndrew, Peter Craig PC; Le Bihan, Yann-Vaï YV; Meniconi, Mirco M; Burke, Rosemary R; Kirkin, Vladimir V; van Montfort, Rob L M RLM; Raynaud, Florence I FI; Rossanese, Olivia W OW; Bellenie, Benjamin R BR; Hoelder, Swen S
Publication Date: 2023-04-07

Variant appearance in text: EGFR: L858R
PubMed Link: 37026591
Variant Present in the following documents:
  • jm3c00155_si_002.xlsx, sheet 2
View BVdb publication page



T790M and Acquired Resistance of Epidermal Growth Factor Receptor to Tyrosine Kinase Inhibitors in Patients with Lung Adenocarcinoma.

Tanaffos
Mirtavoos-Mahyari, Hanifeh H; Abbasi Dezfouli, Azizollah A; Esfahani-Monfared, Zahra Z; Khosravi, Adnan A; Seifi, Sharareh S; Sheikhy, Kambiz K
Publication Date: 2022-03

Variant appearance in text: EGFR: L858R
PubMed Link: 37025321
Variant Present in the following documents:
  • Main text
  • Tanaffos-21-376.pdf
View BVdb publication page



Osimertinib combined with bevacizumab as the first-line treatment in non-small cell lung cancer patients with brain metastasis harboring epidermal growth factor receptor mutations.

Thoracic Cancer
Zhang, Ling L; You, Yunhong Y; Liu, Xueli X; Liu, Fengjuan F; Nie, Keke K; Ji, Youxin Y
Publication Date: 2023-04-05

Variant appearance in text: EGFR: L858R
PubMed Link: 37016906
Variant Present in the following documents:
  • Main text
  • TCA-14-1355.pdf
View BVdb publication page



Identification of EGFR mutation status in male patients with non-small-cell lung cancer: role of 18F-FDG PET/CT and serum tumor markers CYFRA21-1 and SCC-Ag.

Ejnmmi Research
Jiang, Maoqing M; Chen, Ping P; Guo, Xiuyu X; Zhang, Xiaohui X; Gao, Qiaoling Q; Zhang, Jingfeng J; Zhao, Guofang G; Zheng, Jianjun J
Publication Date: 2023-04-04

Variant appearance in text: EGFR: L858R
PubMed Link: 37014455
Variant Present in the following documents:
  • 13550_2023_Article_976.pdf
View BVdb publication page



Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: EGFR: L858R
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 2
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 4
View BVdb publication page



Precision targeted therapy for EGFR mutation-positive NSCLC: Dilemmas and coping strategies.

Thoracic Cancer
Meng, Ying Y; Bai, Rilan R; Cui, Jiuwei J
Publication Date: 2023-04-02

Variant appearance in text: EGFR: L858R
PubMed Link: 37005552
Variant Present in the following documents:
  • Main text
  • TCA-14-1121.pdf
View BVdb publication page



In-depth proteomics reveals the characteristic developmental profiles of early lung adenocarcinoma with epidermal growth factor receptor mutation.

Cancer Medicine
Dai, Tomoko T; Adachi, Jun J; Dai, Yuichi Y; Nakano, Noriyuki N; Yamato, Mariko M; Kikuchi, Shinji S; Usui, Shingo S; Minami, Yuko Y; Tomonaga, Takeshi T; Noguchi, Masayuki M; Matsubara, Daisuke D; Sakamoto, Noriaki N
Publication Date: 2023-04-02

Variant appearance in text: EGFR: L858R
PubMed Link: 37004157
Variant Present in the following documents:
  • Main text
  • CAM4-12-10755.pdf
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Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer
Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J
Publication Date: 2023-03-31

Variant appearance in text: EGFR: Leu858Arg
PubMed Link: 37004022
Variant Present in the following documents:
  • 12885_2023_10674_MOESM1_ESM.xlsx, sheet 1
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