An A666G mutation in transmembrane helix 5 of the yeast multidrug transporter Pdr5 increases drug efflux by enhancing cooperativity between transport sites.
Molecular Microbiology
Arya, Nidhi N; Rahman, Hadiar H; Rudrow, Andrew A; Wagner, Manuel M; Schmitt, Lutz L; Ambudkar, Suresh V SV; Golin, John J