Beneficial effects of mifepristone treatment in breast cancer patients selected by the progesterone receptor isoform ratio: Results from the MIPRA trial.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Elía, Andrés A; Saldain, Leo L; Vanzulli, Silvia I SI; Helguero, Luisa A LA; Lamb, Caroline A CA; Fabris, Victoria V; Pataccini, Gabriela G; Martínez-Vazquez, Paula P; Burruchaga, Javier J; Caillet-Bois, Ines I; Spengler, Eunice E; Acosta Haab, Gabriela G; Liguori, Marcos M; Castets, Alejandra A; Lovisi, Silvia S; Abascal, María F MF; Novaro, Virginia V; Sánchez, Jana J; Muñoz, Javier J; Belizán, Jose M JM; Abba, Martín C MC; Gass, Hugo H; Rojas, Paola P; Lanari, Claudia C
Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.
Npj Systems Biology And Applications
Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A
Prediction of Nephrotoxicity Associated With Cisplatin-Based Chemotherapy in Testicular Cancer Patients.
Jnci Cancer Spectrum
Garcia, Sara L SL; Lauritsen, Jakob J; Zhang, Zeyu Z; Bandak, Mikkel M; Dalgaard, Marlene D MD; Nielsen, Rikke L RL; Daugaard, Gedske G; Gupta, Ramneek R
K-variant BCHE and pesticide exposure: Gene-environment interactions in a case-control study of Parkinson's disease in Egypt.
Scientific Reports
Rösler, Thomas W TW; Salama, Mohamed M; Shalash, Ali S AS; Khedr, Eman M EM; El-Tantawy, Abdelhalim A; Fawi, Gharib G; El-Motayam, Amal A; El-Seidy, Ehab E; El-Sherif, Mohamed M; El-Gamal, Mohamed M; Moharram, Mohamed M; El-Kattan, Mohammad M; Abdel-Naby, Muhammad M; Ashour, Samia S; Müller, Ulrich U; Dempfle, Astrid A; Kuhlenbäumer, Gregor G; Höglinger, Günter U GU
Characterization of ADME gene variation in 21 populations by exome sequencing.
Pharmacogenetics And Genomics
Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR
Fire Usage and Ancient Hominin Detoxification Genes: Protective Ancestral Variants Dominate While Additional Derived Risk Variants Appear in Modern Humans.
Plos One
Aarts, Jac M M J G JM; Alink, Gerrit M GM; Scherjon, Fulco F; MacDonald, Katharine K; Smith, Alison C AC; Nijveen, Harm H; Roebroeks, Wil W
Smoking, variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma: a pooled analysis within the InterLymph consortium.
Cancer Causes & Control : Ccc
Gibson, Todd M TM; Smedby, Karin E KE; Skibola, Christine F CF; Hein, David W DW; Slager, Susan L SL; de Sanjosé, Silvia S; Vajdic, Claire M CM; Zhang, Yawei Y; Chiu, Brian C-H BC; Wang, Sophia S SS; Hjalgrim, Henrik H; Nieters, Alexandra A; Bracci, Paige M PM; Kricker, Anne A; Zheng, Tongzhang T; Kolar, Carol C; Cerhan, James R JR; Darabi, Hatef H; Becker, Nikolaus N; Conde, Lucia L; Holford, Theodore R TR; Weisenburger, Dennis D DD; De Roos, Anneclaire J AJ; Butterbach, Katja K; Riby, Jacques J; Cozen, Wendy W; Benavente, Yolanda Y; Palmers, Casey C; Holly, Elizabeth A EA; Sampson, Joshua N JN; Rothman, Nathaniel N; Armstrong, Bruce K BK; Morton, Lindsay M LM
Using gene-environment interaction analyses to clarify the role of well-done meat and heterocyclic amine exposure in the etiology of colorectal polyps.
The American Journal Of Clinical Nutrition
Fu, Zhenming Z; Shrubsole, Martha J MJ; Li, Guoliang G; Smalley, Walter E WE; Hein, David W DW; Chen, Zhi Z; Shyr, Yu Y; Cai, Qiuyin Q; Ness, Reid M RM; Zheng, Wei W
Xenobiotic metabolizing gene variants and renal cell cancer: a multicenter study.
Frontiers In Oncology
Heck, Julia E JE; Moore, Lee E LE; Lee, Yuan-Chin A YC; McKay, James D JD; Hung, Rayjean J RJ; Karami, Sara S; Gaborieau, Valérie V; Szeszenia-Dabrowska, Neonila N; Zaridze, David G DG; Mukeriya, Anush A; Mates, Dana D; Foretova, Lenka L; Janout, Vladimir V; Kollárová, Helena H; Bencko, Vladimir V; Rothman, Nathaniel N; Brennan, Paul P; Chow, Wong-Ho WH; Boffetta, Paolo P
Polymorphic genes of detoxification and mitochondrial enzymes and risk for progressive supranuclear palsy: a case control study.
Bmc Medical Genetics
Potts, Lisa F LF; Cambon, Alex C AC; Ross, Owen A OA; Rademakers, Rosa R; Dickson, Dennis W DW; Uitti, Ryan J RJ; Wszolek, Zbigniew K ZK; Rai, Shesh N SN; Farrer, Matthew J MJ; Hein, David W DW; Litvan, Irene I
Common genetic variants in metabolism and detoxification pathways and the risk of papillary thyroid cancer.
Endocrine-Related Cancer
Aschebrook-Kilfoy, Briseis B; Neta, Gila G; Brenner, Alina V AV; Hutchinson, Amy A; Pfeiffer, Ruth M RM; Sturgis, Erich M EM; Xu, Li L; Wheeler, William W; Doody, Michele M MM; Chanock, Stephen J SJ; Sigurdson, Alice J AJ
Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans.
Arthritis And Rheumatism
Mikuls, Ted R TR; Levan, Tricia T; Gould, Karen A KA; Yu, Fang F; Thiele, Geoffrey M GM; Bynote, Kimberly K KK; Conn, Doyt D; Jonas, Beth L BL; Callahan, Leigh F LF; Smith, Edwin E; Brasington, Richard R; Moreland, Larry W LW; Reynolds, Richard R; Gaffo, Angelo A; Bridges, S Louis SL
Human N-acetyltransferase 1 *10 and *11 alleles increase protein expression through distinct mechanisms and associate with sulfamethoxazole-induced hypersensitivity.
Pharmacogenetics And Genomics
Wang, Danxin D; Para, Michael F MF; Koletar, Susan L SL; Sadee, Wolfgang W
No association between variant N-acetyltransferase genes, cigarette smoking and Prostate Cancer susceptibility among men of African descent.
Biomarkers In Cancer
Kidd, La Creis Renee LC; Vancleave, Tiva T TT; Doll, Mark A MA; Srivastava, Daya S DS; Thacker, Brandon B; Komolafe, Oyeyemi O; Pihur, Vasyl V; Brock, Guy N GN; Hein, David W DW
Xenobiotic metabolizing genes, meat-related exposures, and risk of advanced colorectal adenoma.
Journal Of Nutrigenetics And Nutrigenomics
Ferrucci, Lea M LM; Cross, Amanda J AJ; Gunter, Marc J MJ; Ahn, Jiyoung J; Mayne, Susan T ST; Ma, Xiaomei X; Chanock, Stephen J SJ; Yeager, Meredith M; Graubard, Barry I BI; Berndt, Sonja I SI; Huang, Wen-Yi WY; Hayes, Richard B RB; Sinha, Rashmi R
Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population.
American Journal Of Medical Genetics. Part A
Carter, Tonia C TC; Pangilinan, Faith F; Troendle, James F JF; Molloy, Anne M AM; VanderMeer, Julia J; Mitchell, Adam A; Kirke, Peadar N PN; Conley, Mary R MR; Shane, Barry B; Scott, John M JM; Brody, Lawrence C LC; Mills, James L JL
Xenobiotic metabolizing genes, meat-related exposures, and risk of advanced colorectal adenoma.
World Review Of Nutrition And Dietetics
Ferrucci, Leah M LM; Cross, Amanda J AJ; Gunter, Marc J MJ; Ahn, Jiyoung J; Mayne, Susan T ST; Ma, Xiaomei X; Chanock, Stephen J SJ; Yeager, Meredith M; Graubard, Barry I BI; Berndt, Sonja I SI; Huang, Wen-Yi WY; Hayes, Richard B RB; Sinha, Rashmi R
Lung cancer susceptibility model based on age, family history and genetic variants.
Plos One
Young, Robert P RP; Hopkins, Raewyn J RJ; Hay, Bryan A BA; Epton, Michael J MJ; Mills, Graham D GD; Black, Peter N PN; Gardner, Heather D HD; Sullivan, Richard R; Gamble, Gregory D GD
Genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2) and risk of non-Hodgkin lymphoma.
Pharmacogenetics And Genomics
Morton, Lindsay M LM; Schenk, Maryjean M; Hein, David W DW; Davis, Scott S; Zahm, Shelia Hoar SH; Cozen, Wendy W; Cerhan, James R JR; Hartge, Patricia P; Welch, Robert R; Chanock, Stephen J SJ; Rothman, Nathaniel N; Wang, Sophia S SS
Analysis of candidate modifier loci for the severity of colonic familial adenomatous polyposis, with evidence for the importance of the N-acetyl transferases.
Gut
Crabtree, M D MD; Fletcher, C C; Churchman, M M; Hodgson, S V SV; Neale, K K; Phillips, R K S RK; Tomlinson, I P M IP